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Lista de obras de Harm H Kampinga

A PCR amplification strategy for unrestricted generation of chimeric genes.

artículo científico publicado en 2008

A long-term flow cytometry assay to analyze the role of specific genes of Drosophila melanogaster S2 cells in surviving genotoxic stress

artículo científico publicado en 2008

Acquisition of thermotolerance induced by heat and arsenite in HeLa S3 cells: multiple pathways to induce tolerance?

artículo científico publicado el 1 de febrero de 1992

Alteration of protein folding and degradation in motor neuron diseases: Implications and protective functions of small heat shock proteins.

artículo científico publicado en 2011

An Image Analysis Technique for Detection of Radiation-induced DNA Fragmentation after CHEF Electrophoresis

artículo científico publicado en 1993

BAG3 directly interacts with mutated alphaB-crystallin to suppress its aggregation and toxicity

artículo científico publicado en 2011

BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: implications for a proteasome-to-autophagy switch.

artículo científico publicado en 2014

BRCA1 and BRCA2 heterozygosity and repair of X-ray-induced DNA damage

artículo científico publicado en 2002

Barcoding heat shock proteins to human diseases: looking beyond the heat shock response

artículo científico

Beat shock proteins and atrial fibrillation.

artículo científico publicado en 2007

Brain death induces renal expression of heme oxygenase-1 and heat shock protein 70.

artículo científico publicado en 2013

Calpain inhibition prevents pacing-induced cellular remodeling in a HL-1 myocyte model for atrial fibrillation.

artículo científico publicado en 2004

Cell biological effects of hyperthermia alone or combined with radiation or drugs: a short introduction to newcomers in the field.

artículo científico publicado en 2006

Cell biology. A cell death avenue evolved from a life-saving path

scientific article published on 01 June 2014

Cells overexpressing Hsp27 show accelerated recovery from heat-induced nuclear protein aggregation.

artículo científico publicado en 1994

Cellular protein quality control and the evolution of aggregates in spinocerebellar ataxia type 3 (SCA3).

artículo científico publicado en 2012

Changes in expression of injury after irradiation of increasing volumes in rat lung.

artículo científico publicado en 2007

Chaperoned by prebiotic inorganic polyphosphate molecules: an ancient transcription-independent mechanism to restore protein homeostasis.

artículo científico publicado en 2014

Chaperones in Polyglutamine Aggregation: Beyond the Q-Stretch.

artículo científico publicado en 2017

Chemo- and radiosensitivity testing in a patient with ataxia telangiectasia and Hodgkin disease.

artículo científico publicado en 2002

Comparison of three rat strains for development of radiation-induced lung injury after hemithoracic irradiation

scientific article published on 01 March 2001

Computational analysis of the human HSPH/HSPA/DNAJ family and cloning of a human HSPH/HSPA/DNAJ expression library

artículo científico publicado en 2008

Correlation between slowly repairable double-strand breaks and thermal radiosensitization in the human HeLa S3 cell line

artículo científico publicado el 1 de septiembre de 1997

Cytokine treatment improves parenchymal and vascular damage of salivary glands after irradiation

artículo científico publicado en 2008

Cytotoxicity of artemisinin-related endoperoxides to Ehrlich ascites tumor cells.

artículo científico publicado en 1993

Cytotoxicity of flavonoids and sesquiterpene lactones from Arnica species against the GLC4 and the COLO 320 cell lines.

artículo científico publicado en 1994

DNA damage induction and tumour cell radiosensitivity: PFGE and halo measurements

artículo científico publicado el 1 de mayo de 1998

DNA double strand breaks do not play a role in heat-induced cell killing

artículo científico publicado en 2005

DNA polymerase activity in heat killing and hyperthermic radiosensitization of mammalian cells as observed after fractionated heat treatments

artículo científico publicado en 1986

DNAJ Proteins and Protein Aggregation Diseases

artículo científico publicado el 1 de enero de 2012

DNAJB6 is a peptide-binding chaperone which can suppress amyloid fibrillation of polyglutamine peptides at substoichiometric molar ratios.

scientific article published on August 2013

DNAJs: more than substrate delivery to HSPA

artículo científico publicado en 2015

De novo CoA biosynthesis is required to maintain DNA integrity during development of the Drosophila nervous system.

artículo científico publicado en 2008

Deficiency of hepatocystin induces autophagy through an mTOR-dependent pathway

artículo científico publicado en 2011

Differences in heat-induced cell killing as determined in three mammalian cell lines do not correspond with the extent of heat radiosensitization

artículo científico publicado en 1986

Different anti-aggregation and pro-degradative functions of the members of the mammalian sHSP family in neurological disorders.

