Lista de obras - Judith M Rollinger - Dominio Público Uruguay

11beta-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches

artículo científico publicado en 2010

1H NMR-MS-based heterocovariance as a drug discovery tool for fishing bioactive compounds out of a complex mixture of structural analogues

scientific article published on 31 July 2019

2-(2,4-dihydroxyphenyl)-5-(E)-propenylbenzofuran promotes endothelial nitric oxide synthase activity in human endothelial cells.

artículo científico publicado en 2012

A Biochemometric Approach for the Identification of In Vitro Anti-Inflammatory Constituents in Masterwort

artículo científico publicado en 2020

A Strength-Weaknesses-Opportunities-Threats (SWOT) Analysis of Cheminformatics in Natural Product Research

artículo científico publicado en 2019

A robust and miniaturized screening platform to study natural products affecting metabolism and survival in Caenorhabditis elegans

artículo científico publicado en 2020

Accessing biological actions of Ganoderma secondary metabolites by in silico profiling

artículo científico publicado en 2015

Acetylcholinesterase inhibitory activity of scopolin and scopoletin discovered by virtual screening of natural products

artículo científico publicado en 2004

Allspice and Clove As Source of Triterpene Acids Activating the G Protein-Coupled Bile Acid Receptor TGR5

artículo científico publicado en 2017

An evaluation of the transition temperature range of super-elastic orthodontic NiTi springs using differential scanning calorimetry

artículo científico publicado en 1999

Anti-Influenza Triterpene Saponins from the Bark of Burkea africana.

artículo científico publicado en 2018

Anti-cancer drug development: computational strategies to identify and target proteins involved in cancer metabolism

artículo científico publicado en 2013

Antipneumococcal activity of neuraminidase inhibiting artocarpin

artículo científico publicado en 2014

Antiviral potential and molecular insight into neuraminidase inhibiting diarylheptanoids from Alpinia katsumadai.

artículo científico publicado en 2010

Application of the in combo screening approach for the discovery of non-alkaloid acetylcholinesterase inhibitors from Cichorium intybus

artículo científico publicado en 2005

Applications of integrated data mining methods to exploring natural product space for acetylcholinesterase inhibitors ⬇️

artículo científico publicado en 2010

Azepine-Indole Alkaloids From Psychotria nemorosa Modulate 5-HT2A Receptors and Prevent in vivo Protein Toxicity in Transgenic Caenorhabditis elegans

artículo científico publicado en 2022

Binary system of (R)- and (S)-nitrendipine--polymorphism and structure

scientific article published on 01 June 1997

Biological Activity of Flavonoids and Rare Sesquiterpene Lactones Isolated From L

scholarly article by Ulrike Grienke et al published 2018 in Frontiers in Pharmacology

Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1.

artículo científico publicado en 2012

Combining ethnopharmacology and virtual screening for lead structure discovery: COX-inhibitors as application example.

artículo científico publicado en 2004

Complementary assays helping to overcome challenges for identifying neuraminidase inhibitors

Computational Chemogenomics

Computational techniques for lead discovery from nature

artículo científico publicado en 2010

Computer-aided discovery, validation, and mechanistic characterization of novel neolignan activators of peroxisome proliferator-activated receptor gamma

artículo científico publicado en 2010

Computer-guided approach to access the anti-influenza activity of licorice constituents

artículo científico

Crystal forms of torasemide: new insights

artículo científico publicado en 2002

Dereplication of depsides from the lichen Pseudevernia furfuracea by centrifugal partition chromatography combined to 13C nuclear magnetic resonance pattern recognition.

artículo científico publicado en 2014

Development of anti-viral agents using molecular modeling and virtual screening techniques

artículo científico publicado en 2011

Discovering COX-inhibiting constituents of Morus root bark: activity-guided versus computer-aided methods

artículo científico publicado en 2005

Discovery and Characterization of Diazenylaryl Sulfonic Acids as Inhibitors of Viral and Bacterial Neuraminidases.

artículo científico publicado en 2017

Discovery and resupply of pharmacologically active plant-derived natural products: A review ⬇️

artículo científico publicado en 2015

Discovery of Bioactive Natural Products for the Treatment of Acute Respiratory Infections - An Integrated Approach.

artículo científico publicado en 2018

Discovery of Novel Natural Neuraminidase Inhibitors (NAI) based on In Silico Screening and Antiviral Investigations

artículo científico

Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP).

artículo científico publicado en 2014

Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniques

artículo científico publicado en 2010

Discovery of depsides and depsidones from lichen as potent inhibitors of microsomal prostaglandin E2 synthase-1 using pharmacophore models

artículo científico publicado en 2012

Discovery of novel CB2 receptor ligands by a pharmacophore-based virtual screening workflow

artículo científico publicado en 2009

Discovery of prenylated flavonoids with dual activity against influenza virus and Streptococcus pneumoniae

artículo científico publicado en 2016

Drugs from nature targeting inflammation (DNTI): a successful Austrian interdisciplinary network project

artículo científico publicado en 2016

Dual Acting Neuraminidase Inhibitors Open New Opportunities to Disrupt the Lethal Synergism between Streptococcus pneumoniae and Influenza Virus.

artículo científico publicado en 2016

Editorial: Ethnopharmacology in Central and Eastern Europe in the Context of Global Research Developments

Effects of the coumarin scopoletin on learning and memory, on release of acetylcholine from brain synaptosomes and on long-term potentiation in hippocampus

European medicinal polypores--a modern view on traditional uses

artículo científico publicado en 2014

Experimentally validated HERG pharmacophore models as cardiotoxicity prediction tools

artículo científico publicado en 2014

Extracts and constituents of Leontopodium alpinum enhance cholinergic transmission: brain ACh increasing and memory improving properties. ⬇️

artículo científico publicado en 2008

Fast and Green - CO2 Based Extraction, Isolation, and Quantification of Phenolic Styrax Constituents

artículo científico publicado en 2017

Fungal strain matters: colony growth and bioactivity of the European medicinal polypores Fomes fomentarius, Fomitopsis pinicola and Piptoporus betulinus

artículo científico publicado en 2015

Ginkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator Biosynthesis

scientific article published on 17 July 2019

High-performance Countercurrent Chromatography to Access Rhodiola rosea Influenza Virus Inhibiting Constituents

artículo científico publicado en 2020

High-performance thin-layer chromatography/bioautography and liquid chromatography-mass spectrometry hyphenated with chemometrics for the quality assessment of Morus alba samples ⬇️

artículo científico publicado en 2019

Honokiol: a non-adipogenic PPARγ agonist from nature

artículo científico publicado en 2013

Human Ether-à-go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids from Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements

artículo científico publicado en 2015

Identification of plumericin as a potent new inhibitor of the NF-κB pathway with anti-inflammatory activity in vitro and in vivo

artículo científico publicado en 2014

Imbricaric acid and perlatolic acid: multi-targeting anti-inflammatory depsides from Cetrelia monachorum ⬇️

artículo científico publicado en 2013

Impact of molecular flexibility on double polymorphism, solid solutions and chiral discrimination during crystallization of diprophylline enantiomers

artículo científico publicado en 2013

In Silico Workflow for the Discovery of Natural Products Activating the G Protein-Coupled Bile Acid Receptor 1.

artículo científico publicado en 2018

In silico Driven Pharmacognosy: Forth, Back and Reverse

scientific article published on 01 April 2015

In silico discovery of acylated flavonol monorhamnosides from Eriobotrya japonica as natural, small-molecular weight inhibitors of XIAP BIR3.

artículo científico publicado en 2010

In silico target fishing for rationalized ligand discovery exemplified on constituents of Ruta graveolens ⬇️

artículo científico publicado en 2008

Influenza neuraminidase: a druggable target for natural products

artículo científico

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 by plant extracts used as traditional antidiabetic medicines.

artículo científico publicado en 2009

Integrated in silico tools for exploiting the natural products' bioactivity.

artículo científico publicado en 2006

Interface dynamics explain assembly dependency of influenza neuraminidase catalytic activity.

artículo científico publicado en 2013

Lanostane Triterpenes from Gloeophyllum odoratum and Their Anti-Influenza Effects ⬇️

artículo científico publicado en 2018

Lignan derivatives from Krameria lappacea roots inhibit acute inflammation in vivo and pro-inflammatory mediators in vitro ⬇️

artículo científico publicado en 2011

Lignans from Carthamus tinctorius suppress tryptophan breakdown via indoleamine 2,3-dioxygenase

artículo científico publicado en 2013

Lignans, phenylpropanoids and polyacetylenes from Chaerophyllum aureum L. (Apiaceae). ⬇️

artículo científico publicado en 2003

Morphinans and isoquinolines: acetylcholinesterase inhibition, pharmacophore modeling, and interaction with opioid receptors.

artículo científico publicado en 2010

Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review

artículo científico publicado en 2014

Natural products against acute respiratory infections: Strategies and lessons learned

scientific article published on 11 October 2019

Natural products in structure-assisted design of molecular cancer therapeutics.

artículo científico publicado en 2010

Natural products modulating the hERG channel: heartaches and hope

artículo científico

Neoandrographolide from Andrographis paniculata as a potential natural chemosensitizer.

artículo científico publicado en 2010

New insights into the acetylcholinesterase inhibitory activity of Lycopodium clavatum.

artículo científico publicado en 2005

Novel neuraminidase inhibitors: identification, biological evaluation and investigations of the binding mode

artículo científico publicado en 2011

Pharmacokinetics of hERG Channel Blocking Voacangine in Wistar Rats Applying a Validated LC-ESI-MS/MS Method.

artículo científico publicado en 2016

Pharmacophore Model Refinement for 11β-Hydroxysteroid Dehydrogenase Inhibitors: Search for Modulators of Intracellular Glucocorticoid Concentrations.

artículo científico publicado en 2013

Pharmacophore modeling and virtual screening for novel acidic inhibitors of microsomal prostaglandin E₂ synthase-1 (mPGES-1)

artículo científico publicado en 2011

Pharmacophore-based discovery of FXR agonists. Part I: Model development and experimental validation

artículo científico publicado en 2011

Pharmacophore-based discovery of FXR-agonists. Part II: identification of bioactive triterpenes from Ganoderma lucidum

artículo científico publicado en 2011

Pharmacophore-based discovery of a novel cytosolic phospholipase A(2)α inhibitor

artículo científico publicado en 2011

Pharmacophore-based virtual screening as a prioritization tool to assess mechanism-based cardiotoxic effects of small organic molecules

scholarly article by Daniela Schuster et al published August 2013 in Toxicology Letters

Piperine Congeners as Inhibitors of Vascular Smooth Muscle Cell Proliferation

artículo científico publicado en 2015

Pistacia lentiscus Oleoresin: Virtual Screening and Identification of Masticadienonic and Isomasticadienonic Acids as Inhibitors of 11β-Hydroxysteroid Dehydrogenase 1.

artículo científico publicado en 2015

Plant extracts in cell-based anti-inflammatory assays—Pitfalls and considerations related to removal of activity masking bulk components

article

Plumeridoid C from the Amazonian traditional medicinal plant Himatanthus sucuuba.

scientific article published on 29 September 2011

Podospermic acid, 1,3,5-tri-O-(7,8-dihydrocaffeoyl)quinic acid from Podospermum laciniatum (Asteraceae)

article published in 2005

Polymorphism of racemic felodipine and the unusual series of solid solutions in the binary system of its enantiomers.

artículo científico publicado en 2001

Predicting Cyclooxygenase Inhibition by Three-Dimensional Pharmacophoric Profiling. Part I: Model Generation, Validation and Applicability in Ethnopharmacology

artículo científico publicado en 2010

Predicting cyclooxygenase inhibition by three-dimensional pharmacophoric profiling. Part II: Identification of enzyme inhibitors from Prasaplai, a Thai traditional medicine

artículo científico publicado en 2010

Preparative supercritical fluid chromatography for lipid class fractionation-a novel strategy in high-resolution mass spectrometry based lipidomics

artículo científico publicado en 2020

Prolongation of metallothionein induction combats Aß and α-synuclein toxicity in aged transgenic Caenorhabditis elegans

scientific article published on 16 July 2020

Quantitative Analysis of Prenylated Constituents in Commercial Hops Samples Using Ultrahigh-Performance Supercritical Fluid Chromatography

artículo científico publicado en 2020

Rapid analytical approach for bioprofiling compounds with radical scavenging and antimicrobial activities from seaweeds

scientific article published on 17 July 2020

Ratanhiaphenol III from Ratanhiae radix is a PTP1B inhibitor.

artículo científico publicado en 2012

Special Issue Dedicated to Professor Dr. Max Wichtl

artículo científico publicado en 2017

Special Issue Dedicated to Professor Dr. Max Wichtl.

artículo científico publicado en 2017

Steroid sulfatase inhibiting lanostane triterpenes - Structure activity relationship and in silico insights

artículo científico publicado en 2019

Strategies for efficient lead structure discovery from natural products.

artículo científico publicado en 2006

Streptomyces spp. From Ethiopia Producing Antimicrobial Compounds: Characterization via Bioassays, Genome Analyses, and Mass Spectrometry ⬇️

artículo científico publicado en 2018

Structure-based virtual screening for the discovery of natural inhibitors for human rhinovirus coat protein

artículo científico publicado en 2008

Taspine: bioactivity-guided isolation and molecular ligand-target insight of a potent acetylcholinesterase inhibitor from Magnolia x soulangiana ⬇️

artículo científico publicado en 2006

The coumarin scopoletin potentiates acetylcholine release from synaptosomes, amplifies hippocampal long-term potentiation and ameliorates anticholinergic- and age-impaired memory ⬇️

artículo científico publicado el 10 de septiembre de 2011

The human rhinovirus: human-pathological impact, mechanisms of antirhinoviral agents, and strategies for their discovery.

artículo científico publicado en 2011

Venturia inaequalis-inhibiting Diels-Alder adducts from Morus root bark

artículo científico publicado en 2006

Virtual screening for the discovery of bioactive natural products

artículo científico publicado en 2008

hERG Channel Blocking Ipecac Alkaloids Identified by Combined In Silico - In Vitro Screening.

artículo científico publicado en 2016

Lista de obras de Judith M Rollinger

11beta-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches

1H NMR-MS-based heterocovariance as a drug discovery tool for fishing bioactive compounds out of a complex mixture of structural analogues

2-(2,4-dihydroxyphenyl)-5-(E)-propenylbenzofuran promotes endothelial nitric oxide synthase activity in human endothelial cells.

A Biochemometric Approach for the Identification of In Vitro Anti-Inflammatory Constituents in Masterwort

A Strength-Weaknesses-Opportunities-Threats (SWOT) Analysis of Cheminformatics in Natural Product Research

A robust and miniaturized screening platform to study natural products affecting metabolism and survival in Caenorhabditis elegans

Accessing biological actions of Ganoderma secondary metabolites by in silico profiling

Acetylcholinesterase inhibitory activity of scopolin and scopoletin discovered by virtual screening of natural products

Allspice and Clove As Source of Triterpene Acids Activating the G Protein-Coupled Bile Acid Receptor TGR5

An evaluation of the transition temperature range of super-elastic orthodontic NiTi springs using differential scanning calorimetry

Anti-Influenza Triterpene Saponins from the Bark of Burkea africana.

Anti-cancer drug development: computational strategies to identify and target proteins involved in cancer metabolism

Antipneumococcal activity of neuraminidase inhibiting artocarpin

Antiviral potential and molecular insight into neuraminidase inhibiting diarylheptanoids from Alpinia katsumadai.

Application of the in combo screening approach for the discovery of non-alkaloid acetylcholinesterase inhibitors from Cichorium intybus

Applications of integrated data mining methods to exploring natural product space for acetylcholinesterase inhibitors ⬇️

Azepine-Indole Alkaloids From Psychotria nemorosa Modulate 5-HT2A Receptors and Prevent in vivo Protein Toxicity in Transgenic Caenorhabditis elegans

Binary system of (R)- and (S)-nitrendipine--polymorphism and structure

Biological Activity of Flavonoids and Rare Sesquiterpene Lactones Isolated From L

Carnosol and carnosic acids from Salvia officinalis inhibit microsomal prostaglandin E2 synthase-1.

Combining ethnopharmacology and virtual screening for lead structure discovery: COX-inhibitors as application example.

Complementary assays helping to overcome challenges for identifying neuraminidase inhibitors

Computational Chemogenomics

Computational techniques for lead discovery from nature

Computer-aided discovery, validation, and mechanistic characterization of novel neolignan activators of peroxisome proliferator-activated receptor gamma

Computer-guided approach to access the anti-influenza activity of licorice constituents

Crystal forms of torasemide: new insights

Dereplication of depsides from the lichen Pseudevernia furfuracea by centrifugal partition chromatography combined to 13C nuclear magnetic resonance pattern recognition.

Development of anti-viral agents using molecular modeling and virtual screening techniques

Discovering COX-inhibiting constituents of Morus root bark: activity-guided versus computer-aided methods

Discovery and Characterization of Diazenylaryl Sulfonic Acids as Inhibitors of Viral and Bacterial Neuraminidases.

Discovery and resupply of pharmacologically active plant-derived natural products: A review ⬇️

Discovery of Bioactive Natural Products for the Treatment of Acute Respiratory Infections - An Integrated Approach.

Discovery of Novel Natural Neuraminidase Inhibitors (NAI) based on In Silico Screening and Antiviral Investigations

Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP).

Discovery of a novel IKK-β inhibitor by ligand-based virtual screening techniques

Discovery of depsides and depsidones from lichen as potent inhibitors of microsomal prostaglandin E2 synthase-1 using pharmacophore models

Discovery of novel CB2 receptor ligands by a pharmacophore-based virtual screening workflow

Discovery of prenylated flavonoids with dual activity against influenza virus and Streptococcus pneumoniae

Drugs from nature targeting inflammation (DNTI): a successful Austrian interdisciplinary network project

Dual Acting Neuraminidase Inhibitors Open New Opportunities to Disrupt the Lethal Synergism between Streptococcus pneumoniae and Influenza Virus.

Editorial: Ethnopharmacology in Central and Eastern Europe in the Context of Global Research Developments

Effects of the coumarin scopoletin on learning and memory, on release of acetylcholine from brain synaptosomes and on long-term potentiation in hippocampus

European medicinal polypores--a modern view on traditional uses

Experimentally validated HERG pharmacophore models as cardiotoxicity prediction tools

Extracts and constituents of Leontopodium alpinum enhance cholinergic transmission: brain ACh increasing and memory improving properties. ⬇️

Fast and Green - CO2 Based Extraction, Isolation, and Quantification of Phenolic Styrax Constituents

Fungal strain matters: colony growth and bioactivity of the European medicinal polypores Fomes fomentarius, Fomitopsis pinicola and Piptoporus betulinus

Ginkgolic Acid is a Multi-Target Inhibitor of Key Enzymes in Pro-Inflammatory Lipid Mediator Biosynthesis

High-performance Countercurrent Chromatography to Access Rhodiola rosea Influenza Virus Inhibiting Constituents

High-performance thin-layer chromatography/bioautography and liquid chromatography-mass spectrometry hyphenated with chemometrics for the quality assessment of Morus alba samples ⬇️

Honokiol: a non-adipogenic PPARγ agonist from nature

Human Ether-à-go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids from Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements

Identification of plumericin as a potent new inhibitor of the NF-κB pathway with anti-inflammatory activity in vitro and in vivo

Imbricaric acid and perlatolic acid: multi-targeting anti-inflammatory depsides from Cetrelia monachorum ⬇️

Impact of molecular flexibility on double polymorphism, solid solutions and chiral discrimination during crystallization of diprophylline enantiomers

In Silico Workflow for the Discovery of Natural Products Activating the G Protein-Coupled Bile Acid Receptor 1.

In silico Driven Pharmacognosy: Forth, Back and Reverse

In silico discovery of acylated flavonol monorhamnosides from Eriobotrya japonica as natural, small-molecular weight inhibitors of XIAP BIR3.

In silico target fishing for rationalized ligand discovery exemplified on constituents of Ruta graveolens ⬇️

Influenza neuraminidase: a druggable target for natural products

Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 by plant extracts used as traditional antidiabetic medicines.

Integrated in silico tools for exploiting the natural products' bioactivity.

Interface dynamics explain assembly dependency of influenza neuraminidase catalytic activity.

Lanostane Triterpenes from Gloeophyllum odoratum and Their Anti-Influenza Effects ⬇️

Lignan derivatives from Krameria lappacea roots inhibit acute inflammation in vivo and pro-inflammatory mediators in vitro ⬇️

Lignans from Carthamus tinctorius suppress tryptophan breakdown via indoleamine 2,3-dioxygenase

Lignans, phenylpropanoids and polyacetylenes from Chaerophyllum aureum L. (Apiaceae). ⬇️

Morphinans and isoquinolines: acetylcholinesterase inhibition, pharmacophore modeling, and interaction with opioid receptors.

Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review

Natural products against acute respiratory infections: Strategies and lessons learned

Natural products in structure-assisted design of molecular cancer therapeutics.

Natural products modulating the hERG channel: heartaches and hope

Neoandrographolide from Andrographis paniculata as a potential natural chemosensitizer.

New insights into the acetylcholinesterase inhibitory activity of Lycopodium clavatum.

Novel neuraminidase inhibitors: identification, biological evaluation and investigations of the binding mode

Pharmacokinetics of hERG Channel Blocking Voacangine in Wistar Rats Applying a Validated LC-ESI-MS/MS Method.

Pharmacophore Model Refinement for 11β-Hydroxysteroid Dehydrogenase Inhibitors: Search for Modulators of Intracellular Glucocorticoid Concentrations.

Pharmacophore modeling and virtual screening for novel acidic inhibitors of microsomal prostaglandin E₂ synthase-1 (mPGES-1)