Lista de obras - Barry Potter - Dominio Público Uruguay

'Click cyclic ADP-ribose': a neutral second messenger mimic

artículo científico publicado en 2014

2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity

artículo científico publicado en 2006

A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion

artículo científico publicado en 2016

A Synthetic Polyphosphoinositide Headgroup Surrogate in Complex with SHIP2 Provides a Rationale for Drug Discovery ⬇️

artículo científico publicado el 27 de febrero de 2012

Adenophostin A and ribophostin, but not inositol 1,4,5-trisphosphate or manno-adenophostin, activate the Ca2+ release-activated Ca2+ current, ICRAC, in weak intracellular Ca2+ buffer ⬇️

artículo científico publicado el 1 de enero de 2002

Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography

artículo científico publicado en 2008

Binding of inositol 1,4,5-trisphosphate (IP3) and adenophostin A to the N-terminal region of the IP3 receptor: thermodynamic analysis using fluorescence polarization with a novel IP3 receptor ligand.

artículo científico publicado en 2010

CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template

artículo científico publicado en 2013

Catalysis-associated conformational changes revealed by human CD38 complexed with a non-hydrolyzable substrate analog

artículo científico publicado en 2007

Chimeric microtubule disruptors

artículo científico publicado en 2010

Design, Synthesis, and Chemical and Biological Properties of Cyclic ADP-4-Thioribose as a Stable Equivalent of Cyclic ADP-Ribose

artículo científico publicado en 2014

E-ring modified steroids as novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

artículo científico publicado en 2005

Estrogen O-sulfamates and their analogues: Clinical steroid sulfatase inhibitors with broad potential

artículo científico publicado en 2015

First synthetic analogues of diphosphoinositol polyphosphates: interaction with PP-InsP5 kinase ⬇️

artículo científico publicado el 28 de noviembre de 2012

Focused libraries of 16-substituted estrone derivatives and modified e-ring steroids: inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

artículo científico publicado en 2006

Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template

artículo científico publicado en 2010

Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response

artículo científico publicado en 2014

Hybrid dual aromatase-steroid sulfatase inhibitors with exquisite picomolar inhibitory activity

artículo científico publicado en 2010

Identification of mammalian Vps24p as an effector of phosphatidylinositol 3,5-bisphosphate-dependent endosome compartmentalization

artículo científico publicado en 2003

Inositol pentakisphosphate promotes apoptosis through the PI 3-K/Akt pathway

artículo científico publicado en 2004

Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.

artículo científico publicado en 2017

Modification of estrone at the 6, 16, and 17 positions: novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

artículo científico publicado en 2006

Nicotinic acid adenine dinucleotide phosphate-mediated calcium signalling in effector T cells regulates autoimmunity of the central nervous system.

artículo científico publicado en 2010

Novel inositol phospholipid headgroup surrogate crystallized in the pleckstrin homology domain of protein kinase Balpha

artículo científico publicado en 2007

Optimisation of tetrahydroisoquinoline-based chimeric microtubule disruptors

artículo científico publicado en 2014

Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase

artículo científico publicado en 2002

Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by analogues of IP3

artículo científico publicado en 2013

Structural Basis for Enzymatic Evolution from a Dedicated ADP-ribosyl Cyclase to a Multifunctional NAD Hydrolase

artículo científico publicado en 2009

Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents

artículo científico publicado en 2008

Structures of human carbonic anhydrase II/inhibitor complexes reveal a second binding site for steroidal and nonsteroidal inhibitors

artículo científico publicado en 2010

Synthesis, anti-tubulin and antiproliferative SAR of steroidomimetic dihydroisoquinolinones

artículo científico publicado en 2014

Synthetic Inositol Phosphate Analogs Reveal that PPIP5K2 Has a Surface-Mounted Substrate Capture Site that Is a Target for Drug Discovery

artículo científico publicado en 2014

The enzymes of human diphosphoinositol polyphosphate metabolism

artículo científico publicado en 2014

The structural biology of oestrogen metabolism ⬇️

artículo científico publicado el 4 de enero de 2013

Lista de obras de Barry Potter

'Click cyclic ADP-ribose': a neutral second messenger mimic

2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity

A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion

A Synthetic Polyphosphoinositide Headgroup Surrogate in Complex with SHIP2 Provides a Rationale for Drug Discovery ⬇️

Adenophostin A and ribophostin, but not inositol 1,4,5-trisphosphate or manno-adenophostin, activate the Ca2+ release-activated Ca2+ current, ICRAC, in weak intracellular Ca2+ buffer ⬇️

Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography

Binding of inositol 1,4,5-trisphosphate (IP3) and adenophostin A to the N-terminal region of the IP3 receptor: thermodynamic analysis using fluorescence polarization with a novel IP3 receptor ligand.

CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template

Catalysis-associated conformational changes revealed by human CD38 complexed with a non-hydrolyzable substrate analog

Chimeric microtubule disruptors

Design, Synthesis, and Chemical and Biological Properties of Cyclic ADP-4-Thioribose as a Stable Equivalent of Cyclic ADP-Ribose

E-ring modified steroids as novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Estrogen O-sulfamates and their analogues: Clinical steroid sulfatase inhibitors with broad potential

First synthetic analogues of diphosphoinositol polyphosphates: interaction with PP-InsP5 kinase ⬇️

Focused libraries of 16-substituted estrone derivatives and modified e-ring steroids: inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template

Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response

Hybrid dual aromatase-steroid sulfatase inhibitors with exquisite picomolar inhibitory activity

Identification of mammalian Vps24p as an effector of phosphatidylinositol 3,5-bisphosphate-dependent endosome compartmentalization

Inositol pentakisphosphate promotes apoptosis through the PI 3-K/Akt pathway

Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.

Modification of estrone at the 6, 16, and 17 positions: novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1.

Nicotinic acid adenine dinucleotide phosphate-mediated calcium signalling in effector T cells regulates autoimmunity of the central nervous system.

Novel inositol phospholipid headgroup surrogate crystallized in the pleckstrin homology domain of protein kinase Balpha

Optimisation of tetrahydroisoquinoline-based chimeric microtubule disruptors

Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase

Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by analogues of IP3

Structural Basis for Enzymatic Evolution from a Dedicated ADP-ribosyl Cyclase to a Multifunctional NAD Hydrolase

Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents

Structures of human carbonic anhydrase II/inhibitor complexes reveal a second binding site for steroidal and nonsteroidal inhibitors

Synthesis, anti-tubulin and antiproliferative SAR of steroidomimetic dihydroisoquinolinones

Synthetic Inositol Phosphate Analogs Reveal that PPIP5K2 Has a Surface-Mounted Substrate Capture Site that Is a Target for Drug Discovery

The enzymes of human diphosphoinositol polyphosphate metabolism

The structural biology of oestrogen metabolism ⬇️