Lista de obras - Christopher P Wardell - Dominio Público Uruguay

A TC classification-based predictor for multiple myeloma using multiplexed real-time quantitative PCR.

artículo científico publicado en 2013

A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis

artículo científico publicado en 2019

A modified method for whole exome resequencing from minimal amounts of starting DNA

artículo científico publicado en 2012

A molecular diagnostic approach able to detect the recurrent genetic prognostic factors typical of presenting myeloma

artículo científico publicado en 2014

A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex

artículo científico publicado en 2014

A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial.

artículo científico publicado en 2011

APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma ⬇️

artículo científico publicado en 2015

Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma

artículo científico publicado en 2010

BRAF and DIS3 Mutations Associate with Adverse Outcome in a Long-term Follow-up of Patients with Multiple Myeloma

scientific article published on 27 January 2020

Cancer whole-genome sequencing: present and future.

artículo científico

Characterization of IGH locus breakpoints in multiple myeloma indicates a subset of translocations appear to occur in pregerminal center B cells.

artículo científico publicado en 2013

Cleavage of BLOC1S1 mRNA by IRE1 Is Sequence Specific, Temporally Separate from XBP1 Splicing, and Dispensable for Cell Viability under Acute Endoplasmic Reticulum Stress

artículo científico publicado en 2015

Coexistent hyperdiploidy does not abrogate poor prognosis in myeloma with adverse cytogenetics and may precede IGH translocations

artículo científico publicado en 2014

Daratumumab and dexamethasone is safe and effective for triple refractory myeloma patients: final results of the IFM 2014-04 (Etoile du Nord) trial

scientific article published on 19 June 2019

Erratum: Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer

artículo científico publicado en 2016

Gender disparities in the tumor genetics and clinical outcome of multiple myeloma

artículo científico publicado en 2011

Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by an ELL2 Enhancer Polymorphism

artículo científico publicado en 2017

Genomewide profiling of copy-number alteration in monoclonal gammopathy of undetermined significance

artículo científico publicado en 2016

Genomic Characterization of Biliary Tract Cancers Identifies Driver Genes and Predisposing Mutations.

artículo científico publicado en 2018

Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns

scientific article published on 19 June 2020

Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma.

artículo científico publicado en 2013

HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target.

artículo científico publicado en 2018

High expression levels of the mammalian target of rapamycin inhibitor DEPTOR are predictive of response to thalidomide in myeloma.

artículo científico publicado en 2010

Identification of a novel t(7;14) translocation in multiple myeloma resulting in overexpression of EGFR.

artículo científico publicado en 2013

Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma

scientific article published on 08 June 2018

Improved risk stratification in myeloma using a microRNA-based classifier.

artículo científico publicado en 2013

Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma.

artículo científico publicado en 2012

Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms

scientific article published on 02 July 2013

Mapping of chromosome 1p deletions in myeloma identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as being genes in regions associated with adverse survival.

artículo científico publicado en 2011

Microhomology-mediated end joining drives complex rearrangements and over expression of MYC and PVT1 in multiple myeloma: Supplementary Data

scientific article published on 10 January 2019

Mutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.

artículo científico publicado en 2015

Neutral tumor evolution in myeloma is associated with poor prognosis. ⬇️

artículo científico publicado en 2017

Proof of the concept to use a malignant B cell line drug screen strategy for identification and weight of melphalan resistance genes in multiple myeloma

artículo científico publicado en 2013

Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma

article

Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing

artículo científico publicado en 2017

TCF12 is mutated in anaplastic oligodendroglioma

artículo científico publicado en 2015

The Spectrum and Clinical Impact of Epigenetic Modifier Mutations in Myeloma. ⬇️

artículo científico publicado en 2016

The clinical impact and molecular biology of del(17p) in multiple myeloma treated with conventional or thalidomide-based therapy

artículo científico publicado en 2011

The genomic landscape of plasma cells in systemic light chain amyloidosis

scientific article published on 16 November 2018

The spectrum of somatic mutations in monoclonal gammopathy of undetermined significance indicates a less complex genomic landscape than that in multiple myeloma

artículo científico publicado en 2017

Translocations at 8q24 juxtapose MYC with genes that harbor superenhancers resulting in overexpression and poor prognosis in myeloma patients

artículo científico publicado en 2014

Whole genome sequencing discriminates hepatocellular carcinoma with intrahepatic metastasis from multi-centric tumors

artículo científico publicado en 2016

Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer.

artículo científico publicado en 2016

Lista de obras de Christopher P Wardell

A TC classification-based predictor for multiple myeloma using multiplexed real-time quantitative PCR.

