Lista de obras - Darren R Feldman - Dominio Público Uruguay

A Phase Ib Study of BEZ235, a Dual Inhibitor of Phosphatidylinositol 3-Kinase (PI3K) and Mammalian Target of Rapamycin (mTOR), in Patients With Advanced Renal Cell Carcinoma

artículo científico publicado en 2016

A phase 2 multicenter study of tivantinib (ARQ 197) monotherapy in patients with relapsed or refractory germ cell tumors.

artículo científico publicado en 2013

A review of second-line chemotherapy and prognostic models for disseminated germ cell tumors.

artículo científico publicado en 2011

Are Some Cases of Somatic Type Malignancy Potentially Avoidable?

artículo científico publicado en 2016

Bevacizumab Monotherapy as Salvage Therapy for Advanced Clear Cell Renal Cell Carcinoma Pretreated With Targeted Drugs.

artículo científico publicado en 2015

Beyond stage I germ cell tumors: current status regarding treatment and long-term toxicities.

artículo científico

Bilateral Testicular Germ Cell Tumors in the Era of Multimodal Therapy

artículo científico publicado en 2016

Body Mass Index Is Associated With Higher Lymph Node Counts During Retroperitoneal Lymph Node Dissection ⬇️

artículo científico publicado el 14 de diciembre de 2011

Brain Metastases in Patients With Germ Cell Tumors: Prognostic Factors and Treatment Options--An Analysis From the Global Germ Cell Cancer Group

artículo científico publicado en 2015

Cabozantinib Versus Sunitinib As Initial Targeted Therapy for Patients With Metastatic Renal Cell Carcinoma of Poor or Intermediate Risk: The Alliance A031203 CABOSUN Trial.

artículo científico publicado en 2016

Cabozantinib versus sunitinib as initial therapy for metastatic renal cell carcinoma of intermediate or poor risk (Alliance A031203 CABOSUN randomised trial): Progression-free survival by independent review and overall survival update.

artículo científico publicado en 2018

Characterization and Impact of TERT Promoter Region Mutations on Clinical Outcome in Renal Cell Carcinoma.

artículo científico publicado en 2017

Characterizing recurrent and lethal small renal masses in clear cell renal cell carcinoma using recurrent somatic mutations.

artículo científico publicado en 2017

Cisplatin Therapy Does Not Worsen Renal Function in Severe Antenatal Bartter Syndrome

artículo científico publicado en 2017

Clinical Outcome of Patients with Fibrosis/Necrosis at Post-Chemotherapy Retroperitoneal Lymph Node Dissection for Advanced Germ Cell Tumors

artículo científico publicado en 2016

Clinical Outcome of Retroperitoneal Lymph Node Dissection after Chemotherapy in Patients with Pure Embryonal Carcinoma in the Orchiectomy Specimen.

artículo científico publicado en 2018

Clinical Outcomes of Local and Metastatic Testicular Sex Cord-Stromal Tumors

artículo científico publicado en 2014

Clinical and Genetic Risk Factors for Adverse Metabolic Outcomes in North American Testicular Cancer Survivors.

artículo científico publicado en 2018

Clinical and Genome-Wide Analysis of Cisplatin-Induced Peripheral Neuropathy in Survivors of Adult-Onset Cancer

artículo científico publicado en 2017

Clinical and Genome-Wide Analysis of Multiple Severe Cisplatin-Induced Neurotoxicities in Adult-Onset Cancer Survivors

artículo científico publicado en 2020

Clinical and Genome-Wide Analysis of Serum Platinum Levels after Cisplatin-Based Chemotherapy

scientific article published on 11 July 2019

Clinical and histopathologic characteristics of rash in cancer patients treated with mammalian target of rapamycin inhibitors.

artículo científico publicado en 2012

Clinical impact of residual extraretroperitoneal masses in patients with advanced nonseminomatous germ cell testicular cancer

artículo científico publicado en 2012

Comparative Genomic Profiling of Matched Primary and Metastatic Tumors in Renal Cell Carcinoma

artículo científico publicado en 2017

Contemporary lymph node counts during primary retroperitoneal lymph node dissection.

artículo científico publicado en 2010

Controversies in the Management of Clinical Stage I Seminoma: Carboplatin a Decade in-Time to Start Backing Out.

artículo científico publicado en 2018

Conventional-Dose versus High-Dose Chemotherapy for Relapsed Germ Cell Tumors.

artículo científico publicado en 2018

Cumulative Burden of Morbidity Among Testicular Cancer Survivors After Standard Cisplatin-Based Chemotherapy: A Multi-Institutional Study.

artículo científico publicado en 2018

Curing germ cell tumors after failure of high-dose chemotherapy: progress through clinical trials

artículo científico publicado en 2007

Development and Validation of a Gene-Based Model for Outcome Prediction in Germ Cell Tumors Using a Combined Genomic and Expression Profiling Approach

artículo científico publicado en 2015

Development of a risk stratification system to guide treatment for female germ cell tumors.

artículo científico publicado en 2015

Editorial comment

artículo científico publicado en 2014

Evaluation of lymph node counts in primary retroperitoneal lymph node dissection.

artículo científico publicado en 2010

Everolimus plus bevacizumab is an effective first-line treatment for patients with advanced papillary variant renal cell carcinoma: Final results from a phase II trial

scientific article published on 25 September 2020

Follow-Up Management of Patients With Testicular Cancer: A Multidisciplinary Consensus-Based Approach.

artículo científico

Genetic Determinants of Cisplatin Resistance in Patients With Advanced Germ Cell Tumors

artículo científico publicado en 2016

Genomic Characterization of Renal Medullary Carcinoma and Treatment Outcomes

artículo científico publicado en 2017

Genomic alterations as predictors of survival among patients within a combined cohort with clear cell renal cell carcinoma undergoing cytoreductive nephrectomy

artículo científico publicado en 2017

Good-risk-advanced germ cell tumors: historical perspective and current standards of care.

artículo científico publicado en 2009

Hearing Loss in Adult Survivors of Childhood Cancer Treated with Radiotherapy.

artículo científico publicado en 2018

High Response Rate and Durability Driven by HLA Genetic Diversity in Patients with Kidney Cancer Treated with Lenvatinib and Pembrolizumab

publication published on 26 May 2021

High incidence of thromboembolic events in patients treated with cisplatin-based chemotherapy: a large retrospective analysis

artículo científico publicado en 2011

High-dose chemotherapy and stem cell transplantation for advanced testicular cancer

artículo científico publicado en 2011

Histologic and Oncologic Outcomes Following Liver Mass Resection With Retroperitoneal Lymph Node Dissection in Patients With Nonseminomatous Germ Cell Tumor

artículo científico publicado en 2018

Infectious complications from high-dose chemotherapy and autologous stem cell transplantation for metastatic germ cell tumors

artículo científico publicado en 2008

Integrated Molecular Characterization of Testicular Germ Cell Tumors

article by Hui Shen et al published 12 June 2018 in Cell Reports

Integration of Recurrent Somatic Mutations with Clinical Outcomes: A Pooled Analysis of 1049 Patients with Clear Cell Renal Cell Carcinoma

artículo científico publicado en 2016

Interrogation of a context-specific transcription factor network identifies novel regulators of pluripotency

artículo científico publicado en 2015

Is High Dose Therapy Superior to Conventional Dose Therapy as Initial Treatment for Relapsed Germ Cell Tumors? The TIGER Trial ⬇️

artículo científico publicado el 1 de enero de 2011

Is high-dose chemotherapy effective in patients with relapsed or refractory germ cell tumors?

artículo científico publicado en 2007

Late Relapse of Testicular Germ Cell Tumors

artículo científico publicado en 2015

Late cardiovascular toxicity following chemotherapy for germ cell tumors.

artículo científico publicado en 2012

Long-term mortality in patients with germ cell tumors: effect of primary cancer site on cause of death.

artículo científico publicado en 2013

Medical treatment of advanced testicular cancer.

artículo científico publicado en 2008

Microwave ablation (MWA) for the treatment of a solitary, chemorefractory testicular cancer liver metastasis

artículo científico publicado en 2014

Multi-Institutional Assessment of Adverse Health Outcomes Among North American Testicular Cancer Survivors After Modern Cisplatin-Based Chemotherapy.

artículo científico publicado en 2017

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

artículo científico publicado en 2017

Outcomes After Resection of Postchemotherapy Residual Neck Mass in Patients With Germ Cell Tumors—An Update

artículo científico publicado en 2011

Outcomes in patients with clinical stage III NSGCT who achieve complete clinical response to chemotherapy at extraretroperitoneal disease site.

artículo científico

Paclitaxel, Ifosfamide, and Cisplatin Efficacy for First-Line Treatment of Patients With Intermediate- or Poor-Risk Germ Cell Tumors

artículo científico publicado en 2016

Paclitaxel, ifosfamide and cisplatin (TIP) beyond its original indication for salvage treatment of germ cell tumors

scientific article published on 23 August 2011

Patient-Reported Functional Impairment Due to Hearing Loss and Tinnitus After Cisplatin-Based Chemotherapy

scientific article published in 2023

Pediatric and Adolescent Extracranial Germ Cell Tumors: The Road to Collaboration

artículo científico publicado en 2015

Pelvic Lymph Node Dissection in Patients Treated for Testis Cancer: The Memorial Sloan Kettering Cancer Center Experience

artículo científico publicado en 2016

Phase 1 study of twice weekly pulse dose and daily low-dose erlotinib as initial treatment for patients with EGFR-mutant lung cancers

artículo científico publicado en 2016

Phase 1 trial of everolimus plus sunitinib in patients with metastatic renal cell carcinoma ⬇️

artículo científico publicado el 6 de septiembre de 2011

Phase I study of flavopiridol with oxaliplatin and fluorouracil/leucovorin in advanced solid tumors

artículo científico publicado en 2009

Phase I trial of bevacizumab plus escalated doses of sunitinib in patients with metastatic renal cell carcinoma.

artículo científico publicado en 2009

Phase I/II Trial of Paclitaxel With Ifosfamide Followed by High-Dose Paclitaxel, Ifosfamide, and Carboplatin (TI-TIC) With Autologous Stem Cell Reinfusion for Salvage Treatment of Germ Cell Tumors.

artículo científico publicado en 2015

Phase II Trial and Correlative Genomic Analysis of Everolimus Plus Bevacizumab in Advanced Non-Clear Cell Renal Cell Carcinoma.

artículo científico publicado en 2016

Phase II Trial of ixabepilone in patients with cisplatin-refractory germ cell tumors

artículo científico publicado en 2007

Phase II trial of sunitinib in patients with relapsed or refractory germ cell tumors.

artículo científico publicado en 2009

Practice Makes Perfect: The Rest of the Story in Testicular Cancer as a Model Curable Neoplasm

artículo científico publicado en 2017

Presence of somatic mutations within PIK3CA, AKT, RAS, and FGFR3 but not BRAF in cisplatin-resistant germ cell tumors.

artículo científico publicado en 2014

Progression-free and overall survival in patients with relapsed/refractory germ cell tumors treated with single-agent chemotherapy: endpoints for clinical trial design.

artículo científico publicado en 2011

Quality-adjusted survival with first-line cabozantinib or sunitinib for advanced renal cell carcinoma in the CABOSUN randomized clinical trial (Alliance)

artículo científico publicado en 2020

Rare de novo germline copy-number variation in testicular cancer

artículo científico publicado en 2012

Rates of teratoma and viable cancer at post-chemotherapy retroperitoneal lymph node dissection after induction chemotherapy for good risk nonseminomatous germ cell tumors.

artículo científico publicado en 2014

Re: Hypothyroidism in Patients With Metastatic Renal Cell Carcinoma Treated With Sunitinib

artículo científico publicado en 2007

Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition

artículo científico publicado en 2012

Relationship of Cisplatin-Related Adverse Health Outcomes With Disability and Unemployment Among Testicular Cancer Survivors

scientific article published on 20 March 2020

Reply to L.C. Pagliaro et al

scientific article published on 01 June 2015

Response to Nivolumab in a Patient With Metastatic Clear Cell Renal Cell Carcinoma and End-stage Renal Disease on Dialysis

artículo científico publicado en 2016

Revisiting DNA damage repair, p53-mediated apoptosis and cisplatin sensitivity in germ cell tumors.

artículo científico

Risk of Vascular Toxicity with Platinum Based Chemotherapy in Elderly Patients with Bladder Cancer

scientific article published on 01 September 2015

Salvage high-dose chemotherapy for germ cell tumors.

artículo científico

Sarcomatoid-variant renal cell carcinoma: treatment outcome and survival in advanced disease.

artículo científico publicado en 2011

Solid and Hematologic Neoplasms After Testicular Cancer: A US Population-Based Study of 24 900 Survivors

scientific article published on 17 March 2020

Sunitinib in metastatic renal cell carcinoma: recommendations for management of noncardiovascular toxicities.

artículo científico publicado en 2011

Testicular cancer survivorship: research strategies and recommendations

artículo científico publicado en 2010

The Clinical Activity of PD-1/PD-L1 Inhibitors in Metastatic Non-Clear Cell Renal Cell Carcinoma

artículo científico publicado en 2018

The risk of hand foot skin reaction to pazopanib, a novel multikinase inhibitor: a systematic review of literature and meta-analysis.

scientific article published on 11 March 2011

The risk of skin rash and stomatitis with the mammalian target of rapamycin inhibitor temsirolimus: A systematic review of the literature and meta-analysis ⬇️

artículo científico publicado el 27 de diciembre de 2011

The role of high-dose chemotherapy in the management of germ cell tumors.

artículo científico

Treatment of CD30-Expressing Germ Cell Tumors and Sex Cord Stromal Tumors with Brentuximab Vedotin: Identification and Report of Seven Cases.

artículo científico publicado en 2017

Treatment of stage I seminoma: is it time to change your practice?

artículo científico publicado en 2008

Treatment options for stage I nonseminoma

artículo científico publicado en 2014

Treatment outcome with mTOR inhibitors for metastatic renal cell carcinoma with nonclear and sarcomatoid histologies.

artículo científico publicado en 2014

Tumor Xenografts of Human Clear Cell Renal Cell Carcinoma But Not Corresponding Cell Lines Recapitulate Clinical Response to Sunitinib: Feasibility of Using Biopsy Samples

artículo científico publicado en 2016

Update in germ cell tumours.

artículo científico

Variants in WFS1 and Other Mendelian Deafness Genes Are Associated with Cisplatin-Associated Ototoxicity

artículo científico publicado en 2016

Lista de obras de Darren R Feldman

A Phase Ib Study of BEZ235, a Dual Inhibitor of Phosphatidylinositol 3-Kinase (PI3K) and Mammalian Target of Rapamycin (mTOR), in Patients With Advanced Renal Cell Carcinoma

A phase 2 multicenter study of tivantinib (ARQ 197) monotherapy in patients with relapsed or refractory germ cell tumors.

A review of second-line chemotherapy and prognostic models for disseminated germ cell tumors.

Are Some Cases of Somatic Type Malignancy Potentially Avoidable?

Bevacizumab Monotherapy as Salvage Therapy for Advanced Clear Cell Renal Cell Carcinoma Pretreated With Targeted Drugs.

Beyond stage I germ cell tumors: current status regarding treatment and long-term toxicities.

Bilateral Testicular Germ Cell Tumors in the Era of Multimodal Therapy

Body Mass Index Is Associated With Higher Lymph Node Counts During Retroperitoneal Lymph Node Dissection ⬇️

Brain Metastases in Patients With Germ Cell Tumors: Prognostic Factors and Treatment Options--An Analysis From the Global Germ Cell Cancer Group

Cabozantinib Versus Sunitinib As Initial Targeted Therapy for Patients With Metastatic Renal Cell Carcinoma of Poor or Intermediate Risk: The Alliance A031203 CABOSUN Trial.

Cabozantinib versus sunitinib as initial therapy for metastatic renal cell carcinoma of intermediate or poor risk (Alliance A031203 CABOSUN randomised trial): Progression-free survival by independent review and overall survival update.

Characterization and Impact of TERT Promoter Region Mutations on Clinical Outcome in Renal Cell Carcinoma.

Characterizing recurrent and lethal small renal masses in clear cell renal cell carcinoma using recurrent somatic mutations.

Cisplatin Therapy Does Not Worsen Renal Function in Severe Antenatal Bartter Syndrome

Clinical Outcome of Patients with Fibrosis/Necrosis at Post-Chemotherapy Retroperitoneal Lymph Node Dissection for Advanced Germ Cell Tumors

Clinical Outcome of Retroperitoneal Lymph Node Dissection after Chemotherapy in Patients with Pure Embryonal Carcinoma in the Orchiectomy Specimen.

Clinical Outcomes of Local and Metastatic Testicular Sex Cord-Stromal Tumors

Clinical and Genetic Risk Factors for Adverse Metabolic Outcomes in North American Testicular Cancer Survivors.

Clinical and Genome-Wide Analysis of Cisplatin-Induced Peripheral Neuropathy in Survivors of Adult-Onset Cancer

Clinical and Genome-Wide Analysis of Multiple Severe Cisplatin-Induced Neurotoxicities in Adult-Onset Cancer Survivors

Clinical and Genome-Wide Analysis of Serum Platinum Levels after Cisplatin-Based Chemotherapy

Clinical and histopathologic characteristics of rash in cancer patients treated with mammalian target of rapamycin inhibitors.

Clinical impact of residual extraretroperitoneal masses in patients with advanced nonseminomatous germ cell testicular cancer

Comparative Genomic Profiling of Matched Primary and Metastatic Tumors in Renal Cell Carcinoma

Contemporary lymph node counts during primary retroperitoneal lymph node dissection.

Controversies in the Management of Clinical Stage I Seminoma: Carboplatin a Decade in-Time to Start Backing Out.

Conventional-Dose versus High-Dose Chemotherapy for Relapsed Germ Cell Tumors.

Cumulative Burden of Morbidity Among Testicular Cancer Survivors After Standard Cisplatin-Based Chemotherapy: A Multi-Institutional Study.

Curing germ cell tumors after failure of high-dose chemotherapy: progress through clinical trials

Development and Validation of a Gene-Based Model for Outcome Prediction in Germ Cell Tumors Using a Combined Genomic and Expression Profiling Approach

Development of a risk stratification system to guide treatment for female germ cell tumors.

Editorial comment

Evaluation of lymph node counts in primary retroperitoneal lymph node dissection.

Everolimus plus bevacizumab is an effective first-line treatment for patients with advanced papillary variant renal cell carcinoma: Final results from a phase II trial

Follow-Up Management of Patients With Testicular Cancer: A Multidisciplinary Consensus-Based Approach.

Genetic Determinants of Cisplatin Resistance in Patients With Advanced Germ Cell Tumors

Genomic Characterization of Renal Medullary Carcinoma and Treatment Outcomes

Genomic alterations as predictors of survival among patients within a combined cohort with clear cell renal cell carcinoma undergoing cytoreductive nephrectomy

Good-risk-advanced germ cell tumors: historical perspective and current standards of care.

Hearing Loss in Adult Survivors of Childhood Cancer Treated with Radiotherapy.

High Response Rate and Durability Driven by HLA Genetic Diversity in Patients with Kidney Cancer Treated with Lenvatinib and Pembrolizumab

High incidence of thromboembolic events in patients treated with cisplatin-based chemotherapy: a large retrospective analysis

High-dose chemotherapy and stem cell transplantation for advanced testicular cancer

Histologic and Oncologic Outcomes Following Liver Mass Resection With Retroperitoneal Lymph Node Dissection in Patients With Nonseminomatous Germ Cell Tumor

Infectious complications from high-dose chemotherapy and autologous stem cell transplantation for metastatic germ cell tumors

Integrated Molecular Characterization of Testicular Germ Cell Tumors

Integration of Recurrent Somatic Mutations with Clinical Outcomes: A Pooled Analysis of 1049 Patients with Clear Cell Renal Cell Carcinoma

Interrogation of a context-specific transcription factor network identifies novel regulators of pluripotency

Is High Dose Therapy Superior to Conventional Dose Therapy as Initial Treatment for Relapsed Germ Cell Tumors? The TIGER Trial ⬇️

Is high-dose chemotherapy effective in patients with relapsed or refractory germ cell tumors?

Late Relapse of Testicular Germ Cell Tumors

Late cardiovascular toxicity following chemotherapy for germ cell tumors.

Long-term mortality in patients with germ cell tumors: effect of primary cancer site on cause of death.

Medical treatment of advanced testicular cancer.

Microwave ablation (MWA) for the treatment of a solitary, chemorefractory testicular cancer liver metastasis

Multi-Institutional Assessment of Adverse Health Outcomes Among North American Testicular Cancer Survivors After Modern Cisplatin-Based Chemotherapy.

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

Outcomes After Resection of Postchemotherapy Residual Neck Mass in Patients With Germ Cell Tumors—An Update

Outcomes in patients with clinical stage III NSGCT who achieve complete clinical response to chemotherapy at extraretroperitoneal disease site.

Paclitaxel, Ifosfamide, and Cisplatin Efficacy for First-Line Treatment of Patients With Intermediate- or Poor-Risk Germ Cell Tumors

Paclitaxel, ifosfamide and cisplatin (TIP) beyond its original indication for salvage treatment of germ cell tumors

Patient-Reported Functional Impairment Due to Hearing Loss and Tinnitus After Cisplatin-Based Chemotherapy

Pediatric and Adolescent Extracranial Germ Cell Tumors: The Road to Collaboration

Pelvic Lymph Node Dissection in Patients Treated for Testis Cancer: The Memorial Sloan Kettering Cancer Center Experience

Phase 1 study of twice weekly pulse dose and daily low-dose erlotinib as initial treatment for patients with EGFR-mutant lung cancers

Phase 1 trial of everolimus plus sunitinib in patients with metastatic renal cell carcinoma ⬇️

Phase I study of flavopiridol with oxaliplatin and fluorouracil/leucovorin in advanced solid tumors

Phase I trial of bevacizumab plus escalated doses of sunitinib in patients with metastatic renal cell carcinoma.

Phase I/II Trial of Paclitaxel With Ifosfamide Followed by High-Dose Paclitaxel, Ifosfamide, and Carboplatin (TI-TIC) With Autologous Stem Cell Reinfusion for Salvage Treatment of Germ Cell Tumors.

Phase II Trial and Correlative Genomic Analysis of Everolimus Plus Bevacizumab in Advanced Non-Clear Cell Renal Cell Carcinoma.

Phase II Trial of ixabepilone in patients with cisplatin-refractory germ cell tumors

Phase II trial of sunitinib in patients with relapsed or refractory germ cell tumors.

Practice Makes Perfect: The Rest of the Story in Testicular Cancer as a Model Curable Neoplasm

Presence of somatic mutations within PIK3CA, AKT, RAS, and FGFR3 but not BRAF in cisplatin-resistant germ cell tumors.

Progression-free and overall survival in patients with relapsed/refractory germ cell tumors treated with single-agent chemotherapy: endpoints for clinical trial design.

Quality-adjusted survival with first-line cabozantinib or sunitinib for advanced renal cell carcinoma in the CABOSUN randomized clinical trial (Alliance)

Rare de novo germline copy-number variation in testicular cancer

Rates of teratoma and viable cancer at post-chemotherapy retroperitoneal lymph node dissection after induction chemotherapy for good risk nonseminomatous germ cell tumors.

Re: Hypothyroidism in Patients With Metastatic Renal Cell Carcinoma Treated With Sunitinib