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Lista de obras de Stephen D Ginsberg

A genotype resource for postmortem brain samples from the Autism Tissue Program

artículo científico publicado en 2011

Accumulation of intracellular amyloid-beta peptide (A beta 1-40) in mucopolysaccharidosis brains.

artículo científico publicado en 1999

Age-dependent dysregulation of brain amyloid precursor protein in the Ts65Dn Down syndrome mouse model.

artículo científico publicado en 2009

Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease.

artículo científico publicado en 2007

Alzheimer's-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition.

artículo científico publicado en 2009

Amplification of RNA transcripts using terminal continuation.

artículo científico publicado en 2004

An essential component in steroid synthesis, the steroidogenic acute regulatory protein, is expressed in discrete regions of the brain.

artículo científico publicado en 2002

Apolipoprotein E4 genotype compromises brain exosome production

Attentional function and basal forebrain cholinergic neuron morphology during aging in the Ts65Dn mouse model of Down syndrome

artículo científico publicado en 2015

Brain-Wide Insulin Resistance, Tau Phosphorylation Changes, and Hippocampal Neprilysin and Amyloid-β Alterations in a Monkey Model of Type 1 Diabetes.

artículo científico publicado en 2016

Brain-derived neurotrophic factor (BDNF) and TrkB hippocampal gene expression are putative predictors of neuritic plaque and neurofibrillary tangle pathology

artículo científico publicado en 2019

CA1 pyramidal neuron gene expression mosaics in the Ts65Dn murine model of Down syndrome and Alzheimer's disease following maternal choline supplementation (MCS).

artículo científico publicado en 2018

Calorie Restriction Suppresses Age-Dependent Hippocampal Transcriptional Signatures

artículo científico publicado en 2015

Calorie restriction slows age-related microbiota changes in an Alzheimer's disease model in female mice

artículo científico publicado en 2019

Characterization of the putative cholesterol transport protein metastatic lymph node 64 in the brain

artículo científico publicado en 2006

Cholinotrophic molecular substrates of mild cognitive impairment in the elderly.

artículo científico publicado en 2007

Circulating Aβ40 influences plasma BDNF levels and white matter integrity

Combined histochemical staining, RNA amplification, regional, and single cell cDNA analysis within the hippocampus.

artículo científico publicado en 2004

Combining online and in-person methods to evaluate the content validity of PROMIS fatigue short forms in rheumatoid arthritis

article

Cortical alpha7 nicotinic acetylcholine receptor and beta-amyloid levels in early Alzheimer disease.

artículo científico publicado en 2009

Cystatin C rescues degenerating neurons in a cystatin B-knockout mouse model of progressive myoclonus epilepsy.

artículo científico publicado en 2010

Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease.

artículo científico publicado en 2009

Different inflammatory reactions to vitamin D3 among the lateral, third and fourth ventricular choroid plexuses of the rat.

artículo científico publicado en 2008

Differential regulation of catechol-O-methyltransferase expression in a mouse model of aggression.

artículo científico publicado en 2011

Distribution of an APP homolog, APLP2, in the mouse olfactory system: a potential role for APLP2 in axogenesis.

artículo científico publicado en 1995

Effects of Maternal Choline Supplementation on the Septohippocampal Cholinergic System in the Ts65Dn Mouse Model of Down Syndrome

artículo científico publicado en 2015

Effects of early-life penicillin exposure on the gut microbiome and frontal cortex and amygdala gene expression

artículo científico publicado en 2021

Effects of social deprivation in prepubescent rhesus monkeys: immunohistochemical analysis of the neurofilament protein triplet in the hippocampal formation.

artículo científico publicado en 1993

Enhanced exosome secretion in Down syndrome brain - a protective mechanism to alleviate neuronal endosomal abnormalities

artículo científico

Expression and proteolytic processing of the amyloid precursor protein is unaffected by the expression of the three human apolipoprotein E alleles in the brains of mice

artículo científico publicado en 2022

Expression profile analysis of hippocampal CA1 pyramidal neurons in aged Ts65Dn mice, a model of Down syndrome (DS) and Alzheimer's disease (AD).

artículo científico publicado en 2014

Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice

artículo científico publicado en 2014

Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons

artículo científico publicado en 2000

Expression profiling and pharmacotherapeutic development in the central nervous system.

artículo científico publicado en 2004

Expression profiling in neuropsychiatric disorders: emphasis on glutamate receptors in bipolar disorder

artículo científico publicado en 2011

Expression profiling in the aging brain: a perspective.

artículo científico publicado en 2005

Expression profiling suggests microglial impairment in HIV neuropathogenesis.

artículo científico publicado en 2018

Expression profiling using human tissues in combination with RNA amplification and microarray analysis: assessment of Langerhans cell histiocytosis.

artículo científico publicado en 2005

Fimbria-fornix transection and excitotoxicity produce similar neurodegeneration in the septum.

artículo científico publicado en 1999

Fimbria-fornix transections selectively down-regulate subtypes of glutamate transporter and glutamate receptor proteins in septum and hippocampus.

artículo científico publicado en 1996

Frontal cortex and striatal cellular and molecular pathobiology in individuals with Down syndrome with and without dementia

scientific article published on 07 February 2019

Functional genomic methodologies.

artículo científico publicado en 2006

Galanin fiber hyperinnervation preserves neuroprotective gene expression in cholinergic basal forebrain neurons in Alzheimer's disease.

artículo científico publicado en 2009

Galanin fiber hypertrophy within the cholinergic nucleus basalis during the progression of Alzheimer's disease.

artículo científico publicado en 2006

Galanin hyperinnervation upregulates choline acetyltransferase expression in cholinergic basal forebrain neurons in Alzheimer's disease.

artículo científico publicado en 2008

Gender differences in neurotrophin and glutamate receptor expression in cholinergic nucleus basalis neurons during the progression of Alzheimer's disease

artículo científico publicado el 17 de marzo de 2011

Gene Profiling of Nucleus Basalis Tau Containing Neurons in Chronic Traumatic Encephalopathy: A Chronic Effects of Neurotrauma Consortium Study

artículo científico publicado en 2018

Gene expression levels assessed by CA1 pyramidal neuron and regional hippocampal dissections in Alzheimer's disease

artículo científico publicado en 2011

Gene expression profiles of cholinergic nucleus basalis neurons in Alzheimer's disease.

artículo científico publicado en 2002

Glutamatergic transmission aberration: a major cause of behavioral deficits in a murine model of Down's syndrome.

artículo científico publicado en 2014

Hippocampal ProNGF Signaling Pathways and β-Amyloid Levels in Mild Cognitive Impairment and Alzheimer Disease

artículo científico publicado el 1 de noviembre de 2012

Hippocampal endosomal, lysosomal, and autophagic dysregulation in mild cognitive impairment: correlation with aβ and tau pathology

artículo científico publicado en 2015

Hippocampal plasticity during the progression of Alzheimer's disease

artículo científico publicado en 2015

Human cholinergic basal forebrain: chemoanatomy and neurologic dysfunction.

artículo científico publicado en 2003

Identification of CSPα clients reveals a role in dynamin 1 regulation.

artículo científico publicado en 2012

In vivo MRI identifies cholinergic circuitry deficits in a Down syndrome model.

scientific article published on 03 January 2008

Increased Expression of Readthrough Acetylcholinesterase Variants in the Brains of Alzheimer's Disease Patients

artículo científico publicado en 2016

Long-term effects of maternal choline supplementation on CA1 pyramidal neuron gene expression in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease

artículo científico publicado en 2019

Maternal Choline Supplementation Alters Basal Forebrain Cholinergic Neuron Gene Expression in the Ts65Dn Mouse Model of Down Syndrome

artículo científico publicado en 2019

Maternal Choline Supplementation: A Potential Prenatal Treatment for Down Syndrome and Alzheimer's Disease.

artículo científico publicado en 2015

Maternal choline supplementation differentially alters the basal forebrain cholinergic system of young-adult Ts65Dn and disomic mice.

artículo científico publicado en 2014

Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome

artículo científico publicado en 2013

Maternal choline supplementation improves spatial mapping and increases basal forebrain cholinergic neuron number and size in aged Ts65Dn mice

artículo científico publicado en 2014

Maternal choline supplementation programs greater activity of the phosphatidylethanolamine N-methyltransferase (PEMT) pathway in adult Ts65Dn trisomic mice

artículo científico publicado en 2014

Measurement of myelin basic protein and of anti-basic protein antibodies by ELISA utilizing biotinylated antibodies

artículo científico publicado en 1983

Mechanisms underlying insulin deficiency-induced acceleration of β-amyloidosis in a mouse model of Alzheimer's disease

artículo científico publicado en 2012

Methods and compositions for amplification and detection of microRNAs (miRNAs) and noncoding RNAs (ncRNAs) using the signature sequence amplification method (SSAM).

artículo científico publicado en 2014

Microarray analysis of CA1 pyramidal neurons in a mouse model of tauopathy reveals progressive synaptic dysfunction.

artículo científico publicado en 2011

Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression

artículo científico publicado en 2010

Mild cognitive impairment: pathology and mechanisms.

artículo científico publicado en 2011

Mitotic Figures in the Median Eminence of the Hypothalamus

artículo científico publicado el 1 de agosto de 2010

Molecular and cellular pathophysiology of preclinical Alzheimer's disease

artículo científico publicado en 2016

Nerve Growth Factor Pathobiology During the Progression of Alzheimer's Disease

scientific article published on 01 July 2019

Neuron-specific age-related decreases in dopamine receptor subtype mRNAs

artículo científico publicado en 2003

Neuronal ceroid lipofuscinosis with DNAJC5/CSPα mutation has PPT1 pathology and exhibit aberrant protein palmitoylation.

artículo científico publicado en 2015

Neuronal gene expression profiling: uncovering the molecular biology of neurodegenerative disease.

artículo científico publicado en 2006

Neuroprotective Role for Galanin in Alzheimer’s Disease

artículo científico publicado el 1 de enero de 2010

Non-NMDA glutamate receptors are present throughout the primate hypothalamus

artículo científico publicado en 1995

Noradrenergic innervation of the hypothalamus of rhesus monkeys: distribution of dopamine-beta-hydroxylase immunoreactive fibers and quantitative analysis of varicosities in the paraventricular nucleus.

artículo científico publicado en 1993

Noradrenergic innervation of vasopressin- and oxytocin-containing neurons in the hypothalamic paraventricular nucleus of the macaque monkey: quantitative analysis using double-label immunohistochemistry and confocal laser microscopy.

artículo científico publicado en 1994

Partial BACE1 reduction in a Down syndrome mouse model blocks Alzheimer-related endosomal anomalies and cholinergic neurodegeneration: role of APP-CTF.

artículo científico publicado en 2015

Plasma BDNF levels vary in relation to body weight in females

artículo científico publicado en 2012

Presence and phosphorylation of transcription factors in developing dendrites

artículo científico publicado en 1998

Pretangle pathology within cholinergic nucleus basalis neurons coincides with neurotrophic and neurotransmitter receptor gene dysregulation during the progression of Alzheimer's disease.

artículo científico publicado en 2018

Protein homeostasis gene dysregulation in pretangle-bearing nucleus basalis neurons during the progression of Alzheimer's disease

artículo científico publicado en 2016

RNA amplification in brain tissues.

artículo científico publicado en 2002

RNA sequestration to pathological lesions of neurodegenerative diseases.

artículo científico publicado en 1998

Rac1b increases with progressive tau pathology within cholinergic nucleus basalis neurons in Alzheimer's disease.

artículo científico publicado en 2011

Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease.

artículo científico publicado en 2004

Reduction of β-amyloid and γ-secretase by calorie restriction in female Tg2576 mice

artículo científico publicado en 2014

Regional deafferentation down-regulates subtypes of glutamate transporter proteins

scientific article published on 01 December 1995

Regional selectivity of rab5 and rab7 protein upregulation in mild cognitive impairment and Alzheimer's disease

artículo científico publicado en 2010

Selective decline of neurotrophin and neurotrophin receptor genes within CA1 pyramidal neurons and hippocampus proper: Correlation with cognitive performance and neuropathology in mild cognitive impairment and Alzheimer's disease

artículo científico publicado en 2017

Sequestration of RNA in Alzheimer's disease neurofibrillary tangles and senile plaques.

artículo científico publicado en 1997

Sex differences in the cholinergic basal forebrain in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.

artículo científico publicado en 2013

Sex- and brain region-specific acceleration of β-amyloidogenesis following behavioral stress in a mouse model of Alzheimer's disease.

artículo científico publicado en 2010

Single-cell gene expression analysis: implications for neurodegenerative and neuropsychiatric disorders.

artículo científico publicado en 2004

Synaptic gene dysregulation within hippocampal CA1 pyramidal neurons in mild cognitive impairment.

artículo científico publicado en 2013

Systemic pathology in aged mouse models of Down's syndrome and Alzheimer's disease.

artículo científico publicado en 2008

Target identification for CNS diseases by transcriptional profiling.

scientific article published on 15 October 2008

Terminal continuation (TC) RNA amplification without second strand synthesis

artículo científico publicado en 2008

The AMPA glutamate receptor GluR3 is enriched in oxytocinergic magnocellular neurons and is localized at synapses

scientific article published on 01 March 1995

The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction

artículo científico publicado en 2020

The noradrenergic innervation density of the monkey paraventricular nucleus is not altered by early social deprivation.

artículo científico publicado en 1993

The steroidogenic acute regulatory protein is expressed in steroidogenic cells of the day-old brain.

artículo científico publicado en 2004

The stress-induced transcription factor NR4A1 adjusts mitochondrial function and synapse number in prefrontal cortex.

artículo científico publicado en 2018

Transcriptional profiling of small samples in the central nervous system

artículo científico publicado en 2008

Ultrastructural analysis of the progression of neurodegeneration in the septum following fimbria–fornix transection

artículo científico publicado el 1 de octubre de 1998

Upregulation of select rab GTPases in cholinergic basal forebrain neurons in mild cognitive impairment and Alzheimer's disease.

artículo científico publicado en 2011

Vacuolar pathology in the median eminence of the hypothalamus after hyponatremia.

artículo científico publicado en 2011

Withdrawal of BDNF from hippocampal cultures leads to changes in genes involved in synaptic function

artículo científico publicado en 2014