Lista de obras - Noel A Warfel - Dominio Público Uruguay

CDK1 stabilizes HIF-1α via direct phosphorylation of Ser668 to promote tumor growth

artículo científico publicado en 2013

CTGF-mediated autophagy-senescence transition in tumor stroma promotes anabolic tumor growth and metastasis.

artículo científico publicado en 2012

Common polymorphism in the phosphatase PHLPP2 results in reduced regulation of Akt and protein kinase C.

artículo científico publicado en 2009

Disruption of the interface between the pleckstrin homology (PH) and kinase domains of Akt protein is sufficient for hydrophobic motif site phosphorylation in the absence of mTORC2

artículo científico publicado en 2011

HIF-1 signaling in drug resistance to chemotherapy

artículo científico

Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors.

artículo científico publicado en 2007

Importance of the stress kinase p38alpha in mediating the direct cytotoxic effects of the thalidomide analogue, CPS49, in cancer cells and endothelial cells.

artículo científico publicado en 2006

Insulin receptor substrate 1 is a substrate of the Pim protein kinases.

artículo científico publicado en 2016

Mislocalization of the E3 ligase, β-transducin repeat-containing protein 1 (β-TrCP1), in glioblastoma uncouples negative feedback between the pleckstrin homology domain leucine-rich repeat protein phosphatase 1 (PHLPP1) and Akt.

artículo científico publicado en 2011

Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo

artículo científico publicado en 2007

PIM Kinase Inhibitors Kill Hypoxic Tumor Cells by Reducing Nrf2 Signaling and Increasing Reactive Oxygen Species

artículo científico publicado en 2016

PIM kinase (and Akt) biology and signaling in tumors.

artículo científico publicado en 2015

PIM1 phosphorylates ABI2 to enhance actin dynamics and promote tumor invasion

artículo científico publicado en 2023

Phosphatidylinositol ether lipid analogues that inhibit AKT also independently activate the stress kinase, p38alpha, through MKK3/6-independent and -dependent mechanisms.

artículo científico publicado en 2007

Pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP): a new player in cell signaling.

artículo científico publicado en 2011

Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53.

artículo científico publicado en 2015

Strange Bedfellows: Nuclear Factor, Erythroid 2-Like 2 (Nrf2) and Hypoxia-Inducible Factor 1 (HIF-1) in Tumor Hypoxia.

artículo científico publicado en 2017

Targeting CDK4/6 to oppose hypoxia-mediated therapeutic resistance

artículo científico publicado en 2017

The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer

artículo científico publicado en 2021

Lista de obras de Noel A Warfel

CDK1 stabilizes HIF-1α via direct phosphorylation of Ser668 to promote tumor growth

CTGF-mediated autophagy-senescence transition in tumor stroma promotes anabolic tumor growth and metastasis.

Common polymorphism in the phosphatase PHLPP2 results in reduced regulation of Akt and protein kinase C.

Disruption of the interface between the pleckstrin homology (PH) and kinase domains of Akt protein is sufficient for hydrophobic motif site phosphorylation in the absence of mTORC2

HIF-1 signaling in drug resistance to chemotherapy

Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors.

Importance of the stress kinase p38alpha in mediating the direct cytotoxic effects of the thalidomide analogue, CPS49, in cancer cells and endothelial cells.

Insulin receptor substrate 1 is a substrate of the Pim protein kinases.

Mislocalization of the E3 ligase, β-transducin repeat-containing protein 1 (β-TrCP1), in glioblastoma uncouples negative feedback between the pleckstrin homology domain leucine-rich repeat protein phosphatase 1 (PHLPP1) and Akt.

Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that induces endoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo

PIM Kinase Inhibitors Kill Hypoxic Tumor Cells by Reducing Nrf2 Signaling and Increasing Reactive Oxygen Species

PIM kinase (and Akt) biology and signaling in tumors.

PIM1 phosphorylates ABI2 to enhance actin dynamics and promote tumor invasion

Phosphatidylinositol ether lipid analogues that inhibit AKT also independently activate the stress kinase, p38alpha, through MKK3/6-independent and -dependent mechanisms.

Pleckstrin homology domain leucine-rich repeat protein phosphatase (PHLPP): a new player in cell signaling.

Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53.

Strange Bedfellows: Nuclear Factor, Erythroid 2-Like 2 (Nrf2) and Hypoxia-Inducible Factor 1 (HIF-1) in Tumor Hypoxia.

Targeting CDK4/6 to oppose hypoxia-mediated therapeutic resistance

The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer