Lista de obras - F Hernandez - Dominio Público Uruguay

A Simple Model to Study Tau Pathology.

artículo científico publicado en 2016

Absence of CX3CR1 impairs the internalization of Tau by microglia.

artículo científico

Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery attributable to aggregate formation.

artículo científico publicado en 2010

Alpha-helix structure in Alzheimer's disease aggregates of tau-protein.

artículo científico publicado en 2002

Alternative neural circuitry that might be impaired in the development of Alzheimer disease

artículo científico publicado en 2015

Alzheimer disease-like cellular phenotype of newborn granule neurons can be reversed in GSK-3β-overexpressing mice.

artículo científico publicado en 2013

Argyrophilic grain pathology as a natural model of tau propagation.

artículo científico publicado en 2014

Assembly in vitro of tau protein and its implications in Alzheimer's disease.

artículo científico publicado en 2004

Binding of tau protein to the ends of ex vivo paired helical filaments.

artículo científico publicado en 2008

Biochemical, ultrastructural, and reversibility studies on huntingtin filaments isolated from mouse and human brain.

artículo científico publicado en 2004

Boronate-tau mediated uptake in neurons.

artículo científico publicado en 2014

Calpain regulates N-terminal interaction of GSK-3β with 14-3-3ζ, p53 and PKB but not with axin ⬇️

artículo científico publicado el 13 de junio de 2011

Calpain-mediated truncation of GSK-3 in post-mortem brain samples.

artículo científico publicado en 2009

Centro de Biologia Molecular "Severo Ochoa": a center for basic research into Alzheimer's disease.

artículo científico publicado en 2010

Changes in tau phosphorylation in hibernating rodents.

artículo científico publicado en 2013

Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert.

artículo científico publicado en 2006

Chronic lithium treatment decreases mutant tau protein aggregation in a transgenic mouse model.

artículo científico publicado en 2003

Coenzyme Q Induces Tau Aggregation, Tau Filaments, and Hirano Bodies

artículo científico publicado en 2008

Cognitive Decline in Neuronal Aging and Alzheimer's Disease: Role of NMDA Receptors and Associated Proteins.

artículo científico publicado en 2017

Commentary: Genome-wide association study identifies 74 loci associated with educational attainment.

artículo científico publicado en 2017

Decreased adult neurogenesis in hibernating Syrian hamster

artículo científico publicado en 2016

Decreased glycogen synthase kinase-3 levels and activity contribute to Huntington's disease.

artículo científico publicado en 2015

Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

artículo científico publicado en 2001

Differences Between Human and Murine Tau at the N-terminal End

artículo científico publicado en 2020

Differences in structure and function between human and murine tau

artículo científico publicado en 2018

Different susceptibility to neurodegeneration of dorsal and ventral hippocampal dentate gyrus: a study with transgenic mice overexpressing GSK3β.

artículo científico publicado en 2011

Direct Evidence of Internalization of Tau by Microglia In Vitro and In Vivo.

artículo científico publicado en 2015

Dissociation between secretion and protein phosphorylation in agonist-stimulated platelets; action of PCA-4230, a new antithrombotic drug

scientific article published on 01 July 1994

Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo

artículo científico publicado en 2006

Endothelin inhibits histamine-induced cyclic AMP accumulation in bovine brain vessels

artículo científico publicado en 2000

Endothelin stimulates protein phosphorylation in blood-brain barrier.

artículo científico publicado en 1996

Endothelin-1 increases isoprenaline-enhanced cyclic AMP levels in cerebral cortex

artículo científico publicado en 2000

Endothelin-1 stimulates myristoylated alanine-rich C-kinase substrate (MARCKS) phosphorylation in rat cerebellar slices

scientific article published on 01 July 1995

Enhanced induction of the immunoproteasome by interferon gamma in neurons expressing mutant Huntingtin.

artículo científico publicado en 2004

Excitotoxic inactivation of constitutive oxidative stress detoxification pathway in neurons can be rescued by PKD1.

artículo científico publicado en 2017

Excitotoxicity induced by kainic acid provokes glycogen synthase kinase-3 truncation in the hippocampus

artículo científico publicado en 2015

Expression of frontotemporal dementia with parkinsonism associated to chromosome 17 tau induces specific degeneration of the ventral dentate gyrus and depressive-like behavior in mice.

artículo científico publicado en 2011

Extracellular Monomeric Tau Is Internalized by Astrocytes

artículo científico publicado en 2019

Extracellular tau is toxic to neuronal cells.

artículo científico publicado en 2006

FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and Tau filaments in forebrain

artículo científico publicado en 2001

Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3.

artículo científico publicado en 2006

Function of tau protein in adult newborn neurons

scientific journal article

Further studies on the mechanism of action of substance P in rat brain, involving selective phosphatidylinositol hydrolysis

scientific article published on 01 October 1995

GSK-3 inhibitors for Alzheimer's disease.

artículo científico publicado en 2007

GSK-3β overexpression causes reversible alterations on postsynaptic densities and dendritic morphology of hippocampal granule neurons in vivo.

artículo científico publicado en 2013

GSK-3β, a pivotal kinase in Alzheimer disease.

artículo científico publicado en 2014

GSK3 and tau: two convergence points in Alzheimer's disease.

artículo científico

GSK3 inhibitors and disease.

artículo científico publicado en 2009

GSK3: a possible link between beta amyloid peptide and tau protein.

artículo científico publicado en 2009

GSK3β Overexpression in Dentate Gyrus Neural Precursor Cells Expands the Progenitor Pool and Enhances Memory Skills.

artículo científico publicado en 2016

GSK3β overexpression driven by GFAP promoter improves rotarod performance

artículo científico publicado en 2019

GSK3β overexpression induces neuronal death and a depletion of the neurogenic niches in the dentate gyrus.

artículo científico publicado en 2010

Glycogen synthase kinase-3 inhibition is integral to long-term potentiation

artículo científico publicado en 2007

Glycogen synthase kinase-3β regulates fractalkine production by altering its trafficking from Golgi to plasma membrane: implications for Alzheimer's disease

artículo científico publicado en 2016

Hippocampal neuronal subpopulations are differentially affected in double transgenic mice overexpressing frontotemporal dementia and parkinsonism linked to chromosome 17 tau and glycogen synthase kinase-3beta.

artículo científico publicado en 2008

Huntington's disease is a four-repeat tauopathy with tau nuclear rods.

artículo científico publicado en 2014

Identification of nitric oxide synthases in isolated bovine brain vessels

artículo científico publicado en 1996

In vitro tau fibrillization: mapping protein regions.

artículo científico publicado en 2006

Induction of paclitaxel resistance by the Kaposi's sarcoma-associated herpesvirus latent protein LANA2.

artículo científico publicado en 2007

Intra- and extracellular protein interactions with tau.

artículo científico publicado en 2010

Intracellular and extracellular microtubule associated protein tau as a therapeutic target in Alzheimer disease and other tauopathies.

artículo científico publicado en 2015

Involvement of calcium in phosphoinositide metabolism in the blood-brain barrier

scientific article published on 01 March 1995

Lithium as a Treatment for Alzheimer's Disease: The Systems Pharmacology Perspective

scientific article published on 01 January 2019

Looking at the periphery—new hypothesis to look for new targets for Alzheimer’s disease therapy

artículo científico publicado en 2023

Looking for novel functions of tau.

artículo científico

M1 muscarinic receptor activation protects neurons from beta-amyloid toxicity. A role for Wnt signaling pathway

artículo científico publicado en 2004

MicroRNA-22 Controls Aberrant Neurogenesis and Changes in Neuronal Morphology After Status Epilepticus

article

Microtubule depolymerization and tau phosphorylation.

artículo científico publicado en 2013

Natriuretic peptide-induced cyclic GMP accumulation in adult guinea-pig cerebellar slices.

artículo científico publicado en 1994

Neuronal apoptosis and reversible motor deficit in dominant-negative GSK-3 conditional transgenic mice.

artículo científico publicado en 2007

Neuronal models for studying tau pathology.

artículo científico publicado en 2010

New Beginnings in Alzheimer's Disease: The Most Prevalent Tauopathy.

artículo científico publicado en 2018

New Features about Tau Function and Dysfunction

artículo científico publicado en 2016

Novel connection between newborn granule neurons and the hippocampal CA2 field

artículo científico publicado en 2014

Novel function of Tau in regulating the effects of external stimuli on adult hippocampal neurogenesis

artículo científico publicado en 2016

Peripheral nervous system effects in the PS19 tau transgenic mouse model of tauopathy

artículo científico publicado en 2019

Peripherally triggered and GSK-3β-driven brain inflammation differentially skew adult hippocampal neurogenesis, behavioral pattern separation and microglial activation in response to ibuprofen.

artículo científico publicado en 2014

Pertussis toxin-insensitive regulation of phosphatidylinositol hydrolysis by vanadate in brain microvessels

artículo científico publicado el 1 de diciembre de 1991

Phospho-Tau Accumulation and Structural Alterations of the Golgi Apparatus of Cortical Pyramidal Neurons in the P301S Tauopathy Mouse Model

artículo científico publicado en 2017

Phospho-Tau Changes in the Human CA1 During Alzheimer's Disease Progression

artículo científico publicado en 2019

Phosphorylation modulates the alpha-helical structure and polymerization of a peptide from the third tau microtubule-binding repeat.

artículo científico publicado en 2004

Profiling of Argonaute-2-loaded microRNAs in a mouse model of frontotemporal dementia with parkinsonism-17

artículo científico publicado en 2018

Propagation of Tau via Extracellular Vesicles

artículo científico publicado en 2019

Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease.

artículo científico publicado en 2001

Protein phosphorylation in the blood-brain barrier. Possible presence of MARCKS in brain microvessels

artículo científico publicado en 1996

Proteins and microRNAs are differentially expressed in tear fluid from patients with Alzheimer's disease

scientific article published on 28 October 2019

Role of calcium on protein phosphorylation in collagen-stimulated platelets. Effect of a new dihydropyridine derivative

scientific article published on 01 October 1989

Role of glycogen synthase kinase-3 in Alzheimer's disease pathogenesis and glycogen synthase kinase-3 inhibitors.

artículo científico publicado en 2010

Role of neuroinflammation in adult neurogenesis and Alzheimer disease: therapeutic approaches

artículo científico publicado en 2013

Role of polyglycine repeats in the regulation of glycogen synthase kinase activity.

artículo científico publicado en 2008

Role of tau protein in both physiological and pathological conditions.

artículo científico publicado en 2004

Secretion of full-length tau or tau fragments in a cell culture model.

artículo científico publicado en 2016

Selective alterations of neurons and circuits related to early memory loss in Alzheimer's disease.

artículo científico publicado en 2014

Sources of extracellular tau and its signaling.

artículo científico

TNAP Plays a Key Role in Neural Differentiation as well as in Neurodegenerative Disorders.

artículo científico

Tau Overexpression Results in Its Secretion via Membrane Vesicles

scientific article published on 21 January 2012

Tau Protein and Adult Hippocampal Neurogenesis ⬇️

artículo científico publicado el 9 de julio de 2012

Tau Spreading Mechanisms; Implications for Dysfunctional Tauopathies.

artículo científico publicado en 2018

Tau Structures

artículo científico publicado en 2016

Tau aggregates and tau pathology.

artículo científico publicado en 2008

Tau as a molecular marker of development, aging and neurodegenerative disorders.

artículo científico publicado en 2008

Tau isoform with three microtubule binding domains is a marker of new axons generated from the subgranular zone in the hippocampal dentate gyrus: implications for Alzheimer's disease.

artículo científico publicado en 2012

Tau phosphorylation in hippocampus results in toxic gain-of-function.

scientific article published on August 2010

Tau triggers tear secretion by interacting with muscarinic acetylcholine receptors in New Zealand white rabbits

artículo científico publicado en 2014

Tau-positive nuclear indentations in P301S tauopathy mice.

artículo científico publicado en 2016

Testing the ubiquitin-proteasome hypothesis of neurodegeneration in vivo.

artículo científico publicado en 2004

Tetrahydroaminoacridine affects the cholinergic function of blood-brain barrier.

artículo científico publicado en 1993

The involvement of cholinergic neurons in the spreading of tau pathology.

artículo científico publicado en 2013

The role of GSK3 in Alzheimer disease.

scientific article published on 27 May 2009

The role of glycogen synthase kinase 3 in the early stages of Alzheimers' disease.

artículo científico publicado en 2008

The ubiquitin-proteasome system in Huntington's disease.

artículo científico publicado en 2005

Thermodynamics of the interaction between Alzheimer's disease related tau protein and DNA

artículo científico publicado en 2014

Tramiprosate, a drug of potential interest for the treatment of Alzheimer's disease, promotes an abnormal aggregation of tau.

artículo científico publicado en 2007

Transgenic mouse models with tau pathology to test therapeutic agents for Alzheimer's disease.

artículo científico publicado en 2002

Validation of Suspected Somatic Single Nucleotide Variations in the Brain of Alzheimer's Disease Patients.

artículo científico publicado en 2017

p38 activation occurs mainly in microglia in the P301S Tauopathy mouse model

scientific article published on 08 February 2022

Lista de obras de F Hernandez

A Simple Model to Study Tau Pathology.

Absence of CX3CR1 impairs the internalization of Tau by microglia.

Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery attributable to aggregate formation.

Alpha-helix structure in Alzheimer's disease aggregates of tau-protein.

Alternative neural circuitry that might be impaired in the development of Alzheimer disease

Alzheimer disease-like cellular phenotype of newborn granule neurons can be reversed in GSK-3β-overexpressing mice.

Argyrophilic grain pathology as a natural model of tau propagation.

Assembly in vitro of tau protein and its implications in Alzheimer's disease.

Binding of tau protein to the ends of ex vivo paired helical filaments.

Biochemical, ultrastructural, and reversibility studies on huntingtin filaments isolated from mouse and human brain.

Boronate-tau mediated uptake in neurons.

Calpain regulates N-terminal interaction of GSK-3β with 14-3-3ζ, p53 and PKB but not with axin ⬇️

Calpain-mediated truncation of GSK-3 in post-mortem brain samples.

Centro de Biologia Molecular "Severo Ochoa": a center for basic research into Alzheimer's disease.

Changes in tau phosphorylation in hibernating rodents.

Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert.

Chronic lithium treatment decreases mutant tau protein aggregation in a transgenic mouse model.

Coenzyme Q Induces Tau Aggregation, Tau Filaments, and Hirano Bodies

Cognitive Decline in Neuronal Aging and Alzheimer's Disease: Role of NMDA Receptors and Associated Proteins.

Commentary: Genome-wide association study identifies 74 loci associated with educational attainment.

Decreased adult neurogenesis in hibernating Syrian hamster

Decreased glycogen synthase kinase-3 levels and activity contribute to Huntington's disease.

Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

Differences Between Human and Murine Tau at the N-terminal End

Differences in structure and function between human and murine tau

Different susceptibility to neurodegeneration of dorsal and ventral hippocampal dentate gyrus: a study with transgenic mice overexpressing GSK3β.

Direct Evidence of Internalization of Tau by Microglia In Vitro and In Vivo.

Dissociation between secretion and protein phosphorylation in agonist-stimulated platelets; action of PCA-4230, a new antithrombotic drug

Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo

Endothelin inhibits histamine-induced cyclic AMP accumulation in bovine brain vessels

Endothelin stimulates protein phosphorylation in blood-brain barrier.

Endothelin-1 increases isoprenaline-enhanced cyclic AMP levels in cerebral cortex

Endothelin-1 stimulates myristoylated alanine-rich C-kinase substrate (MARCKS) phosphorylation in rat cerebellar slices

Enhanced induction of the immunoproteasome by interferon gamma in neurons expressing mutant Huntingtin.

