Lista de obras - Lee H Wong - Dominio Público Uruguay

A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes

artículo científico publicado en 2014

ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells

scientific journal article

Active transcription and essential role of RNA polymerase II at the centromere during mitosis

artículo científico publicado en 2012

Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns

scientific journal article

Analysis of mitotic and expression properties of human neocentromere-based transchromosomes in mice

artículo científico publicado en 2004

Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity

artículo científico publicado en 2017

BAC-based PCR fragment microarray: high-resolution detection of chromosomal deletion and duplication breakpoints

artículo científico publicado en 2005

CHK1-driven histone H3.3 serine 31 phosphorylation is important for chromatin maintenance and cell survival in human ALT cancer cells

artículo científico publicado en 2015

Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromere

artículo científico publicado en 2007

Centromere on the move.

artículo científico publicado en 2001

Centromere protein b-null mice display decreasing reproductive performance through successive generations of breeding due to diminishing endometrial glands.

artículo científico publicado en 2004

Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated

artículo científico publicado en 2002

Centromeric chromatin pliability and memory at a human neocentromere.

artículo científico publicado en 2003

Compromised Telomeric Heterochromatin Promotes ALTernative Lengthening of Telomeres.

artículo científico publicado en 2016

Conditional allelic replacement applied to genes encoding the histone variant H3.3 in the mouse

artículo científico publicado en 2013

Construction of neocentromere-based human minichromosomes by telomere-associated chromosomal truncation.

artículo científico publicado en 2001

Contribution of the two genes encoding histone variant h3.3 to viability and fertility in mice

scientific journal article

Detection of cryptic pathogenic copy number variations and constitutional loss of heterozygosity using high resolution SNP microarray analysis in 117 patients referred for cytogenetic analysis and impact on clinical practice.

artículo científico publicado en 2008

Epigenetic Regulation of Telomere Chromatin Integrity in Pluripotent Embryonic Stem Cells ⬇️

artículo científico publicado el 1 de octubre de 2010

Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2.

artículo científico publicado en 2013

Evolutionary dynamics of transposable elements at the centromere

artículo científico publicado en 2004

Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes

artículo científico publicado en 2017

HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse.

artículo científico publicado en 2015

High histone variant H3.3 content in mouse prospermatogonia suggests a role in epigenetic reformatting

artículo científico publicado en 2014

Histone H3.3 incorporation provides a unique and functionally essential telomeric chromatin in embryonic stem cells ⬇️

artículo científico publicado en 2009

Histone variant H3.3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeres

artículo científico publicado en 2015

Human centromere repositioning "in progress"

artículo científico publicado en 2004

IFN-gamma priming up-regulates IFN-stimulated gene factor 3 (ISGF3) components, augmenting responsiveness of IFN-resistant melanoma cells to type I IFNs.

artículo científico publicado en 1998

Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma

scientific article published in Nature Communications

Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma.

artículo científico publicado en 1997

Isolation and characterization of a human STAT1 gene regulatory element. Inducibility by interferon (IFN) types I and II and role of IFN regulatory factor-1.

artículo científico publicado en 2002

LINE retrotransposon RNA is an essential structural and functional epigenetic component of a core neocentromeric chromatin

artículo científico publicado en 2009

Lessons from neocentromeres

artículo científico publicado en 2011

Mutations inhibiting KDM4B drive ALT activation in ATRX-mutated glioblastomas

artículo científico publicado en 2021

New players in heterochromatin silencing: histone variant H3.3 and the ATRX/DAXX chaperone

artículo científico publicado en 2016

Normal DNA methylation dynamics in DICER1-deficient mouse embryonic stem cells

artículo científico publicado en 2012

PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells

scientific journal article

PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX.

artículo científico publicado en 2017

Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation

artículo científico publicado en 2006

Poly(ADP-ribose) polymerase 2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc

artículo científico publicado en 2002

Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers.

artículo científico publicado en 2018

The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity

artículo científico publicado en 2014

The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals

artículo científico publicado en 1996

Transcription in the maintenance of centromere chromatin identity

artículo científico publicado en 2012

Transcription within a functional human centromere

artículo científico publicado en 2003

UBF levels determine the number of active ribosomal RNA genes in mammals

scientific journal article

Variable and hierarchical size distribution of L1-retroelement-enriched CENP-A clusters within a functional human neocentromere

artículo científico publicado en 2005

Lista de obras de Lee H Wong

A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes

ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells

Active transcription and essential role of RNA polymerase II at the centromere during mitosis

Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns

Analysis of mitotic and expression properties of human neocentromere-based transchromosomes in mice

Aurora Kinase B, a novel regulator of TERF1 binding and telomeric integrity

BAC-based PCR fragment microarray: high-resolution detection of chromosomal deletion and duplication breakpoints

CHK1-driven histone H3.3 serine 31 phosphorylation is important for chromatin maintenance and cell survival in human ALT cancer cells

Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromere

Centromere on the move.

Centromere protein b-null mice display decreasing reproductive performance through successive generations of breeding due to diminishing endometrial glands.

Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated

Centromeric chromatin pliability and memory at a human neocentromere.

Compromised Telomeric Heterochromatin Promotes ALTernative Lengthening of Telomeres.

Conditional allelic replacement applied to genes encoding the histone variant H3.3 in the mouse

Construction of neocentromere-based human minichromosomes by telomere-associated chromosomal truncation.

Contribution of the two genes encoding histone variant h3.3 to viability and fertility in mice

Detection of cryptic pathogenic copy number variations and constitutional loss of heterozygosity using high resolution SNP microarray analysis in 117 patients referred for cytogenetic analysis and impact on clinical practice.

Epigenetic Regulation of Telomere Chromatin Integrity in Pluripotent Embryonic Stem Cells ⬇️

Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2.

Evolutionary dynamics of transposable elements at the centromere

Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes

HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse.

High histone variant H3.3 content in mouse prospermatogonia suggests a role in epigenetic reformatting

Histone H3.3 incorporation provides a unique and functionally essential telomeric chromatin in embryonic stem cells ⬇️

Histone variant H3.3 provides the heterochromatic H3 lysine 9 tri-methylation mark at telomeres

Human centromere repositioning "in progress"

IFN-gamma priming up-regulates IFN-stimulated gene factor 3 (ISGF3) components, augmenting responsiveness of IFN-resistant melanoma cells to type I IFNs.

Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma

Interferon-resistant human melanoma cells are deficient in ISGF3 components, STAT1, STAT2, and p48-ISGF3gamma.

Isolation and characterization of a human STAT1 gene regulatory element. Inducibility by interferon (IFN) types I and II and role of IFN regulatory factor-1.

LINE retrotransposon RNA is an essential structural and functional epigenetic component of a core neocentromeric chromatin

Lessons from neocentromeres

Mutations inhibiting KDM4B drive ALT activation in ATRX-mutated glioblastomas

New players in heterochromatin silencing: histone variant H3.3 and the ATRX/DAXX chaperone

Normal DNA methylation dynamics in DICER1-deficient mouse embryonic stem cells

PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells

PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX.

Permissive transcriptional activity at the centromere through pockets of DNA hypomethylation

Poly(ADP-ribose) polymerase 2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc

Ribosomal DNA copy loss and repeat instability in ATRX-mutated cancers.

The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrity

The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals

Transcription in the maintenance of centromere chromatin identity

Transcription within a functional human centromere

UBF levels determine the number of active ribosomal RNA genes in mammals

Variable and hierarchical size distribution of L1-retroelement-enriched CENP-A clusters within a functional human neocentromere