Lista de obras - Paolo Sportoletti - Dominio Público Uruguay

A genetic platform to model sarcomagenesis from primary adult mesenchymal stem cells

artículo científico publicado en 2015

A novel NOTCH1 PEST domain mutation in a case of chronic lymphocytic leukemia

artículo científico publicado en 2012

A revised NOTCH1 mutation frequency still impacts survival while the allele burden predicts early progression in chronic lymphocytic leukemia.

artículo científico publicado en 2013

A scale of "bad" co-mutations in NPM1-driven AML.

artículo científico publicado en 2017

Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity?

artículo científico publicado en 2010

Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells.

artículo científico publicado en 2015

BRAF inhibitors reverse the unique molecular signature and phenotype of hairy cell leukemia and exert potent antileukemic activity

artículo científico publicado en 2014

BRAF mutations in hairy-cell leukemia

artículo científico publicado en 2011

Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice

artículo científico publicado en 2020

CD4(+) CD25(low) GITR(+) cells: a novel human CD4(+) T-cell population with regulatory activity.

artículo científico publicado en 2011

COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus

artículo científico publicado en 2020

Constitutive phosphorylation of the active Notch1 intracellular domain in chronic lymphocytic leukemia cells with NOTCH1 mutation.

artículo científico publicado en 2014

GATA1 epigenetic deregulation contributes to the development of AML with NPM1 and FLT3-ITD cooperating mutations

scientific article published on 12 February 2019

Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita

artículo científico publicado en 2019

Glucocorticoid-Induced TNFR family Related gene (GITR) enhances dendritic cell activity

artículo científico publicado en 2010

How Does the NPM1 Mutant Induce Leukemia? ⬇️

artículo científico publicado el 22 de junio de 2011

Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation

artículo científico publicado en 2010

Immunoselection and clinical use of T regulatory cells in HLA-haploidentical stem cell transplantation

artículo científico publicado en 2011

Interleukin-7-engineered mesenchymal cells: in vitro effects on naive T-cell population.

artículo científico publicado en 2006

Lack of glucocorticoid-induced leucine zipper (GILZ) deregulates B-cell survival and results in B-cell lymphocytosis in mice.

artículo científico publicado en 2015

Loss of bone mineral density and secondary hyperparathyroidism are complications of autologous stem cell transplantation

scientific article published on 01 May 2007

Mesenchymal cells recruit and regulate T regulatory cells

scientific article published on 01 March 2008

Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication and tumorigenesis

artículo científico publicado en 2010

Mouse models of NPM1-mutated acute myeloid leukemia: biological and clinical implications.

artículo científico publicado en 2014

Mutational landscape of AML with normal cytogenetics: biological and clinical implications.

artículo científico publicado en 2012

NOTCH and NF-κB interplay in chronic lymphocytic leukemia is independent of genetic lesion.

artículo científico publicado en 2013

NOTCH1 PEST domain mutation is an adverse prognostic factor in B-CLL

artículo científico publicado en 2010

Notch signaling sustains the expression of Mcl-1 and the activity of eIF4E to promote cell survival in CLL.

artículo científico publicado en 2015

Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction

artículo científico publicado en 2012

Npm1 is a haploinsufficient suppressor of myeloid and lymphoid malignancies in the mouse

artículo científico publicado en 2008

Perspectives for therapeutic targeting of gene mutations in acute myeloid leukaemia with normal cytogenetics.

artículo científico

Recurrent primary plasmacytoma of the eyelid with rapid regional metastasis

artículo científico publicado en 2006

Survival risk score for real-life relapsed/refractory chronic lymphocytic leukemia patients receiving ibrutinib. A campus CLL study

scientific article published on 14 April 2020

T regulatory cell separation for clinical application.

artículo científico

The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model

artículo científico publicado en 2009

The human NPM1 mutation A perturbs megakaryopoiesis in a conditional mouse model.

artículo científico publicado en 2013

The leukemia-associated cytoplasmic nucleophosmin mutant is an oncogene with paradoxical functions: Arf inactivation and induction of cellular senescence.

artículo científico publicado en 2007

Uncommon lymphoplasmacytic lymphoma with IgA paraproteinemia: a challenging clinical diagnosis solved by MYD88 mutation analysis

scientific article published on 13 November 2018

Up-regulation of translation eukaryotic initiation factor 4E in nucleophosmin 1 haploinsufficient cells results in changes in CCAAT enhancer-binding protein α activity: implications in myelodysplastic syndrome and acute myeloid leukemia.

artículo científico publicado en 2012

Wnt/β-Catenin Signaling Induces Integrin α4β1 in T Cells and Promotes a Progressive Neuroinflammatory Disease in Mice.

artículo científico publicado en 2017

Lista de obras de Paolo Sportoletti

A genetic platform to model sarcomagenesis from primary adult mesenchymal stem cells

A novel NOTCH1 PEST domain mutation in a case of chronic lymphocytic leukemia

A revised NOTCH1 mutation frequency still impacts survival while the allele burden predicts early progression in chronic lymphocytic leukemia.

A scale of "bad" co-mutations in NPM1-driven AML.

Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity?

Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells.

BRAF inhibitors reverse the unique molecular signature and phenotype of hairy cell leukemia and exert potent antileukemic activity

BRAF mutations in hairy-cell leukemia

Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice

CD4(+) CD25(low) GITR(+) cells: a novel human CD4(+) T-cell population with regulatory activity.

COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus

Constitutive phosphorylation of the active Notch1 intracellular domain in chronic lymphocytic leukemia cells with NOTCH1 mutation.

GATA1 epigenetic deregulation contributes to the development of AML with NPM1 and FLT3-ITD cooperating mutations

Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita

Glucocorticoid-Induced TNFR family Related gene (GITR) enhances dendritic cell activity

How Does the NPM1 Mutant Induce Leukemia? ⬇️

Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation

Immunoselection and clinical use of T regulatory cells in HLA-haploidentical stem cell transplantation

Interleukin-7-engineered mesenchymal cells: in vitro effects on naive T-cell population.

Lack of glucocorticoid-induced leucine zipper (GILZ) deregulates B-cell survival and results in B-cell lymphocytosis in mice.

Loss of bone mineral density and secondary hyperparathyroidism are complications of autologous stem cell transplantation

Mesenchymal cells recruit and regulate T regulatory cells

Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication and tumorigenesis

Mouse models of NPM1-mutated acute myeloid leukemia: biological and clinical implications.

Mutational landscape of AML with normal cytogenetics: biological and clinical implications.

NOTCH and NF-κB interplay in chronic lymphocytic leukemia is independent of genetic lesion.

NOTCH1 PEST domain mutation is an adverse prognostic factor in B-CLL

Notch signaling sustains the expression of Mcl-1 and the activity of eIF4E to promote cell survival in CLL.

Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction

Npm1 is a haploinsufficient suppressor of myeloid and lymphoid malignancies in the mouse

Perspectives for therapeutic targeting of gene mutations in acute myeloid leukaemia with normal cytogenetics.

Recurrent primary plasmacytoma of the eyelid with rapid regional metastasis

Survival risk score for real-life relapsed/refractory chronic lymphocytic leukemia patients receiving ibrutinib. A campus CLL study

T regulatory cell separation for clinical application.

The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model

The human NPM1 mutation A perturbs megakaryopoiesis in a conditional mouse model.

The leukemia-associated cytoplasmic nucleophosmin mutant is an oncogene with paradoxical functions: Arf inactivation and induction of cellular senescence.

Uncommon lymphoplasmacytic lymphoma with IgA paraproteinemia: a challenging clinical diagnosis solved by MYD88 mutation analysis

Up-regulation of translation eukaryotic initiation factor 4E in nucleophosmin 1 haploinsufficient cells results in changes in CCAAT enhancer-binding protein α activity: implications in myelodysplastic syndrome and acute myeloid leukemia.

Wnt/β-Catenin Signaling Induces Integrin α4β1 in T Cells and Promotes a Progressive Neuroinflammatory Disease in Mice.