Excitotoxic inactivation of constitutive oxidative stress detoxification pathway in neurons can be rescued by PKD1.

Excitotoxicity induced by kainic acid provokes glycogen synthase kinase-3 truncation in the hippocampus

Expression of frontotemporal dementia with parkinsonism associated to chromosome 17 tau induces specific degeneration of the ventral dentate gyrus and depressive-like behavior in mice.

Extracellular Monomeric Tau Is Internalized by Astrocytes

Extracellular tau is toxic to neuronal cells.

FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and Tau filaments in forebrain

Full reversal of Alzheimer's disease-like phenotype in a mouse model with conditional overexpression of glycogen synthase kinase-3.

Function of tau protein in adult newborn neurons

Further studies on the mechanism of action of substance P in rat brain, involving selective phosphatidylinositol hydrolysis

GSK-3 inhibitors for Alzheimer's disease.

GSK-3β overexpression causes reversible alterations on postsynaptic densities and dendritic morphology of hippocampal granule neurons in vivo.

GSK-3β, a pivotal kinase in Alzheimer disease.

GSK3 and tau: two convergence points in Alzheimer's disease.

GSK3 inhibitors and disease.

GSK3: a possible link between beta amyloid peptide and tau protein.

GSK3β Overexpression in Dentate Gyrus Neural Precursor Cells Expands the Progenitor Pool and Enhances Memory Skills.

GSK3β overexpression driven by GFAP promoter improves rotarod performance

GSK3β overexpression induces neuronal death and a depletion of the neurogenic niches in the dentate gyrus.

Glycogen synthase kinase-3 inhibition is integral to long-term potentiation

Glycogen synthase kinase-3β regulates fractalkine production by altering its trafficking from Golgi to plasma membrane: implications for Alzheimer's disease

Hippocampal neuronal subpopulations are differentially affected in double transgenic mice overexpressing frontotemporal dementia and parkinsonism linked to chromosome 17 tau and glycogen synthase kinase-3beta.

Huntington's disease is a four-repeat tauopathy with tau nuclear rods.

Identification of nitric oxide synthases in isolated bovine brain vessels

In vitro tau fibrillization: mapping protein regions.

Induction of paclitaxel resistance by the Kaposi's sarcoma-associated herpesvirus latent protein LANA2.

Intra- and extracellular protein interactions with tau.

Intracellular and extracellular microtubule associated protein tau as a therapeutic target in Alzheimer disease and other tauopathies.

Involvement of calcium in phosphoinositide metabolism in the blood-brain barrier

Lithium as a Treatment for Alzheimer's Disease: The Systems Pharmacology Perspective

Looking at the periphery—new hypothesis to look for new targets for Alzheimer’s disease therapy

Looking for novel functions of tau.

M1 muscarinic receptor activation protects neurons from beta-amyloid toxicity. A role for Wnt signaling pathway

MicroRNA-22 Controls Aberrant Neurogenesis and Changes in Neuronal Morphology After Status Epilepticus

Microtubule depolymerization and tau phosphorylation.

Natriuretic peptide-induced cyclic GMP accumulation in adult guinea-pig cerebellar slices.

Neuronal apoptosis and reversible motor deficit in dominant-negative GSK-3 conditional transgenic mice.

Neuronal models for studying tau pathology.

New Beginnings in Alzheimer's Disease: The Most Prevalent Tauopathy.

New Features about Tau Function and Dysfunction

Novel connection between newborn granule neurons and the hippocampal CA2 field

Novel function of Tau in regulating the effects of external stimuli on adult hippocampal neurogenesis

Peripheral nervous system effects in the PS19 tau transgenic mouse model of tauopathy

Peripherally triggered and GSK-3β-driven brain inflammation differentially skew adult hippocampal neurogenesis, behavioral pattern separation and microglial activation in response to ibuprofen.

Pertussis toxin-insensitive regulation of phosphatidylinositol hydrolysis by vanadate in brain microvessels

Phospho-Tau Accumulation and Structural Alterations of the Golgi Apparatus of Cortical Pyramidal Neurons in the P301S Tauopathy Mouse Model