Lista de obras - Sandra Duffy - Dominio Público Uruguay

(+)-7-Bromotrypargine: an antimalarial β-carboline from the Australian marine sponge Ancorina sp

article

(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium.

artículo científico publicado en 2014

2,4-Diaminothienopyrimidines as orally active antimalarial agents

artículo científico publicado en 2014

3,5-Diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potential

artículo científico publicado en 2012

3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally

artículo científico publicado en 2017

3-alkylthio-1,2,4-triazine dimers with potent antimalarial activity

artículo científico publicado en 2010

A New Benzopyranyl Cadenane Sesquiterpene and Other Antiplasmodial and Cytotoxic Metabolites from Cleistochlamys kirkii

artículo científico publicado en 2019

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

artículo científico publicado en 2015

A new quinoline epoxide from the Australian plant Drummondita calida ⬇️

artículo científico publicado en 2011

Albopunctatone, an antiplasmodial anthrone-anthraquinone from the Australian ascidian Didemnum albopunctatum

artículo científico publicado en 2012

Aminoazabenzimidazoles, a novel class of orally active antimalarial agents

artículo científico publicado en 2014

An evaluation of Minor Groove Binders as anti-Trypanosoma brucei brucei therapeutics

artículo científico publicado en 2016

Antimalarial 3-arylamino-6-benzylamino-1,2,4,5-tetrazines

artículo científico publicado en 2010

Antimalarial activity of azafluorenone alkaloids from the Australian tree Mitrephora diversifolia ⬇️

artículo científico publicado en 2009

Antimalarial activity of pyrroloiminoquinones from the Australian marine sponge Zyzzya sp. ⬇️

artículo científico publicado en 2012

Antimalarial benzylisoquinoline alkaloid from the rainforest tree Doryphora sassafras ⬇️

artículo científico publicado en 2009

Antimalarial bromotyrosine derivatives from the Australian marine sponge Hyattella sp. ⬇️

artículo científico publicado en 2010

Antiplasmodial β-triketones from the flowers of the Australian tree Angophora woodsiana

artículo científico publicado en 2017

Aplidiopsamine A, an antiplasmodial alkaloid from the temperate Australian ascidian, Aplidiopsis confluata

artículo científico publicado en 2010

Blood schizontocidal and gametocytocidal activity of 3-hydroxy-N'-arylidenepropanehydrazonamides: a new class of antiplasmodial compounds

artículo científico publicado en 2014

Chemical genetics of Plasmodium falciparum

artículo científico publicado en 2010

Citronamides A and B, tetrapeptides from the Australian sponge Citronia astra

artículo científico publicado en 2009

Copper, nickel, and zinc cyclam-amino acid and cyclam-peptide complexes may be synthesized with "click" chemistry and are noncytotoxic

artículo científico publicado en 2011

Development and optimization of a novel 384-well anti-malarial imaging assay validated for high-throughput screening

artículo científico publicado en 2012

Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages

artículo científico publicado en 2014

Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy

artículo científico publicado en 2016

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

artículo científico publicado en 2016

Endiandrin A, a Potent Glucocorticoid Receptor Binder Isolated from the Australian PlantEndiandraanthropophagorum ⬇️

article

Euodenine A: A Small-Molecule Agonist of Human TLR4

artículo científico publicado en 2014

Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans

artículo científico publicado en 2014

Identification and In-Vitro ADME Assessment of a Series of Novel Anti-Malarial Agents Suitable for Hit-to-Lead Chemistry

artículo científico publicado en 2012

Identification of MMV malaria box inhibitors of plasmodium falciparum early-stage gametocytes using a luciferase-based high-throughput assay

artículo científico publicado en 2013

Identification of inhibitors of Plasmodium falciparum gametocyte development

artículo científico publicado en 2013

Identifying common metalloprotease inhibitors by protein fold types using Fourier transform mass spectrometry

artículo científico publicado en 2007

Inhibition of neuronal Ca(2+) influx by gabapentin and pregabalin in the human neocortex

artículo científico publicado en 2002

Kororamide A, a new tribrominated indole alkaloid from the Australian bryozoan Amathia tortuosa

article

Large-scale production of Plasmodium falciparum gametocytes for malaria drug discovery

artículo científico publicado en 2016

Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules.

artículo científico publicado en 2014

Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a SoftFocus kinase library: part 1.

artículo científico publicado en 2014

N-aryl-2-aminobenzimidazoles: novel, efficacious, antimalarial lead compounds

artículo científico publicado en 2014

Naseseazine C, a new anti-plasmodial dimeric diketopiperazine from a marine sediment derived Streptomyces sp

Novel conjugated quinoline-indoles compromise Plasmodium falciparum mitochondrial function and show promising antimalarial activity

artículo científico publicado en 2013

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

artículo científico publicado en 2016

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

artículo científico publicado en 2016

Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity

artículo científico publicado en 2017

Organometallic conjugates of the drug sulfadoxine for combatting antimicrobial resistance.

artículo científico publicado en 2018

Plasmodium falciparum in vitro continuous culture conditions: A comparison of parasite susceptibility and tolerance to anti-malarial drugs throughout the asexual intra-erythrocytic life cycle

artículo científico publicado en 2017

Polyoxygenated Cyclohexenes and Other Constituents of Cleistochlamys kirkii Leaves.

artículo científico publicado en 2016

Prenylated Flavonoids from the Roots of Tephrosia rhodesica

scientific article published on 13 August 2020

Pterocarpans and isoflavones from the root bark of Millettia micans and of Millettia dura

Quinolone-3-diarylethers: a new class of antimalarial drug.

artículo científico publicado en 2013

Repositioning: the fast track to new anti-malarial medicines?

artículo científico publicado en 2014

Rotenoids, Flavonoids, and Chalcones from the Root Bark of Millettia usaramensis

artículo científico publicado en 2015

Screening and hit evaluation of a chemical library against blood-stage Plasmodium falciparum

artículo científico publicado en 2014

Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery.

artículo científico publicado en 2017

Secoiridoids and Iridoids from Morinda asteroscepa

scientific article published on 27 August 2020

Selective anti-malarial minor groove binders

artículo científico publicado en 2016

Synthesis of antimalarial amide analogues based on the plant serrulatane diterpenoid 3,7,8-trihydroxyserrulat-14-en-19-oic acid

artículo científico

Synthesis, antimalarial properties, and SAR studies of alkoxyurea-based HDAC inhibitors.

artículo científico publicado en 2014

The synthesis, antimalarial activity and CoMFA analysis of novel aminoalkylated quercetin analogs

artículo científico publicado en 2014

Thiaplakortones A-D: antimalarial thiazine alkaloids from the Australian marine sponge Plakortis lita

artículo científico publicado en 2013

Three Chalconoids and a Pterocarpene from the Roots of Tephrosia aequilata

artículo científico publicado en 2017

Tomentosones A and B, hexacyclic phloroglucinol derivatives from the Thai shrub Rhodomyrtus tomentosa

artículo científico publicado en 2011

Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials

scientific article published on 17 June 2016

Watsonianone A-C, anti-plasmodial β-triketones from the Australian tree, Corymbia watsoniana

artículo científico publicado en 2012

Wilsoniamines A and B: novel alkaloids from the temperate Australian bryozoan, Amathia wilsoni

article

Lista de obras de Sandra Duffy

(+)-7-Bromotrypargine: an antimalarial β-carboline from the Australian marine sponge Ancorina sp

(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium.

2,4-Diaminothienopyrimidines as orally active antimalarial agents

3,5-Diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potential

3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally

3-alkylthio-1,2,4-triazine dimers with potent antimalarial activity

A New Benzopyranyl Cadenane Sesquiterpene and Other Antiplasmodial and Cytotoxic Metabolites from Cleistochlamys kirkii

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

A new quinoline epoxide from the Australian plant Drummondita calida ⬇️

Albopunctatone, an antiplasmodial anthrone-anthraquinone from the Australian ascidian Didemnum albopunctatum

Aminoazabenzimidazoles, a novel class of orally active antimalarial agents

An evaluation of Minor Groove Binders as anti-Trypanosoma brucei brucei therapeutics

Antimalarial 3-arylamino-6-benzylamino-1,2,4,5-tetrazines

Antimalarial activity of azafluorenone alkaloids from the Australian tree Mitrephora diversifolia ⬇️

Antimalarial activity of pyrroloiminoquinones from the Australian marine sponge Zyzzya sp. ⬇️

