Lista de obras - Anthony D Whetton - Dominio Público Uruguay

5′-Nucleotidase is activated upon cholesterol-depletion of liver plasma membranes

artículo científico publicado en 1983

A combined biomarker panel shows improved sensitivity for the early detection of ovarian cancer allowing the identification of the most aggressive type II tumours.

artículo científico publicado en 2017

A comparison of the effect of bcr/abl breakpoint specific phosphothiorate oligodeoxynucleotides on colony formation by bcr/abl positive and negative, CD34 enriched mononuclear cell populations

artículo científico publicado en 1996

A gel-free quantitative proteomics analysis of factors released from hypoxic-conditioned placentae

artículo científico publicado en 2009

A hierarchical statistical modeling approach to analyze proteomic isobaric tag for relative and absolute quantitation data

artículo científico publicado en 2013

A label-free selected reaction monitoring workflow identifies a subset of pregnancy specific glycoproteins as potential predictive markers of early-onset pre-eclampsia

artículo científico publicado en 2013

A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response

artículo científico publicado en 2017

A novel mechanism for BCR-ABL action: stimulated secretion of CCN3 is involved in growth and differentiation regulation

artículo científico publicado en 2006

A pathway from leukemogenic oncogenes and stem cell chemokines to RNA processing via THOC5.

artículo científico publicado en 2012

A proof-of-principle gel-free proteomics strategy for the identification of predictive biomarkers for the onset of pre-eclampsia

artículo científico publicado en 2009

A proteomic analysis of murine bone marrow and its response to ionizing radiation.

artículo científico publicado en 2005

A sensitive mass spectrometric method for hypothesis-driven detection of peptide post-translational modifications: multiple reaction monitoring-initiated detection and sequencing (MIDAS).

artículo científico publicado en 2009

A specific PTPRC/CD45 phosphorylation event governed by stem cell chemokine CXCL12 regulates primitive hematopoietic cell motility

artículo científico publicado en 2013

AXL Inhibition Extinguishes Primitive JAK2 Mutated Myeloproliferative Neoplasm Progenitor Cells

artículo científico publicado en 2019

Acquired cross-linker resistance associated with a novel spliced BRCA2 protein variant for molecular phenotyping of BRCA2 disruption.

artículo científico publicado en 2017

Adenosine triphosphate can maintain multipotent haemopoietic stem cells in the absence of interleukin 3 via a membrane permeabilization mechanism

artículo científico publicado en 1988

Amplification and translocation of 3q26 with overexpression of EVI1 in Fanconi anemia-derived childhood acute myeloid leukemia with biallelic FANCD1/BRCA2 disruption

artículo científico publicado en 2007

An assessment of peptide enrichment methods employing mTRAQ quantification approaches

artículo científico publicado en 2012

An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5

artículo científico publicado en 2011

Antibody-based detection of protein phosphorylation status to track the efficacy of novel therapies using nanogram protein quantities from stem cells and cell lines.

artículo científico publicado en 2014

Apoptosis is regulated by the rate of glucose transport in an interleukin 3 dependent cell line

artículo científico publicado en 1994

Application of the MIDAS Approach for Analysis of Lysine Acetylation Sites

article

Application of two-dimensional difference gel electrophoresis to studying bone marrow macrophages and their in vivo responses to ionizing radiation.

artículo científico publicado en 2005

Assessment of downstream effectors of BCR/ABL protein tyrosine kinase using combined proteomic approaches

artículo científico publicado en 2010

BCR-ABL affects STAT5A and STAT5B differentially

artículo científico publicado en 2014

BCR/ABL modulates protein phosphorylation associated with the etoposide-induced DNA damage response

artículo científico publicado en 2012

Bcr-Abl-mediated molecular mechanism for apoptotic suppression in multipotent haemopoietic cells: a role for PKCbetaII.

artículo científico publicado en 2004

Candidate plasma biomarkers for predicting ascending aortic aneurysm in bicuspid aortic valve disease.

artículo científico publicado en 2018

Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation.

artículo científico publicado en 2005

Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P3) and lack a PtdIns(3,4,5)P3 response to cytokines and chemotactic factors; effects reversed by imatinib.

artículo científico publicado en 2005

Comparative proteomics of primitive hematopoietic cell populations reveals differences in expression of proteins regulating motility

scientific article published on 05 February 2004

Comparative quantification of the surfaceome of human multipotent mesenchymal progenitor cells.

artículo científico publicado en 2015

Cord Blood-Derived Quiescent CD34+ Cells Are More Transcriptionally Matched to AML Blasts Than Cytokine-Induced Normal Human Hematopoietic CD34+ Cells

artículo científico publicado en 2015

Data Independent Acquisition Mass Spectrometry Can Identify Circulating Proteins That Predict Future Weight Loss with a Diet and Exercise Programme

scientific article published on 25 January 2019

Development of Multipotential Haemopoietic Stem Cells to Neutrophils is Associated with Increased Expression of Receptors for Granulocyte Macrophage Colony-Stimulating Factor: Altered Biological Responses to GM-CSF during Development ⬇️

artículo científico publicado el 1 de enero de 1991

Development of a selected reaction monitoring mass spectrometry-based assay to detect asparaginyl endopeptidase activity in biological fluids

artículo científico publicado en 2016

Development of approaches for systematic analysis of protein networks in stem cells

article

Developmental fate determination and marker discovery in hematopoietic stem cell biology using proteomic fingerprinting

artículo científico publicado en 2007

Diagnosis of epithelial ovarian cancer using a combined protein biomarker panel

scientific article published on 07 August 2019

Differential effect of leukaemogenic tyrosine kinases on cell motility is governed by subcellular localisation.

artículo científico publicado en 2006

Dimethylnitrosamine inhibits the glucagon-stimulated adenylate cyclase activity of rat liver plasma membranes and decreases plasma membrane fluidity

artículo científico publicado en 1984

Discovery and Evaluation of Protein Biomarkers as a Signature of Wellness in Late-Stage Cancer Patients in Early Phase Clinical Trials

artículo científico publicado en 2021

Discovery and Validation of Predictive Biomarkers of Survival for Non-small Cell Lung Cancer Patients Undergoing Radical Radiotherapy: Two Proteins With Predictive Value

artículo científico publicado en 2015

Drosophila F-BAR protein Syndapin contributes to coupling the plasma membrane and contractile ring in cytokinesis

artículo científico publicado en 2013

Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells

artículo científico publicado en 2016

ERK and AKT phosphorylation status in lung cancer and emphysema using nanocapillary isoelectric focusing

artículo científico

EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association

artículo científico publicado en 2018

Effect of haematopoietic cell growth factor on intracellular ATP levels.

artículo científico publicado en 1983

Eight-channel iTRAQ enables comparison of the activity of six leukemogenic tyrosine kinases

artículo científico publicado en 2007

FMIP controls the adipocyte lineage commitment of C2C12 cells by downmodulation of C/EBP alpha.

artículo científico publicado en 2006

Fanconi anemia (FA)-associated 3q gains in leukemic transformation consistently target EVI1, but do not affect low TERC expression in FA

artículo científico publicado en 2011

Flt3 ligand can promote survival and macrophage development without proliferation in myeloid progenitor cells

article

Forskolin and ethanol both perturb the structure of liver plasma membranes and activate adenylate cyclase activity.

artículo científico publicado en 1983

Further characterisation of the in situ terminal deoxynucleotidyl transferase (TdT) assay for the flow cytometric analysis of apoptosis in drug resistant and drug sensitive leukaemic cells.

artículo científico publicado en 1995

Generation of a conditionally immortalized myeloid progenitor cell line requiring the presence of both interleukin-3 and stem cell factor to survive and proliferate

artículo científico publicado en 2003

Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemia

artículo científico publicado en 2011

Global effects of BCR/ABL and TEL/PDGFRbeta expression on the proteome and phosphoproteome: identification of the Rho pathway as a target of BCR/ABL.

artículo científico publicado en 2004

Glucocorticoid receptor isoforms direct distinct mitochondrial programs to regulate ATP production ⬇️

artículo científico publicado en 2016

Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy.

artículo científico publicado en 2015

Glucose transport regulation by p210 Bcr-Abl in a chronic myeloid leukaemia model.

artículo científico publicado en 2001

Guanidination chemistry for qualitative and quantitative proteomics

artículo científico publicado en 2006

Haemopoietic growth factors

Heterozygote FANCD2 mutations associated with childhood T Cell ALL and testicular seminoma

artículo científico publicado en 2012

Homing and mobilization in the stem cell niche.

artículo científico publicado en 1999

How will haematologists use proteomics?

artículo científico publicado en 2007

Hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival.

