Lista de obras - Toby Lawrence - Dominio Público Uruguay

An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation.

artículo científico publicado en 2014

Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1.

artículo científico publicado en 2006

Autophagy in dendritic cells.

artículo científico publicado en 2018

Bone marrow-specific knock-in of a non-activatable Ikkα kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice

scientific article published on 03 February 2014

CANCER: Sex, Cytokines, and Cancer

artículo científico publicado en 2007

Chronic inflammation: a failure of resolution?

artículo científico publicado en 2007

Cigarette smoke induced airway inflammation is independent of NF-κB signalling

artículo científico publicado en 2013

Coordinated Regulation of Signaling Pathways during Macrophage Activation

artículo científico publicado en 2016

Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programming

artículo científico publicado en 2014

GADD45β loss ablates innate immunosuppression in cancer ⬇️

artículo científico publicado en 2017

Hematopoietic prostaglandin D2 synthase controls the onset and resolution of acute inflammation through PGD2 and 15-deoxyDelta12 14 PGJ2.

artículo científico publicado en 2007

High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling

artículo científico publicado en 2016

Homeostatic NF-κB Signaling in Steady-State Migratory Dendritic Cells Regulates Immune Homeostasis and Tolerance.

artículo científico publicado en 2015

I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection

artículo científico publicado en 2013

IKKalpha in the regulation of inflammation and adaptive immunity.

artículo científico publicado en 2007

Inflammation and cancer: a double-edged sword.

artículo científico publicado en 2007

Inflammation and cancer: a failure of resolution?

artículo científico publicado en 2007

Inhibition of the tumor necrosis factor-alpha pathway is radioprotective for the lung

artículo científico publicado en 2008

Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer

artículo científico publicado en 2006

Investigating macrophage and malignant cell interactions in vitro

artículo científico publicado en 2009

Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes

artículo científico publicado en 2016

Macrophage activation and polarization: nomenclature and experimental guidelines

artículo científico publicado en 2014

Macrophages and NF-κB in cancer.

scientific article published on January 2011

Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression

scientific article published on 28 March 2019

Molecular dissection of plasmacytoid dendritic cell activation during a viral infection

scientific article published on 21 August 2018

Novel biphasic role for lymphocytes revealed during resolving inflammation

artículo científico publicado en 2008

Platelet CD40L Modulates Thrombus Growth Via Phosphatidylinositol 3-Kinase β, and Not Via CD40 and IκB Kinase α.

artículo científico publicado en 2015

Precise and Rapid Validation of Candidate Gene by Allele Specific Knockout With CRISPR/Cas9 in Wild Mice

article

Receptor Activator of NF-κB Orchestrates Activation of Antiviral Memory CD8 T Cells in the Spleen Marginal Zone.

artículo científico publicado en 2017

Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways

artículo científico publicado en 2018

Soluble ectodomain CD163 and extracellular vesicle-associated CD163 are two differently regulated forms of 'soluble CD163' in plasma

artículo científico publicado en 2017

Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression

artículo científico publicado en 2019

TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine.

artículo científico publicado en 2017

Targeting STAT3 and STAT5 in Tumor-Associated Immune Cells to Improve Immunotherapy

scientific article published on 21 November 2019

The nuclear factor NF-kappaB pathway in inflammation

artículo científico publicado en 2009

The pore-forming toxin β hemolysin/cytolysin triggers p38 MAPK-dependent IL-10 production in macrophages and inhibits innate immunity

artículo científico publicado en 2012

The three members of the Vav family proteins form complexes that concur to foam cell formation and atherosclerosis

artículo científico publicado en 2019

The tumor-promoting actions of TNF-alpha involve TNFR1 and IL-17 in ovarian cancer in mice and humans

artículo científico publicado en 2009

The ubiquitin ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation.

artículo científico publicado en 2017

Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer

artículo científico publicado en 2020

Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles

artículo científico publicado en 2017

Lista de obras de Toby Lawrence

An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation.

Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1.

Autophagy in dendritic cells.

Bone marrow-specific knock-in of a non-activatable Ikkα kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice

CANCER: Sex, Cytokines, and Cancer

Chronic inflammation: a failure of resolution?

Cigarette smoke induced airway inflammation is independent of NF-κB signalling

Coordinated Regulation of Signaling Pathways during Macrophage Activation

Dendritic cell maturation: functional specialization through signaling specificity and transcriptional programming

GADD45β loss ablates innate immunosuppression in cancer ⬇️

Hematopoietic prostaglandin D2 synthase controls the onset and resolution of acute inflammation through PGD2 and 15-deoxyDelta12 14 PGJ2.

High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling

Homeostatic NF-κB Signaling in Steady-State Migratory Dendritic Cells Regulates Immune Homeostasis and Tolerance.

I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infection

IKKalpha in the regulation of inflammation and adaptive immunity.

Inflammation and cancer: a double-edged sword.

Inflammation and cancer: a failure of resolution?

Inhibition of the tumor necrosis factor-alpha pathway is radioprotective for the lung

Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer

Investigating macrophage and malignant cell interactions in vitro

Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes

Macrophage activation and polarization: nomenclature and experimental guidelines

Macrophages and NF-κB in cancer.

Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression

Molecular dissection of plasmacytoid dendritic cell activation during a viral infection

Novel biphasic role for lymphocytes revealed during resolving inflammation

Platelet CD40L Modulates Thrombus Growth Via Phosphatidylinositol 3-Kinase β, and Not Via CD40 and IκB Kinase α.

Precise and Rapid Validation of Candidate Gene by Allele Specific Knockout With CRISPR/Cas9 in Wild Mice

Receptor Activator of NF-κB Orchestrates Activation of Antiviral Memory CD8 T Cells in the Spleen Marginal Zone.

Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways

Soluble ectodomain CD163 and extracellular vesicle-associated CD163 are two differently regulated forms of 'soluble CD163' in plasma

Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression

TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine.

Targeting STAT3 and STAT5 in Tumor-Associated Immune Cells to Improve Immunotherapy

The nuclear factor NF-kappaB pathway in inflammation

The pore-forming toxin β hemolysin/cytolysin triggers p38 MAPK-dependent IL-10 production in macrophages and inhibits innate immunity

The three members of the Vav family proteins form complexes that concur to foam cell formation and atherosclerosis

The tumor-promoting actions of TNF-alpha involve TNFR1 and IL-17 in ovarian cancer in mice and humans

The ubiquitin ligase ZNRF1 promotes caveolin-1 ubiquitination and degradation to modulate inflammation.

Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer

Tumor-associated macrophages (TAMs) depend on ZEB1 for their cancer-promoting roles