Lista de obras - Martin J McPhillie - Dominio Público Uruguay

Activity of and development of resistance to corallopyronin A, an inhibitor of RNA polymerase

artículo científico publicado en 2011

An in silico structure-based approach to anti-infective drug discovery

artículo científico

Applications of structure-based design to antibacterial drug discovery

artículo científico

CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii ⬇️

artículo científico publicado en 2018

Computational methods to identify new antibacterial targets

artículo científico publicado en 2015

Development of a triclosan scaffold which allows for adaptations on both the A- and B-ring for transport peptides

artículo científico publicado en 2013

Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay

artículo científico publicado en 2013

Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM. ⬇️

artículo científico publicado en 2018

Identification of a small molecule inhibitor of Ebola virus genome replication and transcription using in silico screening ⬇️

artículo científico publicado en 2018

N-Cinnamoylanthranilates as human TRPA1 modulators: Structure-activity relationships and channel binding sites

scientific article published on 04 March 2019

New Opportunities in the Structure-based Design of Anti-Protozoan Agents ⬇️

artículo científico publicado en 2016

New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections ⬇️

artículo científico publicado en 2016

Structure-based ligand design of novel bacterial RNA polymerase inhibitors

artículo científico publicado en 2011

The Growing Role of Electron Microscopy in Anti-parasitic Drug Discovery ⬇️

artículo científico publicado en 2017

The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target

artículo científico publicado en 2014

The potential use of single-particle electron microscopy as a tool for structure-based inhibitor design. ⬇️

artículo científico publicado en 2017

Lista de obras de Martin J McPhillie

Activity of and development of resistance to corallopyronin A, an inhibitor of RNA polymerase

An in silico structure-based approach to anti-infective drug discovery

Applications of structure-based design to antibacterial drug discovery

CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii ⬇️

Computational methods to identify new antibacterial targets

Development of a triclosan scaffold which allows for adaptations on both the A- and B-ring for transport peptides

Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay

Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM. ⬇️

Identification of a small molecule inhibitor of Ebola virus genome replication and transcription using in silico screening ⬇️

N-Cinnamoylanthranilates as human TRPA1 modulators: Structure-activity relationships and channel binding sites

New Opportunities in the Structure-based Design of Anti-Protozoan Agents ⬇️

New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections ⬇️

Structure-based ligand design of novel bacterial RNA polymerase inhibitors

The Growing Role of Electron Microscopy in Anti-parasitic Drug Discovery ⬇️

The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target

The potential use of single-particle electron microscopy as a tool for structure-based inhibitor design. ⬇️