artículo científico publicado en 2018

Identification of a Biomarker Panel for Early Detection of Lung Cancer Patients

scientific article published on 21 August 2019

Identification of nuclear protein targets for six leukemogenic tyrosine kinases governed by post-translational regulation

artículo científico publicado en 2012

Identification of primary structural features that define the differential actions of IL-3 and GM-CSF receptors

artículo científico publicado en 2002

Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia

artículo científico publicado en 2019

Interleukin-3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface

artículo científico publicado en 2003

Is Serum or Plasma More Appropriate for Intersubject Comparisons in Metabolomic Studies? An Assessment in Patients with Small-Cell Lung Cancer

article

JAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34+ cells in vitro and in vivo.

artículo científico publicado en 2014

Liquid chromatography-mass spectrometry calibration transfer and metabolomics data fusion

artículo científico publicado en 2012

Lysophospholipids synergistically promote primitive hematopoietic cell chemotaxis via a mechanism involving Vav 1

artículo científico publicado en 2003

MPL W515L expression induces TGFβ secretion and leads to an increase in chemokinesis via phosphorylation of THOC5.

artículo científico publicado en 2016

Macrophage inflammatory protein-1 alpha mediated growth inhibition in a haemopoietic stem cell line is associated with inositol 1,4,5 triphosphate generation.

artículo científico publicado en 1995

Models to Study Chronic Myeloid Leukemia Cancer Stem Cells

Modern trends in human leukemia VI. Wilsede, June 17-21, 1984.

artículo científico publicado en 1985

Molecular histology of lung cancer: from targets to treatments

artículo científico

Monocyte-derived dendritic cells from chronic myeloid leukaemia have abnormal maturation and cytoskeletal function that is associated with defective localisation and signalling by normal ABL1 protein.

artículo científico publicado en 2014

Multiple Reaction Monitoring to Identify Sites of Protein Phosphorylation with High Sensitivity

article

Mutation of a phosphorylatable residue in Put3p affects the magnitude of rapamycin-induced PUT1 activation in a Gat1p-dependent manner

artículo científico publicado en 2009

Myeloid haemopoietic growth factors.

artículo científico

Neuropeptide control of bone marrow neutrophil production is mediated by both direct and indirect effects on CFU-GM

article

Novel risk models for early detection and screening of ovarian cancer

artículo científico publicado en 2016

Nuclear localization of the pre-mRNA associating protein THOC7 depends upon its direct interaction with Fms tyrosine kinase interacting protein (FMIP)

artículo científico publicado en 2009

Oncogenic MYC amplifies mitotic perturbations

scientific article published on 28 August 2019

PEDRo: a database for storing, searching and disseminating experimental proteomics data

artículo científico publicado en 2004

Perturbations of liver plasma membranes induced by Ca2+ are detected using a fatty acid spin label and adenylate cyclase as membrane probes.

artículo científico publicado en 1983

Phosphorylation of the leukemic oncoprotein EVI1 on serine 196 modulates DNA binding, transcriptional repression and transforming ability

artículo científico publicado en 2013

Protein Z: A putative novel biomarker for early detection of ovarian cancer

artículo científico publicado en 2016

Protein kinase C delta is phosphorylated on five novel Ser/Thr sites following inducible overexpression in human colorectal cancer cells

artículo científico publicado en 2007

Proteome Biology of Stem Cells

artículo científico publicado en 2008

Proteome biology of stem cells

Proteomic Analysis of an Induced Pluripotent Stem Cell Model Reveals Strategies to Treat Juvenile Myelomonocytic Leukemia

artículo científico publicado en 2019

Proteomic Biomarkers for the Detection of Endometrial Cancer

scientific article published on 16 October 2019

Proteomic analyses of intermediate filaments reveals cytokeratin8 is highly acetylated--implications for colorectal epithelial homeostasis

artículo científico publicado en 2008

Proteomic analysis of JAK2V617F-induced changes identifies potential new combinatorial therapeutic approaches

artículo científico publicado en 2017

Proteomic analysis of chronic lymphocytic leukemia subtypes with mutated or unmutated Ig V(H) genes

artículo científico publicado en 2003

Proteomics techniques and their application to hematology

artículo científico publicado en 2004

Quantitative mass spectrometry-based techniques for clinical use: biomarker identification and quantification

artículo científico publicado en 2008

Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition

artículo científico publicado en 2015

Quantitative proteomic analysis using isobaric protein tags enables rapid comparison of changes in transcript and protein levels in transformed cells

artículo científico publicado en 2005

Quantitative proteomics analysis demonstrates post-transcriptional regulation of embryonic stem cell differentiation to hematopoiesis

artículo científico publicado en 2007

Quantitative proteomics analysis of BMS-214662 effects on CD34 positive cells from chronic myeloid leukaemia patients.

artículo científico publicado en 2013

Quantitative proteomics reveals posttranslational control as a regulatory factor in primary hematopoietic stem cells

scientific article published on 28 February 2006

RAC2, AEP, and ICAM1 expression are associated with CNS disease in a mouse model of pre-B childhood acute lymphoblastic leukemia

artículo científico publicado en 2011

Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling

artículo científico publicado en 2012

Regulation of neutrophil and macrophage production by growth factors.

artículo científico publicado en 1991

Relative quantification in proteomics: new approaches for biochemistry

artículo científico publicado en 2006

Ribosome-associated nucleophosmin 1: increased expression and shuttling activity distinguishes prognostic subtypes in chronic lymphocytic leukaemia

article

Role of cytokines and extracellular matrix in the regulation of haemopoietic stem cells

artículo científico publicado en 1998

Role of the C-terminal actin binding domain in BCR/ABL-mediated survival and drug resistance.

artículo científico publicado en 2006

SRC-induced disassembly of adherens junctions requires localized phosphorylation and degradation of the rac activator tiam1.

artículo científico publicado en 2009

Simultaneous analysis of relative protein expression levels across multiple samples using iTRAQ isobaric tags with 2D nano LC–MS/MS ⬇️

artículo científico publicado el 26 de agosto de 2010

Statistical considerations of optimal study design for human plasma proteomics and biomarker discovery

artículo científico publicado en 2012

Stem cells bank on ATM machine

artículo científico publicado en 2004

Systematic proteome and transcriptome analysis of stem cell populations

artículo científico publicado en 2006

Systems-level dynamic analyses of fate change in murine embryonic stem cells

artículo científico publicado en 2009

THOC5 controls 3'end-processing of immediate early genes via interaction with polyadenylation specific factor 100 (CPSF100).

artículo científico publicado en 2014

THOC5 couples M-CSF receptor signaling to transcription factor expression

artículo científico publicado en 2009

THOC5 spliceosome protein: a target for leukaemogenic tyrosine kinases that affects inositol lipid turnover

artículo científico publicado en 2008

THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo

scientific journal article

The M-CSF receptor substrate and interacting protein FMIP is governed in its subcellular localization by protein kinase C-mediated phosphorylation, and thereby potentiates M-CSF-mediated differentiation

scientific journal article

The antiproliferative activity of kinase inhibitors in chronic myeloid leukemia cells is mediated by FOXO transcription factors

artículo científico publicado en 2014

The application of a hypothesis-driven strategy to the sensitive detection and location of acetylated lysine residues.

artículo científico publicado en 2007

The application of quantification techniques in proteomics for biomedical research

artículo científico

The biology and clinical potential of growth factors that regulate myeloid cell production.

artículo científico

The methyltransferase WBSCR22/Merm1 enhances glucocorticoid receptor function and is regulated in lung inflammation and cancer ⬇️

artículo científico publicado en 2014

The phorbol ester, TPA inhibits glucagon-stimulated adenylate cyclase activity

scientific article published on 01 May 1984

The potential for proteomic definition of stem cell populations

artículo científico publicado en 2003

The requirement for proteomics to unravel stem cell regulatory mechanisms

artículo científico

The rho-kinase inhibitors Y-27632 and fasudil act synergistically with imatinib to inhibit the expansion of ex vivo CD34(+) CML progenitor cells.

artículo científico publicado en 2007

The role of the tumor-microenvironment in lung cancer-metastasis and its relationship to potential therapeutic targets

artículo científico

The survival of differentiating embryonic stem cells is dependent on the SCF-KIT pathway

artículo científico publicado en 2006

The thermodependence of the activity of integral enzymes in liver plasma membranes

artículo científico publicado en 1982

The time is right: proteome biology of stem cells

artículo científico publicado en 2008

The use of isobaric tag peptide labeling (iTRAQ) and mass spectrometry to examine rare, primitive hematopoietic cells from patients with chronic myeloid leukemia

artículo científico publicado en 2007

The use of proteomics for systematic analysis of normal and transformed hematopoietic stem cells

artículo científico

Thermotropic lipid phase separations in human platelet and rat liver plasma membranes

artículo científico publicado en 1983

Transcriptional regulation of immediate-early gene response by THOC5, a member of mRNA export complex, contributes to the M-CSF-induced macrophage differentiation

artículo científico publicado en 2013

Transglutaminase 2 expression in acute myeloid leukemia: association with adhesion molecule expression and leukemic blast motility

artículo científico publicado en 2013

v-Abl-mediated apoptotic suppression is associated with SHC phosphorylation without concomitant mitogen-activated protein kinase activation.

artículo científico publicado en 1995

Lista de obras de Anthony D Whetton

5′-Nucleotidase is activated upon cholesterol-depletion of liver plasma membranes

A combined biomarker panel shows improved sensitivity for the early detection of ovarian cancer allowing the identification of the most aggressive type II tumours.

A comparison of the effect of bcr/abl breakpoint specific phosphothiorate oligodeoxynucleotides on colony formation by bcr/abl positive and negative, CD34 enriched mononuclear cell populations

A gel-free quantitative proteomics analysis of factors released from hypoxic-conditioned placentae

A hierarchical statistical modeling approach to analyze proteomic isobaric tag for relative and absolute quantitation data

A label-free selected reaction monitoring workflow identifies a subset of pregnancy specific glycoproteins as potential predictive markers of early-onset pre-eclampsia

A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response

A novel mechanism for BCR-ABL action: stimulated secretion of CCN3 is involved in growth and differentiation regulation

A pathway from leukemogenic oncogenes and stem cell chemokines to RNA processing via THOC5.

A proof-of-principle gel-free proteomics strategy for the identification of predictive biomarkers for the onset of pre-eclampsia

A proteomic analysis of murine bone marrow and its response to ionizing radiation.

A sensitive mass spectrometric method for hypothesis-driven detection of peptide post-translational modifications: multiple reaction monitoring-initiated detection and sequencing (MIDAS).

A specific PTPRC/CD45 phosphorylation event governed by stem cell chemokine CXCL12 regulates primitive hematopoietic cell motility

AXL Inhibition Extinguishes Primitive JAK2 Mutated Myeloproliferative Neoplasm Progenitor Cells

Acquired cross-linker resistance associated with a novel spliced BRCA2 protein variant for molecular phenotyping of BRCA2 disruption.

Adenosine triphosphate can maintain multipotent haemopoietic stem cells in the absence of interleukin 3 via a membrane permeabilization mechanism

Amplification and translocation of 3q26 with overexpression of EVI1 in Fanconi anemia-derived childhood acute myeloid leukemia with biallelic FANCD1/BRCA2 disruption

An assessment of peptide enrichment methods employing mTRAQ quantification approaches

An ataxia-telangiectasia-mutated (ATM) kinase mediated response to DNA damage down-regulates the mRNA-binding potential of THOC5

Antibody-based detection of protein phosphorylation status to track the efficacy of novel therapies using nanogram protein quantities from stem cells and cell lines.

Apoptosis is regulated by the rate of glucose transport in an interleukin 3 dependent cell line

Application of the MIDAS Approach for Analysis of Lysine Acetylation Sites

Application of two-dimensional difference gel electrophoresis to studying bone marrow macrophages and their in vivo responses to ionizing radiation.

Assessment of downstream effectors of BCR/ABL protein tyrosine kinase using combined proteomic approaches

BCR-ABL affects STAT5A and STAT5B differentially

BCR/ABL modulates protein phosphorylation associated with the etoposide-induced DNA damage response

Bcr-Abl-mediated molecular mechanism for apoptotic suppression in multipotent haemopoietic cells: a role for PKCbetaII.

Candidate plasma biomarkers for predicting ascending aortic aneurysm in bicuspid aortic valve disease.

Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation.

Chronic myeloid leukemia CD34+ cells have elevated levels of phosphatidylinositol 3,4,5 trisphosphate (PtdIns(3,4,5)P3) and lack a PtdIns(3,4,5)P3 response to cytokines and chemotactic factors; effects reversed by imatinib.

Comparative proteomics of primitive hematopoietic cell populations reveals differences in expression of proteins regulating motility

Comparative quantification of the surfaceome of human multipotent mesenchymal progenitor cells.