artículo científico

Distinguishing aggregate formation and aggregate clearance using cell-based assays

artículo científico publicado en 2016

Dynamic changes in the localization of thermally unfolded nuclear proteins associated with chaperone-dependent protection

artículo científico publicado en 2001

Dysfunctional BRCA1 is only indirectly linked to multiple centrosomes.

artículo científico publicado en 2005

ERCC1, hRad51, and BRCA1 protein expression in relation to tumour response and survival of stage III/IV NSCLC patients treated with chemotherapy

article

Early to late sparing of radiation damage to the parotid gland by adrenergic and muscarinic receptor agonists

artículo científico publicado en 2001

Effect of hyperthermia on DNA loop-size in HeLa S3 cells.

artículo científico publicado en 1988

Effects of different small HSPB members on contractile dysfunction and structural changes in a Drosophila melanogaster model for Atrial Fibrillation

artículo científico publicado en 2011

Elevated mutant dynorphin A causes Purkinje cell loss and motor dysfunction in spinocerebellar ataxia type 23.

artículo científico publicado en 2015

Enhanced proliferation of acinar and progenitor cells by prophylactic pilocarpine treatment underlies the observed amelioration of radiation injury to parotid glands.

artículo científico publicado en 2009

Feasibility of measuring radiation-induced DNA double strand breaks and their repair by pulsed field gel electrophoresis in freshly isolated cells from the mouse RIF-1 tumor

artículo científico publicado en 1996

Function, evolution, and structure of J-domain proteins

scientific article published on 26 November 2018

Functional diversity between HSP70 paralogs due to variable interactions with specific co-chaperones

scientific article published on 13 April 2020

Grp/DChk1 is required for G2-M checkpoint activation in Drosophila S2 cells, whereas Dmnk/DChk2 is dispensable

artículo científico publicado en 2005

Guidelines for the nomenclature of the human heat shock proteins

artículo científico publicado en 2009

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

HSP DNAJB8 controls tumor-initiating ability in renal cancer stem-like cells.

artículo científico publicado en 2012

HSPA1A-independent suppression of PARK2 C289G protein aggregation by human small heat shock proteins

artículo científico publicado en 2014

HSPB1, HSPB6, HSPB7 and HSPB8 protect against RhoA GTPase-induced remodeling in tachypaced atrial myocytes

artículo científico publicado en 2011

HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones

artículo científico publicado el 15 de septiembre de 2010

HSPBs: Small proteins with big implications in human disease

artículo científico publicado el 19 de junio de 2012

Heat shock protein (Hsp) 40 mutants inhibit Hsp70 in mammalian cells

artículo científico publicado en 1999

Heat shock protein 70 (Hsp70) stimulates proliferation and cytolytic activity of natural killer cells

artículo científico publicado en 1999

Heat shock protein upregulation protects against pacing-induced myolysis in HL-1 atrial myocytes and in human atrial fibrillation

artículo científico publicado en 2006

Heat shock proteins and Bcl-2 expression and function in relation to the differential hyperthermic sensitivity between leukemic and normal hematopoietic cells

artículo científico publicado en 2007

Heat shock proteins as potential targets for protective strategies in neurodegeneration

artículo científico publicado en 2016

Heat-induced intranuclear protein aggregation and thermal radiosensitization

scientific article published on 01 February 1995

Heat-shock treatment selectively affects induction and repair of cyclobutane pyrimidine dimers in transcriptionally active genes in ultraviolet-irradiated human fibroblasts

scientific article published on 01 September 1993

Hsp70 and Hsp40 Chaperone Activities in the Cytoplasm and the Nucleus of Mammalian Cells

artículo científico publicado el 26 de diciembre de 1997

Hsp70 protects mitotic cells against heat-induced centrosome damage and division abnormalities

artículo científico publicado en 2005

HspB8 participates in protein quality control by a non-chaperone-like mechanism that requires eIF2{alpha} phosphorylation

artículo científico publicado en 2008

Hydroximic acid derivatives: pleiotropic HSP co-inducers restoring homeostasis and robustness.

artículo científico

Hyperthermia, thermotolerance and topoisomerase II inhibitors

artículo científico publicado el 1 de agosto de 1995

Hyperthermic radiosensitization: mode of action and clinical relevance

artículo científico publicado en 2001

Identification of the Drosophila ortholog of HSPB8: implication of HSPB8 loss of function in protein folding diseases.

artículo científico publicado en 2010

In response to Drs. Anscher and Kong

scientific article published on 01 September 2005

Induction of heat shock response protects the heart against atrial fibrillation.

artículo científico publicado en 2006

Interaction between the cytostatic effects of quercetin and 5-fluorouracil in two human colorectal cancer cell lines

artículo científico publicado en 1994

Interaction of hyperthermia and radiation in tolerant and nontolerant HeLa S3 cells: role of DNA polymerase inactivation

artículo científico publicado en 1989

Interaction of the molecular chaperone DNAJB6 with growing amyloid-beta 42 (Aβ42) aggregates leads to sub-stoichiometric inhibition of amyloid formation

artículo científico publicado en 2014

Intravital correlated microscopy reveals differential macrophage and microglial dynamics during resolution of neuroinflammation

artículo científico publicado en 2014

Kadota Fund International Forum 2004. Application of thermal stress for the improvement of health, 15-18 June 2004, Awaji Yumebutai International Conference Center, Awaji Island, Hyogo, Japan. Final report.

artículo científico publicado en 2008

Keratinocyte growth factor prevents radiation damage to salivary glands by expansion of the stem/progenitor pool

artículo científico publicado en 2008

Levels of DNAJB family members (HSP40) correlate with disease onset in patients with spinocerebellar ataxia type 3.

artículo científico publicado en 2010

Loco-regional differences in pulmonary function and density after partial rat lung irradiation.

artículo científico publicado en 2003

Measurement of Chaperone-Mediated Effects on Polyglutamine Protein Aggregation by the Filter Trap Assay

artículo científico publicado en 2018

Mechanism of hyperthermic potentiation of cisplatin action in cisplatin-sensitive and -resistant tumour cells.

artículo científico publicado en 1997

Mobilization of bone marrow stem cells by granulocyte colony-stimulating factor ameliorates radiation-induced damage to salivary glands

artículo científico publicado en 2006

Modulation of polyglutamine inclusion formation by the Hsp70 chaperone machine.

artículo científico publicado en 2007

Molecular biology: It takes two to untangle

artículo científico publicado en 2015

Molecular mechanisms of remodeling in human atrial fibrillation.

artículo científico publicado en 2002

Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers.

artículo científico publicado en 2012

Mutations in potassium channel kcnd3 cause spinocerebellar ataxia type 19.

artículo científico publicado en 2012

Optimum dose range for the amelioration of long term radiation-induced hyposalivation using prophylactic pilocarpine treatment.

artículo científico publicado en 2007

Overexpression of cystathionine γ-lyase suppresses detrimental effects of spinocerebellar ataxia type 3.

artículo científico publicado en 2015

Overexpression of the cochaperone CHIP enhances Hsp70-dependent folding activity in mammalian cells.

artículo científico publicado en 2003

Peripheral blood stem cells differ from bone marrow stem cells in cell cycle status, repopulating potential, and sensitivity toward hyperthermic purging in mice mobilized with cyclophosphamide and granulocyte colony-stimulating factor.

artículo científico publicado en 2002

Polarised asymmetric inheritance of accumulated protein damage in higher eukaryotes

artículo científico publicado en 2006

Polyglutamine aggregation in Huntington's disease and spinocerebellar ataxia type 3: similar mechanisms in aggregate formation

artículo científico publicado en 2015

Post-irradiation dietary vitamin E does not affect the development of radiation-induced lung damage in rats.

artículo científico publicado en 2004

Preservation of the rat parotid gland function after radiation by prophylactic pilocarpine treatment: radiation dose dependency and compensatory mechanisms

artículo científico publicado en 1999

Protection of salivary function by concomitant pilocarpine during radiotherapy: a double-blind, randomized, placebo-controlled study

artículo científico publicado en 2007

Protein refolding in peroxisomes is dependent upon an HSF1-regulated function.

artículo científico publicado en 2012

Purging of acute myeloid leukaemia cells from stem cell grafts by hyperthermia: enhancement of the therapeutic index by the tetrapeptide AcSDKP and the alkyl-lysophospholipid ET-18-OCH(3)

artículo científico publicado en 2000

Quantification of transforming growth factor-beta in biological material using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

artículo científico publicado en 1997

Radiation and transforming growth factor-beta cooperate in transcriptional activation of the profibrotic plasminogen activator inhibitor-1 gene.

artículo científico publicado en 2005

Radiation damage to the heart enhances early radiation-induced lung function loss.

artículo científico publicado en 2005

Radiation induced DNA damage and damage repair in three human tumour cell lines

scientific article published on 01 January 1996

Reconstitution of active telomerase in primary human foreskin fibroblasts: effects on proliferative characteristics and response to ionizing radiation.

artículo científico publicado en 2004

Reduction of cellular cisplatin resistance by hyperthermia—a review

artículo científico publicado el 1 de septiembre de 1997

Regulation of stress-induced intracellular sorting and chaperone function of Hsp27 (HspB1) in mammalian cells.

artículo científico publicado en 2007

Relation between radiation-induced whole lung functional loss and regional structural changes in partial irradiated rat lung.

artículo científico publicado en 2006

Renal expression of heat shock proteins after brain death induction in rats.

artículo científico publicado en 2005

Repair of UV-induced pyrimidine(6-4)pyrimidone photoproducts is selectively inhibited in transcriptionally active genes after heat treatment of human fibroblasts

artículo científico publicado en 1995

Rescue of salivary gland function after stem cell transplantation in irradiated glands

artículo científico publicado en 2008

Rescue of αB Crystallin (HSPB5) Mutants Associated Protein Aggregation by Co-Expression of HSPB5 Partners

artículo científico publicado en 2015

Resistance to heat radiosensitization and protein damage in thermotolerant and thermoresistant cells

artículo científico publicado en 1997

RhoA Activation Sensitizes Cells to Proteotoxic Stimuli by Abrogating the HSF1-Dependent Heat Shock Response

artículo científico publicado en 2015

Role of DNA-PK subunits in radiosensitization by hyperthermia

artículo científico publicado en 1999

Role of lipid peroxidation and DNA damage in paraquat toxicity and the interaction of paraquat with ionizing radiation

artículo científico publicado el 18 de febrero de 1992

SCA14 mutation V138E leads to partly unfolded PKCγ associated with an exposed C-terminus, altered kinetics, phosphorylation and enhanced insolubilization

artículo científico publicado en 2013

Sensitization to cisplatin action by step-down heating in cDDP-sensitive and -resistant cells.

artículo científico publicado en 1995

Sensitizing for cis-diamminedichloroplatinum(II) action by hyperthermia in resistant cells

artículo científico publicado en 1993

Significance of plasma transforming growth factor-beta levels in radiotherapy for non-small-cell lung cancer

artículo científico publicado en 2004

Small heat shock proteins, protein degradation and protein aggregation diseases.

artículo científico publicado en 2011

Specific protein homeostatic functions of small heat-shock proteins increase lifespan.

artículo científico publicado en 2015

Spinocerebellar ataxia type 19/22 mutations alter heterocomplex Kv4.3 channel function and gating in a dominant manner

artículo científico publicado en 2015

Strand break repair, DNA polymerase activity and heat radiosensitization in thermotolerant cells

artículo científico publicado en 1985

Stress at the Korean Mountains: meeting report of the 8th International Workshop on the Molecular Biology of Stress Responses

artículo científico publicado el 2 de octubre de 2010

Structural and functional diversities between members of the human HSPB, HSPH, HSPA, and DNAJ chaperone families.

artículo científico publicado en 2008

Stwl modifies chromatin compaction and is required to maintain DNA integrity in the presence of perturbed DNA replication.

artículo científico publicado en 2008

Synergistic action of calcium-ionophores and hyperthermia is best interpreted as thermal enhancement of calcium toxicity

scientific article published on 01 June 1993

The Copper Metabolism MURR1 domain protein 1 (COMMD1) modulates the aggregation of misfolded protein species in a client-specific manner

artículo científico publicado en 2014

The DNAJB6 and DNAJB8 Protein Chaperones Prevent Intracellular Aggregation of Polyglutamine Peptides

artículo científico publicado el 23 de abril de 2013

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

artículo científico publicado en 2010

The HSPB8-BAG3 chaperone complex is upregulated in astrocytes in the human brain affected by protein aggregation diseases.

artículo científico publicado en 2012

The N terminus of the small heat shock protein HSPB7 drives its polyQ aggregation-suppressing activity

scientific article published on 16 May 2019

The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model.

artículo científico publicado en 2016

The growing world of small heat shock proteins: from structure to functions

artículo científico publicado en 2017

The impact of heart irradiation on dose-volume effects in the rat lung

artículo científico publicado en 2007

The regulation of the autophagic network and its implications for human disease

artículo científico publicado en 2013

The small heat shock proteins family: The long forgotten chaperones

artículo científico publicado el 18 de marzo de 2012

Thermal protein denaturation and protein aggregation in cells made thermotolerant by various chemicals: role of heat shock proteins

scientific article published on 01 August 1995

Thermostability of a nuclear-targeted luciferase expressed in mammalian cells. Destabilizing influence of the intranuclear microenvironment

artículo científico publicado en 1995

Thermotolerance and nuclear protein aggregation: protection against initial damage or better recovery?

scientific article published on 01 September 1995

Transforming growth factor-beta plasma dynamics and post-irradiation lung injury in lung cancer patients.

artículo científico publicado en 2004

Versatile members of the DNAJ family show Hsp70 dependent anti-aggregation activity on RING1 mutant parkin C289G.

artículo científico publicado en 2016

ΔNp73 enhances promoter activity of TGF-β induced genes

artículo científico publicado en 2012

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016