Lista de obras - Stefan Magez - Dominio Público Uruguay

A conserved flagellar pocket exposed high mannose moiety is used by African trypanosomes as a host cytokine binding molecule.

artículo científico publicado en 2001

Adenylate cyclases of Trypanosoma brucei inhibit the innate immune response of the host

artículo científico publicado en 2012

Affinity is an important determinant of the anti-trypanosome activity of nanobodies

artículo científico publicado en 2012

African Trypanosomes Undermine Humoral Responses and Vaccine Development: Link with Inflammatory Responses?

artículo científico publicado en 2017

African Trypanosomiasis-Associated Anemia: The Contribution of the Interplay between Parasites and the Mononuclear Phagocyte System

artículo científico publicado en 2018

African trypanosomiasis and antibodies: implications for vaccination, therapy and diagnosis

artículo científico publicado en 2009

African trypanosomiasis: new insights for disease control. Preface

artículo científico publicado en 2010

African trypanosomosis: from immune escape and immunopathology to immune intervention

artículo científico publicado en 2007

An Anti-proteome Nanobody Library Approach Yields a Specific Immunoassay for Trypanosoma congolense Diagnosis Targeting Glycosomal Aldolase

artículo científico publicado en 2016

An Unbiased Immunization Strategy Results in the Identification of Enolase as a Potential Marker for Nanobody-Based Detection of Trypanosoma evansi

artículo científico publicado en 2020

Antibody-mediated control of Trypanosoma vivax infection fails in the absence of tumour necrosis factor

artículo científico publicado en 2014

Camelid immunoglobulins and nanobody technology.

artículo científico publicado en 2008

Chronic Trypanosoma congolense infections in mice cause a sustained disruption of the B-cell homeostasis in the bone marrow and spleen.

artículo científico publicado en 2014

Coinfection With Confers Protection Against Cutaneous Leishmaniasis

artículo científico publicado en 2018

Comparative evaluation of the nested ITS PCR against the 18S PCR-RFLP in a survey of bovine trypanosomiasis in Kwale County, Kenya

artículo científico publicado en 2016

Contributions of experimental mouse models to the understanding of African trypanosomiasis

artículo científico publicado en 2008

Control of Trypanosoma evansi infection is IgM mediated and does not require a type I inflammatory response

artículo científico publicado en 2007

Convergent evolution of cytokines

scientific article published in Nature

Correction: Experimental African trypanosome infection suppresses the development of multiple myeloma in mice by inducing intrinsic apoptosis of malignant plasma cells.

artículo científico publicado en 2018

Corrigendum to "DNA detection of Trypanosoma evansi: Diagnostic validity of a new assay based on loop-mediated isothermal amplification (LAMP)" [Vet. Parasitol. 250 (2018) 1-6].

artículo científico publicado en 2018

Curative drug treatment of trypanosomosis leads to the restoration of B-cell lymphopoiesis and splenic B-cell compartments.

artículo científico publicado en 2015

Current status of vaccination against African trypanosomiasis.

artículo científico publicado en 2010

Deletion of IL-4Ralpha on CD4 T cells renders BALB/c mice resistant to Leishmania major infection.

artículo científico publicado en 2007

Detection of pathogen-specific antibodies by loop-mediated isothermal amplification

artículo científico publicado en 2015

Development of a Nanobody-based lateral flow assay to detect active Trypanosoma congolense infections.

artículo científico publicado en 2018

Development of a pHrodo-based assay for the assessment of in vitro and in vivo erythrophagocytosis during experimental trypanosomosis

artículo científico publicado en 2015

Development of a recombinase polymerase amplification lateral flow assay for the detection of active Trypanosoma evansi infections

scientific article published on 18 February 2020

Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm

artículo científico publicado en 2003

Escape mechanisms of African trypanosomes: why trypanosomosis is keeping us awake

artículo científico publicado en 2014

Experimental African Trypanosome Infection by Needle Passage or Natural Tsetse Fly Challenge Thwarts the Development of Collagen-Induced Arthritis in DBA/1 Prone Mice via an Impairment of Antigen Specific B Cell Autoantibody Titers

artículo científico publicado en 2015

Experimental African trypanosome infection suppresses the development of multiple myeloma in mice by inducing intrinsic apoptosis of malignant plasma cells.

artículo científico publicado en 2017

Functionalization of gold nanoparticles with nanobodies through physical adsorption

article published in 2017

Generation of a nanobody targeting the paraflagellar rod protein of trypanosomes

artículo científico publicado en 2014

Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection

scientific article published on 03 February 2020

High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis

artículo científico publicado en 2011

IFN-γ mediates early B-cell loss in experimental African trypanosomosis

artículo científico publicado en 2015

IL-27 Signaling Is Crucial for Survival of Mice Infected with African Trypanosomes via Preventing Lethal Effects of CD4+ T Cells and IFN-γ.

artículo científico publicado en 2015

Identification of a tryptophan-like epitope borne by the variable surface glycoprotein (VSG) of African trypanosomes.

artículo científico publicado en 2006

Immune Evasion Strategies of Trypanosoma brucei within the Mammalian Host: Progression to Pathogenicity

artículo científico publicado en 2016

In situ microscopy analysis reveals local innate immune response developed around Brucella infected cells in resistant and susceptible mice

artículo científico publicado en 2012

In vivo characterization of two additional Leishmania donovani strains using the murine and hamster model.

artículo científico publicado en 2016

Insufficiently defined genetic background confounds phenotypes in transgenic studies as exemplified by malaria infection in Tlr9 knockout mice

artículo científico publicado en 2011

Interferon‐γ and Nitric Oxide in Combination with Antibodies Are Key Protective Host Immune Factors duringTrypanosoma congolenseTc13 Infections

artículo científico publicado en 2006

Interleukin-12p70 deficiency increases survival and diminishes pathology in Trypanosoma congolense infection

artículo científico publicado en 2008

Interleukin‐12p70–Dependent Interferon‐γ Production Is Crucial for Resistance in African Trypanosomiasis

article

Iron Homeostasis and Trypanosoma brucei Associated Immunopathogenicity Development: A Battle/Quest for Iron

artículo científico

Isolation of Trypanosoma brucei brucei Infection-Derived Splenic Marginal Zone B Cells Based on CD1dHigh/B220High Surface Expression in a Two-Step MACS-FACS Approach

artículo científico publicado en 2020

MIF-Mediated Hemodilution Promotes Pathogenic Anemia in Experimental African Trypanosomosis

artículo científico publicado en 2016

Maintenance of B cells during chronic murine Trypanosoma brucei gambiense infection

artículo científico publicado en 2016

Monovinyl sulfone β-cyclodextrin. A flexible drug carrier system

artículo científico publicado en 2013

Mouse models for pathogenic African trypanosomes: unravelling the immunology of host-parasite-vector interactions.

artículo científico publicado en 2011

Murine tumour necrosis factor plays a protective role during the initial phase of the experimental infection with Trypanosoma brucei brucei.

artículo científico publicado en 1993

NK-, NKT- and CD8-Derived IFNγ Drives Myeloid Cell Activation and Erythrophagocytosis, Resulting in Trypanosomosis-Associated Acute Anemia

artículo científico publicado en 2015

Nanobodies As Tools to Understand, Diagnose, and Treat African Trypanosomiasis

artículo científico publicado en 2017

Nanobody conjugated PLGA nanoparticles for active targeting of African Trypanosomiasis.

artículo científico publicado en 2014

Neutrophils enhance early Trypanosoma brucei infection onset

scientific article published in Scientific Reports

Nitric oxide production by endotoxin preparations in TLR4-deficient mice

artículo científico publicado en 2013

Novel primer sequences for polymerase chain reaction-based detection of Trypanosoma brucei gambiense

artículo científico publicado en 2002

P75 tumor necrosis factor-receptor shedding occurs as a protective host response during African trypanosomiasis

artículo científico publicado en 2004

Parallel selection of multiple anti-infectome Nanobodies without access to purified antigens

artículo científico publicado en 2007

Production, purification and crystallization of a trans-sialidase from Trypanosoma vivax

artículo científico publicado en 2015

Receptor-mediated and lectin-like activities of carp (Cyprinus carpio) TNF-alpha.

artículo científico publicado en 2009

Reprint of: The non-mammalian MIF superfamily

artículo científico publicado en 2017

Role of iron homeostasis in trypanosomiasis-associated anemia

artículo científico publicado en 2008

STAT6 Mediates Footpad Immunopathology in the Absence of IL-12p40 Following Infection of Susceptible BALB/c Mice With Leishmania major

artículo científico publicado en 2018

Scrutinizing the mechanisms underlying the induction of anemia of inflammation through GPI-mediated modulation of macrophage activation in a model of African trypanosomiasis.

artículo científico publicado en 2010

Selective pressure can influence the resistance of Trypanosoma congolense to normal human serum

artículo científico publicado en 2002

Single-cell transcriptome profiling and the use of AID deficient mice reveal that B cell activation combined with antibody class switch recombination and somatic hypermutation do not benefit the control of experimental trypanosomosis

artículo científico publicado en 2021

Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis

artículo científico publicado en 2015

Specific uptake of tumor necrosis factor-alpha is involved in growth control of Trypanosoma brucei.

artículo científico publicado en 1997

Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8.

artículo científico publicado en 2008

Structural and kinetic characterization of Trypanosoma congolense pyruvate kinase

scientific article published on 19 February 2020

Structural basis for the high specificity of a Trypanosoma congolense immunoassay targeting glycosomal aldolase

artículo científico publicado en 2017

T. brucei infection reduces B lymphopoiesis in bone marrow and truncates compensatory splenic lymphopoiesis through transitional B-cell apoptosis

artículo científico publicado en 2011

The COMBAT project: controlling and progressively minimizing the burden of vector-borne animal trypanosomosis in Africa

artículo científico publicado en 2022

The Enrichment of Histomonas meleagridis and Its Pathogen-Specific Protein Analysis: A First Step to Shed Light on Its Virulence

artículo científico publicado en 2016

The glycosyl-inositol-phosphate and dimyristoylglycerol moieties of the glycosylphosphatidylinositol anchor of the trypanosome variant-specific surface glycoprotein are distinct macrophage-activating factors ⬇️

artículo científico publicado el 15 de febrero de 1998

The non-mammalian MIF superfamily.

artículo científico publicado en 2016

The role of B-cells and IgM antibodies in parasitemia, anemia, and VSG switching in Trypanosoma brucei-infected mice

artículo científico publicado en 2008

The serum resistance-associated gene as a diagnostic tool for the detection of Trypanosoma brucei rhodesiense

artículo científico publicado en 2002

Trypanosoma brucei Co-opts NK Cells to Kill Splenic B2 B Cells

artículo científico publicado en 2016

Trypanosoma brucei brucei causes a rapid and persistent influx of neutrophils in the spleen of infected mice

scientific article published on 21 August 2019

Trypanosomiasis-induced B cell apoptosis results in loss of protective anti-parasite antibody responses and abolishment of vaccine-induced memory responses

artículo científico publicado en 2008

Tsetse fly saliva accelerates the onset of Trypanosoma brucei infection in a mouse model associated with a reduced host inflammatory response

artículo científico publicado en 2006

Tsetse fly saliva biases the immune response to Th2 and induces anti-vector antibodies that are a useful tool for exposure assessment

artículo científico publicado en 2006

Tsetse salivary gland proteins 1 and 2 are high affinity nucleic acid binding proteins with residual nuclease activity

artículo científico publicado en 2012

Tumor Necrosis Factor (TNF) Receptor–1 (TNFp55) Signal Transduction and Macrophage‐Derived Soluble TNF Are Crucial for Nitric Oxide–MediatedTrypanosoma congolenseParasite Killing

artículo científico publicado en 2007

Using detergent-enhanced LAMP for African trypanosome detection in human cerebrospinal fluid and implications for disease staging

artículo científico publicado en 2019

Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA.

artículo científico publicado en 2014

VSG-GPI anchors of African trypanosomes: their role in macrophage activation and induction of infection-associated immunopathology

artículo científico publicado en 2002

Vaccination against trypanosomiasis: can it be done or is the trypanosome truly the ultimate immune destroyer and escape artist?

artículo científico publicado en 2011

iNOS-producing inflammatory dendritic cells constitute the major infected cell type during the chronic Leishmania major infection phase of C57BL/6 resistant mice

artículo científico publicado en 2009

Lista de obras de Stefan Magez

A conserved flagellar pocket exposed high mannose moiety is used by African trypanosomes as a host cytokine binding molecule.

Adenylate cyclases of Trypanosoma brucei inhibit the innate immune response of the host

Affinity is an important determinant of the anti-trypanosome activity of nanobodies

African Trypanosomes Undermine Humoral Responses and Vaccine Development: Link with Inflammatory Responses?

African Trypanosomiasis-Associated Anemia: The Contribution of the Interplay between Parasites and the Mononuclear Phagocyte System

African trypanosomiasis and antibodies: implications for vaccination, therapy and diagnosis

African trypanosomiasis: new insights for disease control. Preface

African trypanosomosis: from immune escape and immunopathology to immune intervention

An Anti-proteome Nanobody Library Approach Yields a Specific Immunoassay for Trypanosoma congolense Diagnosis Targeting Glycosomal Aldolase

An Unbiased Immunization Strategy Results in the Identification of Enolase as a Potential Marker for Nanobody-Based Detection of Trypanosoma evansi

Antibody-mediated control of Trypanosoma vivax infection fails in the absence of tumour necrosis factor

Camelid immunoglobulins and nanobody technology.

Chronic Trypanosoma congolense infections in mice cause a sustained disruption of the B-cell homeostasis in the bone marrow and spleen.

Coinfection With Confers Protection Against Cutaneous Leishmaniasis

Comparative evaluation of the nested ITS PCR against the 18S PCR-RFLP in a survey of bovine trypanosomiasis in Kwale County, Kenya

Contributions of experimental mouse models to the understanding of African trypanosomiasis

Control of Trypanosoma evansi infection is IgM mediated and does not require a type I inflammatory response

Convergent evolution of cytokines

Correction: Experimental African trypanosome infection suppresses the development of multiple myeloma in mice by inducing intrinsic apoptosis of malignant plasma cells.

Corrigendum to "DNA detection of Trypanosoma evansi: Diagnostic validity of a new assay based on loop-mediated isothermal amplification (LAMP)" [Vet. Parasitol. 250 (2018) 1-6].

Curative drug treatment of trypanosomosis leads to the restoration of B-cell lymphopoiesis and splenic B-cell compartments.

Current status of vaccination against African trypanosomiasis.

Deletion of IL-4Ralpha on CD4 T cells renders BALB/c mice resistant to Leishmania major infection.

Detection of pathogen-specific antibodies by loop-mediated isothermal amplification

Development of a Nanobody-based lateral flow assay to detect active Trypanosoma congolense infections.

Development of a pHrodo-based assay for the assessment of in vitro and in vivo erythrophagocytosis during experimental trypanosomosis

Development of a recombinase polymerase amplification lateral flow assay for the detection of active Trypanosoma evansi infections

Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm

Escape mechanisms of African trypanosomes: why trypanosomosis is keeping us awake

Experimental African Trypanosome Infection by Needle Passage or Natural Tsetse Fly Challenge Thwarts the Development of Collagen-Induced Arthritis in DBA/1 Prone Mice via an Impairment of Antigen Specific B Cell Autoantibody Titers

Experimental African trypanosome infection suppresses the development of multiple myeloma in mice by inducing intrinsic apoptosis of malignant plasma cells.

Functionalization of gold nanoparticles with nanobodies through physical adsorption

Generation of a nanobody targeting the paraflagellar rod protein of trypanosomes

Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection

High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis

IFN-γ mediates early B-cell loss in experimental African trypanosomosis

IL-27 Signaling Is Crucial for Survival of Mice Infected with African Trypanosomes via Preventing Lethal Effects of CD4+ T Cells and IFN-γ.

Identification of a tryptophan-like epitope borne by the variable surface glycoprotein (VSG) of African trypanosomes.

Immune Evasion Strategies of Trypanosoma brucei within the Mammalian Host: Progression to Pathogenicity

In situ microscopy analysis reveals local innate immune response developed around Brucella infected cells in resistant and susceptible mice

In vivo characterization of two additional Leishmania donovani strains using the murine and hamster model.

Insufficiently defined genetic background confounds phenotypes in transgenic studies as exemplified by malaria infection in Tlr9 knockout mice

Interferon‐γ and Nitric Oxide in Combination with Antibodies Are Key Protective Host Immune Factors duringTrypanosoma congolenseTc13 Infections

Interleukin-12p70 deficiency increases survival and diminishes pathology in Trypanosoma congolense infection

Interleukin‐12p70–Dependent Interferon‐γ Production Is Crucial for Resistance in African Trypanosomiasis

Iron Homeostasis and Trypanosoma brucei Associated Immunopathogenicity Development: A Battle/Quest for Iron

Isolation of Trypanosoma brucei brucei Infection-Derived Splenic Marginal Zone B Cells Based on CD1dHigh/B220High Surface Expression in a Two-Step MACS-FACS Approach

MIF-Mediated Hemodilution Promotes Pathogenic Anemia in Experimental African Trypanosomosis

Maintenance of B cells during chronic murine Trypanosoma brucei gambiense infection

Monovinyl sulfone β-cyclodextrin. A flexible drug carrier system

Mouse models for pathogenic African trypanosomes: unravelling the immunology of host-parasite-vector interactions.

Murine tumour necrosis factor plays a protective role during the initial phase of the experimental infection with Trypanosoma brucei brucei.

NK-, NKT- and CD8-Derived IFNγ Drives Myeloid Cell Activation and Erythrophagocytosis, Resulting in Trypanosomosis-Associated Acute Anemia

Nanobodies As Tools to Understand, Diagnose, and Treat African Trypanosomiasis

Nanobody conjugated PLGA nanoparticles for active targeting of African Trypanosomiasis.

Neutrophils enhance early Trypanosoma brucei infection onset

Nitric oxide production by endotoxin preparations in TLR4-deficient mice

Novel primer sequences for polymerase chain reaction-based detection of Trypanosoma brucei gambiense

P75 tumor necrosis factor-receptor shedding occurs as a protective host response during African trypanosomiasis

Parallel selection of multiple anti-infectome Nanobodies without access to purified antigens

Production, purification and crystallization of a trans-sialidase from Trypanosoma vivax

Receptor-mediated and lectin-like activities of carp (Cyprinus carpio) TNF-alpha.

Reprint of: The non-mammalian MIF superfamily

Role of iron homeostasis in trypanosomiasis-associated anemia

STAT6 Mediates Footpad Immunopathology in the Absence of IL-12p40 Following Infection of Susceptible BALB/c Mice With Leishmania major

Scrutinizing the mechanisms underlying the induction of anemia of inflammation through GPI-mediated modulation of macrophage activation in a model of African trypanosomiasis.

Selective pressure can influence the resistance of Trypanosoma congolense to normal human serum

Single-cell transcriptome profiling and the use of AID deficient mice reveal that B cell activation combined with antibody class switch recombination and somatic hypermutation do not benefit the control of experimental trypanosomosis

Specific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African Trypanosomiasis

Specific uptake of tumor necrosis factor-alpha is involved in growth control of Trypanosoma brucei.

Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8.

Structural and kinetic characterization of Trypanosoma congolense pyruvate kinase

Structural basis for the high specificity of a Trypanosoma congolense immunoassay targeting glycosomal aldolase

T. brucei infection reduces B lymphopoiesis in bone marrow and truncates compensatory splenic lymphopoiesis through transitional B-cell apoptosis

The COMBAT project: controlling and progressively minimizing the burden of vector-borne animal trypanosomosis in Africa

The Enrichment of Histomonas meleagridis and Its Pathogen-Specific Protein Analysis: A First Step to Shed Light on Its Virulence

The glycosyl-inositol-phosphate and dimyristoylglycerol moieties of the glycosylphosphatidylinositol anchor of the trypanosome variant-specific surface glycoprotein are distinct macrophage-activating factors ⬇️

The non-mammalian MIF superfamily.

The role of B-cells and IgM antibodies in parasitemia, anemia, and VSG switching in Trypanosoma brucei-infected mice