Cord Blood-Derived Quiescent CD34+ Cells Are More Transcriptionally Matched to AML Blasts Than Cytokine-Induced Normal Human Hematopoietic CD34+ Cells

Data Independent Acquisition Mass Spectrometry Can Identify Circulating Proteins That Predict Future Weight Loss with a Diet and Exercise Programme

Development of Multipotential Haemopoietic Stem Cells to Neutrophils is Associated with Increased Expression of Receptors for Granulocyte Macrophage Colony-Stimulating Factor: Altered Biological Responses to GM-CSF during Development ⬇️

Development of a selected reaction monitoring mass spectrometry-based assay to detect asparaginyl endopeptidase activity in biological fluids

Development of approaches for systematic analysis of protein networks in stem cells

Developmental fate determination and marker discovery in hematopoietic stem cell biology using proteomic fingerprinting

Diagnosis of epithelial ovarian cancer using a combined protein biomarker panel

Differential effect of leukaemogenic tyrosine kinases on cell motility is governed by subcellular localisation.

Dimethylnitrosamine inhibits the glucagon-stimulated adenylate cyclase activity of rat liver plasma membranes and decreases plasma membrane fluidity

Discovery and Evaluation of Protein Biomarkers as a Signature of Wellness in Late-Stage Cancer Patients in Early Phase Clinical Trials

Discovery and Validation of Predictive Biomarkers of Survival for Non-small Cell Lung Cancer Patients Undergoing Radical Radiotherapy: Two Proteins With Predictive Value

Drosophila F-BAR protein Syndapin contributes to coupling the plasma membrane and contractile ring in cytokinesis

Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells

ERK and AKT phosphorylation status in lung cancer and emphysema using nanocapillary isoelectric focusing

EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association

Effect of haematopoietic cell growth factor on intracellular ATP levels.

Eight-channel iTRAQ enables comparison of the activity of six leukemogenic tyrosine kinases

FMIP controls the adipocyte lineage commitment of C2C12 cells by downmodulation of C/EBP alpha.

Fanconi anemia (FA)-associated 3q gains in leukemic transformation consistently target EVI1, but do not affect low TERC expression in FA

Flt3 ligand can promote survival and macrophage development without proliferation in myeloid progenitor cells

Forskolin and ethanol both perturb the structure of liver plasma membranes and activate adenylate cyclase activity.

Further characterisation of the in situ terminal deoxynucleotidyl transferase (TdT) assay for the flow cytometric analysis of apoptosis in drug resistant and drug sensitive leukaemic cells.

Generation of a conditionally immortalized myeloid progenitor cell line requiring the presence of both interleukin-3 and stem cell factor to survive and proliferate

Genome-wide analysis of transcriptional reprogramming in mouse models of acute myeloid leukaemia

Global effects of BCR/ABL and TEL/PDGFRbeta expression on the proteome and phosphoproteome: identification of the Rho pathway as a target of BCR/ABL.

Glucocorticoid receptor isoforms direct distinct mitochondrial programs to regulate ATP production ⬇️

Glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy.

Glucose transport regulation by p210 Bcr-Abl in a chronic myeloid leukaemia model.

Guanidination chemistry for qualitative and quantitative proteomics

Haemopoietic growth factors

Heterozygote FANCD2 mutations associated with childhood T Cell ALL and testicular seminoma

Homing and mobilization in the stem cell niche.

How will haematologists use proteomics?

Hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival.

Identification of a Biomarker Panel for Early Detection of Lung Cancer Patients

Identification of nuclear protein targets for six leukemogenic tyrosine kinases governed by post-translational regulation

Identification of primary structural features that define the differential actions of IL-3 and GM-CSF receptors

Integrated nuclear proteomics and transcriptomics identifies S100A4 as a therapeutic target in acute myeloid leukemia

Interleukin-3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface

Is Serum or Plasma More Appropriate for Intersubject Comparisons in Metabolomic Studies? An Assessment in Patients with Small-Cell Lung Cancer

JAK2/STAT5 inhibition by nilotinib with ruxolitinib contributes to the elimination of CML CD34+ cells in vitro and in vivo.

Liquid chromatography-mass spectrometry calibration transfer and metabolomics data fusion

Lysophospholipids synergistically promote primitive hematopoietic cell chemotaxis via a mechanism involving Vav 1

MPL W515L expression induces TGFβ secretion and leads to an increase in chemokinesis via phosphorylation of THOC5.

Macrophage inflammatory protein-1 alpha mediated growth inhibition in a haemopoietic stem cell line is associated with inositol 1,4,5 triphosphate generation.

Models to Study Chronic Myeloid Leukemia Cancer Stem Cells

Modern trends in human leukemia VI. Wilsede, June 17-21, 1984.