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Lista de obras de Manuela Sironi

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

artículo científico publicado en 2020

2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

A 175 million year history of T cell regulatory molecules reveals widespread selection, with adaptive evolution of disease alleles.

artículo científico publicado en 2013

A 6-amino acid insertion/deletion polymorphism in the mucin domain of TIM-1 confers protections against HIV-1 infection.

artículo científico publicado en 2016

A Common Polymorphism in TLR3 Confers Natural Resistance to HIV-1 Infection

article

A clinical, genetic, and biochemical characterization of SPG7 mutations in a large cohort of patients with hereditary spastic paraplegia

artículo científico publicado en 2008

A common genetic variant in FOXP2 is associated with language-based learning (dis)abilities: Evidence from two Italian independent samples

artículo científico publicado en 2017

A complex selection signature at the human AVPR1B gene

artículo científico publicado en 2009

A functional variant in ERAP1 predisposes to multiple sclerosis

artículo científico publicado en 2012

A nonsense polymorphism (R392X) in TLR5 protects from obesity but predisposes to diabetes

artículo científico publicado en 2013

A positively selected APOBEC3H haplotype is associated with natural resistance to HIV-1 infection.

artículo científico publicado en 2011

A region in the dystrophin gene major hot spot harbors a cluster of deletion breakpoints and generates double-strand breaks in yeast

artículo científico publicado en 2006

A regulatory polymorphism in HAVCR2 modulates susceptibility to HIV-1 infection

artículo científico publicado en 2014

A trans-specific polymorphism in ZC3HAV1 is maintained by long-standing balancing selection and may confer susceptibility to multiple sclerosis.

artículo científico publicado en 2012

ABO histo-blood group might modulate predisposition to Crohn's disease and affect disease behavior.

artículo científico publicado en 2013

Adaptation of the endemic coronaviruses HCoV-OC43 and HCoV-229E to the human host

artículo científico publicado en 2021

Albuminoid genes: evolving at the interface of dispensability and selection

artículo científico publicado en 2014

Alternative sources of neurons and glia from somatic stem cells.

artículo científico publicado en 2002

An evolutionary analysis of RAC2 identifies haplotypes associated with human autoimmune diseases.

artículo científico publicado en 2011

An evolutionary analysis of antigen processing and presentation across different timescales reveals pervasive selection

artículo científico publicado en 2014

An evolutionary history of the selectin gene cluster in humans.

artículo científico publicado en 2012

An intragenic deletion/inversion event in the DMD gene determines a novel exon creation and results in a BMD phenotype

artículo científico publicado en 2004

Analysis of Reptarenavirus genomes indicates different selective forces acting on the S and L segments and recent expansion of common genotypes

scholarly article by Chiara Pontremoli published in October 2018

Analysis of intronic conserved elements indicates that functional complexity might represent a major source of negative selection on non-coding sequences

article

Analysis of splicing parameters in the dystrophin gene: relevance for physiological and pathogenetic splicing mechanisms

article

Ancient Evolution of Mammarenaviruses: Adaptation via Changes in the L Protein and No Evidence for Host-Virus Codivergence.

artículo científico publicado en 2018

Ancient and recent selective pressures shaped genetic diversity at AIM2-like nucleic acid sensors.

artículo científico publicado en 2014

Annual (2023) taxonomic update of RNA-directed RNA polymerase-encoding negative-sense RNA viruses (realm Riboviria: kingdom Orthornavirae: phylum Negarnaviricota)

artículo científico publicado en 2023

Antigenic variation of SARS-CoV-2 in response to immune pressure

artículo científico publicado en 2020

Arenavirus genomics: novel insights into viral diversity, origin, and evolution

Arenavirus genomics: novel insights into viral diversity, origin, and evolution

Balancing selection in the extended MHC region maintains a subset of alleles with opposite risk profile for different autoimmune diseases

Balancing selection is common in the extended MHC region but most alleles with opposite risk profile for autoimmune diseases are neutrally evolving

artículo científico publicado en 2011

Both conserved and non-conserved regions of Spo11 are essential for meiotic recombination initiation in yeast

Both selective and neutral processes drive GC content evolution in the human genome

artículo científico publicado en 2008

Chemotactic factors enhance myogenic cell migration across an endothelial monolayer.

artículo científico publicado en 2001

Coding potential and sequence conservation of SARS-CoV-2 and related animal viruses

artículo científico publicado en 2020

Comparative Analysis of Vertebrate Dystrophin Loci Indicate Intron Gigantism as a Common Feature ⬇️

artículo científico publicado el 1 de mayo de 2003

Comparative analysis of the human dystrophin and utrophin gene structures

artículo científico publicado en 2002

Computational inference of selection underlying the evolution of the novel coronavirus, SARS-CoV-2

scientific article published on 01 April 2020

Correction: Signatures of Environmental Genetic Adaptation Pinpoint Pathogens as the Main Selective Pressure through Human Evolution.

artículo científico publicado en 2011

Crohn's disease loci are common targets of protozoa-driven selection

artículo científico publicado en 2013

Determining multiallelic complex copy number and sequence variation from high coverage exome sequencing data

artículo científico publicado en 2015

Distinct selective forces and Neanderthal introgression shaped genetic diversity at genes involved in neurodevelopmental disorders

artículo científico publicado en 2017

Diverse evolutionary histories for beta-adrenoreceptor genes in humans

artículo científico publicado en 2009

Diverse selective regimes shape genetic diversity at ADAR genes and at their coding targets

artículo científico publicado en 2015

Endoplasmic reticulum aminopeptidase 2 haplotypes play a role in modulating susceptibility to HIV infection.

artículo científico publicado en 2013

Evolution and Genetic Diversity of Primate Cytomegaloviruses

artículo científico publicado en 2020

Evolution of the rapidly mutating human salivary agglutinin gene (DMBT1) and population subsistence strategy

artículo científico publicado en 2015

Evolutionary Analysis Provides Insight Into the Origin and Adaptation of HCV.

artículo científico publicado en 2018

Evolutionary analysis identifies an MX2 haplotype associated with natural resistance to HIV-1 infection.

artículo científico publicado en 2014

Evolutionary analysis of Old World arenaviruses reveals a major adaptive contribution of the viral polymerase.

artículo científico publicado en 2017

Evolutionary analysis of the contact system indicates that kininogen evolved adaptively in mammals and in human populations

artículo científico publicado en 2013

Evolutionary genetic dissection of human interferons

artículo científico publicado en 2011

Evolutionary history of copy-number-variable locus for the low-affinity Fcγ receptor: mutation rate, autoimmune disease, and the legacy of helminth infection

artículo científico publicado en 2012

Evolutionary insights into host-pathogen interactions from mammalian sequence data.

artículo científico publicado en 2015

Evolutionary rates of mammalian telomere-stability genes correlate with karyotype features and female germline expression

article

Extensive Positive Selection Drives the Evolution of Nonstructural Proteins in Lineage C Betacoronaviruses

artículo científico publicado en 2016

Fine mapping of AHI1 as a schizophrenia susceptibility gene: from association to evolutionary evidence

artículo científico publicado en 2010

Fixation of conserved sequences shapes human intron size and influences transposon-insertion dynamics

artículo científico publicado en 2005

GeCo++: a C++ library for genomic features computation and annotation in the presence of variants

artículo científico publicado en 2011

Gene function and expression level influence the insertion/fixation dynamics of distinct transposon families in mammalian introns

artículo científico publicado en 2006

Genetic adaptation of the human circadian clock to day-length latitudinal variations and relevance for affective disorders

artículo científico publicado en 2014

Genetic conflicts with Plasmodium parasites and functional constraints shape the evolution of erythrocyte cytoskeletal proteins

artículo científico publicado en 2018

Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection

article

Genetic susceptibility to infectious diseases: Current status and future perspectives from genome-wide approaches.

