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Lista de obras de George Muscat

A dynamic role for HDAC7 in MEF2-mediated muscle differentiation.

artículo científico publicado en 2001

Beta-adrenergic signaling regulates NR4A nuclear receptor and metabolic gene expression in multiple tissues.

artículo científico publicado en 2009

Breast cancer prognosis predicted by nuclear receptor-coregulator networks.

artículo científico publicado en 2014

CARM1/PRMT4 is necessary for the glycogen gene expression programme in skeletal muscle cells.

artículo científico publicado en 2012

Characterization of the AB (AF-1) region in the muscle-specific retinoid X receptor-gamma: evidence that the AF-1 region functions in a cell-specific manner

artículo científico publicado en 1996

Chicken ovalbumin upstream promoter-transcription factor II regulates nuclear receptor, myogenic, and metabolic gene expression in skeletal muscle cells.

artículo científico publicado en 2010

Class I histone deacetylases sequentially interact with MyoD and pRb during skeletal myogenesis.

artículo científico publicado en 2001

Disruption of Rorα1 and cholesterol 25-hydroxylase expression attenuates phagocytosis in male Rorαsg/sg mice.

artículo científico publicado en 2012

Distinct nuclear receptor expression in stroma adjacent to breast tumors.

artículo científico publicado en 2013

Domains of Brn-2 that mediate homodimerization and interaction with general and melanocytic transcription factors

artículo científico publicado en 2000

Effect of disrupted SOX18 transcription factor function on tumor growth, vascularization, and endothelial development

artículo científico publicado en 2006

Expression profiling of skeletal muscle following acute and chronic beta2-adrenergic stimulation: implications for hypertrophy, metabolism and circadian rhythm.

artículo científico publicado en 2009

Expression vectors encoding human growth hormone (hGH) controlled by human muscle-specific promoters: prospects for regulated production of hGH delivered by myoblast transfer or intravenous injection

scientific article published on 01 August 1994

Halofenate is a selective peroxisome proliferator-activated receptor gamma modulator with antidiabetic activity.

artículo científico

Homozygous staggerer (sg/sg) mice display improved insulin sensitivity and enhanced glucose uptake in skeletal muscle

artículo científico publicado el 29 de enero de 2011

Identification and validation of the pathways and functions regulated by the orphan nuclear receptor, ROR alpha1, in skeletal muscle.

artículo científico publicado en 2010

Identification of deoxyribonucleic acid sequences that bind retinoid-X receptor-gamma with high affinity.

artículo científico

International Union of Pharmacology. LXVI. Orphan nuclear receptors

artículo científico publicado en 2006

Mice null for sox18 are viable and display a mild coat defect

artículo científico publicado en 2000

Minireview: Nuclear hormone receptor 4A signaling: implications for metabolic disease.

artículo científico publicado en 2010

Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice

scientific journal article

NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF.

artículo científico publicado en 2017

Not a minute to waste

artículo científico publicado en 2000

Nuclear Receptor Profiling of Ovarian Granulosa Cell Tumors

article

Nuclear receptor expression in human differentiated thyroid tumors

artículo científico publicado en 2014

Nuclear receptors and epigenetic signaling: Novel regulators of glycogen metabolism in skeletal muscle

artículo científico publicado el 11 de julio de 2013

Nucleotide sequence and expression of the human skeletal alpha-actin gene: evolution of functional regulatory domains

artículo científico publicado en 1988

Nur77 regulates lipolysis in skeletal muscle cells. Evidence for cross-talk between the beta-adrenergic and an orphan nuclear hormone receptor pathway.

artículo científico publicado en 2005

Orphan Nuclear Receptors and the Regulation of Nutrient Metabolism: Understanding Obesity

artículo científico publicado el 1 de junio de 2012

Orphan nuclear receptors: therapeutic opportunities in skeletal muscle.

artículo científico publicado en 2006

PPARgamma agonists attenuate proliferation and modulate Wnt/beta-catenin signalling in melanoma cells.

artículo científico publicado en 2008

PRMT2 and RORγ expression are associated with breast cancer survival outcomes

artículo científico publicado en 2014

Proliferin, a Prolactin/Growth Hormone-Like Peptide Represses Myogenic-Specific Transcription by the Suppression of an Essential Serum Response Factor-Like DNA-Binding Activity

artículo científico publicado el 1 de junio de 1991

RORalpha regulates the expression of genes involved in lipid homeostasis in skeletal muscle cells: caveolin-3 and CPT-1 are direct targets of ROR

scientific journal article

RORα and 25-Hydroxycholesterol Crosstalk Regulates Lipid Droplet Homeostasis in Macrophages

artículo científico publicado en 2016

Regulation of NR4A nuclear receptor expression by oncogenic BRAF in melanoma cells.

artículo científico publicado en 2011

Regulation of cholesterol homeostasis and lipid metabolism in skeletal muscle by liver X receptors.

artículo científico publicado en 2002

Regulation of vertebrate muscle differentiation by thyroid hormone: the role of the myoD gene family.

artículo científico publicado en 1995

Repression of basal transcription by vitamin D receptor: evidence for interaction of unliganded vitamin D receptor with two receptor interaction domains in RIP13delta1.

artículo científico publicado en 1998

Research resource: nuclear receptors as transcriptome: discriminant and prognostic value in breast cancer

artículo científico publicado en 2013

Retinoid-related orphan receptor alpha and the regulation of lipid homeostasis.

artículo científico publicado en 2011

Rev-erbbeta regulates the expression of genes involved in lipid absorption in skeletal muscle cells: evidence for cross-talk between orphan nuclear receptors and myokines

scientific journal article

Role of HuR in skeletal myogenesis through coordinate regulation of muscle differentiation genes

artículo científico publicado en 2003

SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse

scientific journal article

Sequence and expression of Sox-18 encoding a new HMG-box transcription factor.

artículo científico publicado en 1995

Ski overexpression in skeletal muscle modulates genetic programs that control susceptibility to diet-induced obesity and insulin signaling

artículo científico publicado en 2012

Sox18 mutations in theragged mouse allelesragged-like andopossum

article

Structure-function analysis of the Rev-erbA and RVR ligand-binding domains reveals a large hydrophobic surface that mediates corepressor binding and a ligand cavity occupied by side chains

scientific article published on 01 May 2000

Structure/function analysis of a dUTPase: catalytic mechanism of a potential chemotherapeutic target

scientific article published on 01 April 1999

TRAP220 is modulated by the antineoplastic agent 6-Mercaptopurine, and mediates the activation of the NR4A subgroup of nuclear receptors.

artículo científico publicado en 2005

The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite 6-mercaptopurine

scientific journal article

The Chicken Ovalbumin Upstream Promoter-Transcription Factors Modulate Genes and Pathways Involved in Skeletal Muscle Cell Metabolism

artículo científico publicado en 2006

The NR4A2 nuclear receptor is recruited to novel nuclear foci in response to UV irradiation and participates in nucleotide excision repair

artículo científico publicado en 2013

The Nuclear Receptor, Nor-1, Induces the Physiological Responses Associated With Exercise

artículo científico publicado en 2016

The Nuclear Receptor, RORγ, Regulates Pathways Necessary for Breast Cancer Metastasis

artículo científico publicado en 2016

The Ski proto-oncogene regulates body composition and suppresses lipogenesis.

artículo científico publicado en 2009

The VCAM-1 gene that encodes the vascular cell adhesion molecule is a target of the Sry-related high mobility group box gene, Sox18

scientific journal article

The corepressor N-CoR and its variants RIP13a and RIP13Delta1 directly interact with the basal transcription factors TFIIB, TAFII32 and TAFII70.

artículo científico publicado en 1998

The effects of lectin transformation on cytoplasmic polyadenylated RNA from human lymphocytes

artículo científico publicado en 1983

The orphan nuclear receptor, NOR-1, a target of beta-adrenergic signaling, regulates gene expression that controls oxidative metabolism in skeletal muscle

scientific journal article

The orphan nuclear receptor, RORalpha, regulates gene expression that controls lipid metabolism: staggerer (SG/SG) mice are resistant to diet-induced obesity.

artículo científico publicado en 2008

The retinoic acid and retinoid X receptors are differentially expressed during myoblast differentiation.

artículo científico publicado en 1994

TheSry-Related GeneSox18Maps to Distal Mouse Chromosome 2

article

Therapeutic Implications of Epigenetic Signaling in Breast Cancer.

artículo científico publicado en 2016

Trans-activation and DNA-binding properties of the transcription factor, Sox-18

scientific journal article

Transcriptional repression by COUP-TF II is dependent on the C-terminal domain and involves the N-CoR variant, RIP13delta1.

artículo científico publicado en 1997

Transgenic Adipose-specific Expression of the Nuclear Receptor RORα Drives a Striking Shift in Fat Distribution and Impairs Glycemic Control.

artículo científico publicado en 2016

Transgenic muscle-specific Nor-1 expression regulates multiple pathways that effect adiposity, metabolism, and endurance

artículo científico publicado en 2013

Two receptor interaction domains in the corepressor, N-CoR/RIP13, are required for an efficient interaction with Rev-erbA alpha and RVR: physical association is dependent on the E region of the orphan receptors

artículo científico publicado en 1996