Lista de obras - Vincenzo Calderone - Dominio Público Uruguay

(+/-)-Naringenin as large conductance Ca(2+)-activated K+ (BKCa) channel opener in vascular smooth muscle cells

artículo científico publicado en 2006

1,2,3-Triazol-carboxanilides and 1,2,3-triazol-(N-benzyl)-carboxamides as BK-potassium channel activators. XII.

artículo científico publicado en 2008

1,4- and 2,4-substituted-1,2,3-triazoles as potential potassium channel activators. VII.

artículo científico publicado en 2005

1,4-Benzothiazine ATP-sensitive potassium channel openers: modifications at the C-2 and C-6 positions

artículo científico publicado en 2013

1,5-Diarylsubstituted 1,2,3-triazoles as potassium channel activators. VI.

artículo científico publicado en 2004

5-(4′-Substituted-2′-nitroanilino)-1,2,3-triazoles as new potential potassium channel activators. I

artículo científico publicado en 2000

A Series of COX-2 Inhibitors Endowed with NO-Releasing Properties: Synthesis, Biological Evaluation, and Docking Analysis

scientific article published on 27 May 2016

A modified aortic multiple-ring preparation for functional studies

artículo científico publicado en 1996

A simplified empirical approach to evaluate the dissociation constant of a full agonist by the irreversible receptor inactivation method.

artículo científico publicado en 1998

An alternative method to evaluate the nature of an antagonist and its potency: a theoretical approach.

artículo científico publicado en 1998

An update on hybrid drugs in cardiovascular drug research ⬇️

artículo científico publicado el 1 de diciembre de 2008

Anti-ischaemic activity of an antioxidant aldose reductase inhibitor on diabetic and non-diabetic rat hearts

artículo científico publicado en 2010

Anti-ischemic properties of a new spiro-cyclic benzopyran activator of the cardiac mito-KATP channel

artículo científico publicado en 2009

Antioxidant and Antisenescence Effects of Bergamot Juice

artículo científico publicado en 2018

Arylthioamides as H2S Donors: l-Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo

artículo científico publicado en 2013

Benzoyl and/or benzyl substituted 1,2,3-triazoles as potassium channel activators. VIII.

artículo científico publicado en 2005

Cardioprotective effects of different flavonoids against myocardial ischaemia/reperfusion injury in Langendorff-perfused rat hearts

artículo científico publicado en 2013

Cardiovascular effects of Urtica dioica L. (Urticaceae) roots extracts: in vitro and in vivo pharmacological studies

artículo científico publicado en 2002

Conformationally restrained analogues of sympathomimetic catecholamines. Synthesis and adrenergic activity of 5,6- and 6,7-dihydroxy-3,4-dihydrospiro[naphthalen-1(2H)-2',5'-morpholines].

artículo científico publicado en 2002

Correction to Novel Analgesic/Anti-Inflammatory Agents: 1,5-Diarylpyrrole Nitrooxyalkyl Ethers and Related Compounds as Cyclooxygenase-2 Inhibiting Nitric Oxide Donors

Cystathionine β-synthase-derived hydrogen sulfide is involved in human malignant hyperthermia.

artículo científico publicado en 2015

D-Penicillamine modulates hydrogen sulfide (H2S) pathway through selective inhibition of cystathionine-γ-lyase

artículo científico publicado en 2016

Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme

artículo científico publicado en 2015

Different patterns of H2S/NO activity and cross-talk in the control of the coronary vascular bed under normotensive or hypertensive conditions

artículo científico publicado en 2015

Different patterns of H2S/NO cross-talk in the control of the coronary vascular bed under normotensive or hypertensive conditions

Differential effects of fondaparinux and bemiparin on angiogenic and vasculogenesis-like processes

artículo científico publicado en 2012

Drug-induced block of cardiac HERG potassium channels and development of torsade de pointes arrhythmias: the case of antipsychotics

artículo científico publicado en 2005

Editorial [Hot Topic: Potassium Channels (Guest Editor: Dr. Vincenzo Calderone)]

Effects of KATPopeners on the QT prolongation induced by HERG-blocking drugs in guinea-pigs

Efficacy of isothiocyanate-based compounds on different forms of persistent pain

Enantioselectivity in Cardioprotection induced by (S)- (−)-2,2-Dimethyl-N-(4′-acetamido-benzyl)-4-spiromorpholone-chromane

artículo científico publicado en 2009

Enhancing the pharmacodynamic profile of a class of selective COX-2 inhibiting nitric oxide donors

artículo científico publicado en 2013

Eruca sativa Mill. seed extract promotes anti-obesity and hypoglycemic effects in mice fed with a high-fat diet

artículo científico publicado en 2020

Erucin exhibits vasorelaxing effects and antihypertensive activity by H2 S-releasing properties

scientific article published on 15 April 2019

Evaluation of the NO-releasing properties of NO-donor linkers

artículo científico publicado en 2008

Experimental and theoretical comparisons between the classical Schild analysis and a new alternative method to evaluate the p A 2 of competitive antagonists

artículo científico publicado en 1999

Expression and function of Kv7.4 channels in rat cardiac mitochondria: possible targets for cardioprotection.

artículo científico publicado en 2015

Functional contribution of the endothelial component to the vasorelaxing effect of resveratrol and NS 1619, activators of the large-conductance calcium-activated potassium channels

artículo científico publicado en 2007

Heterocyclic analogs of benzanilide derivatives as potassium channel activators. IX.

artículo científico publicado en 2006

Highly Potent 1,4-Benzo-thiazine Derivatives as KATP-Channel Openers

Highly potent 1,4-benzothiazine derivatives as K(ATP)-channel openers

artículo científico publicado en 2003

Hormonal influence on the release of endothelial nitric oxide: gender-related dimorphic sensitivity of rat aorta for noradrenaline

artículo científico publicado en 2002

Hydrogen Sulphide: Biopharmacological Roles in the Cardiovascular System and Pharmaceutical Perspectives ⬇️

artículo científico publicado el 1 de enero de 2012

Hydrogen sulfide accounts for the peripheral vascular effects of zofenopril independently of ACE inhibition.

artículo científico publicado en 2014

Hydrogen sulfide inhalation ameliorates allergen induced airway hypereactivity by modulating mast cell activation

artículo científico publicado en 2015

Hydrogen sulfide releasing capacity of natural isothiocyanates: is it a reliable explanation for the multiple biological effects of Brassicaceae?

artículo científico publicado en 2014

Hydrogen sulphide: novel opportunity for drug discovery

artículo científico

Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation

Improving the solubility of a new class of antiinflammatory pharmacodynamic hybrids, that release nitric oxide and inhibit cycloxygenase-2 isoenzyme

artículo científico publicado en 2012

In vivo adenosine A2B receptor desensitization in guinea-pig airway smooth muscle: Implications for asthma

artículo científico publicado en 2007

Influence of depolarization on vasorelaxant potency and efficacy of Ca2+ entry blockers, K+ channel openers, nitrate derivatives, salbutamol and papaverine in rat aortic rings

artículo científico publicado en 1998

Inhibitors of the renal outer medullary potassium channel: a patent review

artículo científico

Intrinsic activity and EC50: the simplest tools for the evaluation of the dissociation constant of a partial agonist

scientific article published on 01 November 1998

Isothiocyanates and inhibition of mast cell degranulation: Is hydrogen sulfide the real player?

article published in 2015

Large conductance Ca(2+)-activated K(+) channel (BKCa) activating properties of a series of novel N-arylbenzamides: Channel subunit dependent effects.

artículo científico publicado en 2013

Mitochondrial potassium channels as pharmacological target for cardioprotective drugs.

artículo científico publicado en 2014

Morphiceptin analogues containing a dipeptide mimetic structure: an investigation on the bioactive topology at the mu-receptor

artículo científico publicado en 2005

N6-1,3-diphenylurea derivatives of 2-phenyl-9-benzyladenines and 8-azaadenines: synthesis and biological evaluation as allosteric modulators of A2A adenosine receptors

artículo científico publicado en 2007

NO-glibenclamide derivatives: prototypes of a new class of nitric oxide-releasing anti-diabetic drugs.

artículo científico publicado en 2009

NO-sartans: a new class of pharmacodynamic hybrids as cardiovascular drugs

artículo científico publicado en 2004

NSAID-induced enteropathy: are the currently available selective COX-2 inhibitors all the same?

artículo científico publicado en 2013

Natural modulators of large-conductance calcium-activated potassium channels

artículo científico publicado en 2003

New 5-substituted-1-(2-hydroxybenzoyl)-benzotriazoles, potassium channel activators. IV.

artículo científico publicado en 2001

New Benzopyran-Based Openers of the Mitochondrial ATP-Sensitive Potassium Channel with Potent Anti-Ischemic Properties

artículo científico publicado en 2006

New NO-Releasing Pharmacodynamic Hybrids of Losartan and Its Active Metabolite: Design, Synthesis, and Biopharmacological Properties

artículo científico publicado en 2006

New amido derivatives as potential BKCa potassium channel activators. XI

artículo científico publicado en 2007

New emerging prospects in the pharmacotherapy of hypertension.

artículo científico publicado en 2008

Novel 1,4-benzothiazine derivatives as large conductance Ca2+-activated potassium channel openers

artículo científico publicado en 2008

Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1/L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands

artículo científico publicado en 2007

Novel analgesic/anti-inflammatory agents: 1,5-diarylpyrrole nitrooxyalkyl ethers and related compounds as cyclooxygenase-2 inhibiting nitric oxide donors

artículo científico publicado en 2013

Novel analgesic/anti-inflammatory agents: diarylpyrrole acetic esters endowed with nitric oxide releasing properties

artículo científico publicado en 2011

Off-target ACE2 ligands: possible therapeutic option for CoVid-19?

scientific article published on 02 May 2020

Pharmacodynamic hybrids coupling established cardiovascular mechanisms of action with additional nitric oxide releasing properties

artículo científico publicado en 2009

Pharmacological characterization of the vascular effects of aryl isothiocyanates: is hydrogen sulfide the real player?

artículo científico publicado en 2013

Pharmacological modulation of the hydrogen sulfide (H2 S) system by dietary H2 S-donors: A novel promising strategy in the prevention and treatment of type 2 diabetes mellitus

scientific article published on 29 October 2020

Prediction of hERG potassium channel affinity by the CODESSA approach

artículo científico publicado en 2006

Predictive models, based on classification algorithms, for compounds potentially active as mitochondrial ATP-sensitive potassium channel openers

artículo científico publicado en 2009

Proposal of a New Binding Orientation for Non-Peptide AT1 Antagonists: Homology Modeling, Docking and Three-Dimensional Quantitative Structure−Activity Relationship Analysis

article

Protective effect of high-dose montelukast on salbutamol-induced homologous desensitisation in airway smooth muscle

artículo científico publicado en 2013

QSAR studies on BK channel activators

artículo científico publicado en 2008

QT prolongation in anaesthetized guinea-pigs: an experimental approach for preliminary screening of torsadogenicity of drugs and drug candidates.

artículo científico publicado en 2004

Quantitative structure-activity relationship models for predicting biological properties, developed by combining structure- and ligand-based approaches: an application to the human ether-a-go-go-related gene potassium channel inhibition

artículo científico publicado en 2009

R+-methanandamide inhibits tracheal response to endogenously released acetylcholine via capsazepine-sensitive receptors

artículo científico publicado en 2003

Some structural changes on triazolyl-benzotriazoles and triazolyl-benzimidazolones as potential potassium channel activators. III.

artículo científico publicado en 2001

Spirocyclic benzopyran-based derivatives as new anti-ischemic activators of mitochondrial ATP-sensitive potassium channel

artículo científico publicado en 2008

Structural modifications of benzanilide derivatives, effective potassium channel openers. X

Synthesis and beta-blocking activity of (R,S)-(E)-oximeethers of 2,3-dihydro-1,8-naphthyridine and 2,3-dihydrothiopyrano[2,3-b]pyridine: identification of beta 3-antagonists

artículo científico publicado en 2003

Synthesis and biological activity of novel substituted benzanilides as potassium channel activators. V.

artículo científico publicado en 2004

Synthesis and biological evaluation of 1,8-naphthyridin-4(1H)-on-3-carboxamide derivatives as new ligands of cannabinoid receptors

artículo científico publicado en 2004

Synthesis and biological evaluation of 5-membered spiro heterocycle-benzopyran derivatives against myocardial ischemia

artículo científico publicado en 2011

Synthesis and evaluation of antihypertensive activity of 1,8-naphthyridine derivatives. Part X.

artículo científico publicado en 2001

Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications

artículo científico publicado en 2014

Synthesis and α-adrenergic and I1-imidazoline activity of 3-phenylpiperidines dimethyl-substituted on the phenyl ring

Synthesis and β-blocking activity of (R,S)-(E)-oximeethers of 2,3-dihydro-1,8-naphthyridine and 2,3-dihydrothiopyrano[2,3-b]pyridine:potential antihypertensive agents – Part IX

scientific article published on 01 September 2000

Synthesis of 1,8-naphthyridine derivatives: Potential antihypertensive agents — Part VII

Synthesis of 1,8-naphthyridine derivatives: potential antihypertensive agents – Part VIII

Synthesis of heterocycle-based analogs of resveratrol and their antitumor and vasorelaxing properties

artículo científico publicado en 2010

The Citrus Flavanone Naringenin Protects Myocardial Cells against Age-Associated Damage.

artículo científico publicado en 2017

The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1

scientific article published on 25 January 2020

The activation of mitochondrial BK potassium channels contributes to the protective effects of naringenin against myocardial ischemia/reperfusion injury.

artículo científico publicado en 2013

The novel H2 S donor 4-carboxy-phenyl isothiocyanate inhibits mast cell degranulation and renin release by decreasing intracellular calcium.

artículo científico publicado en 2016

The novel H2S-donor 4-carboxyphenyl isothiocyanate promotes cardioprotective effects against ischemia/reperfusion injury through activation of mitoKATP channels and reduction of oxidative stress

artículo científico publicado en 2016

The novel anti-inflammatory agent VA694, endowed with both NO-releasing and COX2-selective inhibiting properties, exhibits NO-mediated positive effects on blood pressure, coronary flow and endothelium in an experimental model of hypertension and end

artículo científico publicado en 2013

The xanthones gentiacaulein and gentiakochianin are responsible for the vasodilator action of the roots of Gentiana kochiana

artículo científico publicado en 2003

Triazolyl–benzimidazolones and triazolyl–benzotriazoles: new potential potassium channel activators. II

artículo científico publicado en 2000

Using hydrogen sulfide to design and develop drugs

artículo científico publicado en 2015

Vasodilator activity of Michelia figo Spreng. (Magnoliaceae) by in vitro functional study

artículo científico publicado en 2004

Vasodilator activity of crude methanolic extract of Gentiana kokiana Perr. et Song. (Gentianaceae).

artículo científico publicado en 2002

Vasorelaxation by hydrogen sulphide involves activation of Kv7 potassium channels.

artículo científico publicado en 2013

Vasorelaxing effects of flavonoids: investigation on the possible involvement of potassium channels

artículo científico publicado en 2004

Voltage-operated potassium (Kv) channels contribute to endothelium-dependent vasorelaxation of carvacrol on rat aorta

artículo científico publicado en 2016

Lista de obras de Vincenzo Calderone

(+/-)-Naringenin as large conductance Ca(2+)-activated K+ (BKCa) channel opener in vascular smooth muscle cells

1,2,3-Triazol-carboxanilides and 1,2,3-triazol-(N-benzyl)-carboxamides as BK-potassium channel activators. XII.

1,4- and 2,4-substituted-1,2,3-triazoles as potential potassium channel activators. VII.

1,4-Benzothiazine ATP-sensitive potassium channel openers: modifications at the C-2 and C-6 positions

1,5-Diarylsubstituted 1,2,3-triazoles as potassium channel activators. VI.