Antimalarial benzylisoquinoline alkaloid from the rainforest tree Doryphora sassafras ⬇️

Antimalarial bromotyrosine derivatives from the Australian marine sponge Hyattella sp. ⬇️

Antiplasmodial β-triketones from the flowers of the Australian tree Angophora woodsiana

Aplidiopsamine A, an antiplasmodial alkaloid from the temperate Australian ascidian, Aplidiopsis confluata

Blood schizontocidal and gametocytocidal activity of 3-hydroxy-N'-arylidenepropanehydrazonamides: a new class of antiplasmodial compounds

Chemical genetics of Plasmodium falciparum

Citronamides A and B, tetrapeptides from the Australian sponge Citronia astra

Copper, nickel, and zinc cyclam-amino acid and cyclam-peptide complexes may be synthesized with "click" chemistry and are noncytotoxic

Development and optimization of a novel 384-well anti-malarial imaging assay validated for high-throughput screening

Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages

Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy

Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

Endiandrin A, a Potent Glucocorticoid Receptor Binder Isolated from the Australian PlantEndiandraanthropophagorum ⬇️

Euodenine A: A Small-Molecule Agonist of Human TLR4

Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans

Identification and In-Vitro ADME Assessment of a Series of Novel Anti-Malarial Agents Suitable for Hit-to-Lead Chemistry

Identification of MMV malaria box inhibitors of plasmodium falciparum early-stage gametocytes using a luciferase-based high-throughput assay

Identification of inhibitors of Plasmodium falciparum gametocyte development

Identifying common metalloprotease inhibitors by protein fold types using Fourier transform mass spectrometry

Inhibition of neuronal Ca(2+) influx by gabapentin and pregabalin in the human neocortex

Kororamide A, a new tribrominated indole alkaloid from the Australian bryozoan Amathia tortuosa

Large-scale production of Plasmodium falciparum gametocytes for malaria drug discovery

Lysine acetylation in sexual stage malaria parasites is a target for antimalarial small molecules.

Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a SoftFocus kinase library: part 1.

N-aryl-2-aminobenzimidazoles: novel, efficacious, antimalarial lead compounds

Naseseazine C, a new anti-plasmodial dimeric diketopiperazine from a marine sediment derived Streptomyces sp

Novel conjugated quinoline-indoles compromise Plasmodium falciparum mitochondrial function and show promising antimalarial activity

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity

Organometallic conjugates of the drug sulfadoxine for combatting antimicrobial resistance.

Plasmodium falciparum in vitro continuous culture conditions: A comparison of parasite susceptibility and tolerance to anti-malarial drugs throughout the asexual intra-erythrocytic life cycle

Polyoxygenated Cyclohexenes and Other Constituents of Cleistochlamys kirkii Leaves.

Prenylated Flavonoids from the Roots of Tephrosia rhodesica

Pterocarpans and isoflavones from the root bark of Millettia micans and of Millettia dura

Quinolone-3-diarylethers: a new class of antimalarial drug.

Repositioning: the fast track to new anti-malarial medicines?

Rotenoids, Flavonoids, and Chalcones from the Root Bark of Millettia usaramensis

Screening and hit evaluation of a chemical library against blood-stage Plasmodium falciparum

Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery.

Secoiridoids and Iridoids from Morinda asteroscepa

Selective anti-malarial minor groove binders

Synthesis of antimalarial amide analogues based on the plant serrulatane diterpenoid 3,7,8-trihydroxyserrulat-14-en-19-oic acid

Synthesis, antimalarial properties, and SAR studies of alkoxyurea-based HDAC inhibitors.

The synthesis, antimalarial activity and CoMFA analysis of novel aminoalkylated quercetin analogs

Thiaplakortones A-D: antimalarial thiazine alkaloids from the Australian marine sponge Plakortis lita

Three Chalconoids and a Pterocarpene from the Roots of Tephrosia aequilata

Tomentosones A and B, hexacyclic phloroglucinol derivatives from the Thai shrub Rhodomyrtus tomentosa

Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials

Watsonianone A-C, anti-plasmodial β-triketones from the Australian tree, Corymbia watsoniana

Wilsoniamines A and B: novel alkaloids from the temperate Australian bryozoan, Amathia wilsoni