artículo científico publicado en 2017

Genetic variability at the TREX1 locus is not associated with natural resistance to HIV-1 infection

article

Genetic variability in the ACE gene region surrounding the Alu I/D polymorphism is maintained by balancing selection in human populations

artículo científico publicado en 2010

Genome-wide identification of susceptibility alleles for viral infections through a population genetics approach

artículo científico publicado en 2010

Haptoglobin (HP) and Haptoglobin-related protein (HPR) copy number variation, natural selection, and trypanosomiasis

artículo científico publicado en 2013

Homology‐based classification of accessory proteins in coronavirus genomes uncovers extremely dynamic evolution of gene content

artículo científico publicado en 2022

Human genome variability, natural selection and infectious diseases

artículo científico

Human skin-derived stem cells migrate throughout forebrain and differentiate into astrocytes after injection into adult mouse brain

scientific article published on 01 August 2004

ICTV Virus Taxonomy Profile: Arenaviridae

scientific article published on 13 June 2019

Identification of a new susceptibility variant for multiple sclerosis in OAS1 by population genetics analysis.

artículo científico publicado en 2011

Intraarterial injection of muscle-derived CD34(+)Sca-1(+) stem cells restores dystrophin in mdx mice.

artículo científico publicado en 2001

Intron size in mammals: complexity comes to terms with economy

artículo científico publicado en 2006

Long-standing balancing selection in the THBS4 gene: influence on sex-specific brain expression and gray matter volumes in Alzheimer disease.

artículo científico publicado en 2013

Long-term balancing selection maintains trans-specific polymorphisms in the human TRIM5 gene

artículo científico publicado en 2010

Loss of Dp140 dystrophin isoform and intellectual impairment in Duchenne dystrophy

scientific article published on 01 August 2000

Loss of Dp140 regulatory sequences is associated with cognitive impairment in dystrophinopathies

artículo científico publicado en 2000

Mammalian NPC1 genes may undergo positive selection and human polymorphisms associate with type 2 diabetes

artículo científico publicado en 2012

Molecular Evolution of Human Coronavirus Genomes.

artículo científico publicado en 2016

Molecular analysis of LGMD-2B and MM patients: identification of novel DYSF mutations and possible founder effect in the Italian population

artículo científico publicado en 2003

Multiple Selected Changes May Modulate the Molecular Interaction between Laverania RH5 and Primate Basigin.

artículo científico publicado en 2018

Mutation finding in patients with dysferlin deficiency and role of the dysferlin interacting proteins annexin A1 and A2 in muscular dystrophies

artículo científico publicado en 2005

Natural Selection at the Brush-Border: Adaptations to Carbohydrate Diets in Humans and Other Mammals.

artículo científico publicado en 2015

No association of IFI16 (interferon-inducible protein 16) variants with susceptibility to multiple sclerosis

scientific article published on 16 April 2014

Nonstructural Proteins Are Preferential Positive Selection Targets in Zika Virus and Related Flaviviruses

artículo científico publicado en 2016

OASes and STING: adaptive evolution in concert

artículo científico publicado en 2015

Origin and dispersal of Hepatitis E virus

artículo científico publicado en 2018

Over-representation of exonic splicing enhancers in human intronless genes suggests multiple functions in mRNA processing

article

Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions

artículo científico publicado en 2009

Past and ongoing adaptation of human cytomegalovirus to its host

scientific article published on 08 May 2020

Pathogen-driven selection in the human genome

artículo científico publicado en 2013

Point mutations and a large intragenic deletion in SPG11 in complicated spastic paraplegia without thin corpus callosum.

artículo científico publicado en 2009

Polymorphisms in the CPB2 Gene Are Maintained by Balancing Selection and Result in Haplotype-Preferential Splicing of Exon 7

article

Population genetics of IFIH1: ancient population structure, local selection, and implications for susceptibility to type 1 diabetes

artículo científico publicado en 2010

Population structure of Lassa Mammarenavirus in West Africa

scientific article published on 13 April 2020

Positive Selection Drives Evolution at the Host-Filovirus Interaction Surface

artículo científico publicado en 2016

Positive selection underlies the species-specific binding of Plasmodium falciparum RH5 to human basigin.

artículo científico publicado en 2015

Possible European Origin of Circulating Varicella Zoster Virus Strains

artículo científico publicado en 2020

Possible association between SNAP-25 single nucleotide polymorphisms and alterations of categorical fluency and functional MRI parameters in Alzheimer's disease

artículo científico publicado en 2014

Primary beta-sarcoglycanopathy manifesting as recurrent exercise-induced myoglobinuria

artículo científico publicado en 2001

REST, a master regulator of neurogenesis, evolved under strong positive selection in humans and in non human primates.

artículo científico

RIG-I-like receptors evolved adaptively in mammals, with parallel evolution at LGP2 and RIG-I.

artículo científico publicado en 2013

Recent Out-of-Africa Migration of Human Herpes Simplex Viruses

artículo científico publicado en 2020

Recombination and Positive Selection Differentially Shaped the Diversity of Betacoronavirus Subgenera

scientific article published on 16 November 2020

Relevance of sequence and structure elements for deletion events in the dystrophin gene major hot-spot

artículo científico publicado en 2002

Response to Wilson et al

SARS-CoV-2 and COVID-19: A genetic, epidemiological, and evolutionary perspective

artículo científico publicado en 2020

Signatures of environmental genetic adaptation pinpoint pathogens as the main selective pressure through human evolution

artículo científico publicado en 2011

Silencer elements as possible inhibitors of pseudoexon splicing

artículo científico publicado en 2004

Silencers regulate both constitutive and alternative splicing events in mammals

artículo científico publicado en 2005

Strategy of Human Cytomegalovirus To Escape Interferon Beta-Induced APOBEC3G Editing Activity

scientific article published on 12 September 2018

Susceptibility to type 2 diabetes may be modulated by haplotypes in G6PC2, a target of positive selection.

artículo científico publicado en 2017

TLR3 Mutations in Adult Patients With Herpes Simplex Virus and Varicella-Zoster Virus Encephalitis.

artículo científico publicado en 2017

Taxonomy of the order Bunyavirales: second update 2018

article by Piet Maes et al published 20 January 2019 in Archives of Virology

Taxonomy of the order Bunyavirales: second update 2018

article by Piet Maes et al published March 2019 in Archives of Virology

Taxonomy of the order Bunyavirales: update 2019

The CCR5Δ32 allele is not a major predisposing factor for severe H1N1pdm09 infection.

artículo científico publicado en 2014

The Diversity of Mammalian Hemoproteins and Microbial Heme Scavengers Is Shaped by an Arms Race for Iron Piracy

artículo científico publicado en 2018

The chameleonic genetics of Lassa virus

scientific article published on 03 October 2019

The dystrophin gene is alternatively spliced throughout its coding sequence.

artículo científico publicado en 2002

The evolutionary history of genes involved in spoken and written language: beyond FOXP2.

artículo científico publicado en 2016

The heptad repeat region is a major selection target in MERS-CoV and related coronaviruses.

artículo científico publicado en 2015

The hygiene hypothesis: an evolutionary perspective

artículo científico publicado en 2010

The influence of DCDC2 risk genetic variants on reading: Testing main and haplotypic effects

artículo científico publicado en 2018

The landscape of human genes involved in the immune response to parasitic worms ⬇️

artículo científico publicado el 31 de agosto de 2010

The mammalian complement system as an epitome of host-pathogen genetic conflicts.

artículo científico publicado en 2016

The role of protozoa-driven selection in shaping human genetic variability

artículo científico publicado en 2010

The signature of long-standing balancing selection at the human defensin beta-1 promoter.

artículo científico publicado en 2008

Trans -acting factors may cause dystrophin splicing misregulation in BMD skeletal muscles

article

Transcriptional activation of the non-muscle, full-length dystrophin isoforms in Duchenne muscular dystrophy skeletal muscle.

artículo científico publicado en 2001

Two dystrophin proteins and transcripts in a mild dystrophinopathic patient.

artículo científico publicado en 2003

Variants in SNAP25 are targets of natural selection and influence verbal performances in women.

artículo científico publicado en 2011

Variants in the CYP7B1 gene region do not affect natural resistance to HIV-1 infection.

artículo científico publicado en 2015

Widespread balancing selection and pathogen-driven selection at blood group antigen genes

artículo científico publicado en 2008

You Will Never Walk Alone: Codispersal of JC Polyomavirus with Human Populations

scientific article published on 01 February 2020

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