Lista de obras - F Debart - Dominio Público Uruguay

1H and 31P-NMR assignments of the non-exchangeable protons of the consensus acceptor exon:intron junction d(CpTpApCpApGpGpT)

scientific article published on 01 June 1986

5-Propynylamino α-deoxyuridine promotes DNA duplex stabilization of anionic and neutral but not cationic α-oligonucleotides

scientific article published on 18 November 2006

A 2′,2′-disulfide-bridged dinucleotide conformationally locks RNA hairpins

artículo científico publicado en 2018

A Whole Base-Labile Strategy for RNA Synthesis with 2'-O-acetalester Protections

scientific article published on 01 January 2008

A versatile post-synthetic method on a solid support for the synthesis of RNA containing reduction-responsive modifications.

artículo científico publicado en 2016

Anomeric inversion (from beta to alpha) in methylphosphonate oligonucleosides enhances their affinity for DNA and RNA.

artículo científico publicado en 1998

Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates

artículo científico publicado en 2013

Binding of the Methyl Donor S-Adenosyl-l-Methionine to Middle East Respiratory Syndrome Coronavirus 2'-O-Methyltransferase nsp16 Promotes Recruitment of the Allosteric Activator nsp10.

artículo científico publicado en 2016

Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress

artículo científico publicado en 2017

Combining Chemical Synthesis and Enzymatic Methylation to Access Short RNAs with Various 5' Caps

artículo científico publicado en 2019

Conjugation of Doxorubicin to siRNA Through Disulfide-based Self-immolative Linkers

artículo científico publicado en 2020

Development of specific dengue virus 2'-O- and N7-methyltransferase assays for antiviral drug screening.

artículo científico publicado en 2013

Direct synthesis of partially modified 2'-O-pivaloyloxymethyl RNAs by a base-labile protecting group strategy and their potential for prodrug-based gene-silencing applications

artículo científico publicado en 2014

Efficient Solid-Phase Chemical Synthesis of 5′-Triphosphates of DNA, RNA, and their Analogues

scientific article published on 01 May 2010

Esterase-triggered fluorescence of fluorogenic oligonucleotides.

artículo científico publicado en 1997

FTIR and UV spectroscopy studies of triplex formation between alpha-oligonucleotides with non-ionic phoshoramidate linkages and DNA targets.

artículo científico publicado en 2003

FTIR and UV spectroscopy studies of triplex formation between pyrimidine methoxyethylphosphoramidates alpha-oligodeoxynucleotides and ds DNA targets.

artículo científico publicado en 2002

FTO controls reversible m6Am RNA methylation during snRNA biogenesis

scientific article published on 18 February 2019

FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell

artículo científico publicado en 2021

First Evaluation of Acyloxymethyl or Acylthiomethyl Groups as Biolabile 2‘-O-Protections of RNA†

artículo científico publicado en 2006

Gymnotic delivery and gene silencing activity of reduction-responsive siRNAs bearing lipophilic disulfide-containing modifications at 2′-position

article

Highly stable DNA triplexes formed with cationic phosphoramidate pyrimidine alpha-oligonucleotides.

artículo científico publicado en 2005

Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome

scientific article published on 03 July 2019

Imidazolethyl-phosphoramidate alpha-oligonucleotides.

artículo científico

La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region.

artículo científico publicado en 2017

Lipophilic 2'-O-Acetal Ester RNAs: Synthesis, Thermal Duplex Stability, Nuclease Resistance, Cellular Uptake, and siRNA Activity after Spontaneous Naked Delivery.

artículo científico publicado en 2016

Molecular basis for nucleotide conservation at the ends of the dengue virus genome.

artículo científico publicado en 2012

Novel strategies towards construction of non-ionic and achiral backbones in antisense oligonucleotides ⬇️

artículo científico publicado el 1 de enero de 1992

Potent Inhibition of SARS-CoV-2 nsp14 N7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues

artículo científico publicado en 2022

Step-by-step control by MALDI-TOF MS of an oligonucleotide synthesis on standard CPG solid-support.

