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Lista de obras de Paul C Guest

A combined metabonomic and proteomic approach identifies frontal cortex changes in a chronic phencyclidine rat model in relation to human schizophrenia brain pathology

artículo científico publicado en 2013

Abnormalities in metabolism and hypothalamic-pituitary-adrenal axis function in schizophrenia

artículo científico

Algorithm development for diagnostic biomarker assays

artículo científico

Alterations of stress related proteins in genetically altered mice revealed by two-dimensional differential in-gel electrophoresis analysis

artículo científico publicado en 2002

Altered levels of circulating insulin and other neuroendocrine hormones associated with the onset of schizophrenia.

artículo científico publicado en 2011

Analysis of serum and plasma identifies differences in molecular coverage, measurement variability, and candidate biomarker selection

article

Analysis of the human pituitary proteome by data independent label-free liquid chromatography tandem mass spectrometry

artículo científico publicado en 2011

Analysis of the rat hypothalamus proteome by data-independent label-free LC-MS/MS.

artículo científico publicado en 2012

Antipsychotic treatment of acute paranoid schizophrenia patients with olanzapine results in altered glycosylation of serum glycoproteins.

artículo científico publicado en 2012

Application of Proteomic Techniques for Improved Stratification and Treatment of Schizophrenia Patients

artículo científico publicado en 2017

Application of meta-analysis methods for identifying proteomic expression level differences.

artículo científico publicado en 2013

Applications of blood-based protein biomarker strategies in the study of psychiatric disorders

artículo científico publicado en 2014

Behavioral and molecular biomarkers in translational animal models for neuropsychiatric disorders

artículo científico publicado en 2011

Biomarker discovery in human cerebrospinal fluid: the need for integrative metabolome and proteome databases

artículo científico publicado en 2012

Blood test for schizophrenia

artículo científico publicado el 26 de agosto de 2012

Challenges in drug target discovery in bipolar disorder.

artículo científico

Challenges of introducing new biomarker products for neuropsychiatric disorders into the market

artículo científico

Characterization of the human primary visual cortex and cerebellum proteomes using shotgun mass spectrometry-data-independent analyses

artículo científico publicado en 2012

Characterization of the human serum depletome by label-free shotgun proteomics

artículo científico publicado en 2011

Characterizing the proteome of the human dorsolateral prefrontal cortex by shotgun mass spectrometry

artículo científico publicado en 2011

Clinical use of phosphorylated proteins in blood serum analysed by immobilised metal ion affinity chromatography and mass spectrometry.

artículo científico publicado en 2012

Comparison of peripheral and central schizophrenia biomarker profiles

artículo científico publicado en 2012

Comprehensive two-dimensional liquid chromatography mass spectrometric profiling of the rat hippocampal proteome

artículo científico publicado en 2011

Converging evidence of blood-based biomarkers for schizophrenia: an update

artículo científico

Detection of gender differences in rat lens proteins using 2-D-DIGE.

artículo científico publicado en 2006

Development of a novel assay for proprotein converting enzyme activity on a multiplex bead-based array system

artículo científico publicado en 2013

Diabetic db/db mice exhibit central nervous system and peripheral molecular alterations as seen in neurological disorders

artículo científico publicado el 28 de mayo de 2013

Differential phosphorylation of serum proteins reflecting inflammatory changes in schizophrenia patients

artículo científico publicado en 2011

Distinct molecular phenotypes in male and female schizophrenia patients

artículo científico publicado en 2013

Distinct proteomic profiles in post-mortem pituitary glands from bipolar disorder and major depressive disorder patients

artículo científico publicado en 2014

Disturbed macro-connectivity in schizophrenia linked to oligodendrocyte dysfunction: from structural findings to molecules

artículo científico publicado en 2015

Effect of MK-801 and Clozapine on the Proteome of Cultured Human Oligodendrocytes

artículo científico publicado en 2016

Effects of olanzapine on serum protein phosphorylation patterns in patients with schizophrenia

artículo científico publicado en 2015

Electroconvulsive therapy exerts mainly acute molecular changes in serum of major depressive disorder patients.

artículo científico publicado en 2012

Elevated S100B levels in schizophrenia are associated with insulin resistance

scientific article published on 01 January 2010

Evidence for disease and antipsychotic medication effects in post-mortem brain from schizophrenia patients

article

Glial cells as key players in schizophrenia pathology: recent insights and concepts of therapy

artículo científico publicado en 2014

Identification of N-glycosylation changes in the CSF and serum in patients with schizophrenia

artículo científico publicado en 2010

Identification of a biological signature for schizophrenia in serum

article

Identification of a blood-based biological signature in subjects with psychiatric disorders prior to clinical manifestation

artículo científico publicado en 2011

Identification of a molecular profile associated with immune status in first-onset schizophrenia patients.

artículo científico publicado en 2014

Identification of altered dipeptidyl-peptidase activities as potential biomarkers for unipolar depression

artículo científico publicado en 2013

Identification of an age-dependent biomarker signature in children and adolescents with autism spectrum disorders

artículo científico publicado en 2013

Identification of blood-based molecular signatures for prediction of response and relapse in schizophrenia patients

artículo científico publicado en 2012

Identification of differentiating neural progenitor cell markers using shotgun isobaric tagging mass spectrometry

artículo científico publicado en 2006

Identification of early proteomic markers for hepatic steatosis

scientific article published on 01 August 2006

Identification of proteomic changes during differentiation of adult mouse subventricular zone progenitor cells.

artículo científico publicado en 2007

Identification of proteomic signatures associated with depression and psychotic depression in post-mortem brains from major depression patients

artículo científico publicado el 13 de marzo de 2012

Identification of subgroups of schizophrenia patients with changes in either immune or growth factor and hormonal pathways

artículo científico publicado en 2013

Identification of targeted analyte clusters for studies of schizophrenia

artículo científico publicado en 2009

Impaired glycolytic response in peripheral blood mononuclear cells of first-onset antipsychotic-naive schizophrenia patients

artículo científico publicado en 2010

Integrative proteomic analysis of the NMDA NR1 knockdown mouse model reveals effects on central and peripheral pathways associated with schizophrenia and autism spectrum disorders

artículo científico publicado en 2014

MK-801 treatment affects glycolysis in oligodendrocytes more than in astrocytes and neuronal cells: insights for schizophrenia

artículo científico publicado en 2015

Making Sense of Blood-Based Proteomics and Metabolomics in Psychiatric Research

artículo científico publicado en 2015

Metabolic, hormonal and stress-related molecular changes inpost-mortempituitary glands from schizophrenia subjects

artículo científico publicado el 17 de enero de 2012

Metabonomic studies of schizophrenia and psychotropic medications: focus on alterations in CNS energy homeostasis

scientific article published on December 2009

Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue.

artículo científico publicado en 1993

Molecular sex differences in human serum

artículo científico publicado en 2012

Molecular validation of the acute phencyclidine rat model for schizophrenia: identification of translational changes in energy metabolism and neurotransmission

artículo científico publicado en 2012

Multiplex Biomarker Approaches to Enable Point-of-Care Testing and Personalized Medicine

artículo científico publicado en 2017

Multiplex immunoassay analysis of plasma shows prominent upregulation of growth factor activity pathways linked to GSK3β signaling in bipolar patients

artículo científico publicado en 2013

Multiplex proteomic analysis by two-dimensional differential in-gel electrophoresis.

artículo científico publicado en 2003

Neuroimmune biomarkers in schizophrenia

artículo científico publicado en 2014

Oligomerization of G-protein-coupled receptors shown by selective co-immunoprecipitation

artículo científico publicado en 2002

Peripheral profiling analysis for bipolar disorder reveals markers associated with reduced cell survival.

artículo científico publicado en 2010

Phosphoproteomic differences in major depressive disorder postmortem brains indicate effects on synaptic function

artículo científico publicado en 2012

Proinsulin processing in the diabetic Goto-Kakizaki rat

scientific journal article

Proteomic Approaches to Enable Point-of-Care Testing and Personalized Medicine for Psychiatric Disorders

artículo científico publicado en 2017

Proteomic analysis identifies alterations in cellular morphology and cell death pathways in mouse brain after chronic corticosterone treatment.

artículo científico publicado en 2006

Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration

artículo científico publicado en 2012

Proteomic analysis of post mortem brain tissue from autism patients: evidence for opposite changes in prefrontal cortex and cerebellum in synaptic connectivity-related proteins

artículo científico publicado en 2014

Proteomic analysis of the maternal protein restriction rat model for schizophrenia: identification of translational changes in hormonal signaling pathways and glutamate neurotransmission

artículo científico publicado en 2012

Proteomic approaches to unravel the complexity of schizophrenia

artículo científico

Proteomic changes in serum of first onset, antidepressant drug-naïve major depression patients

artículo científico publicado en 2014

Proteomic changes induced by anaesthesia and muscle relaxant treatment prior to electroconvulsive therapy.

artículo científico publicado en 2011

Proteomic enrichment analysis of psychotic and affective disorders reveals common signatures in presynaptic glutamatergic signaling and energy metabolism

artículo científico publicado en 2014

Proteomic profiling in schizophrenia: enabling stratification for more effective treatment

artículo científico publicado en 2013

Proteomic technologies for biomarker studies in psychiatry: advances and needs

artículo científico

Proteomics: improving biomarker translation to modern medicine?

artículo científico publicado en 2013

Schizophrenia: metabolic aspects of aetiology, diagnosis and future treatment strategies

artículo científico

Serum proteomic analysis identifies sex-specific differences in lipid metabolism and inflammation profiles in adults diagnosed with Asperger syndrome

scientific article published on 27 January 2014

Sex Differences in Serum Markers of Major Depressive Disorder in the Netherlands Study of Depression and Anxiety (NESDA).

artículo científico publicado en 2016

Sex-specific serum biomarker patterns in adults with Asperger's syndrome.

artículo científico publicado en 2010

The Application of Multiplex Biomarker Techniques for Improved Stratification and Treatment of Schizophrenia Patients

artículo científico publicado en 2017

The Application of Multiplexed Assay Systems for Molecular Diagnostics

artículo científico publicado el 1 de enero de 2011

The application of selective reaction monitoring confirms dysregulation of glycolysis in a preclinical model of schizophrenia

artículo científico publicado en 2012

The methylazoxymethanol acetate (MAM-E17) rat model: molecular and functional effects in the hippocampus.

artículo científico publicado en 2011

The need for a comprehensive molecular characterization of autism spectrum disorders

artículo científico publicado en 2013

The role of energy metabolism dysfunction and oxidative stress in schizophrenia revealed by proteomics

artículo científico publicado en 2010

The role of proteomics in depression research

artículo científico publicado en 2009

The use of proteomic biomarkers for improved diagnosis and stratification of schizophrenia patients

artículo científico publicado en 2014

To label or not to label: applications of quantitative proteomics in neuroscience research

artículo científico

Translating potential biomarker candidates for schizophrenia and depression to animal models of psychiatric disorders

artículo científico publicado en 2011