Lista de obras - Tune H Pers - Dominio Público Uruguay

52 Genetic Loci Influencing Myocardial Mass

artículo científico publicado en 2016

A Comprehensive Reanalysis Of Publicly Available GWAS Datasets Reveals An X Chromosome Rare Regulatory Variant Associated With High Risk For Type 2 Diabetes

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

artículo científico publicado en 2017

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

A distinct adipose tissue gene expression response to caloric restriction predicts 6-mo weight maintenance in obese subjects

artículo científico publicado en 2011

A genetic map of the mouse dorsal vagal complex and its role in obesity

artículo científico publicado en 2021

A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation

artículo científico publicado en 2011

A molecular census of arcuate hypothalamus and median eminence cell types

artículo científico publicado en 2017

A novel common variant in DCST2 is associated with length in early life and height in adulthood

artículo científico publicado en 2014

A single-cell atlas of human and mouse white adipose tissue

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

artículo científico publicado en 2017

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

artículo científico publicado en 2014

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

artículo científico publicado en 2016

Author Correction: Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis

artículo científico publicado en 2020

Benchmarker: An Unbiased, Association-Data-Driven Strategy to Evaluate Gene Prioritization Algorithms

article

Benchmarker: an unbiased, association-data-driven strategy to evaluate gene prioritization algorithms

article

Biological insights from 108 schizophrenia-associated genetic loci

artículo científico publicado en 2014

Biological interpretation of genome-wide association studies using predicted gene functions

artículo científico publicado en 2015

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

artículo científico publicado en 2014

Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes

artículo científico publicado en 2016

Concordance of gene expression in human protein complexes reveals tissue specificity and pathology

artículo científico publicado en 2013

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

artículo científico publicado en 2016

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2016

Decoding the porcine developing spatial processing system and production of human entorhinal stellate cell-like cells by a direct programming approach

artículo científico publicado en 2019

Defining the role of common variation in the genomic and biological architecture of adult human height

artículo científico publicado en 2014

Erratum: Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

artículo científico publicado en 2016

Fatness-associated FTO gene variant increases mortality independent of fatness--in cohorts of Danish men

artículo científico publicado en 2009

Gene expression analysis identifies global gene dosage sensitivity in cancer.

artículo científico publicado en 2015

Gene set analysis for interpreting genetic studies

artículo científico publicado en 2016

Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity

artículo científico publicado en 2015

Genetic analysis of dietary intake identifies new loci and functional links with metabolic traits

artículo científico publicado en 2021

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

artículo científico publicado en 2016

Genetic mapping of etiologic brain cell types for obesity

scientific article published on 21 September 2020

Genetic studies of body mass index yield new insights for obesity biology

artículo científico publicado en 2015

Genetic variants linked to education predict longevity

artículo científico publicado en 2016

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

artículo científico publicado en 2018

Genome-wide Analysis of Body Proportion Classifies Height-Associated Variants by Mechanism of Action and Implicates Genes Important for Skeletal Development

artículo científico publicado en 2015

Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

artículo científico publicado en 2016

Genome-wide association analyses identify variants in developmental genes associated with hypospadias

artículo científico publicado en 2014

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention ⬇️

artículo científico publicado en 2022

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

artículo científico publicado en 2015

Genome-wide association study identifies 30 loci associated with bipolar disorder.

artículo científico publicado en 2019

Genome-wide association study identifies 74 loci associated with educational attainment

artículo científico publicado en 2016

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

artículo científico publicado en 2016

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Human skeletal muscle CD90<sup>+</sup> fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

artículo científico publicado en 2021

Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis

artículo científico publicado en 2021

Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis

artículo científico publicado en 2020

Integrative annotation of variants from 1092 humans: application to cancer genomics

artículo científico publicado en 2013

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

artículo científico publicado en 2017

Macrophages and adipocytes in human obesity: adipose tissue gene expression and insulin sensitivity during calorie restriction and weight stabilization

artículo científico publicado en 2009

Mendelian Randomization Study of Body Mass Index and Colorectal Cancer Risk

artículo científico publicado en 2015

Mendelian randomization study of height and risk of colorectal cancer

artículo científico publicado en 2015

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

artículo científico publicado en 2016

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization

artículo científico publicado en 2013

Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes

artículo científico publicado en 2011

MetaRanker 2.0: a web server for prioritization of genetic variation data

artículo científico publicado en 2013

Metabolic network topology reveals transcriptional regulatory signatures of type 2 diabetes

artículo científico publicado en 2010

Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis

scientific article published on 24 January 2020

Multilocus heterozygosity and coronary heart disease: nested case-control studies in men and women

artículo científico publicado en 2015

Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism

artículo científico publicado en 2013

New genetic loci link adipose and insulin biology to body fat distribution

artículo científico publicado en 2015

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

artículo científico publicado en 2016

Novel microcephalic primordial dwarfism disorder associated with variants in the centrosomal protein ninein

artículo científico publicado en 2012

PAIRUP-MS: Pathway analysis and imputation to relate unknowns in profiles from mass spectrometry-based metabolite data

artículo científico publicado en 2019

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

article

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

artículo científico publicado en 2014

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

artículo científico publicado en 2014

Population genetic differentiation of height and body mass index across Europe

artículo científico publicado en 2015

Predicting facial characteristics from complex polygenic variations

artículo científico publicado en 2015

Protein interaction-based genome-wide analysis of incident coronary heart disease

artículo científico publicado en 2011

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2017

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

artículo científico publicado en 2019

Publisher Correction: Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.

artículo científico publicado en 2018

Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking

artículo científico publicado en 2019

Rare and low-frequency coding variants alter human adult height

artículo científico publicado en 2017

Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes

artículo científico publicado en 2018

RhoA in tyrosine hydroxylase neurones regulates food intake and body weight via altered sensitivity to peripheral hormones

scientific article published on 01 July 2019

SNPsnap: a Web-based tool for identification and annotation of matched SNPs

artículo científico publicado en 2014

Schizophrenia risk from complex variation of complement component 4

artículo científico publicado en 2016

Shared genetic variants suggest common pathways in allergy and autoimmune diseases

artículo científico publicado en 2017

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

artículo científico publicado en 2015

The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility

scholarly article published 13 July 2017

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

artículo científico publicado en 2016

The impact of low-frequency and rare variants on lipid levels

artículo científico publicado en 2015

The validation and assessment of machine learning: a game of prediction from high-dimensional data

artículo científico publicado en 2009

Tracing the origin of adult intestinal stem cells

scientific article published on 15 May 2019

Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission

artículo científico publicado en 2020

Twenty-eight genetic loci associated with ST-T-wave amplitudes of the electrocardiogram

artículo científico publicado en 2016

Whole-Exome Sequencing of 2,000 Danish Individuals and the Role of Rare Coding Variants in Type 2 Diabetes

Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes

artículo científico publicado en 2013

Lista de obras de Tune H Pers

52 Genetic Loci Influencing Myocardial Mass

A Comprehensive Reanalysis Of Publicly Available GWAS Datasets Reveals An X Chromosome Rare Regulatory Variant Associated With High Risk For Type 2 Diabetes

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

A distinct adipose tissue gene expression response to caloric restriction predicts 6-mo weight maintenance in obese subjects

A genetic map of the mouse dorsal vagal complex and its role in obesity

A genome-wide association study of men with symptoms of testicular dysgenesis syndrome and its network biology interpretation

A molecular census of arcuate hypothalamus and median eminence cell types

A novel common variant in DCST2 is associated with length in early life and height in adulthood

A single-cell atlas of human and mouse white adipose tissue

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

Author Correction: Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis

Benchmarker: An Unbiased, Association-Data-Driven Strategy to Evaluate Gene Prioritization Algorithms

Benchmarker: an unbiased, association-data-driven strategy to evaluate gene prioritization algorithms

Biological insights from 108 schizophrenia-associated genetic loci

Biological interpretation of genome-wide association studies using predicted gene functions

Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes

Concordance of gene expression in human protein complexes reveals tissue specificity and pathology

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Decoding the porcine developing spatial processing system and production of human entorhinal stellate cell-like cells by a direct programming approach

Defining the role of common variation in the genomic and biological architecture of adult human height

Erratum: Corrigendum: Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

Fatness-associated FTO gene variant increases mortality independent of fatness--in cohorts of Danish men

Gene expression analysis identifies global gene dosage sensitivity in cancer.

Gene set analysis for interpreting genetic studies

Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity

Genetic analysis of dietary intake identifies new loci and functional links with metabolic traits

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Genetic mapping of etiologic brain cell types for obesity

Genetic studies of body mass index yield new insights for obesity biology

Genetic variants linked to education predict longevity

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

Genome-wide Analysis of Body Proportion Classifies Height-Associated Variants by Mechanism of Action and Implicates Genes Important for Skeletal Development

Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis

Genome-wide association analyses identify variants in developmental genes associated with hypospadias

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention ⬇️

Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index

Genome-wide association study identifies 30 loci associated with bipolar disorder.

Genome-wide association study identifies 74 loci associated with educational attainment

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Human skeletal muscle CD90<sup>+</sup> fibro-adipogenic progenitors are associated with muscle degeneration in type 2 diabetic patients

Hypothalamic hormone-sensitive lipase regulates appetite and energy homeostasis

Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis

Integrative annotation of variants from 1092 humans: application to cancer genomics

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

Macrophages and adipocytes in human obesity: adipose tissue gene expression and insulin sensitivity during calorie restriction and weight stabilization

Mendelian Randomization Study of Body Mass Index and Colorectal Cancer Risk

Mendelian randomization study of height and risk of colorectal cancer

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization

Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes

MetaRanker 2.0: a web server for prioritization of genetic variation data

Metabolic network topology reveals transcriptional regulatory signatures of type 2 diabetes

Multi-omics characterization of a diet-induced obese model of non-alcoholic steatohepatitis

Multilocus heterozygosity and coronary heart disease: nested case-control studies in men and women

Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism

New genetic loci link adipose and insulin biology to body fat distribution

New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk ⬇️

Novel microcephalic primordial dwarfism disorder associated with variants in the centrosomal protein ninein

PAIRUP-MS: Pathway analysis and imputation to relate unknowns in profiles from mass spectrometry-based metabolite data

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

Population genetic differentiation of height and body mass index across Europe

Predicting facial characteristics from complex polygenic variations

Protein interaction-based genome-wide analysis of incident coronary heart disease

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Publisher Correction: Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.

Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking