Lista de obras - Elisabetta Ciani - Dominio Público Uruguay

APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome

article

APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.

artículo científico publicado en 2011

Activation of the ornithine decarboxylase-polyamine system and induction of c-fos and p53 expression in relation to excitotoxic neuronal apoptosis in normal and microencephalic rats.

artículo científico publicado en 1998

Age-related impairment of olfactory bulb neurogenesis in the Ts65Dn mouse model of Down syndrome

artículo científico publicado en 2013

Akt pathway mediates a cGMP-dependent survival role of nitric oxide in cerebellar granule neurones

artículo científico publicado en 2002

Brain nitric oxide and its dual role in neurodegeneration/neuroprotection: understanding molecular mechanisms to devise drug approaches

artículo científico publicado en 2003

CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/glycogen synthase kinase-3beta/beta-catenin signaling

artículo científico publicado en 2010

CDKL5 deficiency entails sleep apneas in mice

artículo científico publicado en 2017

CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling

scientific article published on 22 March 2019

CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells.

artículo científico publicado en 2012

Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with Down syndrome and in Ts65Dn mice

artículo científico publicado en 2007

Cell cycle elongation impairs proliferation of cerebellar granule cell precursors in the Ts65Dn mouse, an animal model for Down syndrome

artículo científico publicado en 2008

Choline acetyltransferase activity at different ages in brain of Ts65Dn mice, an animal model for Down's syndrome and related neurodegenerative diseases

artículo científico publicado en 2006

Chronic neonatal blockade of NMDA receptor does not affect developmental polyamine metabolism but results in altered response to the excitotoxic induction of ornithine decarboxylase.

artículo científico publicado en 1994

Chronic pre-explant blockade of the NMDA receptor affects survival of cerebellar granule cells explanted in vitro.

artículo científico publicado en 1997

Correction to: Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons

artículo científico publicado en 2020

Cyclic AMP-mediated regulation of transcription factor Lot1 expression in cerebellar granule cells

artículo científico publicado en 2005

Decreased excitotoxic sensitivity in the olfactory cortex of adult rats after neonatal NMDA blockade.

artículo científico publicado en 1994

Developmental expression of the cell cycle and apoptosis controlling gene, Lot1, in the rat cerebellum and in cultures of cerebellar granule cells

artículo científico publicado en 2003

Dietary restriction differentially protects from neurodegeneration in animal models of excitotoxicity

artículo científico publicado en 2004

Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome

artículo científico publicado en 2010

Early pharmacotherapy with fluoxetine rescues dendritic pathology in the Ts65Dn mouse model of down syndrome

artículo científico publicado en 2012

Early-occurring proliferation defects in peripheral tissues of the Ts65Dn mouse model of Down syndrome are associated with patched1 over expression

artículo científico publicado en 2012

Effect of early isolation on signal transfer in the entorhinal cortex-dentate-hippocampal system.

artículo científico publicado en 2005

HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder

artículo científico publicado en 2016

Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder.

artículo científico publicado en 2018

Immunohistochemical localization of calbindin-D28K in telencephalic regions of microencephalic rats.

artículo científico publicado en 1994

Impact of environmental enrichment on neurogenesis in the dentate gyrus during the early postnatal period

artículo científico publicado en 2011

Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons

scientific article published on 30 January 2020

Induction of the PAC1-R (PACAP-type I receptor) gene by p53 and Zac.

artículo científico publicado en 1999

Induction of type I PACAP receptor expression by the new zinc finger protein Zac1 and p53

artículo científico publicado en 1998

Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome

artículo científico publicado en 2015

Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder

artículo científico publicado en 2015

Is it possible to improve neurodevelopmental abnormalities in Down syndrome?

artículo científico publicado en 2011

Lithium Restores Age-related Olfactory Impairment in the Ts65Dn Mouse Model of Down Syndrome

artículo científico publicado en 2016

Lithium restores neurogenesis in the subventricular zone of the Ts65Dn mouse, a model for Down syndrome

artículo científico publicado en 2009

Long-lasting effects of chronic neonatal blockade of N-methyl-D-aspartate receptor through the competitive antagonist CGP 39551 in rats.

artículo científico publicado en 1994

Long-term effect of neonatal inhibition of APP gamma-secretase on hippocampal development in the Ts65Dn mouse model of Down syndrome

artículo científico publicado en 2017

Long-term effects of neonatal treatment with fluoxetine on cognitive performance in Ts65Dn mice

artículo científico publicado en 2014

Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling.

artículo científico publicado en 2014

Lot1 is a key element of the pituitary adenylate cyclase-activating polypeptide (PACAP)/cyclic AMP pathway that negatively regulates neuronal precursor proliferation

artículo científico publicado en 2009

Mapping pathological phenotypes in a mouse model of CDKL5 disorder

artículo científico publicado en 2014

Neonatal isolation impairs neurogenesis in the dentate gyrus of the guinea pig.

artículo científico publicado en 2007

Neurochemical correlates of nicotine neurotoxicity on rat habenulo-interpeduncular cholinergic neurons

artículo científico publicado en 2005

Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome

artículo científico publicado en 2007

Neurotoxicity of polyamines and pharmacological neuroprotection in cultures of rat cerebellar granule cells.

artículo científico publicado en 1997

Nitric oxide negatively regulates proliferation and promotes neuronal differentiation through N-Myc downregulation

artículo científico publicado en 2004

Nitric oxide protects neuroblastoma cells from apoptosis induced by serum deprivation through cAMP-response element-binding protein (CREB) activation

artículo científico publicado en 2002

Nitric oxide regulates cGMP-dependent cAMP-responsive element binding protein phosphorylation and Bcl-2 expression in cerebellar neurons: implication for a survival role of nitric oxide

artículo científico publicado en 2002

Ornithine decarboxylase is differentially induced by kainic acid during brain development in the rat.

artículo científico publicado en 1993

Pharmacotherapy with fluoxetine restores functional connectivity from the dentate gyrus to field CA3 in the Ts65Dn mouse model of down syndrome

artículo científico publicado en 2013

Postnatal neurogenesis in the dentate gyrus of the guinea pig.

artículo científico publicado en 2005

Prenatal pharmacotherapy rescues brain development in a Down's syndrome mouse model.

artículo científico publicado en 2013

Proliferation of cerebellar precursor cells is negatively regulated by nitric oxide in newborn rat.

artículo científico publicado en 2006

Role of nitric oxide in the regulation of neuronal proliferation, survival and differentiation

artículo científico publicado en 2004

Sex differences in the hippocampal dentate gyrus of the guinea-pig before puberty ⬇️

artículo científico publicado el 1 de enero de 2003

Short- and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome

artículo científico publicado en 2016

Structural, neurochemical and behavioural consequences of neonatal blockade of NMDA receptor through chronic treatment with CGP 39551 or MK-801.

artículo científico publicado en 1993

The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for Down syndrome

artículo científico publicado en 2013

The place of choline acetyltransferase activity measurement in the "cholinergic hypothesis" of neurodegenerative diseases

artículo científico publicado en 2007

Timing of therapies for Down syndrome: the sooner, the better

artículo científico publicado en 2015

Treatment with the GSK3-beta inhibitor Tideglusib improves hippocampal development and memory performance in juvenile, but not adult, Cdkl5 knockout mice

artículo científico publicado en 2018

Widespread impairment of cell proliferation in the neonate Ts65Dn mouse, a model for Down syndrome.

artículo científico publicado en 2009

Widespread proliferation impairment and hypocellularity in the cerebellum of fetuses with down syndrome

artículo científico publicado en 2010

hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer

artículo científico publicado en 1998

Lista de obras de Elisabetta Ciani

APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome

APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.

Activation of the ornithine decarboxylase-polyamine system and induction of c-fos and p53 expression in relation to excitotoxic neuronal apoptosis in normal and microencephalic rats.

Age-related impairment of olfactory bulb neurogenesis in the Ts65Dn mouse model of Down syndrome

Akt pathway mediates a cGMP-dependent survival role of nitric oxide in cerebellar granule neurones

Brain nitric oxide and its dual role in neurodegeneration/neuroprotection: understanding molecular mechanisms to devise drug approaches

CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/glycogen synthase kinase-3beta/beta-catenin signaling

CDKL5 deficiency entails sleep apneas in mice

CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling

CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells.

Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with Down syndrome and in Ts65Dn mice

Cell cycle elongation impairs proliferation of cerebellar granule cell precursors in the Ts65Dn mouse, an animal model for Down syndrome

Choline acetyltransferase activity at different ages in brain of Ts65Dn mice, an animal model for Down's syndrome and related neurodegenerative diseases

Chronic neonatal blockade of NMDA receptor does not affect developmental polyamine metabolism but results in altered response to the excitotoxic induction of ornithine decarboxylase.

Chronic pre-explant blockade of the NMDA receptor affects survival of cerebellar granule cells explanted in vitro.

Correction to: Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons

Cyclic AMP-mediated regulation of transcription factor Lot1 expression in cerebellar granule cells

Decreased excitotoxic sensitivity in the olfactory cortex of adult rats after neonatal NMDA blockade.

Developmental expression of the cell cycle and apoptosis controlling gene, Lot1, in the rat cerebellum and in cultures of cerebellar granule cells

Dietary restriction differentially protects from neurodegeneration in animal models of excitotoxicity

Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome

Early pharmacotherapy with fluoxetine rescues dendritic pathology in the Ts65Dn mouse model of down syndrome

Early-occurring proliferation defects in peripheral tissues of the Ts65Dn mouse model of Down syndrome are associated with patched1 over expression

Effect of early isolation on signal transfer in the entorhinal cortex-dentate-hippocampal system.

HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder

Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder.

Immunohistochemical localization of calbindin-D28K in telencephalic regions of microencephalic rats.

Impact of environmental enrichment on neurogenesis in the dentate gyrus during the early postnatal period

Increased DNA Damage and Apoptosis in CDKL5-Deficient Neurons

Induction of the PAC1-R (PACAP-type I receptor) gene by p53 and Zac.

Induction of type I PACAP receptor expression by the new zinc finger protein Zac1 and p53

Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome

Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder

Is it possible to improve neurodevelopmental abnormalities in Down syndrome?

Lithium Restores Age-related Olfactory Impairment in the Ts65Dn Mouse Model of Down Syndrome

Lithium restores neurogenesis in the subventricular zone of the Ts65Dn mouse, a model for Down syndrome

Long-lasting effects of chronic neonatal blockade of N-methyl-D-aspartate receptor through the competitive antagonist CGP 39551 in rats.

Long-term effect of neonatal inhibition of APP gamma-secretase on hippocampal development in the Ts65Dn mouse model of Down syndrome

Long-term effects of neonatal treatment with fluoxetine on cognitive performance in Ts65Dn mice

Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling.

Lot1 is a key element of the pituitary adenylate cyclase-activating polypeptide (PACAP)/cyclic AMP pathway that negatively regulates neuronal precursor proliferation

Mapping pathological phenotypes in a mouse model of CDKL5 disorder

Neonatal isolation impairs neurogenesis in the dentate gyrus of the guinea pig.

Neurochemical correlates of nicotine neurotoxicity on rat habenulo-interpeduncular cholinergic neurons

Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome

Neurotoxicity of polyamines and pharmacological neuroprotection in cultures of rat cerebellar granule cells.

Nitric oxide negatively regulates proliferation and promotes neuronal differentiation through N-Myc downregulation

Nitric oxide protects neuroblastoma cells from apoptosis induced by serum deprivation through cAMP-response element-binding protein (CREB) activation

Nitric oxide regulates cGMP-dependent cAMP-responsive element binding protein phosphorylation and Bcl-2 expression in cerebellar neurons: implication for a survival role of nitric oxide

Ornithine decarboxylase is differentially induced by kainic acid during brain development in the rat.

Pharmacotherapy with fluoxetine restores functional connectivity from the dentate gyrus to field CA3 in the Ts65Dn mouse model of down syndrome

Postnatal neurogenesis in the dentate gyrus of the guinea pig.

Prenatal pharmacotherapy rescues brain development in a Down's syndrome mouse model.

Proliferation of cerebellar precursor cells is negatively regulated by nitric oxide in newborn rat.

Role of nitric oxide in the regulation of neuronal proliferation, survival and differentiation

Sex differences in the hippocampal dentate gyrus of the guinea-pig before puberty ⬇️

Short- and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome

Structural, neurochemical and behavioural consequences of neonatal blockade of NMDA receptor through chronic treatment with CGP 39551 or MK-801.

The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for Down syndrome

The place of choline acetyltransferase activity measurement in the "cholinergic hypothesis" of neurodegenerative diseases

Timing of therapies for Down syndrome: the sooner, the better

Treatment with the GSK3-beta inhibitor Tideglusib improves hippocampal development and memory performance in juvenile, but not adult, Cdkl5 knockout mice

Widespread impairment of cell proliferation in the neonate Ts65Dn mouse, a model for Down syndrome.

Widespread proliferation impairment and hypocellularity in the cerebellum of fetuses with down syndrome

hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer