Lista de obras - Arne Schousboe - Dominio Público Uruguay

1H-cyclopentapyrimidine-2,4(1H,3H)-dione-related ionotropic glutamate receptors ligands. structure-activity relationships and identification of potent and Selective iGluR5 modulators

artículo científico publicado en 2008

40 Year Anniversary Issue of Neurochemical Research.

artículo científico publicado en 2016

A Tribute to Mary C. McKenna: Glutamate as Energy Substrate and Neurotransmitter-Functional Interaction Between Neurons and Astrocytes

artículo científico

A novel selective gamma-aminobutyric acid transport inhibitor demonstrates a functional role for GABA transporter subtype GAT2/BGT-1 in the CNS.

artículo científico publicado en 2006

A subconvulsive dose of kainate selectively compromises astrocytic metabolism in the mouse brain in vivo

artículo científico publicado en 2014

AMPA receptor mediated excitotoxicity in neocortical neurons is developmentally regulated and dependent upon receptor desensitization.

artículo científico publicado en 1998

AMPK Activation Affects Glutamate Metabolism in Astrocytes.

artículo científico publicado en 2015

Activity of the lactate-alanine shuttle is independent of glutamate-glutamine cycle activity in cerebellar neuronal-astrocytic cultures.

artículo científico publicado en 2005

Agonist discrimination between AMPA receptor subtypes.

artículo científico publicado en 2000

Among the branched-chain amino acids, only valine metabolism is up-regulated in astrocytes during glutamate exposure.

artículo científico publicado en 2007

Anaplerosis for Glutamate Synthesis in the Neonate and in Adulthood.

artículo científico publicado en 2016

Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation

artículo científico publicado en 2012

Astrocyte glycogen metabolism is required for neural activity during aglycemia or intense stimulation in mouse white matter.

artículo científico publicado en 2005

Astrocyte glycogenolysis is triggered by store-operated calcium entry and provides metabolic energy for cellular calcium homeostasis

artículo científico publicado en 2014

Astrocytic Control of Biosynthesis and Turnover of the Neurotransmitters Glutamate and GABA ⬇️

artículo científico publicado el 15 de agosto de 2013

Astrocytic GABA Transporters: Pharmacological Properties and Targets for Antiepileptic Drugs

artículo científico publicado en 2017

Astrocytic pyruvate carboxylation: Status after 35 years

scientific article published on 23 February 2019

Brain Alanine Formation as an Ammonia-Scavenging Pathway during Hyperammonemia: Effects of Glutamine Synthetase Inhibition in Rats and Astrocyte—Neuron Co-Cultures ⬇️

artículo científico publicado el 15 de mayo de 2013

Brain glycogen-new perspectives on its metabolic function and regulation at the subcellular level

artículo científico publicado en 2012

Brain glycogen: emergency fuel and dynamic function in neurotransmission

artículo científico publicado en 2014

Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects

artículo científico publicado en 2011

Characterization of depolarization-coupled release of glutamate from cultured mouse cerebellar granule cells using dl-threo-β-benzyloxyaspartate (DL-TBOA) to distinguish between the vesicular and cytoplasmic pools ⬇️

artículo científico publicado el 1 de septiembre de 2003

Characterization of primary and secondary cultures of astrocytes prepared from mouse cerebral cortex.

artículo científico publicado en 2010

Citrate, a Ubiquitous Key Metabolite with Regulatory Function in the CNS.

artículo científico publicado en 2017

Comparison of the agonist binding site of homomeric, heteromeric, and chimeric GluR1o and GluR3o AMPA receptors ⬇️

artículo científico publicado el 15 de julio de 1997

Complex actions of ionomycin in cultured cerebellar astrocytes affecting both calcium-induced calcium release and store-operated calcium entry.

artículo científico publicado en 2013

Complex glutamate labeling from [U-13C]glucose or [U-13C]lactate in co-cultures of cerebellar neurons and astrocytes

artículo científico publicado en 2006

Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice

artículo científico publicado en 2011

Delineation of the Role of Astroglial GABA Transporters in Seizure Control

artículo científico publicado en 2017

Demonstration of extensive GABA synthesis in the small population of GAD positive neurons in cerebellar cultures by the use of pharmacological tools

artículo científico publicado en 2006

Demonstration of neuron-glia transfer of precursors for GABA biosynthesis in a co-culture system of dissociated mouse cerebral cortex

artículo científico publicado en 2008

Depletion of polyamines prevents the neurotrophic activity of the GABA-agonist THIP in cultured rat cerebellar granule cells.

artículo científico publicado en 1993

Depolarization by K+ and glutamate activates different neurotransmitter release mechanisms in GABAergic neurons: vesicular versus non-vesicular release of GABA

scientific article published on 01 June 1993

Depolarization-induced release of [(3)H]D-aspartate from GABAergic neurons caused by reversal of glutamate transporters.

artículo científico publicado en 2000

Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO).

artículo científico publicado en 2003

Determination of the phospholipid precursor of anandamide and other N-acylethanolamine phospholipids before and after sodium azide-induced toxicity in cultured neocortical neurons

artículo científico publicado en 2000

Detoxification of ammonia in mouse cortical GABAergic cell cultures increases neuronal oxidative metabolism and reveals an emerging role for release of glucose-derived alanine

artículo científico publicado en 2010

Development of calcium-permeable ?-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in cultured neocortical neurons visualized by cobalt staining ⬇️

artículo científico publicado el 15 de octubre de 1998

Differential distribution of GABAA receptor subunits in soma and processes of cerebellar granule cells: effects of maturation and a GABA agonist.

artículo científico publicado en 1995

Direct measurement of backflux between oxaloacetate and fumarate following pyruvate carboxylation.

artículo científico publicado en 2011

Discovery of a subtype selective inhibitor of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile.

artículo científico publicado en 2013

Effect of a GABA agonist on the expression and distribution of GABAA receptors in the plasma membrane of cultured cerebellar granule cells: An immunocytochemical study ⬇️

artículo científico publicado el 1 de abril de 1991

Effect of glutamine synthetase inhibition on brain and interorgan ammonia metabolism in bile duct ligated rats

scientific article published on 18 December 2013

Effect of phenylsuccinate on potassium- and ischemia-induced release of glutamate in rat hippocampus monitored by microdialysis ⬇️

artículo científico publicado el 16 de diciembre de 1991

Effects of adrenergic agents on intracellular Ca2+ homeostasis and metabolism of glucose in astrocytes with an emphasis on pyruvate carboxylation, oxidative decarboxylation and recycling: implications for glutamate neurotransmission and excitotoxici

artículo científico publicado en 2011

Effects of gamma-aminobutyric acid (GABA) on synaptogenesis and synaptic function

scientific article published on 01 January 1998

Effects of hyperammonemia on brain energy metabolism: controversial findings in vivo and in vitro.

artículo científico

Effects of inhibitors of protein synthesis and intracellular transport on the gamma-aminobutyric acid agonist-induced functional differentiation of cultured cerebellar granule cells.

artículo científico publicado en 1990

Effects of taurine depletion on cell migration and NCAM expression in cultures of dissociated mouse cerebellum and N2A cells.

artículo científico publicado en 1998

Energy substrates to support glutamatergic and GABAergic synaptic function: role of glycogen, glucose and lactate

artículo científico publicado en 2007

Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP.

artículo científico publicado en 2005

Expression of Glutamate Decarboxylase (GAD) mRNA in the brain of bile duct ligated rats serving as a model of hepatic encephalopathy.

artículo científico publicado en 2013

Expression of glutamine transporter isoforms in cerebral cortex of rats with chronic hepatic encephalopathy.

artículo científico publicado en 2015

Expression of the GABAA receptor ?6 subunit in cultured cerebellar granule cells is developmentally regulated by activation of GABAA receptors ⬇️

artículo científico publicado el 15 de diciembre de 1997

Expression of the human isoform of glutamate dehydrogenase, hGDH2, augments TCA cycle capacity and oxidative metabolism of glutamate during glucose deprivation in astrocytes

artículo científico publicado en 2016

Extensive astrocyte metabolism of γ-aminobutyric acid (GABA) sustains glutamine synthesis in the mammalian cerebral cortex

artículo científico publicado en 2020

First direct electron microscopic visualization of a tight spatial coupling between GABAA-receptors and voltage-sensitive calcium channels

artículo científico publicado el 16 de marzo de 1992

Functional importance of the astrocytic glycogen-shunt and glycolysis for maintenance of an intact intra/extracellular glutamate gradient.

scientific article published on 20 March 2010

Functional significance of brain glycogen in sustaining glutamatergic neurotransmission.

artículo científico publicado en 2009

GABA: homeostatic and pharmacological aspects

artículo científico publicado en 2007

Gamma-aminobutyric acid agonist-induced alterations in the ultrastructure of cultured cerebellar granule cells is restricted to early development

scientific article published on 01 July 1988

Glial GABA Transporters as Modulators of Inhibitory Signalling in Epilepsy and Stroke.

artículo científico publicado en 2017

Glucose is necessary to maintain neurotransmitter homeostasis during synaptic activity in cultured glutamatergic neurons

artículo científico publicado en 2006

Glucose replaces glutamate as energy substrate to fuel glutamate uptake in glutamate dehydrogenase-deficient astrocytes

artículo científico publicado en 2015

Glutamate and ATP at the Interface Between Signaling and Metabolism in Astroglia: Examples from Pathology

artículo científico publicado en 2016

Glutamate and ATP: The Crossroads of Signaling and Metabolism in the Brain

artículo científico publicado en 2014

Glutamate dehydrogenase isoforms with N-terminal (His)6- or FLAG-tag retain their kinetic properties and cellular localization.

artículo científico publicado en 2013

Glutamate metabolism in the brain focusing on astrocytes.

artículo científico publicado en 2014

Glutamate neurotransmission is affected in prenatally stressed offspring

artículo científico publicado en 2015

Glutamate oxidation in astrocytes: Roles of glutamate dehydrogenase and aminotransferases

artículo científico publicado en 2016

Glutamate uptake triggers transporter-mediated GABA release from astrocytes

artículo científico publicado en 2009

Glycogen Shunt Activity and Glycolytic Supercompensation in Astrocytes May Be Distinctly Mediated via the Muscle Form of Glycogen Phosphorylase

artículo científico publicado en 2017

Hepatic encephalopathy is associated with decreased cerebral oxygen metabolism and blood flow, not increased ammonia uptake.

artículo científico publicado en 2013

Hippocampal betaine/GABA transporter mRNA expression is not regulated by inflammation or dehydration post‐status epilepticus ⬇️

artículo científico publicado el 9 de febrero de 2011

Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease

artículo científico publicado en 2021

Identification of amino acid residues in GluR1 responsible for ligand binding and desensitization.

artículo científico publicado en 2001

Impairment of short term memory in rats with hepatic encephalopathy due to bile duct ligation.

artículo científico publicado en 2012

Impairment of the organization of locomotor and exploratory behaviors in bile duct-ligated rats

artículo científico publicado en 2012

Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons

artículo científico publicado en 2011

Interorgan metabolism of ornithine phenylacetate (OP)--a novel strategy for treatment of hyperammonemia

artículo científico publicado en 2012

Introduction to special issue in honor of Professor Povl Krogsgaard-Larsen

artículo científico publicado en 2014

Knockout of GAD65 has major impact on synaptic GABA synthesized from astrocyte-derived glutamine

artículo científico publicado en 2010

Localization and pharmacological characterization of voltage dependent calcium channels in cultured neocortical neurons.

artículo científico publicado en 2001

Low cerebral oxygen consumption and blood flow in patients with cirrhosis and an acute episode of hepatic encephalopathy

artículo científico publicado en 2008

Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating ⬇️

artículo científico publicado el 24 de abril de 2011

Metabolic Characterization of Acutely Isolated Hippocampal and Cerebral Cortical Slices Using [U-13C]Glucose and [1,2-13C]Acetate as Substrates

artículo científico publicado en 2016

Metabolic fate of isoleucine in a rat model of hepatic encephalopathy and in cultured neural cells exposed to ammonia.

artículo científico publicado en 2008

Metabolism of [1,6-(13)C]glucose and [U-(13)C]glutamine and depolarization induced GABA release in superfused mouse cerebral cortical mini-slices.

artículo científico publicado en 2008

Metabolism of [U-13C]glutamine and [U-13C]glutamate in isolated rat brain mitochondria suggests functional phosphate-activated glutaminase activity in matrix

artículo científico publicado en 2007

Molecular determinants of desensitization and assembly of the chimeric GABA(A) receptor subunits (alpha1/gamma2) and (gamma2/alpha1) in combinations with beta2 and gamma2.

artículo científico publicado en 2001

Neuron-glia interactions in glutamatergic neurotransmission: roles of oxidative and glycolytic adenosine triphosphate as energy source

artículo científico

Neuronal Cell Death Induced by Mechanical Percussion Trauma in Cultured Neurons is not Preceded by Alterations in Glucose, Lactate and Glutamine Metabolism.

artículo científico publicado en 2016

Neuronal glucose but not lactate utilization is positively correlated with NMDA-induced neurotransmission and fluctuations in cytosolic Ca2+ levels.

artículo científico publicado en 2009

Neurotransmitter transporters: molecular function of important drug targets

artículo científico publicado en 2006

Novel model of neuronal bioenergetics: postsynaptic utilization of glucose but not lactate correlates positively with Ca2+ signalling in cultured mouse glutamatergic neurons.

artículo científico publicado en 2012

Obesity and type 2 diabetes in rats are associated with altered brain glycogen and amino-acid homeostasis.

artículo científico publicado en 2010

Oxidative metabolism of astrocytes is not reduced in hepatic encephalopathy: a PET study with [(11)C]acetate in humans

artículo científico publicado en 2014

Parallel expression of synaptophysin and evoked neurotransmitter release during development of cultured neurons.

artículo científico publicado en 1991

Partial agonism and antagonism of the ionotropic glutamate receptor iGLuR5: structures of the ligand-binding core in complex with domoic acid and 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid

artículo científico publicado en 2007

Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti-seizure Effects

scientific article published on 04 April 2020

Pharmacological properties of homomeric and heteromeric GluR1o and GluR3o receptors.

artículo científico publicado en 1998

Preface for the Mary C. McKenna Honorary Issue of Neurochemical Research

artículo científico publicado en 2017

Preface for the Ursula Sonnewald Honorary Issue of Neurochemical Research

artículo científico publicado en 2017

Primary cultures of astrocytes: their value in understanding astrocytes in health and disease.

artículo científico publicado en 2012

Procedure for calculation of potency and efficacy for ligands acting on Gs- and Gi-coupled receptors.

artículo científico publicado en 2012

Reply: To PMID 22886493.

artículo científico publicado en 2013

Role of astrocytes in depolarization-coupled release of glutamate in cerebellar cultures

artículo científico publicado en 2004

Role of astrocytic transport processes in glutamatergic and GABAergic neurotransmission.

artículo científico publicado en 2004

Role of branched chain amino acids in cerebral ammonia homeostasis related to hepatic encephalopathy.

artículo científico

Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol.

artículo científico publicado en 2011

Selective mGAT2 (BGT-1) GABA uptake inhibitors: design, synthesis, and pharmacological characterization.

artículo científico publicado en 2013

Special issue on neurotransmitter transporters

scientific article published on 22 November 2019

Specificity of exogenous acetate and glutamate as astrocyte substrates examined in acute brain slices from female mice using methionine sulfoximine (MSO) to inhibit glutamine synthesis

artículo científico publicado en 2017

Spectral components of cytosolic [Ca2+] spiking in neurons ⬇️

artículo científico publicado el 9 de marzo de 1998

State-Dependent Changes in Brain Glycogen Metabolism

scientific article published on 01 January 2019

Stereoselective effects of AMOA on non-NMDA receptors expressed in Xenopus oocytes

artículo científico publicado el 1 de noviembre de 1992

Structure activity relationship of selective GABA uptake inhibitors

artículo científico publicado en 2015

Structure-Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/γ-Aminobutyric Acid Transporter 1 (BGT1).

artículo científico publicado en 2017

Structure-activity relationship and pharmacology of gamma-aminobutyric acid (GABA) transport inhibitors.

artículo científico publicado en 2006

Structure-activity relationships of selective GABA uptake inhibitors.

artículo científico publicado en 2006

Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency

artículo científico publicado en 2008

Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy

artículo científico publicado en 2011

The 11th International Conference on Brain Energy Metabolism "how energy metabolism shapes brain function". Preface

artículo científico publicado en 2015

The 12th International Conference on Brain Energy Metabolism (ICBEM): "Energy Metabolism and Neuron-Glia Interactions in Brain: From Molecular Mechanisms to Novel Therapeutic Approaches".

artículo científico publicado en 2017

The 13th International Conference on Brain Energy Metabolism: "How Metabolism Dictates Neurotransmission, Function and Behavior"

scientific article published on 24 May 2019

The GABA synapse as a target for antiepileptic drugs: a historical overview focused on GABA transporters.

artículo científico publicado en 2014

The Glutamine Transporters and Their Role in the Glutamate/GABA-Glutamine Cycle

artículo científico publicado en 2016

The anticonvulsant action of the galanin receptor agonist NAX-5055 involves modulation of both excitatory- and inhibitory neurotransmission.

artículo científico publicado en 2016

The effect of pH and ADP on ammonia affinity for human glutamate dehydrogenases.

artículo científico publicado en 2013

The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer.

artículo científico publicado en 2006

The glutamine-glutamate/GABA cycle: function, regional differences in glutamate and GABA production and effects of interference with GABA metabolism.

artículo científico publicado en 2014

The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytes

artículo científico publicado en 2007

The novel anticonvulsant neuropeptide and galanin analogue, NAX-5055, does not alter energy and amino acid metabolism in cultured brain cells.

artículo científico publicado en 2017

The structure of a mixed GluR2 ligand-binding core dimer in complex with (S)-glutamate and the antagonist (S)-NS1209.

artículo científico publicado en 2006

The subcellular localization of GABA transporters and its implication for seizure management

scientific article published on 18 December 2014

Tyr702 is an important determinant of agonist binding and domain closure of the ligand-binding core of GluR2.

artículo científico publicado en 2004

Valine but not leucine or isoleucine supports neurotransmitter glutamate synthesis during synaptic activity in cultured cerebellar neurons.

artículo científico publicado en 2012

Lista de obras de Arne Schousboe

1H-cyclopentapyrimidine-2,4(1H,3H)-dione-related ionotropic glutamate receptors ligands. structure-activity relationships and identification of potent and Selective iGluR5 modulators

40 Year Anniversary Issue of Neurochemical Research.

A Tribute to Mary C. McKenna: Glutamate as Energy Substrate and Neurotransmitter-Functional Interaction Between Neurons and Astrocytes

A novel selective gamma-aminobutyric acid transport inhibitor demonstrates a functional role for GABA transporter subtype GAT2/BGT-1 in the CNS.

A subconvulsive dose of kainate selectively compromises astrocytic metabolism in the mouse brain in vivo

AMPA receptor mediated excitotoxicity in neocortical neurons is developmentally regulated and dependent upon receptor desensitization.

AMPK Activation Affects Glutamate Metabolism in Astrocytes.

Activity of the lactate-alanine shuttle is independent of glutamate-glutamine cycle activity in cerebellar neuronal-astrocytic cultures.

Agonist discrimination between AMPA receptor subtypes.

Among the branched-chain amino acids, only valine metabolism is up-regulated in astrocytes during glutamate exposure.

Anaplerosis for Glutamate Synthesis in the Neonate and in Adulthood.

Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation

Astrocyte glycogen metabolism is required for neural activity during aglycemia or intense stimulation in mouse white matter.

Astrocyte glycogenolysis is triggered by store-operated calcium entry and provides metabolic energy for cellular calcium homeostasis

Astrocytic Control of Biosynthesis and Turnover of the Neurotransmitters Glutamate and GABA ⬇️

Astrocytic GABA Transporters: Pharmacological Properties and Targets for Antiepileptic Drugs

Astrocytic pyruvate carboxylation: Status after 35 years

Brain Alanine Formation as an Ammonia-Scavenging Pathway during Hyperammonemia: Effects of Glutamine Synthetase Inhibition in Rats and Astrocyte—Neuron Co-Cultures ⬇️

Brain glycogen-new perspectives on its metabolic function and regulation at the subcellular level

Brain glycogen: emergency fuel and dynamic function in neurotransmission

Branched-chain amino acids increase arterial blood ammonia in spite of enhanced intrinsic muscle ammonia metabolism in patients with cirrhosis and healthy subjects

Characterization of depolarization-coupled release of glutamate from cultured mouse cerebellar granule cells using dl-threo-β-benzyloxyaspartate (DL-TBOA) to distinguish between the vesicular and cytoplasmic pools ⬇️

Characterization of primary and secondary cultures of astrocytes prepared from mouse cerebral cortex.

Citrate, a Ubiquitous Key Metabolite with Regulatory Function in the CNS.

Comparison of the agonist binding site of homomeric, heteromeric, and chimeric GluR1o and GluR3o AMPA receptors ⬇️

Complex actions of ionomycin in cultured cerebellar astrocytes affecting both calcium-induced calcium release and store-operated calcium entry.

Complex glutamate labeling from [U-13C]glucose or [U-13C]lactate in co-cultures of cerebellar neurons and astrocytes

Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice

Delineation of the Role of Astroglial GABA Transporters in Seizure Control

Demonstration of extensive GABA synthesis in the small population of GAD positive neurons in cerebellar cultures by the use of pharmacological tools

Demonstration of neuron-glia transfer of precursors for GABA biosynthesis in a co-culture system of dissociated mouse cerebral cortex

Depletion of polyamines prevents the neurotrophic activity of the GABA-agonist THIP in cultured rat cerebellar granule cells.

Depolarization by K+ and glutamate activates different neurotransmitter release mechanisms in GABAergic neurons: vesicular versus non-vesicular release of GABA

Depolarization-induced release of [(3)H]D-aspartate from GABAergic neurons caused by reversal of glutamate transporters.

Design, synthesis, and pharmacology of a highly subtype-selective GluR1/2 agonist, (RS)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid (Cl-HIBO).

Determination of the phospholipid precursor of anandamide and other N-acylethanolamine phospholipids before and after sodium azide-induced toxicity in cultured neocortical neurons

Detoxification of ammonia in mouse cortical GABAergic cell cultures increases neuronal oxidative metabolism and reveals an emerging role for release of glucose-derived alanine

Development of calcium-permeable ?-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in cultured neocortical neurons visualized by cobalt staining ⬇️

Differential distribution of GABAA receptor subunits in soma and processes of cerebellar granule cells: effects of maturation and a GABA agonist.

Direct measurement of backflux between oxaloacetate and fumarate following pyruvate carboxylation.

Discovery of a subtype selective inhibitor of the human betaine/GABA transporter 1 (BGT-1) with a non-competitive pharmacological profile.

Effect of a GABA agonist on the expression and distribution of GABAA receptors in the plasma membrane of cultured cerebellar granule cells: An immunocytochemical study ⬇️

Effect of glutamine synthetase inhibition on brain and interorgan ammonia metabolism in bile duct ligated rats

Effect of phenylsuccinate on potassium- and ischemia-induced release of glutamate in rat hippocampus monitored by microdialysis ⬇️

Effects of adrenergic agents on intracellular Ca2+ homeostasis and metabolism of glucose in astrocytes with an emphasis on pyruvate carboxylation, oxidative decarboxylation and recycling: implications for glutamate neurotransmission and excitotoxici

Effects of gamma-aminobutyric acid (GABA) on synaptogenesis and synaptic function

Effects of hyperammonemia on brain energy metabolism: controversial findings in vivo and in vitro.

Effects of inhibitors of protein synthesis and intracellular transport on the gamma-aminobutyric acid agonist-induced functional differentiation of cultured cerebellar granule cells.

Effects of taurine depletion on cell migration and NCAM expression in cultures of dissociated mouse cerebellum and N2A cells.

Energy substrates to support glutamatergic and GABAergic synaptic function: role of glycogen, glucose and lactate

Exploring the GluR2 ligand-binding core in complex with the bicyclical AMPA analogue (S)-4-AHCP.

Expression of Glutamate Decarboxylase (GAD) mRNA in the brain of bile duct ligated rats serving as a model of hepatic encephalopathy.

Expression of glutamine transporter isoforms in cerebral cortex of rats with chronic hepatic encephalopathy.

Expression of the GABAA receptor ?6 subunit in cultured cerebellar granule cells is developmentally regulated by activation of GABAA receptors ⬇️

Expression of the human isoform of glutamate dehydrogenase, hGDH2, augments TCA cycle capacity and oxidative metabolism of glutamate during glucose deprivation in astrocytes

Extensive astrocyte metabolism of γ-aminobutyric acid (GABA) sustains glutamine synthesis in the mammalian cerebral cortex

First direct electron microscopic visualization of a tight spatial coupling between GABAA-receptors and voltage-sensitive calcium channels

Functional importance of the astrocytic glycogen-shunt and glycolysis for maintenance of an intact intra/extracellular glutamate gradient.

Functional significance of brain glycogen in sustaining glutamatergic neurotransmission.

GABA: homeostatic and pharmacological aspects

Gamma-aminobutyric acid agonist-induced alterations in the ultrastructure of cultured cerebellar granule cells is restricted to early development

Glial GABA Transporters as Modulators of Inhibitory Signalling in Epilepsy and Stroke.

Glucose is necessary to maintain neurotransmitter homeostasis during synaptic activity in cultured glutamatergic neurons

Glucose replaces glutamate as energy substrate to fuel glutamate uptake in glutamate dehydrogenase-deficient astrocytes

Glutamate and ATP at the Interface Between Signaling and Metabolism in Astroglia: Examples from Pathology

Glutamate and ATP: The Crossroads of Signaling and Metabolism in the Brain

Glutamate dehydrogenase isoforms with N-terminal (His)6- or FLAG-tag retain their kinetic properties and cellular localization.

Glutamate metabolism in the brain focusing on astrocytes.

Glutamate neurotransmission is affected in prenatally stressed offspring

Glutamate oxidation in astrocytes: Roles of glutamate dehydrogenase and aminotransferases

Glutamate uptake triggers transporter-mediated GABA release from astrocytes

Glycogen Shunt Activity and Glycolytic Supercompensation in Astrocytes May Be Distinctly Mediated via the Muscle Form of Glycogen Phosphorylase

Hepatic encephalopathy is associated with decreased cerebral oxygen metabolism and blood flow, not increased ammonia uptake.

Hippocampal betaine/GABA transporter mRNA expression is not regulated by inflammation or dehydration post‐status epilepticus ⬇️

Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer's disease

Identification of amino acid residues in GluR1 responsible for ligand binding and desensitization.

Impairment of short term memory in rats with hepatic encephalopathy due to bile duct ligation.

Impairment of the organization of locomotor and exploratory behaviors in bile duct-ligated rats

Inhibition of glutamine synthesis induces glutamate dehydrogenase-dependent ammonia fixation into alanine in co-cultures of astrocytes and neurons