Lista de obras - Alain Pruvost - Dominio Público Uruguay

A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation

artículo científico publicado en 2017

A limited sampling strategy based on maximum a posteriori Bayesian estimation for a five-probe phenotyping cocktail

artículo científico publicado en 2015

A simple and rapid LC-MS/MS method for therapeutic drug monitoring of cetuximab: a GPCO-UNICANCER proof of concept study in head-and-neck cancer patients

artículo científico publicado en 2017

A strategy for liquid chromatography/tandem mass spectrometric assays of intracellular drugs: application to the validation of the triphosphorylated anabolite of antiretrovirals in peripheral blood mononuclear cells.

artículo científico publicado en 2003

Activity of Bisnaphthalimidopropyl Derivatives against Trypanosoma brucei

artículo científico publicado en 2016

An optimal LC-MS/MS method for determination of azithromycin in white blood cells: application to pediatric samples

artículo científico publicado en 2014

Association of thymidylate synthase gene polymorphisms with stavudine triphosphate intracellular levels and lipodystrophy

artículo científico publicado en 2011

Biological monitoring of occupational exposure to di(2-ethylhexyl) phthalate: survey of workers exposed to plastisols.

artículo científico publicado en 2007

Characterization of immunoreactive acetyl-Ser-Asp-Lys-Pro in human plasma and urine by liquid chromatography-electrospray mass spectrometry

artículo científico publicado en 2001

Combination of tenofovir and emtricitabine plus efavirenz: in vitro modulation of ABC transporter and intracellular drug accumulation.

artículo científico publicado en 2008

Concentrations of tenofovir and emtricitabine in breast milk of HIV-1-infected women in Abidjan, Cote d'Ivoire, in the ANRS 12109 TEmAA Study, Step 2

artículo científico publicado en 2010

Cytochrome P450-mediated oxidation of glucuronide derivatives: example of estradiol-17beta-glucuronide oxidation to 2-hydroxy-estradiol-17beta-glucuronide by CYP 2C8.

artículo científico publicado en 2004

Detection of Simian Immunodeficiency Virus in Semen, Urethra, and Male Reproductive Organs during Efficient Highly Active Antiretroviral Therapy

artículo científico publicado en 2015

Development and in vivo assessment of a transdermal system for physostigmine

artículo científico publicado el 1 de julio de 1998

Development and validation of an LC/MS/MS assay for mycophenolic acid in human peripheral blood mononuclear cells

artículo científico publicado en 2007

Direct analysis of valsartan or candesartan in human plasma and urines by on-line solid phase extraction coupled to electrospray tandem mass spectrometry.

artículo científico publicado en 2009

Direct determination of phosphorylated intracellular anabolites of stavudine (d4T) by liquid chromatography/tandem mass spectrometry.

artículo científico publicado en 2001

Dodecyl creatine ester-loaded nanoemulsion as a promising therapy for creatine transporter deficiency

scientific article published on 30 April 2019

Drug bioanalysis and biomarker discovery at the Commissariat à l'énergie atomique et aux énergies alternatives

scientific article published on 01 April 2010

Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system

artículo científico publicado en 2020

Emtricitabine: Inhibitor and substrate of multidrug resistance associated protein.

artículo científico publicado en 2008

Evaluation of a six-probe cocktail (caffeine, tolbutamide, omeprazole, dextromethorphan, midazolam, and digoxin) approach to estimate hepatic drug detoxification capability and dosage requirements after a single oral dosing in healthy Chinese volunt

artículo científico publicado en 2022

Evidence and possible consequences of the phosphorylation of nucleoside reverse transcriptase inhibitors in human red blood cells.

artículo científico publicado en 2007

Fate of etiproston, a synthetic analogue of PGF2 alpha, in cows

artículo científico publicado en 1994

High levels of zidovudine (AZT) and its intracellular phosphate metabolites in AZT- and AZT-lamivudine-treated newborns of human immunodeficiency virus-infected mothers

artículo científico publicado en 2008

In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice

scientific article published on 13 August 2019

In vitro primary human and animal cell-based blood-brain barrier models as a screening tool in drug discovery

scientific article published on 15 April 2011

Interferon‐Ribavirin in Association with Stavudine Has No Impact on Plasma Human Immunodeficiency Virus (HIV) Type 1 Level in Patients Coinfected with HIV and Hepatitis C Virus: A CORIST‐ANRS HC1 Trial ⬇️

artículo científico publicado el 9 de mayo de 2003

Intergenerational effects on mouse sperm quality after in utero exposure to acetaminophen and ibuprofen

artículo científico publicado en 2018

Is stavudine triphosphate a natural metabolite of zidovudine?

artículo científico publicado en 2006

Liquid chromatography–tandem mass spectrometry assays for intracellular deoxyribonucleotide triphosphate competitors of nucleoside antiretrovirals ⬇️

artículo científico publicado el 15 de junio de 2003

Measurement of intracellular didanosine and tenofovir phosphorylated metabolites and possible interaction of the two drugs in human immunodeficiency virus-infected patients

artículo científico publicado en 2005

Methotrexate and BAFF interaction prevents immunization against TNF inhibitors

artículo científico publicado en 2018

Microenvironment tailors nTreg structure and function

artículo científico publicado en 2019

Orchestration of Tryptophan‐Kynurenine Pathway, Acute Decompensation, and Acute‐on‐Chronic Liver Failure in Cirrhosis

artículo científico publicado en 2019

Polymorphisms of Pyrimidine Pathway Enzymes Encoding Genes and HLA-B*40∶01 Carriage in Stavudine-Associated Lipodystrophy in HIV-Infected Patients

artículo científico publicado en 2013

Pre-clinical development of a combination microbicide vaginal ring containing dapivirine and darunavir.

artículo científico publicado en 2014

Proof-of-Concept Study of Drug Brain Permeability Between in Vivo Human Brain and an in Vitro iPSCs-Human Blood-Brain Barrier Model

artículo científico publicado en 2019

Quantification of small therapeutic proteins in plasma by liquid chromatography-tandem mass spectrometry: application to an elastase inhibitor EPI-hNE4

scientific article published on 01 April 2006

Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy

scientific article published on August 2016

Sensitive and specific LC-ESI-MS/MS method for the determination of a styrylquinoline, BA011FZ041, a potent HIV anti-integrase agent, in rat plasma

scientific article published on 08 December 2006

Specificity enhancement with LC-positive ESI-MS/MS for the measurement of nucleotides: application to the quantitative determination of carbovir triphosphate, lamivudine triphosphate and tenofovir diphosphate in human peripheral blood mononuclear ce

artículo científico publicado en 2008

The Folate Cycle Enzyme MTHFR is a Critical Regulator of Cell Response to MYC-Targeting Therapies

scientific article published on 21 August 2020

The anti-caspase inhibitor Q-VD-OPH prevents AIDS disease progression in SIV-infected rhesus macaques.

artículo científico publicado en 2018

Unexpected CD4 cell count decline in patients receiving didanosine and tenofovir-based regimens despite undetectable viral load

artículo científico publicado en 2004

Use of the stable isotopes technique to evaluate the bioavailability of a pharmaceutical form of magnesium in man

artículo científico publicado en 1998

Very high concentrations of active intracellular phosphorylated emtricitabine in neonates (ANRS 12109 trial, step 2).

artículo científico publicado en 2011

Virological efficacy of 24-week fozivudine-based regimen in ART-naive patients from Tanzania and Côte d'Ivoire

artículo científico publicado en 2016

Visualization of ribonucleotide reductase catalytic oxidation establishes thioredoxins as its major reductants in yeast

scientific article published on 08 January 2007

Lista de obras de Alain Pruvost

A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation

A limited sampling strategy based on maximum a posteriori Bayesian estimation for a five-probe phenotyping cocktail

A simple and rapid LC-MS/MS method for therapeutic drug monitoring of cetuximab: a GPCO-UNICANCER proof of concept study in head-and-neck cancer patients

A strategy for liquid chromatography/tandem mass spectrometric assays of intracellular drugs: application to the validation of the triphosphorylated anabolite of antiretrovirals in peripheral blood mononuclear cells.

Activity of Bisnaphthalimidopropyl Derivatives against Trypanosoma brucei

An optimal LC-MS/MS method for determination of azithromycin in white blood cells: application to pediatric samples

Association of thymidylate synthase gene polymorphisms with stavudine triphosphate intracellular levels and lipodystrophy

Biological monitoring of occupational exposure to di(2-ethylhexyl) phthalate: survey of workers exposed to plastisols.

Characterization of immunoreactive acetyl-Ser-Asp-Lys-Pro in human plasma and urine by liquid chromatography-electrospray mass spectrometry

Combination of tenofovir and emtricitabine plus efavirenz: in vitro modulation of ABC transporter and intracellular drug accumulation.

Concentrations of tenofovir and emtricitabine in breast milk of HIV-1-infected women in Abidjan, Cote d'Ivoire, in the ANRS 12109 TEmAA Study, Step 2

Cytochrome P450-mediated oxidation of glucuronide derivatives: example of estradiol-17beta-glucuronide oxidation to 2-hydroxy-estradiol-17beta-glucuronide by CYP 2C8.

Detection of Simian Immunodeficiency Virus in Semen, Urethra, and Male Reproductive Organs during Efficient Highly Active Antiretroviral Therapy

Development and in vivo assessment of a transdermal system for physostigmine

Development and validation of an LC/MS/MS assay for mycophenolic acid in human peripheral blood mononuclear cells

Direct analysis of valsartan or candesartan in human plasma and urines by on-line solid phase extraction coupled to electrospray tandem mass spectrometry.

Direct determination of phosphorylated intracellular anabolites of stavudine (d4T) by liquid chromatography/tandem mass spectrometry.

Dodecyl creatine ester-loaded nanoemulsion as a promising therapy for creatine transporter deficiency

Drug bioanalysis and biomarker discovery at the Commissariat à l'énergie atomique et aux énergies alternatives

Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system

Emtricitabine: Inhibitor and substrate of multidrug resistance associated protein.

Evaluation of a six-probe cocktail (caffeine, tolbutamide, omeprazole, dextromethorphan, midazolam, and digoxin) approach to estimate hepatic drug detoxification capability and dosage requirements after a single oral dosing in healthy Chinese volunt

Evidence and possible consequences of the phosphorylation of nucleoside reverse transcriptase inhibitors in human red blood cells.

Fate of etiproston, a synthetic analogue of PGF2 alpha, in cows

High levels of zidovudine (AZT) and its intracellular phosphate metabolites in AZT- and AZT-lamivudine-treated newborns of human immunodeficiency virus-infected mothers

In utero exposure to acetaminophen and ibuprofen leads to intergenerational accelerated reproductive aging in female mice

In vitro primary human and animal cell-based blood-brain barrier models as a screening tool in drug discovery

Interferon‐Ribavirin in Association with Stavudine Has No Impact on Plasma Human Immunodeficiency Virus (HIV) Type 1 Level in Patients Coinfected with HIV and Hepatitis C Virus: A CORIST‐ANRS HC1 Trial ⬇️

Intergenerational effects on mouse sperm quality after in utero exposure to acetaminophen and ibuprofen

Is stavudine triphosphate a natural metabolite of zidovudine?

Liquid chromatography–tandem mass spectrometry assays for intracellular deoxyribonucleotide triphosphate competitors of nucleoside antiretrovirals ⬇️

Measurement of intracellular didanosine and tenofovir phosphorylated metabolites and possible interaction of the two drugs in human immunodeficiency virus-infected patients

Methotrexate and BAFF interaction prevents immunization against TNF inhibitors

Microenvironment tailors nTreg structure and function

Orchestration of Tryptophan‐Kynurenine Pathway, Acute Decompensation, and Acute‐on‐Chronic Liver Failure in Cirrhosis

Polymorphisms of Pyrimidine Pathway Enzymes Encoding Genes and HLA-B*40∶01 Carriage in Stavudine-Associated Lipodystrophy in HIV-Infected Patients

Pre-clinical development of a combination microbicide vaginal ring containing dapivirine and darunavir.

Proof-of-Concept Study of Drug Brain Permeability Between in Vivo Human Brain and an in Vitro iPSCs-Human Blood-Brain Barrier Model

Quantification of small therapeutic proteins in plasma by liquid chromatography-tandem mass spectrometry: application to an elastase inhibitor EPI-hNE4

Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy

Sensitive and specific LC-ESI-MS/MS method for the determination of a styrylquinoline, BA011FZ041, a potent HIV anti-integrase agent, in rat plasma

Specificity enhancement with LC-positive ESI-MS/MS for the measurement of nucleotides: application to the quantitative determination of carbovir triphosphate, lamivudine triphosphate and tenofovir diphosphate in human peripheral blood mononuclear ce

The Folate Cycle Enzyme MTHFR is a Critical Regulator of Cell Response to MYC-Targeting Therapies

The anti-caspase inhibitor Q-VD-OPH prevents AIDS disease progression in SIV-infected rhesus macaques.

Unexpected CD4 cell count decline in patients receiving didanosine and tenofovir-based regimens despite undetectable viral load

Use of the stable isotopes technique to evaluate the bioavailability of a pharmaceutical form of magnesium in man

Very high concentrations of active intracellular phosphorylated emtricitabine in neonates (ANRS 12109 trial, step 2).

Virological efficacy of 24-week fozivudine-based regimen in ART-naive patients from Tanzania and Côte d'Ivoire

Visualization of ribonucleotide reductase catalytic oxidation establishes thioredoxins as its major reductants in yeast