Lista de obras - Seth L Masters - Dominio Público Uruguay

A Mutation Outside the Dimerization Domain Causing Atypical STING-Associated Vasculopathy With Onset in Infancy

scientific article published on 06 July 2018

A Toxoplasma gondii Gluconeogenic Enzyme Contributes to Robust Central Carbon Metabolism and Is Essential for Replication and Virulence

scientific article published on 01 August 2015

A healthy appetite for Toxoplasma at the cellular level.

artículo científico publicado en 2014

A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction

artículo científico publicado en 2020

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.

artículo científico publicado en 2015

ATF3 Is a Key Regulator of Macrophage IFN Responses

artículo científico

Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.

artículo científico publicado en 2015

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

artículo científico publicado en 2010

Activation of the NLRP3 inflammasome complex is not required for stress-induced death of pancreatic islets

artículo científico publicado en 2014

Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity

artículo científico publicado en 2014

An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell

artículo científico publicado en 2015

An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist

artículo científico publicado en 2009

Broadening the definition of autoinflammation

artículo científico publicado en 2015

Caspase substrates won't be defined by a four-letter code.

artículo científico publicado en 2018

Constitutive immune mechanisms: mediators of host defence and immune regulation

artículo científico publicado en 2020

Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1β production

artículo científico publicado en 2012

Deficiency in coatomer complex I causes aberrant activation of STING signalling

artículo científico publicado en 2022

Deficiency of 5-hydroxyisourate hydrolase causes hepatomegaly and hepatocellular carcinoma in mice

artículo científico publicado en 2010

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice

artículo científico publicado en 2015

Disease-associated amyloid and misfolded protein aggregates activate the inflammasome

artículo científico publicado en 2011

Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii

artículo científico publicado en 2014

Dynamics of the SPRY domain-containing SOCS box protein 2: flexibility of key functional loops

artículo científico publicado en 2006

Erratum: The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells

article

Faculty of 1000 evaluation for Activated STING in a vascular and pulmonary syndrome

Faculty of 1000 evaluation for Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling

Familial Mediterranean fever with a single MEFV mutation: where is the second hit?

artículo científico publicado en 2009

Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation. ⬇️

artículo científico publicado en 2016

Fas regulates neutrophil lifespan during viral and bacterial infection

artículo científico publicado en 2014

Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)

artículo científico publicado en 2009

Human DPP9 represses NLRP1 inflammasome and protects against auto-inflammatory diseases via both peptidase activity and FIIND domain binding

artículo científico publicado en 2018

IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome.

artículo científico publicado en 2015

Inhibition of interleukin-1β signalling promotes atherosclerotic lesion remodelling in mice with inflammatory arthritis

artículo científico publicado en 2020

Innate immunity

artículo científico publicado en 2014

Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling

artículo científico publicado en 2018

Letter to the Editor: Backbone 1H, 13C and 15N assignments of the 25 kDa SPRY domain-containing SOCS box protein 2 (SSB-2)

artículo científico publicado en 2005

Monogenic autoinflammatory diseases: Cytokinopathies

artículo científico

Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease

scientific article published on 11 December 2019

Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome.

artículo científico publicado en 2017

NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells

artículo científico publicado en 2012

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease

artículo científico publicado en 2018

NLRP1a expression in Srebp-1a-deficient mice

artículo científico publicado en 2014

NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5.

artículo científico publicado en 2015

Plasmacytoid dendritic cells are short-lived: reappraising the influence of migration, genetic factors and activation on estimation of lifespan

artículo científico publicado en 2016

Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition.

artículo científico publicado en 2017

Pyrin Modulates the Intracellular Distribution of PSTPIP1.

artículo científico publicado en 2009

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis

artículo científico publicado en 2014

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

artículo científico publicado en 2015

Recent advances in the molecular pathogenesis of hereditary recurrent fevers

artículo científico publicado en 2006

Regulation of Starch Stores by a Ca(2+)-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii

artículo científico publicado en 2015

Regulation of interleukin-1beta by interferon-gamma is species specific, limited by suppressor of cytokine signalling 1 and influences interleukin-17 production

artículo científico publicado en 2010

Release of the mitochondrial endosymbiont helps explain sterile inflammation

artículo científico publicado en 2010

SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm

artículo científico publicado en 2019

SPRY domain-containing SOCS box protein 2: crystal structure and residues critical for protein binding

artículo científico publicado en 2009

STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus

artículo científico publicado en 2007

Specific inflammasomes in complex diseases

artículo científico publicado en 2012

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

artículo científico publicado en 2013

TLR regulation of SPSB1 controls inducible nitric oxide synthase induction.

artículo científico publicado en 2011

The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production

artículo científico publicado en 2006

The Inflammasome in Atherosclerosis and Type 2 Diabetes

scientific article published on 01 May 2011

The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues

artículo científico publicado en 2005

The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation

artículo científico publicado en 2010

The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragment

artículo científico publicado en 2008

The molybdate binding protein Mop from Haemophilus influenzae—Biochemical and thermodynamic characterisation

scientific article published on 01 July 2005

The pathogen Candida albicans hijacks pyroptosis for escape from macrophages

artículo científico publicado en 2014

The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells.

artículo científico publicado en 2015

Transcriptional analysis of the three Nlrp1 paralogs in mice

artículo científico publicado en 2013

Ximmer: A system for improving accuracy and consistency of CNV calling from exome data

article by Simon P Sadedin et al published 6 September 2018 in GigaScience

miR‐223: infection, inflammation and cancer ⬇️

artículo científico publicado el 25 de junio de 2013

Lista de obras de Seth L Masters

A Mutation Outside the Dimerization Domain Causing Atypical STING-Associated Vasculopathy With Onset in Infancy

A Toxoplasma gondii Gluconeogenic Enzyme Contributes to Robust Central Carbon Metabolism and Is Essential for Replication and Virulence

A healthy appetite for Toxoplasma at the cellular level.

A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.

ATF3 Is a Key Regulator of Macrophage IFN Responses

Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β.

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

Activation of the NLRP3 inflammasome complex is not required for stress-induced death of pancreatic islets

Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity

An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell

An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist

Broadening the definition of autoinflammation

Caspase substrates won't be defined by a four-letter code.

Constitutive immune mechanisms: mediators of host defence and immune regulation

Cutting edge: miR-223 and EBV miR-BART15 regulate the NLRP3 inflammasome and IL-1β production

Deficiency in coatomer complex I causes aberrant activation of STING signalling

Deficiency of 5-hydroxyisourate hydrolase causes hepatomegaly and hepatocellular carcinoma in mice

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice

Disease-associated amyloid and misfolded protein aggregates activate the inflammasome

Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii

Dynamics of the SPRY domain-containing SOCS box protein 2: flexibility of key functional loops

Erratum: The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells

Faculty of 1000 evaluation for Activated STING in a vascular and pulmonary syndrome

Faculty of 1000 evaluation for Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling

Familial Mediterranean fever with a single MEFV mutation: where is the second hit?

Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation. ⬇️

Fas regulates neutrophil lifespan during viral and bacterial infection

Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease (*)

Human DPP9 represses NLRP1 inflammasome and protects against auto-inflammatory diseases via both peptidase activity and FIIND domain binding

IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome.

Inhibition of interleukin-1β signalling promotes atherosclerotic lesion remodelling in mice with inflammatory arthritis

Innate immunity

Interleukin-1 receptor-associated kinase 4 (IRAK4) plays a dual role in myddosome formation and Toll-like receptor signaling

Letter to the Editor: Backbone 1H, 13C and 15N assignments of the 25 kDa SPRY domain-containing SOCS box protein 2 (SSB-2)

Monogenic autoinflammatory diseases: Cytokinopathies

Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease

Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome.

NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease

NLRP1a expression in Srebp-1a-deficient mice

NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5.

Plasmacytoid dendritic cells are short-lived: reappraising the influence of migration, genetic factors and activation on estimation of lifespan

Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition.

Pyrin Modulates the Intracellular Distribution of PSTPIP1.

RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis

RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL

Recent advances in the molecular pathogenesis of hereditary recurrent fevers

Regulation of Starch Stores by a Ca(2+)-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii

Regulation of interleukin-1beta by interferon-gamma is species specific, limited by suppressor of cytokine signalling 1 and influences interleukin-17 production

Release of the mitochondrial endosymbiont helps explain sterile inflammation

SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm

SPRY domain-containing SOCS box protein 2: crystal structure and residues critical for protein binding

STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus

Specific inflammasomes in complex diseases

Succinate is an inflammatory signal that induces IL-1β through HIF-1α.

TLR regulation of SPSB1 controls inducible nitric oxide synthase induction.

The B30.2 domain of pyrin, the familial Mediterranean fever protein, interacts directly with caspase-1 to modulate IL-1beta production

The Inflammasome in Atherosclerosis and Type 2 Diabetes

The SPRY domain of SSB-2 adopts a novel fold that presents conserved Par-4-binding residues

The SPRY domain-containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation

The familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragment

The molybdate binding protein Mop from Haemophilus influenzae—Biochemical and thermodynamic characterisation

The pathogen Candida albicans hijacks pyroptosis for escape from macrophages

The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells.

Transcriptional analysis of the three Nlrp1 paralogs in mice

Ximmer: A system for improving accuracy and consistency of CNV calling from exome data

miR‐223: infection, inflammation and cancer ⬇️