Lista de obras - Brent J Ryan - Dominio Público Uruguay

A novel role for endothelial tetrahydrobiopterin in mitochondrial redox balance

artículo científico publicado en 2017

A requirement for Gch1 and tetrahydrobiopterin in embryonic development

scientific journal article

Autoantibodies to posttranslational modifications in rheumatoid arthritis ⬇️

artículo científico publicado en 2014

C-type natriuretic peptide and natriuretic peptide receptor B signalling inhibits cardiac sympathetic neurotransmission and autonomic function

artículo científico publicado en 2016

Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons.

artículo científico publicado en 2019

Commentary: Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models

artículo científico publicado en 2016

Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model

artículo científico publicado en 2013

Detection and characterization of autoantibodies against modified self-proteins in SLE sera after exposure to reactive oxygen and nitrogen species.

artículo científico publicado en 2014

Detection and isolation of human serum autoantibodies that recognize oxidatively modified autoantigens

artículo científico publicado en 2012

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons.

artículo científico publicado en 2016

Extracellular calreticulin is present in the joints of patients with rheumatoid arthritis and inhibits FasL (CD95L)-mediated apoptosis of T cells

artículo científico publicado en 2010

Haplotype-specific MAPT exon 3 expression regulated by common intronic polymorphisms associated with Parkinsonian disorders.

artículo científico publicado en 2017

Lysosomal perturbations in human dopaminergic neurons derived from induced pluripotent stem cells with PARK2 mutation

artículo científico publicado en 2020

Measurement and meaning of markers of reactive species of oxygen, nitrogen and sulfur in healthy human subjects and patients with inflammatory joint disease.

artículo científico publicado en 2011

Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells

artículo científico publicado en 2018

Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease

artículo científico publicado en 2015

Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function

artículo científico publicado en 2022

Oxidation Resistance 1 Modulates Glycolytic Pathways in the Cerebellum via an Interaction with Glucose-6-Phosphate Isomerase

scientific article published on 15 June 2018

Oxidative and other posttranslational modifications in extracellular vesicle biology

artículo científico publicado en 2015

Oxidative post-translational modifications and their involvement in the pathogenesis of autoimmune diseases.

artículo científico publicado en 2014

PARK2 Mutation Causes Metabolic Disturbances and Impaired Survival of Human iPSC-Derived Neurons

artículo científico publicado en 2019

Parkinson's disease in GTP cyclohydrolase 1 mutation carriers

artículo científico publicado en 2014

Perturbations in RhoA signalling cause altered migration and impaired neuritogenesis in human iPSC-derived neural cells with PARK2 mutation

scientific article published on 21 August 2019

Protein-protein interaction networks identify targets which rescue the MPP+ cellular model of Parkinson's disease

artículo científico publicado en 2015

REST Protects Dopaminergic Neurons from Mitochondrial and α-Synuclein Oligomer Pathology in an Alpha Synuclein Overexpressing BAC-Transgenic Mouse Model

artículo científico publicado en 2021

Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse

artículo científico publicado en 2013

Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes

scientific article published on 29 November 2018

α-Synuclein and mitochondrial bioenergetics regulate tetrahydrobiopterin levels in a human dopaminergic model of Parkinson disease

artículo científico publicado en 2013

Lista de obras de Brent J Ryan

A novel role for endothelial tetrahydrobiopterin in mitochondrial redox balance

A requirement for Gch1 and tetrahydrobiopterin in embryonic development

Autoantibodies to posttranslational modifications in rheumatoid arthritis ⬇️

C-type natriuretic peptide and natriuretic peptide receptor B signalling inhibits cardiac sympathetic neurotransmission and autonomic function

Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson's iPSC-derived dopamine neurons.

Commentary: Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models

Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model

Detection and characterization of autoantibodies against modified self-proteins in SLE sera after exposure to reactive oxygen and nitrogen species.

Detection and isolation of human serum autoantibodies that recognize oxidatively modified autoantigens

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons.

Extracellular calreticulin is present in the joints of patients with rheumatoid arthritis and inhibits FasL (CD95L)-mediated apoptosis of T cells

Haplotype-specific MAPT exon 3 expression regulated by common intronic polymorphisms associated with Parkinsonian disorders.

Lysosomal perturbations in human dopaminergic neurons derived from induced pluripotent stem cells with PARK2 mutation

Measurement and meaning of markers of reactive species of oxygen, nitrogen and sulfur in healthy human subjects and patients with inflammatory joint disease.

Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells

Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease

Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function

Oxidation Resistance 1 Modulates Glycolytic Pathways in the Cerebellum via an Interaction with Glucose-6-Phosphate Isomerase

Oxidative and other posttranslational modifications in extracellular vesicle biology

Oxidative post-translational modifications and their involvement in the pathogenesis of autoimmune diseases.

PARK2 Mutation Causes Metabolic Disturbances and Impaired Survival of Human iPSC-Derived Neurons

Parkinson's disease in GTP cyclohydrolase 1 mutation carriers

Perturbations in RhoA signalling cause altered migration and impaired neuritogenesis in human iPSC-derived neural cells with PARK2 mutation

Protein-protein interaction networks identify targets which rescue the MPP+ cellular model of Parkinson's disease

REST Protects Dopaminergic Neurons from Mitochondrial and α-Synuclein Oligomer Pathology in an Alpha Synuclein Overexpressing BAC-Transgenic Mouse Model

Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse

Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes

α-Synuclein and mitochondrial bioenergetics regulate tetrahydrobiopterin levels in a human dopaminergic model of Parkinson disease