A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis

A modified method for whole exome resequencing from minimal amounts of starting DNA

A molecular diagnostic approach able to detect the recurrent genetic prognostic factors typical of presenting myeloma

A novel functional role for MMSET in RNA processing based on the link between the REIIBP isoform and its interaction with the SMN complex

A novel prognostic model in myeloma based on co-segregating adverse FISH lesions and the ISS: analysis of patients treated in the MRC Myeloma IX trial.

APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma ⬇️

Aberrant global methylation patterns affect the molecular pathogenesis and prognosis of multiple myeloma

BRAF and DIS3 Mutations Associate with Adverse Outcome in a Long-term Follow-up of Patients with Multiple Myeloma

Cancer whole-genome sequencing: present and future.

Characterization of IGH locus breakpoints in multiple myeloma indicates a subset of translocations appear to occur in pregerminal center B cells.

Cleavage of BLOC1S1 mRNA by IRE1 Is Sequence Specific, Temporally Separate from XBP1 Splicing, and Dispensable for Cell Viability under Acute Endoplasmic Reticulum Stress

Coexistent hyperdiploidy does not abrogate poor prognosis in myeloma with adverse cytogenetics and may precede IGH translocations

Daratumumab and dexamethasone is safe and effective for triple refractory myeloma patients: final results of the IFM 2014-04 (Etoile du Nord) trial

Erratum: Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer

Gender disparities in the tumor genetics and clinical outcome of multiple myeloma

Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by an ELL2 Enhancer Polymorphism

Genomewide profiling of copy-number alteration in monoclonal gammopathy of undetermined significance

Genomic Characterization of Biliary Tract Cancers Identifies Driver Genes and Predisposing Mutations.

Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns

Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma.

HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target.

High expression levels of the mammalian target of rapamycin inhibitor DEPTOR are predictive of response to thalidomide in myeloma.

Identification of a novel t(7;14) translocation in multiple myeloma resulting in overexpression of EGFR.

Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma

Improved risk stratification in myeloma using a microRNA-based classifier.

Intraclonal heterogeneity and distinct molecular mechanisms characterize the development of t(4;14) and t(11;14) myeloma.

Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms

Mapping of chromosome 1p deletions in myeloma identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as being genes in regions associated with adverse survival.

Microhomology-mediated end joining drives complex rearrangements and over expression of MYC and PVT1 in multiple myeloma: Supplementary Data

Mutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma.

Neutral tumor evolution in myeloma is associated with poor prognosis. ⬇️

Proof of the concept to use a malignant B cell line drug screen strategy for identification and weight of melphalan resistance genes in multiple myeloma

Single-cell genetic analysis reveals the composition of initiating clones and phylogenetic patterns of branching and parallel evolution in myeloma

Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing

TCF12 is mutated in anaplastic oligodendroglioma

The Spectrum and Clinical Impact of Epigenetic Modifier Mutations in Myeloma. ⬇️

The clinical impact and molecular biology of del(17p) in multiple myeloma treated with conventional or thalidomide-based therapy

The genomic landscape of plasma cells in systemic light chain amyloidosis

The spectrum of somatic mutations in monoclonal gammopathy of undetermined significance indicates a less complex genomic landscape than that in multiple myeloma

Translocations at 8q24 juxtapose MYC with genes that harbor superenhancers resulting in overexpression and poor prognosis in myeloma patients

Whole genome sequencing discriminates hepatocellular carcinoma with intrahepatic metastasis from multi-centric tumors

Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer.