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Lista de obras de Jayesh Desai

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

artículo científico publicado en 2016

A First-Time-In-Human Phase I Clinical Trial of Bispecific Antibody-Targeted, Paclitaxel-Packaged Bacterial Minicells

artículo científico publicado en 2015

A Phase Ib Dose-Escalation and Expansion Study of the BCL2 Inhibitor Venetoclax Combined with Tamoxifen in ER and BCL2-Positive Metastatic Breast Cancer

artículo científico publicado en 2018

A multi-arm phase I dose escalating study of an oral NOTCH inhibitor BMS-986115 in patients with advanced solid tumours.

artículo científico publicado en 2018

A mutant BRAF V600E-specific immunohistochemical assay: correlation with molecular mutation status and clinical outcome in colorectal cancer

artículo científico publicado en 2014

A phase 1, first-in-human study of AMG 900, an orally administered pan-Aurora kinase inhibitor, in adult patients with advanced solid tumors

artículo científico publicado en 2018

A phase I trial to determine safety and pharmacokinetics of ASLAN002, an oral MET superfamily kinase inhibitor, in patients with advanced or metastatic solid cancers.

artículo científico publicado en 2018

A phase Ib/II translational study of sunitinib with neoadjuvant radiotherapy in soft-tissue sarcoma

artículo científico publicado en 2014

An Australasian perspective on sarcoma research, translational biology and clinical trials: the Australasian Sarcoma Study Group (ASSG).

artículo científico publicado en 2014

An initial watch and wait approach is a valid strategy for selected patients with newly diagnosed metastatic colorectal cancer.

artículo científico publicado en 2012

Analysis of cellular phosphatidylinositol (3,4,5)-trisphosphate levels and distribution using confocal fluorescent microscopy

artículo científico publicado en 2010

Analysis of local chronic inflammatory cell infiltrate combined with systemic inflammation improves prognostication in stage II colon cancer independent of standard clinicopathologic criteria

artículo científico

Antiangiogenic therapies targeting the vascular endothelia growth factor signaling system.

artículo científico

Binimetinib, Encorafenib, and Cetuximab Triplet Therapy for Patients With BRAF V600E-Mutant Metastatic Colorectal Cancer: Safety Lead-In Results From the Phase III BEACON Colorectal Cancer Study

scientific article published on 20 March 2019

Blood-based biomarkers of SU11248 activity and clinical outcome in patients with metastatic imatinib-resistant gastrointestinal stromal tumor.

artículo científico publicado en 2007

CART-WHEEL.org: An Ethically Approved Online Database for Patient-Entered Data to Facilitate Rare Cancer Research

artículo científico publicado en 2020

Cetuximab Alone or With Irinotecan for Resistant KRAS-, NRAS-, BRAF- and PIK3CA-wild-type Metastatic Colorectal Cancer: The AGITG Randomized Phase II ICECREAM Study

scientific article published on 08 June 2018

Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer

artículo científico publicado en 2016

Circulating tumor DNA as an early marker of therapeutic response in patients with metastatic colorectal cancer

artículo científico publicado en 2015

Clinical, pharmacodynamic, and pharmacokinetic evaluation of BNC105P: a phase I trial of a novel vascular disrupting agent and inhibitor of cancer cell proliferation.

artículo científico publicado en 2011

Clonal evolution of resistance to imatinib in patients with metastatic gastrointestinal stromal tumors

artículo científico publicado en 2007

Comprehensive mapping of p53 pathway alterations reveals an apparent role for both SNP309 and MDM2 amplification in sarcomagenesis

artículo científico publicado en 2010

Controversies in the management of gastrointestinal stromal tumors

artículo científico publicado en 2014

Cost-effectiveness analysis of imaging surveillance in stage II and III extremity soft tissue sarcoma: an Australian perspective

artículo científico publicado en 2020

Criteria-based curation of a therapy-focused compendium to support treatment recommendations in precision oncology

artículo científico publicado en 2021

DNA copy-number alterations underlie gene expression differences between microsatellite stable and unstable colorectal cancers

artículo científico publicado en 2008

Developing a national database for metastatic colorectal cancer management: perspectives and challenges.

artículo científico publicado en 2013

Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis.

artículo científico publicado en 2012

Dose optimization of tyrosine kinase inhibitors to improve outcomes in GIST

artículo científico publicado el 20 de febrero de 2012

Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial

artículo científico publicado en 2006

Encorafenib, Binimetinib, and Cetuximab in BRAF V600E-Mutated Colorectal Cancer

artículo científico publicado en 2019

Examining the impact of regular aspirin use and PIK3CA mutations on survival in stage 2 colon cancer

artículo científico publicado en 2016

Exploring the feasibility and utility of exome-scale tumour sequencing in a clinical setting

artículo científico publicado en 2018

First-in-Man Dose-Escalation Study of the Selective BRAF Inhibitor RG7256 in Patients with BRAF V600-Mutated Advanced Solid Tumors.

artículo científico

First-in-human phase I clinical trial of a combined immune modulatory approach using TetMYB vaccine and Anti-PD-1 antibody in patients with advanced solid cancer including colorectal or adenoid cystic carcinoma: The MYPHISMO study protocol (NCT03287

artículo científico publicado en 2019

Gemcitabine and vinorelbine combination chemotherapy for patients with advanced soft tissue sarcomas: results of a phase II trial.

artículo científico publicado en 2007

Gender-specific activity of chemotherapy correlates with outcomes in chemosensitive cancers of young adulthood.

artículo científico publicado en 2009

Girdin (GIV) Expression as a Prognostic Marker of Recurrence in Mismatch Repair-Proficient Stage II Colon Cancer

artículo científico publicado en 2016

Histone deacetylase inhibitors in cancer: what have we learned?

artículo científico publicado en 2014

Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors.

artículo científico publicado en 2006

ICECREAM: randomised phase II study of cetuximab alone or in combination with irinotecan in patients with metastatic colorectal cancer with either KRAS, NRAS, BRAF and PI3KCA wild type, or G13D mutated tumours

artículo científico publicado en 2016

Immunomodulation by MYB is associated with tumor relapse in patients with early stage colorectal cancer.

artículo científico publicado en 2016

Impact of BRAF mutation and microsatellite instability on the pattern of metastatic spread and prognosis in metastatic colorectal cancer

artículo científico publicado en 2011

Impact of Diabetes Status and Medication on Presentation, Treatment, and Outcome of Stage II Colon Cancer Patients

artículo científico publicado en 2015

Impact of Primary Tumor Site on Bevacizumab Efficacy in Metastatic Colorectal Cancer

artículo científico publicado en 2016

Impact of body mass index on colorectal cancer treatment and outcomes: need for prospective and comprehensive data.

artículo científico publicado en 2009

Impact of regular aspirin use on overall and cancer-specific survival in patients with colorectal cancer harboring a PIK3CA mutation

artículo científico publicado en 2014

KRAS Mutation Is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer

artículo científico publicado en 2011

KRAS mutation testing of metastatic colorectal cancer in Australia: where are we at?

artículo científico

KRASG12C Inhibition with Sotorasib in Advanced Solid Tumors

scientific article published on 20 September 2020

Lack of clinical activity with crizotinib in a patient with FUS rearranged rhabdomyosarcoma with ALK protein overexpression

scientific article published on 27 August 2019

Long-term efficacy of imatinib mesylate in patients with advanced Tenosynovial Giant Cell Tumor

artículo científico publicado en 2019

MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors

artículo científico publicado en 2018

Management of gastrointestinal stromal tumors in the era of tyrosine kinase inhibitors.

artículo científico publicado en 2002

Mechanistic Insights of an Immunological Adverse Event Induced by an Anti-KIT Antibody Drug Conjugate and Mitigation Strategies

artículo científico publicado en 2018

Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer

artículo científico publicado en 2009

Microsatellite instability status is critical to analysis of survival in stage II colon cancer

artículo científico publicado en 2012

Multicenter retrospective analysis of metastatic colorectal cancer (CRC) with high-level microsatellite instability (MSI-H).

artículo científico publicado en 2014

Neurofibromatosis type 1-associated wild-type gastrointestinal stromal tumor treated with anti-IGF-1R monoclonal antibody.

artículo científico publicado en 2010

Nivolumab for the treatment of colorectal cancer

artículo científico publicado en 2018

Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study.

artículo científico publicado en 2017

Novel Vaccine Targeting Colonic Adenoma: a Pre-clinical Model

scientific article published on 08 January 2019

Novel quality indicators for metastatic colorectal cancer management identify significant variations in these measures across treatment centers in Australia.

artículo científico publicado en 2015

Nutlin-3a efficacy in sarcoma predicted by transcriptomic and epigenetic profiling

artículo científico publicado en 2013

Optimising the management of soft tissue tumours

artículo científico publicado el 1 de junio de 2011

Overview of biomarkers in metastatic colorectal cancer: tumour, blood and patient-related factors.

artículo científico

PIK3CA and PTEN gene and exon mutation-specific clinicopathologic and molecular associations in colorectal cancer

artículo científico publicado en 2013

Pexidartinib versus placebo for advanced tenosynovial giant cell tumour (ENLIVEN): a randomised phase 3 trial

scientific article published on 19 June 2019

Phase I, Open-Label, Dose-Escalation/Dose-Expansion Study of Lifirafenib (BGB-283), an RAF Family Kinase Inhibitor, in Patients With Solid Tumors

artículo científico publicado en 2020

Phase II study of ganitumab, a fully human anti-type-1 insulin-like growth factor receptor antibody, in patients with metastatic Ewing family tumors or desmoplastic small round cell tumors

artículo científico publicado en 2012

Phase Ib study of atezolizumab combined with cobimetinib in patients with solid tumors

scientific article published on 01 July 2019

Precision oncology using a clinician-directed, tailored approach to molecular profiling.

artículo científico publicado en 2017

Primary Tumor Resection in Patients With Metastatic Colorectal Cancer Is Associated With Reversal of Systemic Inflammation and Improved Survival.

artículo científico publicado en 2015

Profound MEK inhibitor response in a cutaneous melanoma harboring a GOLGA4-RAF1 fusion

artículo científico publicado en 2019

Re: Residual treatment disparities after oncology referral for rectal cancer

artículo científico publicado en 2008

Recurrent SPECC1L-NTRK fusions in paediatric sarcoma and brain tumours

artículo científico publicado en 2020

Response assessment in gastrointestinal stromal tumor.

artículo científico publicado en 2011

Response to "Disparities in the use of chemotherapy and monoclonal antibody therapy for elderly advanced colorectal cancer patients in the community oncology setting".

artículo científico publicado en 2009

Response to Cetuximab With or Without Irinotecan in Patients With Refractory Metastatic Colorectal Cancer Harboring the KRAS G13D Mutation: Australasian Gastro-Intestinal Trials Group ICECREAM Study

artículo científico publicado en 2016

SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer

artículo científico publicado en 2013

Safety and pharmacokinetics of motesanib in combination with gemcitabine and erlotinib for the treatment of solid tumors: a phase 1b study.

artículo científico publicado en 2011

Survival Impact of Adjuvant Chemotherapy for Resected Locally Advanced Rectal Adenocarcinoma

artículo científico publicado en 2016

Survival impact of the Australian National Bowel Cancer Screening Programme.

artículo científico publicado en 2015

Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations

artículo científico publicado en 2013

Systematic Review of Clinical Outcomes Following Various Treatment Options for Patients with Extraabdominal Desmoid Tumors

artículo científico publicado en 2018

Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma

artículo científico publicado en 2015

Targeting BRAF mutant metastatic colorectal cancer: clinical implications and emerging therapeutic strategies

artículo científico

The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity

artículo científico publicado en 2019

The past, present, and future of cytotoxic chemotherapy and pathway-directed targeted agents for soft tissue sarcoma.

artículo científico publicado en 2013

The value of networks in driving phase I trials: the Peter MacCallum Cancer Centre experience

artículo científico publicado en 2019

Thyrotoxicosis during sunitinib treatment for renal cell carcinoma.

artículo científico publicado en 2008

Translation of clinical trial outcomes to metastatic colorectal cancer patients in community practice.

artículo científico publicado en 2014

Treatment of patients with primary retroperitoneal sarcoma: predictors of outcome from an Australian specialist sarcoma centre

article

Variations of Surveillance Practice for Patients with Bone Sarcoma: A Survey of Australian Sarcoma Clinicians.

artículo científico publicado en 2017

Wiki-based clinical practice guidelines for the management of adult onset sarcoma: a new paradigm in sarcoma evidence.

artículo científico publicado en 2015

Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancer

artículo científico publicado en 2015

Wither surgical oncology?

scientific article published on 01 January 2019