artículo científico publicado en 2001

Stimuli-responsive oligonucleotides in prodrug-based approaches for gene silencing.

artículo científico publicado en 2018

Structure and conformation of the duplex consensus 5'-splice site d[(CpApGpGpTpApApGpT).(ApCpTpTpApCpCpTpG)] deduced from high field 1H-NMR of the non-exchangeable and imino protons

artículo científico publicado en 1987

Structure and conformation of the duplex consensus acceptor exon:intron junction d[(CpTpApCpApGpGpT). (ApCpCpTpGpTpApG)] deduced from high-field 1H-NMR of non-exchangeable and imino protons

scientific article published on 01 December 1986

Synthesis and Preliminary Evaluation of pro-RNA 2′-O-Masked with Biolabile Pivaloyloxymethyl Groups in an RNA Interference Assay

artículo científico publicado en 2011

Synthesis of 5' cap-0 and cap-1 RNAs using solid-phase chemistry coupled with enzymatic methylation by human (guanine-N⁷)-methyl transferase.

artículo científico publicado en 2012

Synthesis, DNA binding, and biological evaluation of synthetic precursors and novel analogues of netropsin

artículo científico publicado en 1989

Synthesis, binding, nuclease resistance and cellular uptake properties of 2'-O-acetalester-modified oligonucleotides containing cationic groups

artículo científico

The methyltransferase domain of the Respiratory Syncytial Virus L protein catalyzes cap N7 and 2'-O-methylation

artículo científico publicado en 2021

The methyltransferase domain of the Sudan ebolavirus L protein specifically targets internal adenosines of RNA substrates, in addition to the cap structure

article

Toward high yield synthesis of peptide-oligonucleotide chimera through a disulfide bridge: a simplified method for oligonucleotide activation.

artículo científico publicado en 2005

Toward the identification of viral cap-methyltransferase inhibitors by fluorescence screening assay

artículo científico publicado en 2017

Use of MALDI-TOF mass spectrometry to monitor solid-phase synthesis of oligonucleotides

artículo científico publicado en 2002

X-ray structure and activities of an essential Mononegavirales L-protein domain

artículo científico publicado en 2015

[Ebola virus L protein harbors a new enzymatic activity involved in the internal methylation of RNAs].

artículo científico publicado en 2018

mRNA maturation in giant viruses: variation on a theme.

artículo científico publicado en 2015

α-OLIGONUCLEOTIDES WITH ANIONIC PHOSPHODIESTER AND CATIONIC PHOSPHORAMIDATE LINKAGES ENHANCED STABILITY OF DNA TRIPLE HELIX

scientific article published on 01 April 2001

Lista de obras de F Debart

1H and 31P-NMR assignments of the non-exchangeable protons of the consensus acceptor exon:intron junction d(CpTpApCpApGpGpT)

5-Propynylamino α-deoxyuridine promotes DNA duplex stabilization of anionic and neutral but not cationic α-oligonucleotides

A 2′,2′-disulfide-bridged dinucleotide conformationally locks RNA hairpins

A Whole Base-Labile Strategy for RNA Synthesis with 2'-O-acetalester Protections

A versatile post-synthetic method on a solid support for the synthesis of RNA containing reduction-responsive modifications.

Anomeric inversion (from beta to alpha) in methylphosphonate oligonucleosides enhances their affinity for DNA and RNA.

Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates

Binding of the Methyl Donor S-Adenosyl-l-Methionine to Middle East Respiratory Syndrome Coronavirus 2'-O-Methyltransferase nsp16 Promotes Recruitment of the Allosteric Activator nsp10.

Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress

Combining Chemical Synthesis and Enzymatic Methylation to Access Short RNAs with Various 5' Caps

Conjugation of Doxorubicin to siRNA Through Disulfide-based Self-immolative Linkers

Development of specific dengue virus 2'-O- and N7-methyltransferase assays for antiviral drug screening.

Direct synthesis of partially modified 2'-O-pivaloyloxymethyl RNAs by a base-labile protecting group strategy and their potential for prodrug-based gene-silencing applications

Efficient Solid-Phase Chemical Synthesis of 5′-Triphosphates of DNA, RNA, and their Analogues

Esterase-triggered fluorescence of fluorogenic oligonucleotides.

FTIR and UV spectroscopy studies of triplex formation between alpha-oligonucleotides with non-ionic phoshoramidate linkages and DNA targets.

FTIR and UV spectroscopy studies of triplex formation between pyrimidine methoxyethylphosphoramidates alpha-oligodeoxynucleotides and ds DNA targets.

FTO controls reversible m6Am RNA methylation during snRNA biogenesis

FTO-mediated cytoplasmic m<sup>6</sup>A<sub>m</sub> demethylation adjusts stem-like properties in colorectal cancer cell

First Evaluation of Acyloxymethyl or Acylthiomethyl Groups as Biolabile 2‘-O-Protections of RNA†

Gymnotic delivery and gene silencing activity of reduction-responsive siRNAs bearing lipophilic disulfide-containing modifications at 2′-position

Highly stable DNA triplexes formed with cationic phosphoramidate pyrimidine alpha-oligonucleotides.

Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome

Imidazolethyl-phosphoramidate alpha-oligonucleotides.

La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region.

Lipophilic 2'-O-Acetal Ester RNAs: Synthesis, Thermal Duplex Stability, Nuclease Resistance, Cellular Uptake, and siRNA Activity after Spontaneous Naked Delivery.

Molecular basis for nucleotide conservation at the ends of the dengue virus genome.

Novel strategies towards construction of non-ionic and achiral backbones in antisense oligonucleotides ⬇️

Potent Inhibition of SARS-CoV-2 nsp14 <i>N</i>7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues

Step-by-step control by MALDI-TOF MS of an oligonucleotide synthesis on standard CPG solid-support.

Stimuli-responsive oligonucleotides in prodrug-based approaches for gene silencing.

Structure and conformation of the duplex consensus 5'-splice site d[(CpApGpGpTpApApGpT).(ApCpTpTpApCpCpTpG)] deduced from high field 1H-NMR of the non-exchangeable and imino protons

Structure and conformation of the duplex consensus acceptor exon:intron junction d[(CpTpApCpApGpGpT). (ApCpCpTpGpTpApG)] deduced from high-field 1H-NMR of non-exchangeable and imino protons

Synthesis and Preliminary Evaluation of pro-RNA 2′-O-Masked with Biolabile Pivaloyloxymethyl Groups in an RNA Interference Assay

Synthesis of 5' cap-0 and cap-1 RNAs using solid-phase chemistry coupled with enzymatic methylation by human (guanine-N⁷)-methyl transferase.

Synthesis, DNA binding, and biological evaluation of synthetic precursors and novel analogues of netropsin

Synthesis, binding, nuclease resistance and cellular uptake properties of 2'-O-acetalester-modified oligonucleotides containing cationic groups

The methyltransferase domain of the Respiratory Syncytial Virus L protein catalyzes cap N7 and 2'-O-methylation

The methyltransferase domain of the Sudan ebolavirus L protein specifically targets internal adenosines of RNA substrates, in addition to the cap structure

Toward high yield synthesis of peptide-oligonucleotide chimera through a disulfide bridge: a simplified method for oligonucleotide activation.

Toward the identification of viral cap-methyltransferase inhibitors by fluorescence screening assay

Use of MALDI-TOF mass spectrometry to monitor solid-phase synthesis of oligonucleotides

X-ray structure and activities of an essential Mononegavirales L-protein domain

[Ebola virus L protein harbors a new enzymatic activity involved in the internal methylation of RNAs].

mRNA maturation in giant viruses: variation on a theme.

α-OLIGONUCLEOTIDES WITH ANIONIC PHOSPHODIESTER AND CATIONIC PHOSPHORAMIDATE LINKAGES ENHANCED STABILITY OF DNA TRIPLE HELIX