Lista de obras - Guglielmo Roma - Dominio Público Uruguay

A Simple and Efficient CRISPR Technique for Protein Tagging

scientific article published on 05 December 2020

A comparative transcriptomic analysis of replicating and dormant liver stages of the relapsing malaria parasite Plasmodium cynomolgi.

artículo científico publicado en 2017

A comprehensive assessment of RNA-seq protocols for degraded and low-quantity samples

artículo científico publicado en 2017

A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells

artículo científico publicado en 2007

A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte

artículo científico publicado en 2018

AS601245, an Anti-Inflammatory JNK Inhibitor, and Clofibrate Have a Synergistic Effect in Inducing Cell Responses and in Affecting the Gene Expression Profile in CaCo-2 Colon Cancer Cells ⬇️

artículo científico publicado el 29 de febrero de 2012

AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration

artículo científico publicado en 2019

Active poly(ADPribose) metabolism in DNAase- and salt-resistant rat testis chromatin with high transcriptional activity/competence

scientific journal article

Age-Related Gene Expression Signature in Rats Demonstrate Early, Late, and Linear Transcriptional Changes from Multiple Tissues

artículo científico publicado en 2019

Age-associated inflammation inhibits epidermal stem cell function

artículo científico publicado en 2012

An iron-dependent metabolic vulnerability underlies VPS34-dependence in RKO cancer cells

scientific article published on 24 August 2020

Author Correction: CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma

artículo científico publicado en 2020

CGG Repeat-Induced FMR1 Silencing Depends on the Expansion Size in Human iPSCs and Neurons Carrying Unmethylated Full Mutations

artículo científico publicado en 2016

CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency.

artículo científico publicado en 2016

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma

scientific article published on 09 December 2019

Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution

scientific article published on 01 September 2020

CellSIUS provides sensitive and specific detection of rare cell populations from complex single cell RNA-seq data

scholarly article published 9 January 2019

CellSIUS provides sensitive and specific detection of rare cell populations from complex single-cell RNA-seq data

artículo científico publicado en 2019

Comparative transcriptomics of early dipteran development

artículo científico publicado en 2013

Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice

artículo científico publicado en 2015

Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice

artículo científico publicado en 2016

Corrigendum: The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size

artículo científico publicado en 2016

Decatransin, a new natural product inhibiting protein translocation at the Sec61/SecYEG translocon

artículo científico publicado en 2015

Discovery of a ZIP7 inhibitor from a Notch pathway screen

scientific article published on 14 January 2019

E-box-independent regulation of transcription and differentiation by MYC.

artículo científico publicado en 2011

Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx

artículo científico publicado en 2016

Farnesoid X Receptor Agonism, Acetyl-Coenzyme A Carboxylase Inhibition, and Back Translation of Clinically Observed Endpoints of De Novo Lipogenesis in a Murine NASH Model

artículo científico publicado en 2019

Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62

artículo científico publicado en 2016

Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy

artículo científico publicado en 2017

Genomic Analysis Revealed New Oncogenic Signatures in TP53-Mutant Hepatocellular Carcinoma.

artículo científico publicado en 2018

Hi-Cpipe: a pipeline for high-throughput chromosome capture

HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis.

artículo científico publicado en 2017

HumMeth27QCReport: an R package for quality control and primary analysis of Illumina Infinium methylation data

artículo científico publicado en 2011

IRF2 is a master regulator of human keratinocyte stem cell fate

artículo científico publicado en 2019

Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells.

artículo científico publicado en 2017

Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

artículo científico publicado en 2016

Identification of the C3a Receptor (C3AR1) as the Target of the VGF-derived Peptide TLQP-21 in Rodent Cells ⬇️

artículo científico publicado el 12 de agosto de 2013

Immune cell landscaping reveals a protective role for regulatory T cells during kidney injury and fibrosis

artículo científico publicado en 2020

Integration of multi-omics data of a genome-reduced bacterium: Prevalence of post-transcriptional regulation and its correlation with protein abundances

artículo científico

Lack of sik1 in mouse embryonic stem cells impairs cardiomyogenesis by down-regulating the cyclin-dependent kinase inhibitor p57kip2

scientific journal article

Liver biopsy derived induced pluripotent stem cells provide unlimited supply for the generation of hepatocyte-like cells

artículo científico publicado en 2019

MiR-210 promotes sensory hair cell formation in the organ of corti

artículo científico publicado en 2016

MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae

artículo científico publicado en 2014

Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells

artículo científico publicado en 2012

PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma

scientific article published on 20 August 2019

PRGdb 2.0: towards a community-based database model for the analysis of R-genes in plants

artículo científico publicado en 2013

PRGdb: a bioinformatics platform for plant resistance gene analysis

artículo científico publicado en 2009

PipeIT: A Singularity Container for Molecular Diagnostic Somatic Variant Calling on the Ion Torrent Next-Generation Sequencing Platform

scientific article published on 21 June 2019

Regulation of Human Epidermal Stem Cell Proliferation and Senescence Requires Polycomb- Dependent and -Independent Functions of Cbx4

Regulation of human epidermal stem cell proliferation and senescence requires polycomb- dependent and -independent functions of Cbx4.

artículo científico publicado en 2011

Rosiglitazone and AS601245 Decrease Cell Adhesion and Migration through Modulation of Specific Gene Expression in Human Colon Cancer Cells ⬇️

artículo científico publicado el 28 de junio de 2012

SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice

artículo científico publicado en 2015

Screening of Intestinal Crypt Organoids: A Simple Readout for Complex Biology

scholarly article published 6 January 2017

Self-organization and symmetry breaking in intestinal organoid development

scientific article published on 24 April 2019

SuperFly: a comparative database for quantified spatio-temporal gene expression patterns in early dipteran embryos

artículo científico publicado en 2014

TEQC: an R package for quality control in target capture experiments

artículo científico publicado en 2011

TORC1 inhibition enhances immune function and reduces infections in the elderly

scientific article published on 01 July 2018

TRRAP is a central regulator of human multiciliated cell formation.

artículo científico publicado en 2018

The Genetic Architecture of Carbon Tetrachloride-Induced Liver Fibrosis in Mice

scientific article published on 28 August 2020

The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.

artículo científico publicado en 2016

The UniTrap resource: tools for the biologist enabling optimized use of gene trap clones.

artículo científico publicado en 2007

The exon quantification pipeline (EQP): a comprehensive approach to the quantification of gene, exon and junction expression from RNA-seq data

artículo científico publicado en 2016

The genome of melon (Cucumis melo L.).

artículo científico publicado en 2012

The liver-specific protein 2 (LISP2) is an early marker of liver stage development

artículo científico publicado en 2019

Transcriptomic analysis reveals reduced transcriptional activity in the malaria parasite during progression into dormancy

artículo científico publicado en 2018

UTS2B Defines a Novel Enteroendocrine Cell Population and Regulates GLP-1 Secretion Through SSTR5 in Male Mice

artículo científico publicado en 2019

Widespread generation of alternative UTRs contributes to sex-specific RNA binding by UNR

artículo científico publicado en 2011

X-ray Structures and Feasibility Assessment of CLK2 Inhibitors for Phelan-McDermid Syndrome

artículo científico publicado en 2018

YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury

scientific article published on 09 May 2019

YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers

artículo científico publicado en 2015

mTORC1 signaling suppresses Wnt/β-catenin signaling through DVL-dependent regulation of Wnt receptor FZD level

article published in the Proceedings of the National Academy of Sciences of the United States of America

Lista de obras de Guglielmo Roma

A Simple and Efficient CRISPR Technique for Protein Tagging

A comparative transcriptomic analysis of replicating and dormant liver stages of the relapsing malaria parasite Plasmodium cynomolgi.

A comprehensive assessment of RNA-seq protocols for degraded and low-quantity samples

A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells

A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte

AS601245, an Anti-Inflammatory JNK Inhibitor, and Clofibrate Have a Synergistic Effect in Inducing Cell Responses and in Affecting the Gene Expression Profile in CaCo-2 Colon Cancer Cells ⬇️

AXIN2+ Pericentral Hepatocytes Have Limited Contributions to Liver Homeostasis and Regeneration

Active poly(ADPribose) metabolism in DNAase- and salt-resistant rat testis chromatin with high transcriptional activity/competence

Age-Related Gene Expression Signature in Rats Demonstrate Early, Late, and Linear Transcriptional Changes from Multiple Tissues

Age-associated inflammation inhibits epidermal stem cell function

An iron-dependent metabolic vulnerability underlies VPS34-dependence in RKO cancer cells

Author Correction: CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma

CGG Repeat-Induced FMR1 Silencing Depends on the Expansion Size in Human iPSCs and Neurons Carrying Unmethylated Full Mutations

CLK2 inhibition ameliorates autistic features associated with SHANK3 deficiency.

CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing's sarcoma

Cell Types of the Human Retina and Its Organoids at Single-Cell Resolution

CellSIUS provides sensitive and specific detection of rare cell populations from complex single cell RNA-seq data

CellSIUS provides sensitive and specific detection of rare cell populations from complex single-cell RNA-seq data

Comparative transcriptomics of early dipteran development

Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice

Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice

Corrigendum: The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size

Decatransin, a new natural product inhibiting protein translocation at the Sec61/SecYEG translocon

Discovery of a ZIP7 inhibitor from a Notch pathway screen

E-box-independent regulation of transcription and differentiation by MYC.

Extreme genomic erosion after recurrent demographic bottlenecks in the highly endangered Iberian lynx

Farnesoid X Receptor Agonism, Acetyl-Coenzyme A Carboxylase Inhibition, and Back Translation of Clinically Observed Endpoints of De Novo Lipogenesis in a Murine NASH Model

Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62

Genome-wide CRISPR screen for PARKIN regulators reveals transcriptional repression as a determinant of mitophagy

Genomic Analysis Revealed New Oncogenic Signatures in TP53-Mutant Hepatocellular Carcinoma.

Hi-Cpipe: a pipeline for high-throughput chromosome capture

HuR Small-Molecule Inhibitor Elicits Differential Effects in Adenomatosis Polyposis and Colorectal Carcinogenesis.

HumMeth27QCReport: an R package for quality control and primary analysis of Illumina Infinium methylation data

IRF2 is a master regulator of human keratinocyte stem cell fate

Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells.

Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

Identification of the C3a Receptor (C3AR1) as the Target of the VGF-derived Peptide TLQP-21 in Rodent Cells ⬇️

Immune cell landscaping reveals a protective role for regulatory T cells during kidney injury and fibrosis

Integration of multi-omics data of a genome-reduced bacterium: Prevalence of post-transcriptional regulation and its correlation with protein abundances

Lack of sik1 in mouse embryonic stem cells impairs cardiomyogenesis by down-regulating the cyclin-dependent kinase inhibitor p57kip2

Liver biopsy derived induced pluripotent stem cells provide unlimited supply for the generation of hepatocyte-like cells

MiR-210 promotes sensory hair cell formation in the organ of corti

MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae

Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells

PAX8 activates metabolic genes via enhancer elements in Renal Cell Carcinoma

PRGdb 2.0: towards a community-based database model for the analysis of R-genes in plants

PRGdb: a bioinformatics platform for plant resistance gene analysis

PipeIT: A Singularity Container for Molecular Diagnostic Somatic Variant Calling on the Ion Torrent Next-Generation Sequencing Platform

Regulation of Human Epidermal Stem Cell Proliferation and Senescence Requires Polycomb- Dependent and -Independent Functions of Cbx4

Regulation of human epidermal stem cell proliferation and senescence requires polycomb- dependent and -independent functions of Cbx4.

Rosiglitazone and AS601245 Decrease Cell Adhesion and Migration through Modulation of Specific Gene Expression in Human Colon Cancer Cells ⬇️

SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice

Screening of Intestinal Crypt Organoids: A Simple Readout for Complex Biology

Self-organization and symmetry breaking in intestinal organoid development

SuperFly: a comparative database for quantified spatio-temporal gene expression patterns in early dipteran embryos

TEQC: an R package for quality control in target capture experiments

TORC1 inhibition enhances immune function and reduces infections in the elderly

TRRAP is a central regulator of human multiciliated cell formation.

The Genetic Architecture of Carbon Tetrachloride-Induced Liver Fibrosis in Mice

The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size.

The UniTrap resource: tools for the biologist enabling optimized use of gene trap clones.

The exon quantification pipeline (EQP): a comprehensive approach to the quantification of gene, exon and junction expression from RNA-seq data

The genome of melon (Cucumis melo L.).

The liver-specific protein 2 (LISP2) is an early marker of liver stage development

Transcriptomic analysis reveals reduced transcriptional activity in the malaria parasite during progression into dormancy

UTS2B Defines a Novel Enteroendocrine Cell Population and Regulates GLP-1 Secretion Through SSTR5 in Male Mice

Widespread generation of alternative UTRs contributes to sex-specific RNA binding by UNR

X-ray Structures and Feasibility Assessment of CLK2 Inhibitors for Phelan-McDermid Syndrome

YAP, but Not RSPO-LGR4/5, Signaling in Biliary Epithelial Cells Promotes a Ductular Reaction in Response to Liver Injury

YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers

mTORC1 signaling suppresses Wnt/β-catenin signaling through DVL-dependent regulation of Wnt receptor FZD level