Lista de obras - Lara Testai - Dominio Público Uruguay

(+/-)-Naringenin as large conductance Ca(2+)-activated K+ (BKCa) channel opener in vascular smooth muscle cells

artículo científico publicado en 2006

1,4-Benzothiazine ATP-sensitive potassium channel openers: modifications at the C-2 and C-6 positions

artículo científico publicado en 2013

A New Calcium Oral Controlled-Release System Based on Zeolite for Prevention of Osteoporosis

scientific article published on 15 October 2019

A Nutraceutical Strategy to Slowing Down the Progression of Cone Death in an Animal Model of Retinitis Pigmentosa

scientific article published on 17 May 2019

Anti-ischaemic activity of an antioxidant aldose reductase inhibitor on diabetic and non-diabetic rat hearts

artículo científico publicado en 2010

Anti-ischemic properties of a new spiro-cyclic benzopyran activator of the cardiac mito-KATP channel

artículo científico publicado en 2009

Anticancer properties of erucin, an H2 S-releasing isothiocyanate, on human pancreatic adenocarcinoma cells (AsPC-1)

artículo científico publicado en 2019

Antioxidant and Antisenescence Effects of Bergamot Juice

artículo científico publicado en 2018

Arylthioamides as H2S Donors: l-Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo

artículo científico publicado en 2013

By-Products from Winemaking and Olive Mill Value Chains for the Enrichment of Refined Olive Oil: Technological Challenges and Nutraceutical Features

artículo científico publicado en 2020

Cardioprotective effects of different flavonoids against myocardial ischaemia/reperfusion injury in Langendorff-perfused rat hearts

artículo científico publicado en 2013

Cardiovascular effects of Urtica dioica L. (Urticaceae) roots extracts: in vitro and in vivo pharmacological studies

artículo científico publicado en 2002

Coenzyme Q10: Clinical Applications in Cardiovascular Diseases

scientific article published on 22 April 2020

Correction to Novel Analgesic/Anti-Inflammatory Agents: 1,5-Diarylpyrrole Nitrooxyalkyl Ethers and Related Compounds as Cyclooxygenase-2 Inhibiting Nitric Oxide Donors

Different patterns of H2S/NO activity and cross-talk in the control of the coronary vascular bed under normotensive or hypertensive conditions

artículo científico publicado en 2015

Drug-induced block of cardiac HERG potassium channels and development of torsade de pointes arrhythmias: the case of antipsychotics

artículo científico publicado en 2005

Effect of glucoraphanin and sulforaphane against chemotherapy-induced neuropathic pain: Kv7 potassium channels modulation by H S release in vivo

artículo científico publicado en 2018

Effects of cannabinoids on non-adrenergic non-cholinergic-mediated relaxation in guinea-pig trachea

artículo científico publicado en 2003

Efficacy of isothiocyanate-based compounds on different forms of persistent pain

Enantioselectivity in Cardioprotection induced by (S)- (−)-2,2-Dimethyl-N-(4′-acetamido-benzyl)-4-spiromorpholone-chromane

artículo científico publicado en 2009

Enhancing the pharmacodynamic profile of a class of selective COX-2 inhibiting nitric oxide donors

artículo científico publicado en 2013

Eruca sativa Meal against Diabetic Neuropathic Pain: An H2S-Mediated Effect of Glucoerucin

artículo científico publicado en 2019

Eruca sativa Mill. seed extract promotes anti-obesity and hypoglycemic effects in mice fed with a high-fat diet

artículo científico publicado en 2020

Erucin exhibits vasorelaxing effects and antihypertensive activity by H2 S-releasing properties

scientific article published on 15 April 2019

Evaluation of the NO-releasing properties of NO-donor linkers

artículo científico publicado en 2008

Ex Vivo and in Vivo Study of Sucrosomial Iron Intestinal Absorption and Bioavailability

scientific article published on 12 September 2018

Flavonoids and mitochondrial pharmacology: A new paradigm for cardioprotection

artículo científico

Functional contribution of the endothelial component to the vasorelaxing effect of resveratrol and NS 1619, activators of the large-conductance calcium-activated potassium channels

artículo científico publicado en 2007

Highly Potent 1,4-Benzo-thiazine Derivatives as KATP-Channel Openers

Highly potent 1,4-benzothiazine derivatives as K(ATP)-channel openers

artículo científico publicado en 2003

Hydrogen Sulphide: Biopharmacological Roles in the Cardiovascular System and Pharmaceutical Perspectives ⬇️

artículo científico publicado el 1 de enero de 2012

Hydrogen sulfide releasing capacity of natural isothiocyanates: is it a reliable explanation for the multiple biological effects of Brassicaceae?

artículo científico publicado en 2014

Hydrogen sulphide: novel opportunity for drug discovery

artículo científico

Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation

Iminothioethers as Hydrogen Sulfide Donors: From the Gasotransmitter Release to the Vascular Effects.

artículo científico publicado en 2017

Impact of mucoadhesive polymeric nanoparticulate systems on oral bioavailability of a macromolecular model drug

scientific article published on 10 July 2018

Improving the solubility of a new class of antiinflammatory pharmacodynamic hybrids, that release nitric oxide and inhibit cycloxygenase-2 isoenzyme

artículo científico publicado en 2012

Inhibitors of the renal outer medullary potassium channel: a patent review

artículo científico

Innovative Strategies for Cardioprotection

artículo científico publicado en 2018

Matrix metalloproteinase-12 inhibitors: synthesis, structure-activity relationships and intestinal absorption of novel sugar-based biphenylsulfonamide carboxylates

artículo científico publicado en 2018

Mitochondrial potassium channels as pharmacological target for cardioprotective drugs.

artículo científico publicado en 2014

Mitochondriotropic and Cardioprotective Effects of Triphenylphosphonium-Conjugated Derivatives of the Diterpenoid Isosteviol.

artículo científico publicado en 2017

NO-glibenclamide derivatives: prototypes of a new class of nitric oxide-releasing anti-diabetic drugs.

artículo científico publicado en 2009

NSAID-induced enteropathy: are the currently available selective COX-2 inhibitors all the same?

artículo científico publicado en 2013

New Benzopyran-Based Openers of the Mitochondrial ATP-Sensitive Potassium Channel with Potent Anti-Ischemic Properties

artículo científico publicado en 2006

New NO-Releasing Pharmacodynamic Hybrids of Losartan and Its Active Metabolite: Design, Synthesis, and Biopharmacological Properties

artículo científico publicado en 2006

Novel 1,4-benzothiazine derivatives as large conductance Ca2+-activated potassium channel openers

artículo científico publicado en 2008

Novel analgesic/anti-inflammatory agents: 1,5-diarylpyrrole nitrooxyalkyl ethers and related compounds as cyclooxygenase-2 inhibiting nitric oxide donors

artículo científico publicado en 2013

Novel analgesic/anti-inflammatory agents: diarylpyrrole acetic esters endowed with nitric oxide releasing properties

artículo científico publicado en 2011

Nutraceutical Value of Citrus Flavanones and Their Implications in Cardiovascular Disease

artículo científico publicado en 2017

Organic Isothiocyanates as Hydrogen Sulfide Donors

scientific article published on 20 November 2019

Pathophysiological role of mitochondrial potassium channels and their modulation by drugs.

artículo científico publicado en 2017

Pharmacological characterization of the vascular effects of aryl isothiocyanates: is hydrogen sulfide the real player?

artículo científico publicado en 2013

Predictive models, based on classification algorithms, for compounds potentially active as mitochondrial ATP-sensitive potassium channel openers

artículo científico publicado en 2009

Protective Effects of Bergamot (Citrus bergamia Risso & Poiteau) Juice in Rats Fed with High-Fat Diet

artículo científico publicado en 2019

Protective effect of high-dose montelukast on salbutamol-induced homologous desensitisation in airway smooth muscle

artículo científico publicado en 2013

QT prolongation in anaesthetized guinea-pigs: an experimental approach for preliminary screening of torsadogenicity of drugs and drug candidates.

artículo científico publicado en 2004

Quantitative structure-activity relationship models for predicting biological properties, developed by combining structure- and ligand-based approaches: an application to the human ether-a-go-go-related gene potassium channel inhibition

artículo científico publicado en 2009

R+-methanandamide inhibits tracheal response to endogenously released acetylcholine via capsazepine-sensitive receptors

artículo científico publicado en 2003

Spirocyclic benzopyran-based derivatives as new anti-ischemic activators of mitochondrial ATP-sensitive potassium channel

artículo científico publicado en 2008

Supplementation of Enriched Polyunsaturated Fatty Acids and CLA Cheese on High Fat Diet: Effects on Lipid Metabolism and Fat Profile

artículo científico publicado en 2022

Synthesis and beta-blocking activity of (R,S)-(E)-oximeethers of 2,3-dihydro-1,8-naphthyridine and 2,3-dihydrothiopyrano[2,3-b]pyridine: identification of beta 3-antagonists

artículo científico publicado en 2003

Synthesis and biological evaluation of 5-membered spiro heterocycle-benzopyran derivatives against myocardial ischemia

artículo científico publicado en 2011

Synthesis and evaluation of antihypertensive activity of 1,8-naphthyridine derivatives. Part X.

artículo científico publicado en 2001

Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications

artículo científico publicado en 2014

Synthesis of heterocycle-based analogs of resveratrol and their antitumor and vasorelaxing properties

artículo científico publicado en 2010

Targeting STATs in neuroinflammation: The road less traveled!

scientific article published on 11 December 2018

The Citrus Flavanone Naringenin Produces Cardioprotective Effects in Hearts from 1 Year Old Rat, through Activation of mitoBK Channels.

artículo científico publicado en 2017

The Citrus Flavanone Naringenin Protects Myocardial Cells against Age-Associated Damage.

artículo científico publicado en 2017

The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1

scientific article published on 25 January 2020

The Nutraceutical Value of Olive Oil and Its Bioactive Constituents on the Cardiovascular System. Focusing on Main Strategies to Slow Down Its Quality Decay during Production and Storage

scientific article published on 21 August 2019

The Renal Outer Medullary Potassium channel (ROMK): an intriguing pharmacological target for an innovative class of diuretic drugs

artículo científico publicado en 2017

The activation of mitochondrial BK potassium channels contributes to the protective effects of naringenin against myocardial ischemia/reperfusion injury.

artículo científico publicado en 2013

The novel H2S-donor 4-carboxyphenyl isothiocyanate promotes cardioprotective effects against ischemia/reperfusion injury through activation of mitoKATP channels and reduction of oxidative stress

artículo científico publicado en 2016

The novel anti-inflammatory agent VA694, endowed with both NO-releasing and COX2-selective inhibiting properties, exhibits NO-mediated positive effects on blood pressure, coronary flow and endothelium in an experimental model of hypertension and end

artículo científico publicado en 2013

The role of hydrogen sulfide and H2S-donors in myocardial protection against ischemia/reperfusion injury

artículo científico publicado en 2018

The xanthones gentiacaulein and gentiakochianin are responsible for the vasodilator action of the roots of Gentiana kochiana

artículo científico publicado en 2003

Therapeutic potential of polyphenols in cardiovascular diseases: Regulation of mTOR signaling pathway

artículo científico publicado en 2020

Using hydrogen sulfide to design and develop drugs

artículo científico publicado en 2015

Vasodilator activity of Michelia figo Spreng. (Magnoliaceae) by in vitro functional study

artículo científico publicado en 2004

Vasodilator activity of crude methanolic extract of Gentiana kokiana Perr. et Song. (Gentianaceae).

artículo científico publicado en 2002

Vasorelaxant effects of the chloroformic crude extract of Bupleurum fruticosum L. (Umbelliferae) roots on rat thoracic aorta

artículo científico publicado en 2005

Vasorelaxation by hydrogen sulphide involves activation of Kv7 potassium channels.

artículo científico publicado en 2013

Vasorelaxing effects of flavonoids: investigation on the possible involvement of potassium channels

artículo científico publicado en 2004

Voltage-operated potassium (Kv) channels contribute to endothelium-dependent vasorelaxation of carvacrol on rat aorta

artículo científico publicado en 2016

Lista de obras de Lara Testai

(+/-)-Naringenin as large conductance Ca(2+)-activated K+ (BKCa) channel opener in vascular smooth muscle cells

1,4-Benzothiazine ATP-sensitive potassium channel openers: modifications at the C-2 and C-6 positions

A New Calcium Oral Controlled-Release System Based on Zeolite for Prevention of Osteoporosis

A Nutraceutical Strategy to Slowing Down the Progression of Cone Death in an Animal Model of Retinitis Pigmentosa

