Lista de obras - Dena Lyras - Dominio Público Uruguay

A dynamic, ring-forming MucB / RseB-like protein influences spore shape in Bacillus subtilis

scientific article published on 14 December 2020

A mouse model of Staphylococcus aureus small intestinal infection

artículo científico publicado en 2020

A series of three cases of severe Clostridium difficile infection in Australia associated with a binary toxin producing clade 2 ribotype 251 strain

scientific article published on 27 November 2018

Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.

artículo científico publicado en 2015

Antibacterial activity of rhodomyrtone on Clostridium difficile vegetative cells and spores in vitro

artículo científico publicado en 2018

Antibiotic resistance, virulence factors and genetics of Clostridium sordellii

artículo científico

Binaphthyl-1,2,3-triazole peptidomimetics with activity against Clostridium difficile and other pathogenic bacteria.

artículo científico publicado en 2015

Bovine antibodies targeting primary and recurrent Clostridium difficile disease are a potent antibiotic alternative

artículo científico publicado en 2017

CYP101J2, CYP101J3, and CYP101J4, 1,8-Cineole-Hydroxylating Cytochrome P450 Monooxygenases from Sphingobium yanoikuyae Strain B2.

artículo científico publicado en 2016

CdtR Regulates TcdA and TcdB Production in Clostridium difficile

artículo científico publicado en 2016

Cephamycins inhibit pathogen sporulation and effectively treat recurrent Clostridioides difficile infection

scientific article published on 12 August 2019

Characterization of a Tra 2 function of RP1 that affects growth of Pseudomonas aeruginosa PAO and surface exclusion in Escherichia coli K12

scientific article published on 01 March 1992

Characterization of the ends and target sites of the novel conjugative transposon Tn5397 from Clostridium difficile: excision and circularization is mediated by the large resolvase, TndX.

artículo científico publicado en 2000

Chloramphenicol-resistant Neisseria meningitidis containing catP isolated in Australia.

artículo científico publicado en 2003

Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease

artículo científico publicado en 2020

Clostridium difficile drug pipeline: challenges in discovery and development of new agents

artículo científico publicado en 2015

Clostridium difficile toxins induce VEGF-A and vascular permeability to promote disease pathogenesis

scientific article published on 03 December 2018

Clostridium perfringens-mediated necrotic enteritis is not influenced by the pre-existing microbiota but is promoted by large changes in the post-challenge microbiota

scientific article published on 01 November 2018

Clostridium sordellii Pathogenicity Locus Plasmid pCS1-1 Encodes a Novel Clostridial Conjugation Locus

artículo científico publicado en 2018

Clostridium sordellii genome analysis reveals plasmid localized toxin genes encoded within pathogenicity loci

artículo científico publicado en 2015

Clostridium sordellii outer spore proteins maintain spore structural integrity and promote bacterial clearance from the gastrointestinal tract.

artículo científico publicado en 2018

Comparing the identification of Clostridium spp. by two Matrix-Assisted Laser Desorption Ionization-Time of Flight (MALDI-TOF) mass spectrometry platforms to 16S rRNA PCR sequencing as a reference standard: a detailed analysis of age of culture and

Conjugation-mediated horizontal gene transfer of Clostridium perfringens plasmids in the chicken gastrointestinal tract results in the formation of new virulent strains.

artículo científico publicado en 2017

Conjugative transfer of RP4-oriT shuttle vectors from Escherichia coli to Clostridium perfringens.

artículo científico publicado en 1998

Construction and analysis of chromosomal Clostridium difficile mutants

artículo científico publicado en 2006

Cross-complementation of Clostridium perfringens PLC and Clostridium septicum alpha-toxin mutants reveals PLC is sufficient to mediate gas gangrene.

artículo científico publicado en 2009

Crystal structure of a β-aminopeptidase from an Australian Burkholderia sp.

artículo científico publicado en 2017

Defining the Roles of TcdA and TcdB in Localized Gastrointestinal Disease, Systemic Organ Damage, and the Host Response during Clostridium difficile Infections

artículo científico publicado en 2015

Disruption of the Gut Microbiome: Clostridium difficile Infection and the Threat of Antibiotic Resistance

artículo científico publicado en 2015

Diverse bacterial species contribute to antibiotic-associated diarrhoea and gastrointestinal damage

artículo científico publicado en 2018

Emergence of a ribotype 244 strain of Clostridium difficile associated with severe disease and related to the epidemic ribotype 027 strain

artículo científico publicado en 2014

Emergence of toxin A-negative, toxin B-positive Clostridium difficile strains: epidemiological and clinical considerations.

artículo científico publicado en 2015

Environmental response and autoregulation of Clostridium difficile TxeR, a sigma factor for toxin gene expression.

artículo científico publicado en 2002

Epidemics of diarrhea caused by a clindamycin-resistant strain of Clostridium difficile in four hospitals

artículo científico publicado en 1999

Epsilon Toxin Is Essential for the Virulence of Clostridium perfringens Type D Infection in Sheep, Goats, and Mice ⬇️

artículo científico publicado el 29 de abril de 2013

Evidence that compatibility of closely related replicons in Clostridium perfringens depends on linkage to parMRC-like partitioning systems of different subfamilies

artículo científico publicado en 2017

Expansion of the Clostridium perfringens toxin-based typing scheme

artículo científico publicado en 2018

Expression of the large clostridial toxins is controlled by conserved regulatory mechanisms

artículo científico publicado en 2014

Extrachromosomal and integrated genetic elements in Clostridium difficile.

artículo científico

Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation. ⬇️

artículo científico publicado en 2016

Functional analysis of an feoB mutant in Clostridium perfringens strain 13.

artículo científico publicado en 2016

Functional identification of conjugation and replication regions of the tetracycline resistance plasmid pCW3 from Clostridium perfringens

artículo científico publicado en 2006

Genomic analysis of the erythromycin resistance element Tn5398 from Clostridium difficile.

artículo científico publicado en 2001

Genomic diversity of necrotic enteritis-associated strains of Clostridium perfringens: a review

artículo científico publicado en 2016

Identification of essential residues in the Erm(B) rRNA methyltransferase of Clostridium perfringens

artículo científico publicado en 2002

Identification of large cryptic plasmids in Clostridioides (Clostridium) difficile

artículo científico publicado en 2018

Identification of the structural and functional domains of the large serine recombinase TnpX from Clostridium perfringens

artículo científico publicado en 2004

In silico, in vitro and in vivo analysis of putative virulence factors identified in large clostridial toxin-negative, binary toxin- producing C. difficile strains

scientific article published on 01 August 2019

Induction of pCW3-encoded tetracycline resistance in Clostridium perfringens involves a host-encoded factor.

artículo científico publicado en 2001

Influence of gastric acid on susceptibility to infection with ingested bacterial pathogens

artículo científico publicado en 2007

International Society for Plasmid Biology.

artículo científico publicado en 2015

Intestinal Colonization Traits of Pandemic Multidrug-Resistant Escherichia coli ST131.

artículo científico publicado en 2018

Involvement of Bacteria Other Than Clostridium difficile in Antibiotic-Associated Diarrhoea.

artículo científico publicado en 2016

Lectin Activity of the TcdA and TcdB Toxins of Clostridium difficile

artículo científico publicado en 2019

Methods for Determining Transfer of Mobile Genetic Elements in Clostridium difficile

artículo científico publicado en 2016

Methods for Gene Cloning and Targeted Mutagenesis

article

Molecular characterization and antimicrobial susceptibilities of Clostridium difficile clinical isolates from Victoria, Australia

artículo científico publicado en 2015

Necrotic Enteritis in Chickens Associated with Clostridium sordellii

artículo científico publicado en 2015

Novel molecular type of Clostridium difficile in neonatal pigs, Western Australia

artículo científico publicado en 2013

Novel use of tryptose sulfite cycloserine egg yolk agar for isolation of Clostridium perfringens during an outbreak of necrotizing enterocolitis in a neonatal unit

artículo científico publicado en 2010

Opioid analgesics stop the development of clostridial gas gangrene

artículo científico publicado en 2014

Options for improving effectiveness of rotavirus vaccines in developing countries.

artículo científico publicado en 2016

Paeniclostridium sordellii and Clostridioides difficile encode similar and clinically relevant tetracycline resistance loci in diverse genomic locations

scientific article published on 04 March 2019

Plasmid partitioning systems of conjugative plasmids from Clostridium perfringens.

artículo científico publicado en 2015

Pore-forming activity of alpha-toxin is essential for clostridium septicum-mediated myonecrosis.

artículo científico publicado en 2009

Preface: ClostPath 2013 meeting on The Molecular Biology and Pathogenesis of the Clostridia special issue

artículo científico publicado en 2014

Regulation of toxin production in the pathogenic clostridia.

artículo científico

Reply to: Caution is warranted in using cephamycin antibiotics against recurrent Clostridioides difficile infection

scientific article published on 27 January 2020

Small animal models for the study of Clostridium difficile disease pathogenesis.

artículo científico

Solution structure and DNA binding of the catalytic domain of the large serine resolvase TnpX.

artículo científico

Spo0A differentially regulates toxin production in evolutionarily diverse strains of Clostridium difficile

artículo científico publicado en 2013

Structural Characterization of Clostridium sordellii Spores of Diverse Human, Animal, and Environmental Origin and Comparison to Clostridium difficile Spores.

artículo científico publicado en 2017

Synthesis and antimicrobial activity of binaphthyl-based, functionalized oxazole and thiazole peptidomimetics

artículo científico publicado en 2015

TcdB or not TcdB: a tale of two Clostridium difficile toxins.

artículo científico publicado en 2011

TcpM: a novel relaxase that mediates transfer of large conjugative plasmids from Clostridium perfringens

artículo científico publicado en 2015

TcsL is an essential virulence factor in Clostridium sordellii ATCC 9714

artículo científico publicado en 2011

The Clostridium perfringens Tet P determinant comprises two overlapping genes: tetA(P), which mediates active tetracycline efflux, and tetB(P), which is related to the ribosomal protection family of tetracycline-resistance determinants.

artículo científico publicado en 1994

The NanI and NanJ sialidases of Clostridium perfringens are not essential for virulence

artículo científico publicado en 2009

The Sialidase NanS Enhances Non-TcsL Mediated Cytotoxicity of Clostridium sordellii

artículo científico publicado en 2016

The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile

artículo científico publicado en 2011

The binary toxin CDT enhances Clostridium difficile virulence by suppressing protective colonic eosinophilia

artículo científico publicado en 2016

The conjugation protein TcpC from Clostridium perfringens is structurally related to the type IV secretion system protein VirB8 from Gram-negative bacteria

artículo científico publicado en 2012

The cysteine protease α-clostripain is not essential for the pathogenesis of Clostridium perfringens-mediated myonecrosis.

artículo científico publicado en 2011

The large resolvase TnpX is the only transposon-encoded protein required for transposition of the Tn4451/3 family of integrative mobilizable elements.

artículo científico publicado en 2004

The macrolide-lincosamide-streptogramin B resistance determinant from Clostridium difficile 630 contains two erm(B) genes

artículo científico publicado en 2000

The peptidoglycan hydrolase TcpG is required for efficient conjugative transfer of pCW3 in Clostridium perfringens

artículo científico publicado en 2012

The pore-forming α-toxin from clostridium septicum activates the MAPK pathway in a Ras-c-Raf-dependent and independent manner

artículo científico publicado en 2015

The role of toxin A and toxin B in Clostridium difficile-associated disease: Past and present perspectives.

artículo científico publicado en 2010

The α-toxin ofClostridium septicumis essential for virulence

article

Toxin B is essential for virulence of Clostridium difficile

artículo científico publicado en 2009

Transcriptional analysis of the tet(P) operon from Clostridium perfringens.

artículo científico publicado en 2001

Translocation and dissemination of commensal bacteria in post-stroke infection.

artículo científico publicado en 2016

Two distinct regions of the large serine recombinase TnpX are required for DNA binding and biological function

artículo científico publicado en 2006

Utility of the clostridial site-specific recombinase TnpX to clone toxic-product-encoding genes and selectively remove genomic DNA fragments

artículo científico publicado en 2014

Whole genome analysis reveals the diversity and evolutionary relationships between necrotic enteritis-causing strains of Clostridium perfringens.

artículo científico publicado en 2018

X-ray crystal structure of cytochrome P450 monooxygenase CYP101J2 from Sphingobium yanoikuyae strain B2.

artículo científico publicado en 2016

tISCpe8, an IS1595-family lincomycin resistance element located on a conjugative plasmid in Clostridium perfringens.

scientific article published on 14 August 2009

β-Aminopeptidases: Insight into Enzymes without a Known Natural Substrate

scientific article published on 18 July 2019

Lista de obras de Dena Lyras

A dynamic, ring-forming MucB / RseB-like protein influences spore shape in Bacillus subtilis

A mouse model of Staphylococcus aureus small intestinal infection

A series of three cases of severe Clostridium difficile infection in Australia associated with a binary toxin producing clade 2 ribotype 251 strain

Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.

Antibacterial activity of rhodomyrtone on Clostridium difficile vegetative cells and spores in vitro

Antibiotic resistance, virulence factors and genetics of Clostridium sordellii

Binaphthyl-1,2,3-triazole peptidomimetics with activity against Clostridium difficile and other pathogenic bacteria.

Bovine antibodies targeting primary and recurrent Clostridium difficile disease are a potent antibiotic alternative

CYP101J2, CYP101J3, and CYP101J4, 1,8-Cineole-Hydroxylating Cytochrome P450 Monooxygenases from Sphingobium yanoikuyae Strain B2.

CdtR Regulates TcdA and TcdB Production in Clostridium difficile

Cephamycins inhibit pathogen sporulation and effectively treat recurrent Clostridioides difficile infection

Characterization of a Tra 2 function of RP1 that affects growth of Pseudomonas aeruginosa PAO and surface exclusion in Escherichia coli K12

Characterization of the ends and target sites of the novel conjugative transposon Tn5397 from Clostridium difficile: excision and circularization is mediated by the large resolvase, TndX.

Chloramphenicol-resistant Neisseria meningitidis containing catP isolated in Australia.

Clostridioides difficile infection damages colonic stem cells via TcdB, impairing epithelial repair and recovery from disease

Clostridium difficile drug pipeline: challenges in discovery and development of new agents

Clostridium difficile toxins induce VEGF-A and vascular permeability to promote disease pathogenesis

Clostridium perfringens-mediated necrotic enteritis is not influenced by the pre-existing microbiota but is promoted by large changes in the post-challenge microbiota

Clostridium sordellii Pathogenicity Locus Plasmid pCS1-1 Encodes a Novel Clostridial Conjugation Locus

Clostridium sordellii genome analysis reveals plasmid localized toxin genes encoded within pathogenicity loci

Clostridium sordellii outer spore proteins maintain spore structural integrity and promote bacterial clearance from the gastrointestinal tract.

Comparing the identification of Clostridium spp. by two Matrix-Assisted Laser Desorption Ionization-Time of Flight (MALDI-TOF) mass spectrometry platforms to 16S rRNA PCR sequencing as a reference standard: a detailed analysis of age of culture and

Conjugation-mediated horizontal gene transfer of Clostridium perfringens plasmids in the chicken gastrointestinal tract results in the formation of new virulent strains.

Conjugative transfer of RP4-oriT shuttle vectors from Escherichia coli to Clostridium perfringens.

Construction and analysis of chromosomal Clostridium difficile mutants

Cross-complementation of Clostridium perfringens PLC and Clostridium septicum alpha-toxin mutants reveals PLC is sufficient to mediate gas gangrene.

Crystal structure of a β-aminopeptidase from an Australian Burkholderia sp.

Defining the Roles of TcdA and TcdB in Localized Gastrointestinal Disease, Systemic Organ Damage, and the Host Response during Clostridium difficile Infections

Disruption of the Gut Microbiome: Clostridium difficile Infection and the Threat of Antibiotic Resistance

Diverse bacterial species contribute to antibiotic-associated diarrhoea and gastrointestinal damage

Emergence of a ribotype 244 strain of Clostridium difficile associated with severe disease and related to the epidemic ribotype 027 strain

Emergence of toxin A-negative, toxin B-positive Clostridium difficile strains: epidemiological and clinical considerations.

Environmental response and autoregulation of Clostridium difficile TxeR, a sigma factor for toxin gene expression.

Epidemics of diarrhea caused by a clindamycin-resistant strain of Clostridium difficile in four hospitals

Epsilon Toxin Is Essential for the Virulence of Clostridium perfringens Type D Infection in Sheep, Goats, and Mice ⬇️

Evidence that compatibility of closely related replicons in Clostridium perfringens depends on linkage to parMRC-like partitioning systems of different subfamilies

Expansion of the Clostridium perfringens toxin-based typing scheme

Expression of the large clostridial toxins is controlled by conserved regulatory mechanisms

Extrachromosomal and integrated genetic elements in Clostridium difficile.

Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation. ⬇️

Functional analysis of an feoB mutant in Clostridium perfringens strain 13.

Functional identification of conjugation and replication regions of the tetracycline resistance plasmid pCW3 from Clostridium perfringens

Genomic analysis of the erythromycin resistance element Tn5398 from Clostridium difficile.

Genomic diversity of necrotic enteritis-associated strains of Clostridium perfringens: a review

Identification of essential residues in the Erm(B) rRNA methyltransferase of Clostridium perfringens

Identification of large cryptic plasmids in Clostridioides (Clostridium) difficile

Identification of the structural and functional domains of the large serine recombinase TnpX from Clostridium perfringens

In silico, in vitro and in vivo analysis of putative virulence factors identified in large clostridial toxin-negative, binary toxin- producing C. difficile strains

Induction of pCW3-encoded tetracycline resistance in Clostridium perfringens involves a host-encoded factor.

Influence of gastric acid on susceptibility to infection with ingested bacterial pathogens

International Society for Plasmid Biology.

Intestinal Colonization Traits of Pandemic Multidrug-Resistant Escherichia coli ST131.

Involvement of Bacteria Other Than Clostridium difficile in Antibiotic-Associated Diarrhoea.

Lectin Activity of the TcdA and TcdB Toxins of Clostridium difficile

Methods for Determining Transfer of Mobile Genetic Elements in Clostridium difficile

Methods for Gene Cloning and Targeted Mutagenesis

Molecular characterization and antimicrobial susceptibilities of Clostridium difficile clinical isolates from Victoria, Australia

Necrotic Enteritis in Chickens Associated with Clostridium sordellii

Novel molecular type of Clostridium difficile in neonatal pigs, Western Australia

Novel use of tryptose sulfite cycloserine egg yolk agar for isolation of Clostridium perfringens during an outbreak of necrotizing enterocolitis in a neonatal unit

Opioid analgesics stop the development of clostridial gas gangrene

Options for improving effectiveness of rotavirus vaccines in developing countries.

Paeniclostridium sordellii and Clostridioides difficile encode similar and clinically relevant tetracycline resistance loci in diverse genomic locations

Plasmid partitioning systems of conjugative plasmids from Clostridium perfringens.

Pore-forming activity of alpha-toxin is essential for clostridium septicum-mediated myonecrosis.

Preface: ClostPath 2013 meeting on The Molecular Biology and Pathogenesis of the Clostridia special issue

Regulation of toxin production in the pathogenic clostridia.

Reply to: Caution is warranted in using cephamycin antibiotics against recurrent Clostridioides difficile infection

Small animal models for the study of Clostridium difficile disease pathogenesis.

Solution structure and DNA binding of the catalytic domain of the large serine resolvase TnpX.

Spo0A differentially regulates toxin production in evolutionarily diverse strains of Clostridium difficile

Structural Characterization of Clostridium sordellii Spores of Diverse Human, Animal, and Environmental Origin and Comparison to Clostridium difficile Spores.

Synthesis and antimicrobial activity of binaphthyl-based, functionalized oxazole and thiazole peptidomimetics

TcdB or not TcdB: a tale of two Clostridium difficile toxins.

TcpM: a novel relaxase that mediates transfer of large conjugative plasmids from Clostridium perfringens

TcsL is an essential virulence factor in Clostridium sordellii ATCC 9714

The Clostridium perfringens Tet P determinant comprises two overlapping genes: tetA(P), which mediates active tetracycline efflux, and tetB(P), which is related to the ribosomal protection family of tetracycline-resistance determinants.

The NanI and NanJ sialidases of Clostridium perfringens are not essential for virulence

The Sialidase NanS Enhances Non-TcsL Mediated Cytotoxicity of Clostridium sordellii