Lista de obras - Enric Domingo - Dominio Público Uruguay

'Toxgnostics': an unmet need in cancer medicine

A candidate gene study of capecitabine-related toxicity in colorectal cancer identifies new toxicity variants at DPYD and a putative role for ENOSF1 rather than TYMS

artículo científico publicado en 2015

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

article

A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk

article

A study of genomic instability in early preneoplastic colonic lesions ⬇️

artículo científico publicado el 17 de diciembre de 2012

Acute absolute vasodilatation is associated with a lower vascular wall stiffness in pulmonary arterial hypertension

artículo científico publicado en 2011

Adjuvant capecitabine plus bevacizumab versus capecitabine alone in patients with colorectal cancer (QUASAR 2): an open-label, randomised phase 3 trial

artículo científico publicado en 2016

Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance

artículo científico publicado en 2014

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance

scientific article published on 19 February 2019

BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer

artículo científico publicado en 2017

Clonality Assessment and Clonal Ordering of Individual Neoplastic Crypts Shows Polyclonality of Colorectal Adenomas

artículo científico publicado en 2010

Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk

artículo científico publicado en 2007

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

artículo científico publicado en 2012

DNA polymerase ε and δ exonuclease domain mutations in endometrial cancer

artículo científico publicado en 2013

Evaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancer

artículo científico publicado en 2013

Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis

artículo científico publicado en 2014

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas ⬇️

artículo científico publicado en 2013

Guidelines for using sigQC for systematic evaluation of gene signatures

artículo científico publicado en 2019

Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning

artículo científico publicado en 2020

Impairment of pulmonary vascular reserve and right ventricular systolic reserve in pulmonary arterial hypertension

artículo científico publicado en 2014

In-depth clinical and biological exploration of DNA Damage Immune Response (DDIR) as a biomarker for oxaliplatin use in colorectal cancer

artículo científico publicado en 2020

Is sidedness prognostically important across all stages of colorectal cancer?

scientific article published on 01 November 2016

KRAS Mutation Is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer

artículo científico publicado en 2011

KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression

article

Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

artículo científico publicado en 2008

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

artículo científico publicado en 2010

New concepts in the invasive and non invasive evaluation of remodelling of the right ventricle and pulmonary vasculature in pulmonary arterial hypertension.

artículo científico publicado en 2009

Pharmacoproteomic characterisation of human colon and rectal cancer.

artículo científico publicado en 2017

Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer

article

Replication stress links structural and numerical cancer chromosomal instability

artículo científico publicado en 2013

Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution.

artículo científico publicado en 2017

Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study

artículo científico publicado en 2016

Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations

artículo científico publicado en 2013

TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts

artículo científico publicado en 2020

The evolutionary landscape of colorectal tumorigenesis ⬇️

scientific article published on 31 August 2018

The interleukin 22 pathway interacts with mutant KRAS to promote poor prognosis in colon cancer

artículo científico publicado en 2020

The proportion of tumor-stroma as a strong prognosticator for stage II and III colon cancer patients: validation in the VICTOR trial

scientific article published on 02 August 2012

Use of multivariate analysis to suggest a new molecular classification of colorectal cancer.

artículo científico publicado en 2013

Lista de obras de Enric Domingo

'Toxgnostics': an unmet need in cancer medicine

A candidate gene study of capecitabine-related toxicity in colorectal cancer identifies new toxicity variants at DPYD and a putative role for ENOSF1 rather than TYMS

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk

A study of genomic instability in early preneoplastic colonic lesions ⬇️

Acute absolute vasodilatation is associated with a lower vascular wall stiffness in pulmonary arterial hypertension

Adjuvant capecitabine plus bevacizumab versus capecitabine alone in patients with colorectal cancer (QUASAR 2): an open-label, randomised phase 3 trial

Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance

BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer

Clonality Assessment and Clonal Ordering of Individual Neoplastic Crypts Shows Polyclonality of Colorectal Adenomas

Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk

Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

DNA polymerase ε and δ exonuclease domain mutations in endometrial cancer

Evaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancer

Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas ⬇️

Guidelines for using sigQC for systematic evaluation of gene signatures

Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning

Impairment of pulmonary vascular reserve and right ventricular systolic reserve in pulmonary arterial hypertension

In-depth clinical and biological exploration of DNA Damage Immune Response (DDIR) as a biomarker for oxaliplatin use in colorectal cancer

Is sidedness prognostically important across all stages of colorectal cancer?

KRAS Mutation Is Associated with Lung Metastasis in Patients with Curatively Resected Colorectal Cancer

KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression

Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

New concepts in the invasive and non invasive evaluation of remodelling of the right ventricle and pulmonary vasculature in pulmonary arterial hypertension.

Pharmacoproteomic characterisation of human colon and rectal cancer.

Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer

Replication stress links structural and numerical cancer chromosomal instability

Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution.

Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study

Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations

TEX264 coordinates p97- and SPRTN-mediated resolution of topoisomerase 1-DNA adducts

The evolutionary landscape of colorectal tumorigenesis ⬇️

The interleukin 22 pathway interacts with mutant KRAS to promote poor prognosis in colon cancer

The proportion of tumor-stroma as a strong prognosticator for stage II and III colon cancer patients: validation in the VICTOR trial

Use of multivariate analysis to suggest a new molecular classification of colorectal cancer.