Lista de obras - Sandra Pellegrini - Dominio Público Uruguay

21 Functional analyses of three human TYK2 variants

281

scholarly article by Stephan Wilmes published in September 2013

4 Parameters governing interferon α2/β differential activities

A loss-of-function IFNAR1 allele in Polynesia underlies severe viral diseases in homozygotes

artículo científico publicado en 2022

A natural mutation in the Tyk2 pseudokinase domain underlies altered susceptibility of B10.Q/J mice to infection and autoimmunity

artículo científico publicado en 2003

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

scientific journal article

Activation of the protein tyrosine kinase tyk2 by interferon alpha/beta

artículo científico publicado en 1994

Amplification and excision of integrated polyoma DNA sequences require a functional origin of replication.

artículo científico publicado en 1984

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

artículo científico publicado en 1994

Basal ubiquitin-independent internalization of interferon alpha receptor is prevented by Tyk2-mediated masking of a linear endocytic motif

artículo científico publicado en 2008

Biochemical monitoring of the early endocytic traffic of the type I interferon receptor

artículo científico publicado en 2010

Biochemical monitoring of the early endocytic traffic of the type I interferon receptor

Comparable potency of IFNalpha2 and IFNbeta on immediate JAK/STAT activation but differential down-regulation of IFNAR2.

artículo científico publicado en 2007

Copy number variations and founder effect underlying complete IL-10Rβ deficiency in Portuguese kindreds

artículo científico publicado en 2018

Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN- / on antigen cross-presentation

artículo científico publicado en 2006

Differences in Activity between α and β Type I Interferons Explored by Mutational Analysis

scientific article published in Journal of Biological Chemistry

Differential responsiveness to IFN-alpha and IFN-beta of human mature DC through modulation of IFNAR expression.

artículo científico publicado en 2006

Down-modulation of type 1 interferon responses by receptor cross-competition for a shared Jak kinase

artículo científico publicado en 2001

Early events in signalling by interferons.

artículo científico publicado en 1993

Erratum: Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

artículo científico publicado en 2015

Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense

artículo científico publicado en 2009

Expression of IFNγR2 mutated in a dileucine internalization motif reinstates IFNγ signaling and apoptosis in human T lymphocytes

artículo científico publicado en 2010

Functional characterization of naturally occurring genetic variants in the human TLR1-2-6 gene family

artículo científico publicado en 2011

Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways

artículo científico publicado en 2007

Hepatitis B virus X protein inhibits extracellular IFN-α-mediated signal transduction by downregulation of type I IFN receptor

artículo científico publicado en 2012

Herpes simplex encephalitis in a patient with a distinctive form of inherited IFNAR1 deficiency

scientific article published on 22 September 2020

Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome

artículo científico publicado en 2016

Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

artículo científico publicado en 2014

IL4 and IL13 receptors share the γc chain and activate STAT6, STAT3 and STAT5 proteins in normal human B cells

artículo científico publicado en 1996

ISG15 deficiency and increased viral resistance in humans but not mice

artículo científico publicado en 2016

Identification of Signalling Components in Tyrosine Kinase Cascades Using Phosphopeptide Affinity Chromatography

article published in 1997

Interferon alpha inhibits a Src-mediated pathway necessary for Shigella-induced cytoskeletal rearrangements in epithelial cells

artículo científico publicado en 1998

Jamip1 (marlin-1) defines a family of proteins interacting with janus kinases and microtubules.

artículo científico publicado en 2004

Janus kinase-dependent activation of insulin receptor substrate 1 in response to interleukin-4, oncostatin M, and the interferons

scientific journal article

Ligand-independent pathway that controls stability of interferon alpha receptor

artículo científico publicado en 2007

Mycolactone subverts immunity by selectively blocking the Sec61 translocon.

artículo científico publicado en 2016

NF-κB is required for STAT-4 expression during dendritic cell maturation

scholarly article by Maria Elena Remoli et al published 17 October 2006 in Journal of Leukocyte Biology

P111 USP18 establishes the transcriptional and anti-proliferative interferon alpha/beta differential

P171 Costimulation of IL-10 expression by type I interferon in human CD4 T cells

PS1-029. Dynamics of the Type I interferon receptor assembly in the plasma membrane

PS1-70 An USP18-based negative feedback control induced by Type I and Type III interferons specifically inactivates interferon α response

Receptor density is key to the alpha2/beta interferon differential activities.

scientific article published on 29 June 2009

Receptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signaling

artículo científico publicado en 2015

Récepteurs aux cytokines et signalisation transmembranaire : le modèle des interférons α/β

SS2-3 A cross-talk between the Stat3/SOCS3 and the IRS-1/PI3K/p70S6K pathways regulates antiproliferative activity of IFNβ

STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling.

artículo científico publicado en 2017

T cell receptor signal initiation induced by low-grade stimulation requires the cooperation of LAT in human T cells.

artículo científico publicado en 2010

TYK2 activity promotes ligand-induced IFNAR1 proteolysis

artículo científico publicado en 2006

The Stat3-activating Tyk2 V678F mutant does not up-regulate signaling through the type I interferon receptor but confers ligand hypersensitivity to a homodimeric receptor

artículo científico publicado en 2008

The amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptor

artículo científico publicado en 1997

The cyclin D1 carboxyl regulatory domain controls the division and differentiation of hematopoietic cells

artículo científico publicado en 2016

The receptor interaction region of Tyk2 contains a motif required for its nuclear localization.

artículo científico publicado en 2001

The structure, regulation and function of the Janus kinases (JAKs) and the signal transducers and activators of transcription (STATs).

artículo científico publicado en 1997

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

artículo científico publicado en 2003

Translational control as the basis of the differential antiproliferative potency of IFNα2 and IFNβ

Tuberculosis and impaired IL-23-dependent IFN-γ immunity in humans homozygous for a common missense variant

scientific article published on 01 December 2018

Two common disease-associated TYK2 variants impact exon splicing and TYK2 dosage

artículo científico publicado en 2020

Two rare disease-associated Tyk2 variants are catalytically impaired but signaling competent.

artículo científico publicado en 2013

Tyk2 and Stat3 regulate brown adipose tissue differentiation and obesity

artículo científico publicado en 2012

Type I interferon potentiates T-cell receptor mediated induction of IL-10-producing CD4⁺ T cells.

artículo científico publicado en 2013

Type I interferon-enhanced IL-10 expression in human CD4 T cells is regulated by STAT3, STAT2, and BATF transcription factors

artículo científico publicado en 2017

USP18 and ISG15 coordinately impact on SKP2 and cell cycle progression

USP18 establishes the transcriptional and anti-proliferative interferon α/β differential

artículo científico publicado en 2012

USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon α response

artículo científico publicado en 2011

Lista de obras de Sandra Pellegrini

21 Functional analyses of three human TYK2 variants

281

4 Parameters governing interferon α2/β differential activities

A loss-of-function IFNAR1 allele in Polynesia underlies severe viral diseases in homozygotes

A natural mutation in the Tyk2 pseudokinase domain underlies altered susceptibility of B10.Q/J mice to infection and autoimmunity

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

Activation of the protein tyrosine kinase tyk2 by interferon alpha/beta

Amplification and excision of integrated polyoma DNA sequences require a functional origin of replication.

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

Basal ubiquitin-independent internalization of interferon alpha receptor is prevented by Tyk2-mediated masking of a linear endocytic motif

Biochemical monitoring of the early endocytic traffic of the type I interferon receptor

Biochemical monitoring of the early endocytic traffic of the type I interferon receptor

Comparable potency of IFNalpha2 and IFNbeta on immediate JAK/STAT activation but differential down-regulation of IFNAR2.

Copy number variations and founder effect underlying complete IL-10Rβ deficiency in Portuguese kindreds

Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN- / on antigen cross-presentation

Differences in Activity between α and β Type I Interferons Explored by Mutational Analysis

Differential responsiveness to IFN-alpha and IFN-beta of human mature DC through modulation of IFNAR expression.

Down-modulation of type 1 interferon responses by receptor cross-competition for a shared Jak kinase

Early events in signalling by interferons.

Erratum: Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense

Expression of IFNγR2 mutated in a dileucine internalization motif reinstates IFNγ signaling and apoptosis in human T lymphocytes

Functional characterization of naturally occurring genetic variants in the human TLR1-2-6 gene family

Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways

Hepatitis B virus X protein inhibits extracellular IFN-α-mediated signal transduction by downregulation of type I IFN receptor

Herpes simplex encephalitis in a patient with a distinctive form of inherited IFNAR1 deficiency

Human USP18 deficiency underlies type 1 interferonopathy leading to severe pseudo-TORCH syndrome

Human intracellular ISG15 prevents interferon-α/β over-amplification and auto-inflammation

IL4 and IL13 receptors share the γc chain and activate STAT6, STAT3 and STAT5 proteins in normal human B cells

ISG15 deficiency and increased viral resistance in humans but not mice

Identification of Signalling Components in Tyrosine Kinase Cascades Using Phosphopeptide Affinity Chromatography

Interferon alpha inhibits a Src-mediated pathway necessary for Shigella-induced cytoskeletal rearrangements in epithelial cells

Jamip1 (marlin-1) defines a family of proteins interacting with janus kinases and microtubules.

Janus kinase-dependent activation of insulin receptor substrate 1 in response to interleukin-4, oncostatin M, and the interferons

Ligand-independent pathway that controls stability of interferon alpha receptor

Mycolactone subverts immunity by selectively blocking the Sec61 translocon.

NF-κB is required for STAT-4 expression during dendritic cell maturation

P111 USP18 establishes the transcriptional and anti-proliferative interferon alpha/beta differential

P171 Costimulation of IL-10 expression by type I interferon in human CD4 T cells

PS1-029. Dynamics of the Type I interferon receptor assembly in the plasma membrane

PS1-70 An USP18-based negative feedback control induced by Type I and Type III interferons specifically inactivates interferon α response

Receptor density is key to the alpha2/beta interferon differential activities.

Receptor dimerization dynamics as a regulatory valve for plasticity of type I interferon signaling

Récepteurs aux cytokines et signalisation transmembranaire : le modèle des interférons α/β

SS2-3 A cross-talk between the Stat3/SOCS3 and the IRS-1/PI3K/p70S6K pathways regulates antiproliferative activity of IFNβ

STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling.

T cell receptor signal initiation induced by low-grade stimulation requires the cooperation of LAT in human T cells.

TYK2 activity promotes ligand-induced IFNAR1 proteolysis

The Stat3-activating Tyk2 V678F mutant does not up-regulate signaling through the type I interferon receptor but confers ligand hypersensitivity to a homodimeric receptor

The amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptor

The cyclin D1 carboxyl regulatory domain controls the division and differentiation of hematopoietic cells

The receptor interaction region of Tyk2 contains a motif required for its nuclear localization.

The structure, regulation and function of the Janus kinases (JAKs) and the signal transducers and activators of transcription (STATs).

The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.

Translational control as the basis of the differential antiproliferative potency of IFNα2 and IFNβ

Tuberculosis and impaired IL-23-dependent IFN-γ immunity in humans homozygous for a common missense variant

Two common disease-associated TYK2 variants impact exon splicing and TYK2 dosage

Two rare disease-associated Tyk2 variants are catalytically impaired but signaling competent.

Tyk2 and Stat3 regulate brown adipose tissue differentiation and obesity

Type I interferon potentiates T-cell receptor mediated induction of IL-10-producing CD4⁺ T cells.

Type I interferon-enhanced IL-10 expression in human CD4 T cells is regulated by STAT3, STAT2, and BATF transcription factors

USP18 and ISG15 coordinately impact on SKP2 and cell cycle progression

USP18 establishes the transcriptional and anti-proliferative interferon α/β differential

USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon α response