Lista de obras - Jean-Paul Renaud - Dominio Público Uruguay

3,5-T2 is an alternative ligand for the thyroid hormone receptor β1.

artículo científico publicado en 2013

A canonical structure for the ligand-binding domain of nuclear receptors

artículo científico publicado en 1996

A canonical structure for the ligand-binding domain of nuclear receptors

scientific article published on 01 February 1996

All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta

artículo científico publicado en 2003

Amphioxus postembryonic development reveals the homology of chordate metamorphosis.

artículo científico publicado en 2008

Binding of ligands and activation of transcription by nuclear receptors.

artículo científico publicado en 2001

Biophysics in drug discovery: impact, challenges and opportunities.

artículo científico publicado en 2016

Characterization of novel checkpoint kinase 1 inhibitors by in vitro assays and in human cancer cells treated with topoisomerase inhibitors.

artículo científico publicado en 2011

Cisplatin- and UV-damaged DNA lure the basal transcription factor TFIID/TBP.

artículo científico publicado en 1997

Conformational heterogeneity of cytochrome P450 3A4 revealed by high pressure spectroscopy.

artículo científico publicado en 2003

Cryo-EM in drug discovery: achievements, limitations and prospects

article

Effect of the distal residues on the vibrational modes of the Fe-CO bond in hemoglobin studied by protein engineering

scientific article published on 01 June 1990

Fragment-Based Drug Design: Computational and Experimental State of the Art ⬇️

artículo científico publicado el 1 de julio de 2011

High affinity of ergopeptides for cytochromes P450 3A. Importance of their peptide moiety for P450 recognition and hydroxylation of bromocriptine

artículo científico publicado en 1994

In silico fragment-based drug discovery: setup and validation of a fragment-to-lead computational protocol using S4MPLE.

artículo científico publicado en 2013

International Union of Pharmacology. LXVI. Orphan nuclear receptors

artículo científico publicado en 2006

One Question, Multiple Answers: Biochemical and Biophysical Screening Methods Retrieve Deviating Fragment Hit Lists

artículo científico publicado en 2015

Particular ability of liver P450s3A to catalyze the oxidation of N omega-hydroxyarginine to citrulline and nitrogen oxides and occurrence in no synthases of a sequence very similar to the heme-binding sequence in P450s

scientific article published on 01 April 1993

Purification of the human RARgamma ligand-binding domain and crystallization of its complex with all-trans retinoic acid.

artículo científico

Recombinant yeast in drug metabolism.

artículo científico publicado en 1993

Retinoic acid receptor: a simulation analysis of retinoic acid binding and the resulting conformational changes

artículo científico publicado en 1999

Stereochemistry of carbon monoxide binding to normal human adult and Cowtown haemoglobins

artículo científico publicado en 1990

Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni

artículo científico publicado en 2013

Structural studies on nuclear receptors.

artículo científico publicado en 2000

Structure-function analysis of the Rev-erbA and RVR ligand-binding domains reveals a large hydrophobic surface that mediates corepressor binding and a ligand cavity occupied by side chains

scientific article published on 01 May 2000

Structure-function analysis reveals the molecular determinants of the impaired biological function of DAX-1 mutants in AHC patients

artículo científico publicado en 2003

Thermodynamic studies of substrate binding and spin transitions in human cytochrome P-450 3A4 expressed in yeast microsomes.

artículo científico publicado en 1996

X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.

artículo científico publicado en 2001

Lista de obras de Jean-Paul Renaud

3,5-T2 is an alternative ligand for the thyroid hormone receptor β1.

A canonical structure for the ligand-binding domain of nuclear receptors

A canonical structure for the ligand-binding domain of nuclear receptors

All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta

Amphioxus postembryonic development reveals the homology of chordate metamorphosis.

Binding of ligands and activation of transcription by nuclear receptors.

Biophysics in drug discovery: impact, challenges and opportunities.

Characterization of novel checkpoint kinase 1 inhibitors by in vitro assays and in human cancer cells treated with topoisomerase inhibitors.

Cisplatin- and UV-damaged DNA lure the basal transcription factor TFIID/TBP.

Conformational heterogeneity of cytochrome P450 3A4 revealed by high pressure spectroscopy.

Cryo-EM in drug discovery: achievements, limitations and prospects

Effect of the distal residues on the vibrational modes of the Fe-CO bond in hemoglobin studied by protein engineering

Fragment-Based Drug Design: Computational and Experimental State of the Art ⬇️

High affinity of ergopeptides for cytochromes P450 3A. Importance of their peptide moiety for P450 recognition and hydroxylation of bromocriptine

In silico fragment-based drug discovery: setup and validation of a fragment-to-lead computational protocol using S4MPLE.

International Union of Pharmacology. LXVI. Orphan nuclear receptors

One Question, Multiple Answers: Biochemical and Biophysical Screening Methods Retrieve Deviating Fragment Hit Lists

Particular ability of liver P450s3A to catalyze the oxidation of N omega-hydroxyarginine to citrulline and nitrogen oxides and occurrence in no synthases of a sequence very similar to the heme-binding sequence in P450s

Purification of the human RARgamma ligand-binding domain and crystallization of its complex with all-trans retinoic acid.

Recombinant yeast in drug metabolism.

Retinoic acid receptor: a simulation analysis of retinoic acid binding and the resulting conformational changes

Stereochemistry of carbon monoxide binding to normal human adult and Cowtown haemoglobins

Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni

Structural studies on nuclear receptors.

Structure-function analysis of the Rev-erbA and RVR ligand-binding domains reveals a large hydrophobic surface that mediates corepressor binding and a ligand cavity occupied by side chains

Structure-function analysis reveals the molecular determinants of the impaired biological function of DAX-1 mutants in AHC patients

Thermodynamic studies of substrate binding and spin transitions in human cytochrome P-450 3A4 expressed in yeast microsomes.

X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.