Anti-ischaemic activity of an antioxidant aldose reductase inhibitor on diabetic and non-diabetic rat hearts

Anti-ischemic properties of a new spiro-cyclic benzopyran activator of the cardiac mito-KATP channel

Anticancer properties of erucin, an H2 S-releasing isothiocyanate, on human pancreatic adenocarcinoma cells (AsPC-1)

Antioxidant and Antisenescence Effects of Bergamot Juice

Arylthioamides as H2S Donors: l-Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo

By-Products from Winemaking and Olive Mill Value Chains for the Enrichment of Refined Olive Oil: Technological Challenges and Nutraceutical Features

Cardioprotective effects of different flavonoids against myocardial ischaemia/reperfusion injury in Langendorff-perfused rat hearts

Cardiovascular effects of Urtica dioica L. (Urticaceae) roots extracts: in vitro and in vivo pharmacological studies

Coenzyme Q10: Clinical Applications in Cardiovascular Diseases

Correction to Novel Analgesic/Anti-Inflammatory Agents: 1,5-Diarylpyrrole Nitrooxyalkyl Ethers and Related Compounds as Cyclooxygenase-2 Inhibiting Nitric Oxide Donors

Different patterns of H2S/NO activity and cross-talk in the control of the coronary vascular bed under normotensive or hypertensive conditions

Drug-induced block of cardiac HERG potassium channels and development of torsade de pointes arrhythmias: the case of antipsychotics

Effect of glucoraphanin and sulforaphane against chemotherapy-induced neuropathic pain: Kv7 potassium channels modulation by H S release in vivo

Effects of cannabinoids on non-adrenergic non-cholinergic-mediated relaxation in guinea-pig trachea

Efficacy of isothiocyanate-based compounds on different forms of persistent pain

Enantioselectivity in Cardioprotection induced by (S)- (−)-2,2-Dimethyl-N-(4′-acetamido-benzyl)-4-spiromorpholone-chromane

Enhancing the pharmacodynamic profile of a class of selective COX-2 inhibiting nitric oxide donors

Eruca sativa Meal against Diabetic Neuropathic Pain: An H2S-Mediated Effect of Glucoerucin

Eruca sativa Mill. seed extract promotes anti-obesity and hypoglycemic effects in mice fed with a high-fat diet

Erucin exhibits vasorelaxing effects and antihypertensive activity by H2 S-releasing properties

Evaluation of the NO-releasing properties of NO-donor linkers

Ex Vivo and in Vivo Study of Sucrosomial Iron Intestinal Absorption and Bioavailability

Flavonoids and mitochondrial pharmacology: A new paradigm for cardioprotection

Functional contribution of the endothelial component to the vasorelaxing effect of resveratrol and NS 1619, activators of the large-conductance calcium-activated potassium channels

Highly Potent 1,4-Benzo-thiazine Derivatives as KATP-Channel Openers

Highly potent 1,4-benzothiazine derivatives as K(ATP)-channel openers

Hydrogen Sulphide: Biopharmacological Roles in the Cardiovascular System and Pharmaceutical Perspectives ⬇️

Hydrogen sulfide releasing capacity of natural isothiocyanates: is it a reliable explanation for the multiple biological effects of Brassicaceae?

Hydrogen sulphide: novel opportunity for drug discovery

Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation

Iminothioethers as Hydrogen Sulfide Donors: From the Gasotransmitter Release to the Vascular Effects.

Impact of mucoadhesive polymeric nanoparticulate systems on oral bioavailability of a macromolecular model drug

Improving the solubility of a new class of antiinflammatory pharmacodynamic hybrids, that release nitric oxide and inhibit cycloxygenase-2 isoenzyme

Inhibitors of the renal outer medullary potassium channel: a patent review

Innovative Strategies for Cardioprotection

Matrix metalloproteinase-12 inhibitors: synthesis, structure-activity relationships and intestinal absorption of novel sugar-based biphenylsulfonamide carboxylates

Mitochondrial potassium channels as pharmacological target for cardioprotective drugs.

Mitochondriotropic and Cardioprotective Effects of Triphenylphosphonium-Conjugated Derivatives of the Diterpenoid Isosteviol.

NO-glibenclamide derivatives: prototypes of a new class of nitric oxide-releasing anti-diabetic drugs.

NSAID-induced enteropathy: are the currently available selective COX-2 inhibitors all the same?

New Benzopyran-Based Openers of the Mitochondrial ATP-Sensitive Potassium Channel with Potent Anti-Ischemic Properties

New NO-Releasing Pharmacodynamic Hybrids of Losartan and Its Active Metabolite: Design, Synthesis, and Biopharmacological Properties

Novel 1,4-benzothiazine derivatives as large conductance Ca2+-activated potassium channel openers

Novel analgesic/anti-inflammatory agents: 1,5-diarylpyrrole nitrooxyalkyl ethers and related compounds as cyclooxygenase-2 inhibiting nitric oxide donors

Novel analgesic/anti-inflammatory agents: diarylpyrrole acetic esters endowed with nitric oxide releasing properties

Nutraceutical Value of Citrus Flavanones and Their Implications in Cardiovascular Disease

Organic Isothiocyanates as Hydrogen Sulfide Donors

Pathophysiological role of mitochondrial potassium channels and their modulation by drugs.

Pharmacological characterization of the vascular effects of aryl isothiocyanates: is hydrogen sulfide the real player?

Predictive models, based on classification algorithms, for compounds potentially active as mitochondrial ATP-sensitive potassium channel openers

Protective Effects of Bergamot (Citrus bergamia Risso & Poiteau) Juice in Rats Fed with High-Fat Diet

Protective effect of high-dose montelukast on salbutamol-induced homologous desensitisation in airway smooth muscle

QT prolongation in anaesthetized guinea-pigs: an experimental approach for preliminary screening of torsadogenicity of drugs and drug candidates.

Quantitative structure-activity relationship models for predicting biological properties, developed by combining structure- and ligand-based approaches: an application to the human ether-a-go-go-related gene potassium channel inhibition

R+-methanandamide inhibits tracheal response to endogenously released acetylcholine via capsazepine-sensitive receptors

Spirocyclic benzopyran-based derivatives as new anti-ischemic activators of mitochondrial ATP-sensitive potassium channel

Supplementation of Enriched Polyunsaturated Fatty Acids and CLA Cheese on High Fat Diet: Effects on Lipid Metabolism and Fat Profile

Synthesis and beta-blocking activity of (R,S)-(E)-oximeethers of 2,3-dihydro-1,8-naphthyridine and 2,3-dihydrothiopyrano[2,3-b]pyridine: identification of beta 3-antagonists

Synthesis and biological evaluation of 5-membered spiro heterocycle-benzopyran derivatives against myocardial ischemia

Synthesis and evaluation of antihypertensive activity of 1,8-naphthyridine derivatives. Part X.

Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications

Synthesis of heterocycle-based analogs of resveratrol and their antitumor and vasorelaxing properties

Targeting STATs in neuroinflammation: The road less traveled!

The Citrus Flavanone Naringenin Produces Cardioprotective Effects in Hearts from 1 Year Old Rat, through Activation of mitoBK Channels.

The Citrus Flavanone Naringenin Protects Myocardial Cells against Age-Associated Damage.

The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1

The Nutraceutical Value of Olive Oil and Its Bioactive Constituents on the Cardiovascular System. Focusing on Main Strategies to Slow Down Its Quality Decay during Production and Storage

The Renal Outer Medullary Potassium channel (ROMK): an intriguing pharmacological target for an innovative class of diuretic drugs

The activation of mitochondrial BK potassium channels contributes to the protective effects of naringenin against myocardial ischemia/reperfusion injury.

The novel H2S-donor 4-carboxyphenyl isothiocyanate promotes cardioprotective effects against ischemia/reperfusion injury through activation of mitoKATP channels and reduction of oxidative stress

The novel anti-inflammatory agent VA694, endowed with both NO-releasing and COX2-selective inhibiting properties, exhibits NO-mediated positive effects on blood pressure, coronary flow and endothelium in an experimental model of hypertension and end

The role of hydrogen sulfide and H2S-donors in myocardial protection against ischemia/reperfusion injury

The xanthones gentiacaulein and gentiakochianin are responsible for the vasodilator action of the roots of Gentiana kochiana

Therapeutic potential of polyphenols in cardiovascular diseases: Regulation of mTOR signaling pathway

Using hydrogen sulfide to design and develop drugs