Lista de obras - Jörg Kobarg - Dominio Público Uruguay

"Stop Ne(c)king around": How interactomics contributes to functionally characterize Nek family kinases

artículo científico publicado en 2014

A draft of the human septin interactome

artículo científico publicado en 2010

A spectroscopic analysis of the interaction between the human regulatory proteins RACK1 and Ki-1/57

artículo científico publicado en 2006

A zinc metalloproteinase is responsible for the release of CD30 on human tumor cell lines

artículo científico publicado en 1995

Analysis of the structural determinants for RNA binding of the human protein AUF1/hnRNP D.

artículo científico publicado en 2002

Analysis of the tyrosine phosphorylation and calcium fluxing of human CD6 isoforms with different cytoplasmatic domains.

artículo científico publicado en 1997

Arginine methylation analysis of the splicing-associated SR protein SFRS9/SRP30C.

artículo científico publicado en 2009

CGI-55 interacts with nuclear proteins and co-localizes to p80-coilin positive-coiled bodies in the nucleus

artículo científico publicado en 2006

Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3

artículo científico publicado en 2003

Characterization of hNek6 interactome reveals an important role for its short N-terminal domain and colocalization with proteins at the centrosome

artículo científico publicado en 2010

Characterization of mouse ALCAM (CD166): the CD6-binding domain is conserved in different homologs and mediates cross-species binding

artículo científico publicado en 1997

Characterization of the human NEK7 interactome suggests catalytic and regulatory properties distinct from those of NEK6

artículo científico publicado en 2014

Characterization, mapping and partial cDNA sequence of the 57-kD intracellular Ki-1 antigen.

artículo científico publicado en 1997

Checking NEKs: Overcoming a Bottleneck in Human Diseases

scientific article published on 13 April 2020

Clonal analysis of a human antibody response. III. Nucleotide sequences of monoclonal IgM, IgG, and IgA to rabies virus reveal restricted V kappa gene utilization, junctional V kappa J kappa and V lambda J lambda diversity, and somatic hypermutation ⬇️

artículo científico publicado el 15 de septiembre de 1998

Crystallization and preliminary X-ray study of β-mannosidase fromTrichoderma reesei

scientific article published on 01 March 2000

Defeating Bacterial Resistance and Preventing Mammalian Cells Toxicity Through Rational Design of Antibiotic-Functionalized Nanoparticles.

artículo científico publicado en 2017

Detection and possible prognostic relevance of p53 gene mutations in diffuse large B-cell lymphoma. An analysis of 51 cases and review of the literature.

artículo científico publicado en 2004

Evidence for the association of the human regulatory protein Ki-1/57 with the translational machinery.

artículo científico publicado en 2011

Expression of deletion mutants of the hepatitis B virus protein HBx in E. coli and characterization of their RNA binding activities.

artículo científico publicado en 2001

Expression of the NEK family in normal and cancer tissue: an immunohistochemical study

artículo científico publicado en 2020

FEZ1 interacts with CLASP2 and NEK1 through coiled-coil regions and their cellular colocalization suggests centrosomal functions and regulation by PKC.

artículo científico publicado en 2009

FEZ2 has acquired additional protein interaction partners relative to FEZ1: functional and evolutionary implications

artículo científico publicado en 2011

Fasciculation and elongation zeta proteins 1 and 2: From structural flexibility to functional diversity

artículo científico publicado en 2019

Fasciculation and elongation zeta-1 protein (FEZ1) interacts with the retinoic acid receptor and participates in transcriptional regulation of the Hoxb4 gene

artículo científico publicado en 2017

From protein interaction profile to functional assignment: the human protein Ki-1/57 is associated with pre-mRNA splicing events

scientific article published on 09 May 2010

Functionalized Silica Nanoparticles As an Alternative Platform for Targeted Drug-Delivery of Water Insoluble Drugs.

artículo científico publicado en 2016

Genetic analysis of the maternally induced affinity enhancement in the non-Ox1 idiotypic antibody repertoire of the primary immune response to 2-phenyloxazolone.

artículo científico publicado en 1999

Human FEZ1 has characteristics of a natively unfolded protein and dimerizes in solution

artículo científico publicado en 2009

Human FEZ1 protein forms a disulfide bond mediated dimer: implications for cargo transport.

artículo científico publicado en 2010

Human Nek6 is a monomeric mostly globular kinase with an unfolded short N-terminal domain.

artículo científico publicado en 2011

Human Nek7-interactor RGS2 is required for mitotic spindle organization

artículo científico publicado en 2015

Human Regulatory Protein Ki-1/57 Is a Target of SUMOylation and Affects PML Nuclear Body Formation.

artículo científico publicado en 2017

Human hnRNP Q re-localizes to cytoplasmic granules upon PMA, thapsigargin, arsenite and heat-shock treatments

artículo científico publicado en 2009

Human stanniocalcin-1 interacts with nuclear and cytoplasmic proteins and acts as a SUMO E3 ligase

artículo científico publicado en 2011

IIS--Integrated Interactome System: a web-based platform for the annotation, analysis and visualization of protein-metabolite-gene-drug interactions by integrating a variety of data sources and tools

artículo científico publicado en 2014

Identification and Characterization of an Alternatively Spliced Isoform of the Human Protein Phosphatase 2Aα Catalytic Subunit ⬇️

artículo científico publicado el 13 de diciembre de 2011

Identification and characterization of proteins that selectively interact with isoforms of the mRNA binding protein AUF1 (hnRNP D)

artículo científico publicado en 2003

Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1

artículo científico publicado en 2003

Insights into the full-length SRPK2 structure and its hydrodynamic behavior

scientific article published on 20 June 2019

Ki-1/57 and CGI-55 ectopic expression impact cellular pathways involved in proliferation and stress response regulation

artículo científico publicado en 2014

Ki-1/57 interacts with PRMT1 and is a substrate for arginine methylation

artículo científico publicado en 2006

Kinase inhibitor profile for human nek1, nek6, and nek7 and analysis of the structural basis for inhibitor specificity.

artículo científico publicado en 2015

Low-resolution structural studies of human Stanniocalcin-1

artículo científico publicado en 2009

NEK10 interactome and depletion reveal new roles in mitochondria

artículo científico publicado en 2020

NEK5 interacts with LonP1 and its kinase activity is essential for the regulation of mitochondrial functions and mtDNA maintenance

artículo científico publicado en 2021

NEK5 interacts with topoisomerase IIβ and is involved in the DNA damage response induced by etoposide

artículo científico publicado en 2019

Nek5 interacts with mitochondrial proteins and interferes negatively in mitochondrial mediated cell death and respiration.

artículo científico publicado en 2015

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing

artículo científico publicado en 2015

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

artículo científico publicado en 2011

Over-expression of GFP-FEZ1 causes generation of multi-lobulated nuclei mediated by microtubules in HEK293 cells.

artículo científico publicado en 2008

Potential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N-(2-(Piperidin-1-yl)-5-(Trifluoromethyl)Phenyl)Isonicotinamide (SRPIN340)

artículo científico publicado en 2015

Proteomic Analysis of the Spatio-temporal Based Molecular Kinetics of Acute Spinal Cord Injury Identifies a Time- and Segment-specific Window for Effective Tissue Repair

artículo científico publicado en 2016

Selective synthesis of silver nanoparticles onto potassium hexaniobate: structural organisation with bactericidal properties.

artículo científico publicado en 2013

Shape Tailored Magnetic Nanorings for Intracellular Hyperthermia Cancer Therapy.

artículo científico publicado en 2017

Shedding of the soluble form of CD30 from the Hodgkin-analogous cell line L540 is strongly inhibited by a new CD30-specific antibody (Ki-4).

artículo científico publicado en 1995

Solution structure of the human signaling protein RACK1.

artículo científico publicado en 2010

Structural analysis of intermolecular interactions in the kinesin adaptor complex fasciculation and elongation protein zeta 1/ short coiled-coil protein (FEZ1/SCOCO)

artículo científico publicado en 2013

Sweeter but deadlier: decoupling size, charge and capping effects in carbohydrate coated bactericidal silver nanoparticles

artículo científico publicado en 2013

Tailored silica-antibiotic nanoparticles: overcoming bacterial resistance with low cytotoxicity

artículo científico publicado en 2014

The CATS (FAM64A) protein is a substrate of the Kinase Interacting Stathmin (KIS).

artículo científico publicado en 2013

The Drosophila melanogaster Eip74EF-PA transcription factor directly binds the sciarid BhC4-1 promoter

artículo científico publicado en 2017

The Isoflavanoid (+)‐PTC Regulates Cell‐Cycle Progression and Mitotic Spindle Assembly in a Prostate Cancer Cell Line

artículo científico publicado en 2022

The acidic domain of hnRNPQ (NSAP1) has structural similarity to Barstar and binds to Apobec1

artículo científico publicado en 2006

The cysteine residues of the hepatitis B virus onco-protein HBx are not required for its interaction with RNA or with human p53.

artículo científico publicado en 2005

The methylation of the C-terminal region of hnRNPQ (NSAP1) is important for its nuclear localization

scientific article published on 01 July 2006

The molecular motor Myosin Va interacts with the cilia-centrosomal protein RPGRIP1L.

artículo científico publicado en 2017

Use of a special Brazilian red-light emitting railroad worm Luciferase in bioassays of NEK7 protein Kinase and Creatine Kinase

artículo científico

Viral Inhibition Mechanism Mediated by Surface-Modified Silica Nanoparticles.

artículo científico publicado en 2016

Lista de obras de Jörg Kobarg

"Stop Ne(c)king around": How interactomics contributes to functionally characterize Nek family kinases

A draft of the human septin interactome

A spectroscopic analysis of the interaction between the human regulatory proteins RACK1 and Ki-1/57

A zinc metalloproteinase is responsible for the release of CD30 on human tumor cell lines

Analysis of the structural determinants for RNA binding of the human protein AUF1/hnRNP D.

Analysis of the tyrosine phosphorylation and calcium fluxing of human CD6 isoforms with different cytoplasmatic domains.

Arginine methylation analysis of the splicing-associated SR protein SFRS9/SRP30C.

CGI-55 interacts with nuclear proteins and co-localizes to p80-coilin positive-coiled bodies in the nucleus

Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3

Characterization of hNek6 interactome reveals an important role for its short N-terminal domain and colocalization with proteins at the centrosome

Characterization of mouse ALCAM (CD166): the CD6-binding domain is conserved in different homologs and mediates cross-species binding

Characterization of the human NEK7 interactome suggests catalytic and regulatory properties distinct from those of NEK6

Characterization, mapping and partial cDNA sequence of the 57-kD intracellular Ki-1 antigen.

Checking NEKs: Overcoming a Bottleneck in Human Diseases

Clonal analysis of a human antibody response. III. Nucleotide sequences of monoclonal IgM, IgG, and IgA to rabies virus reveal restricted V kappa gene utilization, junctional V kappa J kappa and V lambda J lambda diversity, and somatic hypermutation ⬇️

Crystallization and preliminary X-ray study of β-mannosidase fromTrichoderma reesei

Defeating Bacterial Resistance and Preventing Mammalian Cells Toxicity Through Rational Design of Antibiotic-Functionalized Nanoparticles.

Detection and possible prognostic relevance of p53 gene mutations in diffuse large B-cell lymphoma. An analysis of 51 cases and review of the literature.

Evidence for the association of the human regulatory protein Ki-1/57 with the translational machinery.

Expression of deletion mutants of the hepatitis B virus protein HBx in E. coli and characterization of their RNA binding activities.

Expression of the NEK family in normal and cancer tissue: an immunohistochemical study

FEZ1 interacts with CLASP2 and NEK1 through coiled-coil regions and their cellular colocalization suggests centrosomal functions and regulation by PKC.

FEZ2 has acquired additional protein interaction partners relative to FEZ1: functional and evolutionary implications

Fasciculation and elongation zeta proteins 1 and 2: From structural flexibility to functional diversity

Fasciculation and elongation zeta-1 protein (FEZ1) interacts with the retinoic acid receptor and participates in transcriptional regulation of the Hoxb4 gene

From protein interaction profile to functional assignment: the human protein Ki-1/57 is associated with pre-mRNA splicing events

Functionalized Silica Nanoparticles As an Alternative Platform for Targeted Drug-Delivery of Water Insoluble Drugs.

Genetic analysis of the maternally induced affinity enhancement in the non-Ox1 idiotypic antibody repertoire of the primary immune response to 2-phenyloxazolone.

Human FEZ1 has characteristics of a natively unfolded protein and dimerizes in solution

Human FEZ1 protein forms a disulfide bond mediated dimer: implications for cargo transport.

Human Nek6 is a monomeric mostly globular kinase with an unfolded short N-terminal domain.

Human Nek7-interactor RGS2 is required for mitotic spindle organization

Human Regulatory Protein Ki-1/57 Is a Target of SUMOylation and Affects PML Nuclear Body Formation.

Human hnRNP Q re-localizes to cytoplasmic granules upon PMA, thapsigargin, arsenite and heat-shock treatments

Human stanniocalcin-1 interacts with nuclear and cytoplasmic proteins and acts as a SUMO E3 ligase

IIS--Integrated Interactome System: a web-based platform for the annotation, analysis and visualization of protein-metabolite-gene-drug interactions by integrating a variety of data sources and tools

Identification and Characterization of an Alternatively Spliced Isoform of the Human Protein Phosphatase 2Aα Catalytic Subunit ⬇️

Identification and characterization of proteins that selectively interact with isoforms of the mRNA binding protein AUF1 (hnRNP D)

Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1

Insights into the full-length SRPK2 structure and its hydrodynamic behavior

Ki-1/57 and CGI-55 ectopic expression impact cellular pathways involved in proliferation and stress response regulation

Ki-1/57 interacts with PRMT1 and is a substrate for arginine methylation

Kinase inhibitor profile for human nek1, nek6, and nek7 and analysis of the structural basis for inhibitor specificity.

Low-resolution structural studies of human Stanniocalcin-1

NEK10 interactome and depletion reveal new roles in mitochondria

NEK5 interacts with LonP1 and its kinase activity is essential for the regulation of mitochondrial functions and mtDNA maintenance

NEK5 interacts with topoisomerase IIβ and is involved in the DNA damage response induced by etoposide

Nek5 interacts with mitochondrial proteins and interferes negatively in mitochondrial mediated cell death and respiration.

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

Over-expression of GFP-FEZ1 causes generation of multi-lobulated nuclei mediated by microtubules in HEK293 cells.

Potential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N-(2-(Piperidin-1-yl)-5-(Trifluoromethyl)Phenyl)Isonicotinamide (SRPIN340)

Proteomic Analysis of the Spatio-temporal Based Molecular Kinetics of Acute Spinal Cord Injury Identifies a Time- and Segment-specific Window for Effective Tissue Repair

Selective synthesis of silver nanoparticles onto potassium hexaniobate: structural organisation with bactericidal properties.

Shape Tailored Magnetic Nanorings for Intracellular Hyperthermia Cancer Therapy.

Shedding of the soluble form of CD30 from the Hodgkin-analogous cell line L540 is strongly inhibited by a new CD30-specific antibody (Ki-4).

Solution structure of the human signaling protein RACK1.

Structural analysis of intermolecular interactions in the kinesin adaptor complex fasciculation and elongation protein zeta 1/ short coiled-coil protein (FEZ1/SCOCO)

Sweeter but deadlier: decoupling size, charge and capping effects in carbohydrate coated bactericidal silver nanoparticles

Tailored silica-antibiotic nanoparticles: overcoming bacterial resistance with low cytotoxicity

The CATS (FAM64A) protein is a substrate of the Kinase Interacting Stathmin (KIS).

The Drosophila melanogaster Eip74EF-PA transcription factor directly binds the sciarid BhC4-1 promoter

The Isoflavanoid (+)‐PTC Regulates Cell‐Cycle Progression and Mitotic Spindle Assembly in a Prostate Cancer Cell Line

The acidic domain of hnRNPQ (NSAP1) has structural similarity to Barstar and binds to Apobec1

The cysteine residues of the hepatitis B virus onco-protein HBx are not required for its interaction with RNA or with human p53.

The methylation of the C-terminal region of hnRNPQ (NSAP1) is important for its nuclear localization

The molecular motor Myosin Va interacts with the cilia-centrosomal protein RPGRIP1L.

Use of a special Brazilian red-light emitting railroad worm Luciferase in bioassays of NEK7 protein Kinase and Creatine Kinase

Viral Inhibition Mechanism Mediated by Surface-Modified Silica Nanoparticles.