Lista de obras - Hongbo Chi - Dominio Público Uruguay

AMPK helps T cells survive nutrient starvation

artículo científico publicado en 2015

Acetylation of MKP-1 and the control of inflammation.

artículo científico publicado en 2008

Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

artículo científico publicado en 2016

Autophagy modulates CD4+ T-cell lineage recommitment upon pathogen infection

scientific article published on 11 February 2020

Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor-mediated enhancement of the MKP-IRF3 axis.

artículo científico publicado en 2013

COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence.

artículo científico publicado en 2007

CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity

artículo científico publicado en 2021

Control of IL-17 receptor signaling and tissue inflammation by the p38α-MKP-1 signaling axis in a mouse model of multiple sclerosis

artículo científico publicado en 2015

Control of T Cell Fates and Immune Tolerance by p38α Signaling in Mucosal CD103+ Dendritic Cells ⬇️

artículo científico publicado el 10 de junio de 2013

Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells.

artículo científico publicado en 2014

Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis

artículo científico publicado en 2006

Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis.

artículo científico publicado en 2017

Cutting edge: Discrete functions of mTOR signaling in invariant NKT cell development and NKT17 fate decision.

artículo científico publicado en 2014

Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis

artículo científico publicado en 2010

Cutting edge: regulation of T cell trafficking and primary immune responses by sphingosine 1-phosphate receptor 1.

artículo científico publicado en 2005

Deprivation of MKK7 in cardiomyocytes provokes heart failure in mice when exposed to pressure overload

artículo científico publicado en 2011

Dietary Fat Inflames CD4+ T Cell Memory in Obesity.

artículo científico publicado en 2017

Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.

artículo científico publicado en 2018

Epigenetic and transcriptional programs lead to default IFN-gamma production by gammadelta T cells

scientific article published on 01 March 2007

GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells.

artículo científico publicado en 2004

GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever.

artículo científico publicado en 2018

Genetic dissection of dendritic cell homeostasis and function: lessons from cell type-specific gene ablation

artículo científico

Gfi1-Foxo1 axis controls the fidelity of effector gene expression and developmental maturation of thymocytes

artículo científico publicado en 2016

Gfi1: a unique controller of T(reg) cells.

artículo científico publicado en 2013

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

artículo científico publicado en 2011

Hallmarks of T-cell Exit from Quiescence

artículo científico publicado en 2018

Helper T cell differentiation

scientific article published on 12 March 2019

Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells

artículo científico publicado en 2018

Homeostasis and transitional activation of regulatory T cells require c-Myc

scientific article published on 01 January 2020

Homeostatic control of metabolic and functional fitness of Treg cells by LKB1 signalling.

artículo científico publicado en 2017

I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection

artículo científico publicado en 2013

Inflammasome-derived IL-1β regulates the production of GM-CSF by CD4(+) T cells and γδ T cells

artículo científico publicado en 2012

Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells.

artículo científico publicado en 2013

Innate recognition of non-self nucleic acids.

artículo científico publicado en 2008

Integrative Proteomics and Phosphoproteomics Profiling Reveals Dynamic Signaling Networks and Bioenergetics Pathways Underlying T Cell Activation.

artículo científico publicado en 2017

Investigating Cellular Quiescence of T Lymphocytes and Antigen-Induced Exit from Quiescence.

artículo científico publicado en 2018

JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate.

artículo científico publicado en 2012

JNK1 is essential for CD8+ T cell-mediated tumor immune surveillance.

artículo científico publicado en 2005

LCK senses asparagine for T cell activation

artículo científico publicado en 2021

LKB1 orchestrates dendritic cell metabolic quiescence and anti-tumor immunity

artículo científico publicado en 2019

Lipid signalling enforces functional specialization of T<sub>reg</sub> cells in tumours

artículo científico publicado en 2021

Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination

artículo científico publicado en 2009

Loss of mitogen-activated protein kinase kinase kinase 4 (MEKK4) results in enhanced apoptosis and defective neural tube development.

artículo científico publicado en 2005

Mammalian Sterile 20-like Kinase 1 (Mst1) Enhances the Stability of Forkhead Box P3 (Foxp3) and the Function of Regulatory T Cells by Modulating Foxp3 Acetylation.

artículo científico publicado en 2015

Metabolic adaptation of lymphocytes in immunity and disease

artículo científico publicado en 2022

Metabolic control of T<sub>FH</sub> cells and humoral immunity by phosphatidylethanolamine

artículo científico publicado en 2021

Metabolic control of regulatory T cell development and function

artículo científico publicado en 2014

Metabolic coordination of T cell quiescence and activation

artículo científico publicado en 2019

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity.

artículo científico publicado en 2018

Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation

artículo científico publicado en 2016

Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells

artículo científico publicado en 2018

Metabolic sleuthing solves a rare immunodeficiency disease

artículo científico publicado en 2019

Metabolism and lymphocyte biology

artículo científico publicado en 2015

Metabolism in Immune Cell Differentiation and Function.

artículo científico publicado en 2017

Naturally activated V gamma 4 gamma delta T cells play a protective role in tumor immunity through expression of eomesodermin.

scientific article published on 04 June 2010

Novel specialized cell state and spatial compartments within the germinal center

artículo científico publicado en 2020

Nutrient and Metabolic Sensing in T Cell Responses

artículo científico publicado en 2017

PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development.

artículo científico publicado en 2017

Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection

artículo científico publicado en 2013

Regulation and function of mTOR signalling in T cell fate decisions ⬇️

artículo científico publicado el 20 de abril de 2012

Regulation of JNK and p38 MAPK in the immune system: signal integration, propagation and termination.

scientific article published on 08 September 2009

Regulation of TH17 cell differentiation by innate immune signals ⬇️

artículo científico publicado el 16 de abril de 2012

Sensing the enemy within

artículo científico publicado en 2007

Signaling by the phosphatase MKP-1 in dendritic cells imprints distinct effector and regulatory T cell fates

artículo científico publicado en 2011

Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity

artículo científico publicado en 2011

Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation

artículo científico publicado en 2012

Somatic mutation and germline variants of MINPP1, a phosphatase gene located in proximity to PTEN on 10q23.3, in follicular thyroid carcinomas.

artículo científico publicado en 2001

Sphingosine-1-phosphate and immune regulation: trafficking and beyond

artículo científico publicado en 2010

Sprouty branches out to control T cell memory.

artículo científico publicado en 2018

Studies on MAP Kinase signaling in the immune system.

artículo científico publicado en 2010

T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming

artículo científico publicado en 2013

TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation.

artículo científico publicado en 2018

Targeted deletion of Minpp1 provides new insight into the activity of multiple inositol polyphosphate phosphatase in vivo

artículo científico publicado en 2000

The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells

artículo científico publicado en 2015

The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells.

artículo científico publicado en 2010

The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.

artículo científico publicado en 2006

The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus.

artículo científico publicado en 2013

The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.

artículo científico publicado en 2009

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

artículo científico publicado en 2011

The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function

artículo científico publicado en 2011

Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function.

artículo científico publicado en 2012

Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses.

artículo científico publicado en 2015

Tristetraprolin Limits Inflammatory Cytokine Production in Tumor-Associated Macrophages in an mRNA Decay-Independent Manner.

artículo científico publicado en 2015

Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs

scientific journal article

Tuberous sclerosis 1 (Tsc1)-dependent metabolic checkpoint controls development of dendritic cells.

artículo científico publicado en 2013

Tuning mTOR activity for immune balance.

artículo científico publicado en 2013

c-Myc and AP4: a relay team for metabolic reprogramming of CD8+ T cells

artículo científico publicado en 2014

iNKT cells require TSC1 for terminal maturation and effector lineage fate decisions

artículo científico publicado en 2014

mTOR Links Environmental Signals to T Cell Fate Decisions.

artículo científico publicado en 2014

mTOR and lymphocyte metabolism ⬇️

artículo científico publicado el 28 de mayo de 2013

mTOR and metabolic pathways in T cell quiescence and functional activation ⬇️

artículo científico publicado el 1 de febrero de 2013

mTOR and metabolic regulation of conventional and regulatory T cells.

artículo científico publicado en 2015

mTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis.

artículo científico publicado en 2018

mTOR signaling and transcriptional regulation in T lymphocytes

artículo científico

mTOR signaling at the crossroads of environmental signals and T-cell fate decisions

artículo científico publicado en 2020

mTOR signaling in the differentiation and function of regulatory and effector T cells.

artículo científico publicado en 2017

mTOR signaling, Tregs and immune modulation

artículo científico publicado en 2014

mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation.

artículo científico publicado en 2016

mTORC1 couples immune signals and metabolic programming to establish T(reg)-cell function

artículo científico publicado en 2013

Lista de obras de Hongbo Chi

AMPK helps T cells survive nutrient starvation

Acetylation of MKP-1 and the control of inflammation.

Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

Autophagy modulates CD4+ T-cell lineage recommitment upon pathogen infection

Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor-mediated enhancement of the MKP-IRF3 axis.

COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence.

CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity

Control of IL-17 receptor signaling and tissue inflammation by the p38α-MKP-1 signaling axis in a mouse model of multiple sclerosis

Control of T Cell Fates and Immune Tolerance by p38α Signaling in Mucosal CD103+ Dendritic Cells ⬇️

Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells.

Critical function of Bmx/Etk in ischemia-mediated arteriogenesis and angiogenesis

Critical roles of mTORC1 signaling and metabolic reprogramming for M-CSF-mediated myelopoiesis.

Cutting edge: Discrete functions of mTOR signaling in invariant NKT cell development and NKT17 fate decision.

Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis

Cutting edge: regulation of T cell trafficking and primary immune responses by sphingosine 1-phosphate receptor 1.

Deprivation of MKK7 in cardiomyocytes provokes heart failure in mice when exposed to pressure overload

Dietary Fat Inflames CD4+ T Cell Memory in Obesity.

Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.

Epigenetic and transcriptional programs lead to default IFN-gamma production by gammadelta T cells

GADD45beta/GADD45gamma and MEKK4 comprise a genetic pathway mediating STAT4-independent IFNgamma production in T cells.

GSDMD is critical for autoinflammatory pathology in a mouse model of Familial Mediterranean Fever.

Genetic dissection of dendritic cell homeostasis and function: lessons from cell type-specific gene ablation

Gfi1-Foxo1 axis controls the fidelity of effector gene expression and developmental maturation of thymocytes

Gfi1: a unique controller of T(reg) cells.

HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells

Hallmarks of T-cell Exit from Quiescence

Helper T cell differentiation

Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells

Homeostasis and transitional activation of regulatory T cells require c-Myc

Homeostatic control of metabolic and functional fitness of Treg cells by LKB1 signalling.

I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection

Inflammasome-derived IL-1β regulates the production of GM-CSF by CD4(+) T cells and γδ T cells

Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells.

Innate recognition of non-self nucleic acids.

Integrative Proteomics and Phosphoproteomics Profiling Reveals Dynamic Signaling Networks and Bioenergetics Pathways Underlying T Cell Activation.

Investigating Cellular Quiescence of T Lymphocytes and Antigen-Induced Exit from Quiescence.

JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate.

JNK1 is essential for CD8+ T cell-mediated tumor immune surveillance.

LCK senses asparagine for T cell activation

LKB1 orchestrates dendritic cell metabolic quiescence and anti-tumor immunity

Lipid signalling enforces functional specialization of T<sub>reg</sub> cells in tumours

Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination

Loss of mitogen-activated protein kinase kinase kinase 4 (MEKK4) results in enhanced apoptosis and defective neural tube development.

Mammalian Sterile 20-like Kinase 1 (Mst1) Enhances the Stability of Forkhead Box P3 (Foxp3) and the Function of Regulatory T Cells by Modulating Foxp3 Acetylation.

Metabolic adaptation of lymphocytes in immunity and disease

Metabolic control of T<sub>FH</sub> cells and humoral immunity by phosphatidylethanolamine

Metabolic control of regulatory T cell development and function

Metabolic coordination of T cell quiescence and activation

Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity.

Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation

Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells

Metabolic sleuthing solves a rare immunodeficiency disease

Metabolism and lymphocyte biology

Metabolism in Immune Cell Differentiation and Function.

Naturally activated V gamma 4 gamma delta T cells play a protective role in tumor immunity through expression of eomesodermin.

Novel specialized cell state and spatial compartments within the germinal center

Nutrient and Metabolic Sensing in T Cell Responses

PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development.

Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection

Regulation and function of mTOR signalling in T cell fate decisions ⬇️

Regulation of JNK and p38 MAPK in the immune system: signal integration, propagation and termination.

Regulation of TH17 cell differentiation by innate immune signals ⬇️

Sensing the enemy within

Signaling by the phosphatase MKP-1 in dendritic cells imprints distinct effector and regulatory T cell fates

Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity

Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation

Somatic mutation and germline variants of MINPP1, a phosphatase gene located in proximity to PTEN on 10q23.3, in follicular thyroid carcinomas.

Sphingosine-1-phosphate and immune regulation: trafficking and beyond

Sprouty branches out to control T cell memory.

Studies on MAP Kinase signaling in the immune system.

T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming

TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation.

Targeted deletion of Minpp1 provides new insight into the activity of multiple inositol polyphosphate phosphatase in vivo

The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells

The S1P(1)-mTOR axis directs the reciprocal differentiation of T(H)1 and T(reg) cells.

The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.

The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus.

The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation