Lista de obras - Rita De Santis - Dominio Público Uruguay

Anti-Aspergillus fumigatus efficacy of pentraxin 3 alone and in combination with antifungals

artículo científico publicado en 2004

Anti-ErbB2 immunotherapeutics: struggling to make better antibodies for cancer therapy

artículo científico publicado en 2020

Anti-proliferative effect of a triazole derivative (ST1959) on LNCaP human prostate cancer cells through down-regulation of cyclin and androgen receptor expression.

artículo científico publicado en 2011

Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulation

Antibody-based cancer therapies: back to "polyclonals"?

artículo científico publicado en 2004

AvidinOX-anchored biotinylated trastuzumab and pertuzumab induce down-modulation of ErbB2 and tumor cell death at concentrations order of magnitude lower than not-anchored antibodies.

artículo científico publicado en 2017

AvidinOX™ for tissue targeted delivery of biotinylated cells.

artículo científico publicado en 2012

Biochemical and biological characterization of a new oxidized avidin with enhanced tissue binding properties.

artículo científico publicado en 2010

Characterization of therapeutic protein AvidinOX by an integrated analytical approach.

artículo científico publicado en 2017

Chemical linkage to injected tissues is a distinctive property of oxidized avidin

artículo científico publicado en 2011

Clavin, a type-1 ribosome-inactivating protein from Aspergillus clavatus IFO 8605. cDNA isolation, heterologous expression, biochemical and biological characterization of the recombinant protein.

artículo científico publicado en 1996

Comparative activity of Sant7 and anti-IL-6, IL-6R monoclonal antibodies in a murine model of B-cell lymphoma

artículo científico publicado en 2005

Correction: Evaluation of tenascin-C by tenatumomab in T-cell non-Hodgkin lymphomas identifies a new target for radioimmunotherapy.

artículo científico publicado en 2018

Design, synthesis, and in vitro activity of peptidomimetic inhibitors of myeloid differentiation factor 88.

artículo científico publicado en 2008

Dissecting drug and vehicle metabolic effects in rats by a metabonomic approach.

artículo científico publicado en 2006

Effect of PTX3 and voriconazole combination in a rat model of invasive pulmonary aspergillosis.

artículo científico publicado en 2012

Efficacy of PTX3 and posaconazole combination in a rat model of invasive pulmonary aspergillosis

artículo científico publicado en 2014

Efficacy of a nanocochleate-encapsulated 3,5-diaryl-s-triazole derivative in a murine model of graft-versus-host disease.

artículo científico publicado en 2008

Efficacy of aerosol therapy of lung cancer correlates with EGFR paralysis induced by AvidinOX-anchored biotinylated Cetuximab

artículo científico publicado en 2014

Evaluation of a new biotin-DOTA conjugate for pretargeted antibody-guided radioimmunotherapy (PAGRIT)

scientific article published on 06 June 2006

Evaluation of tenascin-C by tenatumomab in T-cell non-Hodgkin lymphomas identifies a new target for radioimmunotherapy.

artículo científico publicado en 2018

Expansion of granulocyte colony-stimulating factor/chemotherapy-mobilized CD34+ hematopoietic progenitors: role of granulocyte-macrophage colony-stimulating factor/erythropoietin hybrid protein (MEN11303) and interleukin-15

artículo científico publicado en 1999

Expression and characterization of a mouse/human chimeric antibody specific for EGF receptor

artículo científico publicado en 1996

Growth inhibition of human ovarian carcinoma by a novel AvidinOX-anchored biotinylated camptothecin derivative

scientific article published on 15 September 2018

Hedgehog pathway inhibitors of the acylthiourea and acylguanidine class show antitumor activity on colon cancer in vitro and in vivo

artículo científico publicado en 2018

Human inhalable antibody fragments neutralizing SARS-CoV-2 variants for COVID-19 therapy

artículo científico publicado en 2022

Identification and refinement of a peptide affinity ligand with unique specificity for a monoclonal anti-tenascin-C antibody by screening of a phage display library.

artículo científico publicado en 2006

Intra-tumor AvidinOX allows efficacy of low dose systemic biotinylated Cetuximab in a model of head and neck cancer.

artículo científico publicado en 2015

Intraoperative avidination for radionuclide therapy: a prospective new development to accelerate radiotherapy in breast cancer

artículo científico publicado en 2007

Intraoperative avidination for radionuclide treatment as a radiotherapy boost in breast cancer: results of a phase II study with (90)Y-labeled biotin.

artículo científico publicado en 2009

Low and high tenascin-expressing tumors are efficiently targeted by ST2146 monoclonal antibody.

artículo científico publicado en 2006

Monovalency unleashes the full therapeutic potential of the DN-30 anti-Met antibody

artículo científico publicado en 2010

Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response

artículo científico publicado en 2002

OXavidin for tissue targeting biotinylated therapeutics. ⬇️

artículo científico publicado en 2009

Overproduction of soluble, extracellular cytotoxin α-sarcin inEscherichia coli ⬇️

artículo científico publicado el 1 de abril de 1998

PTX3 Binds MD-2 and Promotes TRIF-Dependent Immune Protection in Aspergillosis

Pentraxin 3 protects from MCMV infection and reactivation through TLR sensing pathways leading to IRF3 activation

scientific article published on 13 July 2006

Pharmacokinetic and immunogenic behavior of three recombinant human GM-CSF-EPO hybrid proteins in cynomolgus monkeys

artículo científico publicado en 1998

Pharmacological inhibition of TLR9 activation blocks autoantibody production in human B cells from SLE patients.

artículo científico publicado en 2010

Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound

artículo científico publicado en 2007

Preclinical Pharmacology and Safety of a Novel Avidin Derivative for Tissue‐Targeted Delivery of Radiolabelled Biotin ⬇️

artículo científico publicado el 25 de abril de 2011

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor.

artículo científico publicado en 2015

Pretargeted antibody-guided radioimmunotherapy in a child affected by resistant anaplastic large cell lymphoma

scientific article published on 26 July 2007

Purification and characterization of two recombinant human granulocyte colony-stimulating factor glycoforms. Pharmacokinetic and activity studies of single-dose administration in mice.

artículo científico publicado en 1999

Radionuclide Therapy of Unresectable Tumors with AvidinOX and (90)Y-biotinDOTA: Tongue Cancer Paradigm

artículo científico publicado en 2015

Role of Cross-Linking Agents in Determining the Biochemical and Pharmacokinetic Properties of Mgr6−Clavin Immunotoxins

scientific article published on 01 May 1998

Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein

artículo científico publicado en 2006

Simultaneous display of two large proteins on the head and tail of bacteriophage lambda

artículo científico publicado en 2013

Structural characterization and independent folding of a chimeric glycoprotein comprising granulocyte-macrophage colony stimulating factor and erythropoietin sequences

artículo científico publicado el 1 de agosto de 1998

Structural characterization of PTX3 disulfide bond network and its multimeric status in cumulus matrix organization

artículo científico publicado en 2008

Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with C1q and complement activation.

artículo científico publicado en 2006

The fusion protein MEN 11303 (granulocyte-macrophage colony stimulating factor/erythropoietin) acts as a potent inducer of erythropoiesis.

artículo científico publicado en 2000

Therapeutic Use of Avidin Is Not Hampered by Antiavidin Antibodies in Humans ⬇️

artículo científico publicado el 23 de septiembre de 2010

Trastuzumab and docetaxel in a preclinical organotypic breast cancer model using tissue slices from mammary fat pad: Translational relevance

artículo científico publicado en 2015

Trastuzumab and docetaxel in a preclinical organotypic breast cancer model using tissue slices from mammary fat pad: Translational relevance.

artículo científico publicado en 2015

Tumor-infiltrating B lymphocytes as an efficient source of highly specific immunoglobulins recognizing tumor cells.

artículo científico publicado en 2007

Lista de obras de Rita De Santis

Anti-Aspergillus fumigatus efficacy of pentraxin 3 alone and in combination with antifungals

Anti-ErbB2 immunotherapeutics: struggling to make better antibodies for cancer therapy

Anti-proliferative effect of a triazole derivative (ST1959) on LNCaP human prostate cancer cells through down-regulation of cyclin and androgen receptor expression.

Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulation

Antibody-based cancer therapies: back to "polyclonals"?

AvidinOX-anchored biotinylated trastuzumab and pertuzumab induce down-modulation of ErbB2 and tumor cell death at concentrations order of magnitude lower than not-anchored antibodies.

AvidinOX™ for tissue targeted delivery of biotinylated cells.

Biochemical and biological characterization of a new oxidized avidin with enhanced tissue binding properties.

Characterization of therapeutic protein AvidinOX by an integrated analytical approach.

Chemical linkage to injected tissues is a distinctive property of oxidized avidin

Clavin, a type-1 ribosome-inactivating protein from Aspergillus clavatus IFO 8605. cDNA isolation, heterologous expression, biochemical and biological characterization of the recombinant protein.

Comparative activity of Sant7 and anti-IL-6, IL-6R monoclonal antibodies in a murine model of B-cell lymphoma

Correction: Evaluation of tenascin-C by tenatumomab in T-cell non-Hodgkin lymphomas identifies a new target for radioimmunotherapy.

Design, synthesis, and in vitro activity of peptidomimetic inhibitors of myeloid differentiation factor 88.

Dissecting drug and vehicle metabolic effects in rats by a metabonomic approach.

Effect of PTX3 and voriconazole combination in a rat model of invasive pulmonary aspergillosis.

Efficacy of PTX3 and posaconazole combination in a rat model of invasive pulmonary aspergillosis

Efficacy of a nanocochleate-encapsulated 3,5-diaryl-s-triazole derivative in a murine model of graft-versus-host disease.

Efficacy of aerosol therapy of lung cancer correlates with EGFR paralysis induced by AvidinOX-anchored biotinylated Cetuximab

Evaluation of a new biotin-DOTA conjugate for pretargeted antibody-guided radioimmunotherapy (PAGRIT)

Evaluation of tenascin-C by tenatumomab in T-cell non-Hodgkin lymphomas identifies a new target for radioimmunotherapy.

Expansion of granulocyte colony-stimulating factor/chemotherapy-mobilized CD34+ hematopoietic progenitors: role of granulocyte-macrophage colony-stimulating factor/erythropoietin hybrid protein (MEN11303) and interleukin-15

Expression and characterization of a mouse/human chimeric antibody specific for EGF receptor

Growth inhibition of human ovarian carcinoma by a novel AvidinOX-anchored biotinylated camptothecin derivative

Hedgehog pathway inhibitors of the acylthiourea and acylguanidine class show antitumor activity on colon cancer in vitro and in vivo

Human inhalable antibody fragments neutralizing SARS-CoV-2 variants for COVID-19 therapy

Identification and refinement of a peptide affinity ligand with unique specificity for a monoclonal anti-tenascin-C antibody by screening of a phage display library.

Intra-tumor AvidinOX allows efficacy of low dose systemic biotinylated Cetuximab in a model of head and neck cancer.

Intraoperative avidination for radionuclide therapy: a prospective new development to accelerate radiotherapy in breast cancer

Intraoperative avidination for radionuclide treatment as a radiotherapy boost in breast cancer: results of a phase II study with (90)Y-labeled biotin.

Low and high tenascin-expressing tumors are efficiently targeted by ST2146 monoclonal antibody.

Monovalency unleashes the full therapeutic potential of the DN-30 anti-Met antibody

Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response

OXavidin for tissue targeting biotinylated therapeutics. ⬇️

Overproduction of soluble, extracellular cytotoxin α-sarcin inEscherichia coli ⬇️

PTX3 Binds MD-2 and Promotes TRIF-Dependent Immune Protection in Aspergillosis

Pentraxin 3 protects from MCMV infection and reactivation through TLR sensing pathways leading to IRF3 activation

Pharmacokinetic and immunogenic behavior of three recombinant human GM-CSF-EPO hybrid proteins in cynomolgus monkeys

Pharmacological inhibition of TLR9 activation blocks autoantibody production in human B cells from SLE patients.

Pivotal Advance: Inhibition of MyD88 dimerization and recruitment of IRAK1 and IRAK4 by a novel peptidomimetic compound

Preclinical Pharmacology and Safety of a Novel Avidin Derivative for Tissue‐Targeted Delivery of Radiolabelled Biotin ⬇️

Preclinical antitumor activity of ST7612AA1: a new oral thiol-based histone deacetylase (HDAC) inhibitor.

Pretargeted antibody-guided radioimmunotherapy in a child affected by resistant anaplastic large cell lymphoma

Purification and characterization of two recombinant human granulocyte colony-stimulating factor glycoforms. Pharmacokinetic and activity studies of single-dose administration in mice.

Radionuclide Therapy of Unresectable Tumors with AvidinOX and (90)Y-biotinDOTA: Tongue Cancer Paradigm

Role of Cross-Linking Agents in Determining the Biochemical and Pharmacokinetic Properties of Mgr6−Clavin Immunotoxins

Selection, affinity maturation, and characterization of a human scFv antibody against CEA protein

Simultaneous display of two large proteins on the head and tail of bacteriophage lambda

Structural characterization and independent folding of a chimeric glycoprotein comprising granulocyte-macrophage colony stimulating factor and erythropoietin sequences

Structural characterization of PTX3 disulfide bond network and its multimeric status in cumulus matrix organization

Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with C1q and complement activation.

The fusion protein MEN 11303 (granulocyte-macrophage colony stimulating factor/erythropoietin) acts as a potent inducer of erythropoiesis.

Therapeutic Use of Avidin Is Not Hampered by Antiavidin Antibodies in Humans ⬇️

Trastuzumab and docetaxel in a preclinical organotypic breast cancer model using tissue slices from mammary fat pad: Translational relevance

Trastuzumab and docetaxel in a preclinical organotypic breast cancer model using tissue slices from mammary fat pad: Translational relevance.

Tumor-infiltrating B lymphocytes as an efficient source of highly specific immunoglobulins recognizing tumor cells.