5-(4′-Substituted-2′-nitroanilino)-1,2,3-triazoles as new potential potassium channel activators. I

A Series of COX-2 Inhibitors Endowed with NO-Releasing Properties: Synthesis, Biological Evaluation, and Docking Analysis

A modified aortic multiple-ring preparation for functional studies

A simplified empirical approach to evaluate the dissociation constant of a full agonist by the irreversible receptor inactivation method.

An alternative method to evaluate the nature of an antagonist and its potency: a theoretical approach.

An update on hybrid drugs in cardiovascular drug research ⬇️

Anti-ischaemic activity of an antioxidant aldose reductase inhibitor on diabetic and non-diabetic rat hearts

Anti-ischemic properties of a new spiro-cyclic benzopyran activator of the cardiac mito-KATP channel

Antioxidant and Antisenescence Effects of Bergamot Juice

Arylthioamides as H2S Donors: l-Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo

Benzoyl and/or benzyl substituted 1,2,3-triazoles as potassium channel activators. VIII.

Cardioprotective effects of different flavonoids against myocardial ischaemia/reperfusion injury in Langendorff-perfused rat hearts

Cardiovascular effects of Urtica dioica L. (Urticaceae) roots extracts: in vitro and in vivo pharmacological studies

Conformationally restrained analogues of sympathomimetic catecholamines. Synthesis and adrenergic activity of 5,6- and 6,7-dihydroxy-3,4-dihydrospiro[naphthalen-1(2H)-2',5'-morpholines].

Correction to Novel Analgesic/Anti-Inflammatory Agents: 1,5-Diarylpyrrole Nitrooxyalkyl Ethers and Related Compounds as Cyclooxygenase-2 Inhibiting Nitric Oxide Donors

Cystathionine β-synthase-derived hydrogen sulfide is involved in human malignant hyperthermia.

D-Penicillamine modulates hydrogen sulfide (H2S) pathway through selective inhibition of cystathionine-γ-lyase

Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme

Different patterns of H2S/NO activity and cross-talk in the control of the coronary vascular bed under normotensive or hypertensive conditions

Different patterns of H2S/NO cross-talk in the control of the coronary vascular bed under normotensive or hypertensive conditions

Differential effects of fondaparinux and bemiparin on angiogenic and vasculogenesis-like processes

Drug-induced block of cardiac HERG potassium channels and development of torsade de pointes arrhythmias: the case of antipsychotics

Editorial [Hot Topic: Potassium Channels (Guest Editor: Dr. Vincenzo Calderone)]

Effects of KATPopeners on the QT prolongation induced by HERG-blocking drugs in guinea-pigs

Efficacy of isothiocyanate-based compounds on different forms of persistent pain

Enantioselectivity in Cardioprotection induced by (S)- (−)-2,2-Dimethyl-N-(4′-acetamido-benzyl)-4-spiromorpholone-chromane

Enhancing the pharmacodynamic profile of a class of selective COX-2 inhibiting nitric oxide donors

Eruca sativa Mill. seed extract promotes anti-obesity and hypoglycemic effects in mice fed with a high-fat diet

Erucin exhibits vasorelaxing effects and antihypertensive activity by H2 S-releasing properties

Evaluation of the NO-releasing properties of NO-donor linkers

Experimental and theoretical comparisons between the classical Schild analysis and a new alternative method to evaluate the p A 2 of competitive antagonists

Expression and function of Kv7.4 channels in rat cardiac mitochondria: possible targets for cardioprotection.

Functional contribution of the endothelial component to the vasorelaxing effect of resveratrol and NS 1619, activators of the large-conductance calcium-activated potassium channels

Heterocyclic analogs of benzanilide derivatives as potassium channel activators. IX.

Highly Potent 1,4-Benzo-thiazine Derivatives as KATP-Channel Openers

Highly potent 1,4-benzothiazine derivatives as K(ATP)-channel openers

Hormonal influence on the release of endothelial nitric oxide: gender-related dimorphic sensitivity of rat aorta for noradrenaline

Hydrogen Sulphide: Biopharmacological Roles in the Cardiovascular System and Pharmaceutical Perspectives ⬇️

Hydrogen sulfide accounts for the peripheral vascular effects of zofenopril independently of ACE inhibition.

Hydrogen sulfide inhalation ameliorates allergen induced airway hypereactivity by modulating mast cell activation

Hydrogen sulfide releasing capacity of natural isothiocyanates: is it a reliable explanation for the multiple biological effects of Brassicaceae?

Hydrogen sulphide: novel opportunity for drug discovery

Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation

Improving the solubility of a new class of antiinflammatory pharmacodynamic hybrids, that release nitric oxide and inhibit cycloxygenase-2 isoenzyme

In vivo adenosine A2B receptor desensitization in guinea-pig airway smooth muscle: Implications for asthma

Influence of depolarization on vasorelaxant potency and efficacy of Ca2+ entry blockers, K+ channel openers, nitrate derivatives, salbutamol and papaverine in rat aortic rings

Inhibitors of the renal outer medullary potassium channel: a patent review

Intrinsic activity and EC50: the simplest tools for the evaluation of the dissociation constant of a partial agonist

Isothiocyanates and inhibition of mast cell degranulation: Is hydrogen sulfide the real player?

Large conductance Ca(2+)-activated K(+) channel (BKCa) activating properties of a series of novel N-arylbenzamides: Channel subunit dependent effects.

Mitochondrial potassium channels as pharmacological target for cardioprotective drugs.

Morphiceptin analogues containing a dipeptide mimetic structure: an investigation on the bioactive topology at the mu-receptor

N6-1,3-diphenylurea derivatives of 2-phenyl-9-benzyladenines and 8-azaadenines: synthesis and biological evaluation as allosteric modulators of A2A adenosine receptors

NO-glibenclamide derivatives: prototypes of a new class of nitric oxide-releasing anti-diabetic drugs.

NO-sartans: a new class of pharmacodynamic hybrids as cardiovascular drugs

NSAID-induced enteropathy: are the currently available selective COX-2 inhibitors all the same?

Natural modulators of large-conductance calcium-activated potassium channels

New 5-substituted-1-(2-hydroxybenzoyl)-benzotriazoles, potassium channel activators. IV.

New Benzopyran-Based Openers of the Mitochondrial ATP-Sensitive Potassium Channel with Potent Anti-Ischemic Properties

New NO-Releasing Pharmacodynamic Hybrids of Losartan and Its Active Metabolite: Design, Synthesis, and Biopharmacological Properties

New amido derivatives as potential BKCa potassium channel activators. XI

New emerging prospects in the pharmacotherapy of hypertension.

Novel 1,4-benzothiazine derivatives as large conductance Ca2+-activated potassium channel openers

Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1/L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands

Novel analgesic/anti-inflammatory agents: 1,5-diarylpyrrole nitrooxyalkyl ethers and related compounds as cyclooxygenase-2 inhibiting nitric oxide donors

Novel analgesic/anti-inflammatory agents: diarylpyrrole acetic esters endowed with nitric oxide releasing properties

Off-target ACE2 ligands: possible therapeutic option for CoVid-19?

Pharmacodynamic hybrids coupling established cardiovascular mechanisms of action with additional nitric oxide releasing properties

Pharmacological characterization of the vascular effects of aryl isothiocyanates: is hydrogen sulfide the real player?

Pharmacological modulation of the hydrogen sulfide (H2 S) system by dietary H2 S-donors: A novel promising strategy in the prevention and treatment of type 2 diabetes mellitus

Prediction of hERG potassium channel affinity by the CODESSA approach

Predictive models, based on classification algorithms, for compounds potentially active as mitochondrial ATP-sensitive potassium channel openers

Proposal of a New Binding Orientation for Non-Peptide AT1 Antagonists: Homology Modeling, Docking and Three-Dimensional Quantitative Structure−Activity Relationship Analysis

Protective effect of high-dose montelukast on salbutamol-induced homologous desensitisation in airway smooth muscle