Lista de obras - Mohamed-Ali Hakimi - Dominio Público Uruguay

A Critical Role for Toxoplasma gondii Vacuolar Protein Sorting VPS9 in Secretory Organelle Biogenesis and Host Infection

artículo científico publicado en 2016

A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment

artículo científico publicado en 2020

A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation.

artículo científico publicado en 2013

A brain cyst load-associated antigen is a Toxoplasma gondii biomarker for serodetection of persistent parasites and chronic infection

artículo científico publicado en 2021

A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes

artículo científico publicado en 2003

A chromatin remodelling complex that loads cohesin onto human chromosomes

artículo científico publicado en 2002

A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes

artículo científico publicado en 2002

Activity of the histone deacetylase inhibitor FR235222 on Toxoplasma gondii: inhibition of stage conversion of the parasite cyst form and study of new derivative compounds

artículo científico publicado en 2010

Apicomplexan parasites and subversion of the host cell microRNA pathway ⬇️

artículo científico publicado el 15 de agosto de 2011

Argonaute quenching and global changes in Dicer homeostasis caused by a pathogen-encoded GW repeat protein.

artículo científico publicado en 2010

Assembly of the novel five-component apicomplexan multi-aminoacyl-tRNA synthetase complex is driven by the hybrid scaffold protein Tg-p43

artículo científico publicado en 2014

Characterization of a effector uncovers an alternative GSK3/β-catenin-regulatory pathway of inflammation

artículo científico publicado en 2018

Chromatin modifications: implications in the regulation of gene expression in Toxoplasma gondii.

artículo científico publicado en 2010

Cryptosporidium and Toxoplasma Parasites Are Inhibited by a Benzoxaborole Targeting Leucyl-tRNA Synthetase

artículo científico publicado en 2016

Do apicomplexan parasites hijack the host cell microRNA pathway for their intracellular development?

artículo científico publicado en 2010

Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development

artículo científico publicado en 2022

Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites

scientific article published on 06 April 2009

Epigenetic mechanisms regulate stage differentiation in the minimized protozoan Giardia lamblia

artículo científico publicado en 2010

Evidence for ARGONAUTE4-DNA interactions in RNA-directed DNA methylation in plants.

artículo científico publicado en 2016

Evolutionary conservation of C-terminal domains of primary sigma(70)-type transcription factors between plants and bacteria

artículo científico publicado en 2000

Fission yeast homologs of human histone H3 lysine 4 demethylase regulate a common set of genes with diverse functions

scientific article published on 21 September 2006

Flexible synthesis and evaluation of diverse anti-Apicomplexa cyclic peptides.

artículo científico publicado en 2013

Functional interplay between histone demethylase and deacetylase enzymes

artículo científico

Host cell subversion by Toxoplasma GRA16, an exported dense granule protein that targets the host cell nucleus and alters gene expression.

artículo científico publicado en 2013

Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II

artículo científico publicado en 2005

Intraplastidial trafficking of a phage-type RNA polymerase is mediated by a thylakoid RING-H2 protein

artículo científico publicado en 2008

Linking transcriptional elongation and messenger RNA export to metastatic breast cancers

artículo científico publicado en 2005

Lysine acetyltransferase GCN5b interacts with AP2 factors and is required for Toxoplasma gondii proliferation

artículo científico publicado en 2014

Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection

scientific article published on 01 November 2019

Modifications at K31 on the lateral surface of histone H4 contribute to genome structure and expression in apicomplexan parasites.

artículo científico publicado en 2017

Recombinant expression, purification, and crystallization of the glutaminyl-tRNA synthetase from Toxoplasma gondii

artículo científico

Recruitment of MLL by HMG-domain protein iBRAF promotes neural differentiation.

artículo científico publicado en 2005

Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair

artículo científico publicado en 2003

Reinforcement of silencing at transposons and highly repeated sequences requires the concerted action of two distinct RNA polymerases IV in Arabidopsis.

artículo científico publicado en 2005

Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components.

artículo científico publicado en 2007

SET8-mediated methylations of histone H4 lysine 20 mark silent heterochromatic domains in apicomplexan genomes.

artículo científico publicado en 2007

Structural Basis for the Subversion of MAP Kinase Signaling by an Intrinsically Disordered Parasite Secreted Agonist

artículo científico publicado en 2016

Structure of Prolyl-tRNA Synthetase-Halofuginone Complex Provides Basis for Development of Drugs against Malaria and Toxoplasmosis

artículo científico publicado en 2015

Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis

artículo científico publicado en 2017

Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis

artículo científico publicado en 2017

The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole.

artículo científico publicado en 2015

The Toxoplasma effector TEEGR promotes parasite persistence by modulating NF-κB signalling via EZH2

scientific article published on 29 April 2019

The aspartyl protease TgASP5 mediates the export of the Toxoplasma GRA16 and GRA24 effectors into host cells

artículo científico publicado en 2015

The histone methylase KMTox interacts with the redox-sensor peroxiredoxin-1 and targets genes involved in Toxoplasma gondii antioxidant defences

artículo científico publicado en 2008

The motor protein kinesin-1 links neurofibromin and merlin in a common cellular pathway of neurofibromatosis

artículo científico publicado en 2002

Toxoplasma GRA15 limits parasite growth in IFNγ-activated fibroblasts through TRAF ubiquitin ligases

scientific article published on 15 April 2020

Toxoplasma exports dense granule proteins beyond the vacuole to the host cell nucleus and rewires the host genome expression.

artículo científico publicado en 2014

Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-γ-mediated host defenses.

artículo científico publicado en 2016

Toxoplasma gondii gene expression is under the control of regulatory pathways acting through chromatin structure.

artículo científico publicado en 2008

Toxoplasma gondii peroxiredoxin promotes altered macrophage function, caspase-1-dependent IL-1β secretion enhances parasite replication ⬇️

artículo científico publicado el 27 de junio de 2011

Toxoplasma's ways of manipulating the host transcriptome via secreted effectors.

artículo científico

Transcription factor IIB (TFIIB)-related protein (pBrp), a plant-specific member of the TFIIB-related protein family.

artículo científico publicado en 2003

UAP56 associates with DRM2 and is localized to chromatin in Arabidopsis

scientific article published on 05 April 2019

Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection

artículo científico publicado en 2016

miR-146a and miR-155 delineate a MicroRNA fingerprint associated with Toxoplasma persistence in the host brain.

artículo científico publicado en 2014

Lista de obras de Mohamed-Ali Hakimi

A Critical Role for Toxoplasma gondii Vacuolar Protein Sorting VPS9 in Secretory Organelle Biogenesis and Host Infection

A MORC-driven transcriptional switch controls Toxoplasma developmental trajectories and sexual commitment

A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation.

A brain cyst load-associated antigen is a Toxoplasma gondii biomarker for serodetection of persistent parasites and chronic infection

A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes

A chromatin remodelling complex that loads cohesin onto human chromosomes

A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes

Activity of the histone deacetylase inhibitor FR235222 on Toxoplasma gondii: inhibition of stage conversion of the parasite cyst form and study of new derivative compounds

Apicomplexan parasites and subversion of the host cell microRNA pathway ⬇️

Argonaute quenching and global changes in Dicer homeostasis caused by a pathogen-encoded GW repeat protein.

Assembly of the novel five-component apicomplexan multi-aminoacyl-tRNA synthetase complex is driven by the hybrid scaffold protein Tg-p43

Characterization of a effector uncovers an alternative GSK3/β-catenin-regulatory pathway of inflammation

Chromatin modifications: implications in the regulation of gene expression in Toxoplasma gondii.

Cryptosporidium and Toxoplasma Parasites Are Inhibited by a Benzoxaborole Targeting Leucyl-tRNA Synthetase

Do apicomplexan parasites hijack the host cell microRNA pathway for their intracellular development?

Double drugging of prolyl-tRNA synthetase provides a new paradigm for anti-infective drug development

Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites

Epigenetic mechanisms regulate stage differentiation in the minimized protozoan Giardia lamblia

Evidence for ARGONAUTE4-DNA interactions in RNA-directed DNA methylation in plants.

Evolutionary conservation of C-terminal domains of primary sigma(70)-type transcription factors between plants and bacteria

Fission yeast homologs of human histone H3 lysine 4 demethylase regulate a common set of genes with diverse functions

Flexible synthesis and evaluation of diverse anti-Apicomplexa cyclic peptides.

Functional interplay between histone demethylase and deacetylase enzymes

Host cell subversion by Toxoplasma GRA16, an exported dense granule protein that targets the host cell nucleus and alters gene expression.

Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II

Intraplastidial trafficking of a phage-type RNA polymerase is mediated by a thylakoid RING-H2 protein

Linking transcriptional elongation and messenger RNA export to metastatic breast cancers

Lysine acetyltransferase GCN5b interacts with AP2 factors and is required for Toxoplasma gondii proliferation

Metal-captured inhibition of pre-mRNA processing activity by CPSF3 controls Cryptosporidium infection

Modifications at K31 on the lateral surface of histone H4 contribute to genome structure and expression in apicomplexan parasites.

Recombinant expression, purification, and crystallization of the glutaminyl-tRNA synthetase from Toxoplasma gondii

Recruitment of MLL by HMG-domain protein iBRAF promotes neural differentiation.

Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair

Reinforcement of silencing at transposons and highly repeated sequences requires the concerted action of two distinct RNA polymerases IV in Arabidopsis.

Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components.

SET8-mediated methylations of histone H4 lysine 20 mark silent heterochromatic domains in apicomplexan genomes.

Structural Basis for the Subversion of MAP Kinase Signaling by an Intrinsically Disordered Parasite Secreted Agonist

Structure of Prolyl-tRNA Synthetase-Halofuginone Complex Provides Basis for Development of Drugs against Malaria and Toxoplasmosis

Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis

Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis

The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole.

The Toxoplasma effector TEEGR promotes parasite persistence by modulating NF-κB signalling via EZH2

The aspartyl protease TgASP5 mediates the export of the Toxoplasma GRA16 and GRA24 effectors into host cells

The histone methylase KMTox interacts with the redox-sensor peroxiredoxin-1 and targets genes involved in Toxoplasma gondii antioxidant defences

The motor protein kinesin-1 links neurofibromin and merlin in a common cellular pathway of neurofibromatosis

Toxoplasma GRA15 limits parasite growth in IFNγ-activated fibroblasts through TRAF ubiquitin ligases

Toxoplasma exports dense granule proteins beyond the vacuole to the host cell nucleus and rewires the host genome expression.

Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-γ-mediated host defenses.

Toxoplasma gondii gene expression is under the control of regulatory pathways acting through chromatin structure.

Toxoplasma gondii peroxiredoxin promotes altered macrophage function, caspase-1-dependent IL-1β secretion enhances parasite replication ⬇️

Toxoplasma's ways of manipulating the host transcriptome via secreted effectors.

Transcription factor IIB (TFIIB)-related protein (pBrp), a plant-specific member of the TFIIB-related protein family.

UAP56 associates with DRM2 and is localized to chromatin in Arabidopsis

Unconventional endosome-like compartment and retromer complex in Toxoplasma gondii govern parasite integrity and host infection

miR-146a and miR-155 delineate a MicroRNA fingerprint associated with Toxoplasma persistence in the host brain.