Lista de obras - Sarah Pendergrass - Dominio Público Uruguay

A Phenome-Wide Association Study Uncovers a Role for Autoimmunity in the Development of Chronic Obstructive Pulmonary Disease.

artículo científico publicado en 2018

A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids.

artículo científico publicado en 2019

A catalog of genetic loci associated with kidney function from analyses of a million individuals

scientific article published on 31 May 2019

A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response

artículo científico publicado en 2009

A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans

artículo científico publicado en 2019

A phenome-wide association study to discover pleiotropic effects of , , and

A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains

artículo científico publicado en 2011

A simulation study investigating power estimates in phenome-wide association studies

artículo científico publicado en 2018

ATHENA: the analysis tool for heritable and environmental network associations

artículo científico publicado en 2013

Antagonistic effect of the matricellular signaling protein CCN3 on TGF-beta- and Wnt-mediated fibrillinogenesis in systemic sclerosis and Marfan syndrome.

artículo científico publicado en 2010

Association of the FTO obesity risk variant rs8050136 with percentage of energy intake from fat in multiple racial/ethnic populations: the PAGE study

artículo científico publicado en 2013

Author Correction: Rare variants in drug target genes contributing to complex diseases, phenome-wide

artículo científico publicado en 2018

BioBin: a bioinformatics tool for automating the binning of rare variants using publicly available biological knowledge

artículo científico publicado en 2013

Biology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network

artículo científico publicado en 2015

Characterization of mitochondrial haplogroups in a large population-based sample from the United States

artículo científico publicado en 2014

Characterizing and Managing Missing Structured Data in Electronic Health Records: Data Analysis

artículo científico publicado en 2018

Comparative evaluation of strain-based and model-based modulus elastography

artículo científico publicado en 2005

Consistent directions of effect for established type 2 diabetes risk variants across populations: the population architecture using Genomics and Epidemiology (PAGE) Consortium

artículo científico publicado en 2012

Contrasting Association Results between Existing PheWAS Phenotype Definition Methods and Five Validated Electronic Phenotypes

artículo científico publicado en 2015

Correction: Molecular Subsets in the Gene Expression Signatures of Scleroderma Skin.

artículo científico publicado en 2008

Detecting and Characterizing Pleiotropy: New Methods for Uncovering the Connection Between the Complexity of Genomic Architecture and Multiple phenotypes

artículo científico publicado en 2014

Detecting potential pleiotropy across cardiovascular and neurological diseases using univariate, bivariate, and multivariate methods on 43,870 individuals from the eMERGE network

Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study

artículo científico publicado en 2014

Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study

artículo científico publicado en 2016

Diverse convergent evidence in the genetic analysis of complex disease: coordinating omic, informatic, and experimental evidence to better identify and validate risk factors

artículo científico publicado en 2014

Electronic health record phenotype in subjects with genetic variants associated with arrhythmogenic right ventricular cardiomyopathy: a study of 30,716 subjects with exome sequencing

artículo científico publicado en 2017

Enabling high-throughput genotype-phenotype associations in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project as part of the Population Architecture using Genomics and Epidemiology (PAGE) study

artículo científico publicado en 2013

Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield Personalized Medicine Research Project Biobank

artículo científico publicado en 2014

Evidence for extensive pleiotropy among pharmacogenes

scientific article published on June 2016

First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring

artículo científico publicado en 2017

Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study

artículo científico publicado en 2011

Genetic variants associated with fasting glucose and insulin concentrations in an ethnically diverse population: results from the Population Architecture using Genomics and Epidemiology (PAGE) study

artículo científico publicado en 2013

Genome-wide analysis of mRNAs bound to the histone stem-loop binding protein

artículo científico publicado en 2006

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

artículo científico publicado en 2019

Genomic analyses with biofilter 2.0: knowledge driven filtering, annotation, and model development

artículo científico publicado en 2013

Genomic architecture of pharmacological efficacy and adverse events

artículo científico publicado en 2014

IDENTIFYING GENETIC ASSOCIATIONS WITH VARIABILITY IN METABOLIC HEALTH AND BLOOD COUNT LABORATORY VALUES: DIVING INTO THE QUANTITATIVE TRAITS BY LEVERAGING LONGITUDINAL DATA FROM AN EHR.

artículo científico publicado en 2016

INTEGRATING CLINICAL LABORATORY MEASURES AND ICD-9 CODE DIAGNOSES IN PHENOME-WIDE ASSOCIATION STUDIES.

artículo científico publicado en 2016

Interferon and alternative activation of monocyte/macrophages in systemic sclerosis-associated pulmonary arterial hypertension.

artículo científico publicado en 2011

Intrinsic gene expression subsets of diffuse cutaneous systemic sclerosis are stable in serial skin biopsies.

artículo científico publicado en 2012

Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studies

artículo científico publicado en 2014

Knowledge-driven genomic interactions: an application in ovarian cancer

artículo científico publicado en 2014

Leveraging Epidemiologic and Clinical Collections for Genomic Studies of Complex Traits

artículo científico publicado en 2015

Limited systemic sclerosis patients with pulmonary arterial hypertension show biomarkers of inflammation and vascular injury

artículo científico publicado en 2010

Low frequency variants, collapsed based on biological knowledge, uncover complexity of population stratification in 1000 genomes project data

artículo científico publicado en 2013

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci ⬇️

artículo científico publicado en 2016

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

artículo científico publicado en 2020

Methods of integrating data to uncover genotype-phenotype interactions

artículo científico publicado en 2015

Microwave thermal imaging: initial in vivo experience with a single heating zone

artículo científico publicado en 2003

Molecular subsets in the gene expression signatures of scleroderma skin

artículo científico publicado en 2008

Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study

artículo científico publicado en 2014

Multiphenotype association study of patients randomized to initiate antiretroviral regimens in AIDS Clinical Trials Group protocol A5202.

artículo científico publicado en 2017

Next-generation analysis of cataracts: determining knowledge driven gene-gene interactions using Biofilter, and gene-environment interactions using the PhenX Toolkit.

artículo científico publicado en 2013

Next-generation analysis of cataracts: determining knowledge driven gene-gene interactions using biofilter, and gene-environment interactions using the Phenx Toolkit*.

artículo científico publicado en 2015

OPENING THE DOOR TO THE LARGE SCALE USE OF CLINICAL LAB MEASURES FOR ASSOCIATION TESTING: EXPLORING DIFFERENT METHODS FOR DEFINING PHENOTYPES.

artículo científico publicado en 2016

PATTERNS IN BIOMEDICAL DATA-HOW DO WE FIND THEM?

artículo científico publicado en 2016

PHENOME-WIDE INTERACTION STUDY (PheWIS) IN AIDS CLINICAL TRIALS GROUP DATA (ACTG).

artículo científico publicado en 2016

PLATO software provides analytic framework for investigating complexity beyond genome-wide association studies

artículo científico publicado en 2017

Pathway analysis by randomization incorporating structure-PARIS: an update

artículo científico publicado en 2016

PheWAS and Beyond: The Landscape of Associations with Medical Diagnoses and Clinical Measures across 38,662 Individuals from Geisinger

artículo científico publicado en 2018

Phenome-Wide Association Studies: Embracing Complexity for Discovery

artículo científico publicado en 2015

Phenome-Wide Association Study to Explore Relationships between Immune System Related Genetic Loci and Complex Traits and Diseases

artículo científico publicado en 2016

Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols

artículo científico publicado en 2015

Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index

artículo científico publicado en 2014

Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network

artículo científico publicado en 2013

Pleiotropic genes for metabolic syndrome and inflammation

artículo científico publicado en 2014

Polygenic heritability estimates in pharmacogenetics: focus on asthma and related phenotypes

artículo científico publicado en 2013

Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance).

artículo científico publicado en 2014

Rare variants in drug target genes contributing to complex diseases, phenome-wide

artículo científico publicado en 2018

Real world scenarios in rare variant association analysis: the impact of imbalance and sample size on the power in silico

Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activity

artículo científico publicado en 2014

Synthesis-View: visualization and interpretation of SNP association results for multi-cohort, multi-phenotype data and meta-analysis

artículo científico publicado en 2010

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

artículo científico publicado en 2013

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

artículo científico publicado en 2019

The detection and characterization of pleiotropy: discovery, progress, and promise

artículo científico

The importance of buprenorphine research in the opioid crisis

artículo científico publicado en 2019

The joint effect of air pollution exposure and copy number variation on risk for autism.

artículo científico publicado en 2017

Towards a phenome-wide catalog of human clinical traits impacted by genetic ancestry.

artículo científico publicado en 2015

Uncovering the etiology of autism spectrum disorders: genomics, bioinformatics, environment, data collection and exploration, and future possibilities

artículo científico publicado en 2014

Understanding systemic sclerosis through gene expression profiling

artículo científico publicado en 2007

Unfolding of hidden white blood cell count phenotypes for gene discovery using latent class mixed modeling

article

Using Adipose Measures from Health Care Provider-Based Imaging Data for Discovery

Using BioBin to explore rare variant population stratification

artículo científico publicado en 2013

Visual integration of results from a large DNA biobank (BioVU) using synthesis-view

artículo científico publicado en 2011

Visualizing genomic information across chromosomes with PhenoGram

artículo científico publicado en 2013

Visually integrating and exploring high throughput Phenome-Wide Association Study (PheWAS) results using PheWAS-View

artículo científico publicado en 2012

eMERGE Phenome-Wide Association Study (PheWAS) identifies clinical associations and pleiotropy for stop-gain variants

artículo científico publicado en 2016

Lista de obras de Sarah Pendergrass

A Phenome-Wide Association Study Uncovers a Role for Autoimmunity in the Development of Chronic Obstructive Pulmonary Disease.

A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids.

A catalog of genetic loci associated with kidney function from analyses of a million individuals

A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response

A phenome-wide association study (PheWAS) in the Population Architecture using Genomics and Epidemiology (PAGE) study reveals potential pleiotropy in African Americans

A phenome-wide association study to discover pleiotropic effects of , , and

A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains

A simulation study investigating power estimates in phenome-wide association studies

ATHENA: the analysis tool for heritable and environmental network associations

Antagonistic effect of the matricellular signaling protein CCN3 on TGF-beta- and Wnt-mediated fibrillinogenesis in systemic sclerosis and Marfan syndrome.

Association of the FTO obesity risk variant rs8050136 with percentage of energy intake from fat in multiple racial/ethnic populations: the PAGE study

Author Correction: Rare variants in drug target genes contributing to complex diseases, phenome-wide

BioBin: a bioinformatics tool for automating the binning of rare variants using publicly available biological knowledge

Biology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network

Characterization of mitochondrial haplogroups in a large population-based sample from the United States

Characterizing and Managing Missing Structured Data in Electronic Health Records: Data Analysis

Comparative evaluation of strain-based and model-based modulus elastography

Consistent directions of effect for established type 2 diabetes risk variants across populations: the population architecture using Genomics and Epidemiology (PAGE) Consortium

Contrasting Association Results between Existing PheWAS Phenotype Definition Methods and Five Validated Electronic Phenotypes

Correction: Molecular Subsets in the Gene Expression Signatures of Scleroderma Skin.

Detecting and Characterizing Pleiotropy: New Methods for Uncovering the Connection Between the Complexity of Genomic Architecture and Multiple phenotypes

Detecting potential pleiotropy across cardiovascular and neurological diseases using univariate, bivariate, and multivariate methods on 43,870 individuals from the eMERGE network

Detection of pleiotropy through a Phenome-wide association study (PheWAS) of epidemiologic data as part of the Environmental Architecture for Genes Linked to Environment (EAGLE) study

Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study

Diverse convergent evidence in the genetic analysis of complex disease: coordinating omic, informatic, and experimental evidence to better identify and validate risk factors

Electronic health record phenotype in subjects with genetic variants associated with arrhythmogenic right ventricular cardiomyopathy: a study of 30,716 subjects with exome sequencing

Enabling high-throughput genotype-phenotype associations in the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) project as part of the Population Architecture using Genomics and Epidemiology (PAGE) study

Environment-wide association study (EWAS) for type 2 diabetes in the Marshfield Personalized Medicine Research Project Biobank

Evidence for extensive pleiotropy among pharmacogenes

First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring

Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study

Genetic variants associated with fasting glucose and insulin concentrations in an ethnically diverse population: results from the Population Architecture using Genomics and Epidemiology (PAGE) study

Genome-wide analysis of mRNAs bound to the histone stem-loop binding protein

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

Genomic analyses with biofilter 2.0: knowledge driven filtering, annotation, and model development

Genomic architecture of pharmacological efficacy and adverse events

IDENTIFYING GENETIC ASSOCIATIONS WITH VARIABILITY IN METABOLIC HEALTH AND BLOOD COUNT LABORATORY VALUES: DIVING INTO THE QUANTITATIVE TRAITS BY LEVERAGING LONGITUDINAL DATA FROM AN EHR.

INTEGRATING CLINICAL LABORATORY MEASURES AND ICD-9 CODE DIAGNOSES IN PHENOME-WIDE ASSOCIATION STUDIES.

Interferon and alternative activation of monocyte/macrophages in systemic sclerosis-associated pulmonary arterial hypertension.

Intrinsic gene expression subsets of diffuse cutaneous systemic sclerosis are stable in serial skin biopsies.

Investigating the relationship between mitochondrial genetic variation and cardiovascular-related traits to develop a framework for mitochondrial phenome-wide association studies

Knowledge-driven genomic interactions: an application in ovarian cancer

Leveraging Epidemiologic and Clinical Collections for Genomic Studies of Complex Traits

Limited systemic sclerosis patients with pulmonary arterial hypertension show biomarkers of inflammation and vascular injury

Low frequency variants, collapsed based on biological knowledge, uncover complexity of population stratification in 1000 genomes project data

Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci ⬇️

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline

Methods of integrating data to uncover genotype-phenotype interactions

Microwave thermal imaging: initial in vivo experience with a single heating zone

Molecular subsets in the gene expression signatures of scleroderma skin

Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study

Multiphenotype association study of patients randomized to initiate antiretroviral regimens in AIDS Clinical Trials Group protocol A5202.

Next-generation analysis of cataracts: determining knowledge driven gene-gene interactions using Biofilter, and gene-environment interactions using the PhenX Toolkit.

Next-generation analysis of cataracts: determining knowledge driven gene-gene interactions using biofilter, and gene-environment interactions using the Phenx Toolkit*.

OPENING THE DOOR TO THE LARGE SCALE USE OF CLINICAL LAB MEASURES FOR ASSOCIATION TESTING: EXPLORING DIFFERENT METHODS FOR DEFINING PHENOTYPES.

PATTERNS IN BIOMEDICAL DATA-HOW DO WE FIND THEM?

PHENOME-WIDE INTERACTION STUDY (PheWIS) IN AIDS CLINICAL TRIALS GROUP DATA (ACTG).

PLATO software provides analytic framework for investigating complexity beyond genome-wide association studies

Pathway analysis by randomization incorporating structure-PARIS: an update

PheWAS and Beyond: The Landscape of Associations with Medical Diagnoses and Clinical Measures across 38,662 Individuals from Geisinger

Phenome-Wide Association Studies: Embracing Complexity for Discovery

Phenome-Wide Association Study to Explore Relationships between Immune System Related Genetic Loci and Complex Traits and Diseases

Phenome-wide Association Study Relating Pretreatment Laboratory Parameters With Human Genetic Variants in AIDS Clinical Trials Group Protocols

Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index

Phenome-wide association study (PheWAS) for detection of pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network

Pleiotropic genes for metabolic syndrome and inflammation

Polygenic heritability estimates in pharmacogenetics: focus on asthma and related phenotypes

Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance).

Rare variants in drug target genes contributing to complex diseases, phenome-wide

Real world scenarios in rare variant association analysis: the impact of imbalance and sample size on the power in silico

Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activity

Synthesis-View: visualization and interpretation of SNP association results for multi-cohort, multi-phenotype data and meta-analysis

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

The detection and characterization of pleiotropy: discovery, progress, and promise

The importance of buprenorphine research in the opioid crisis

The joint effect of air pollution exposure and copy number variation on risk for autism.

Towards a phenome-wide catalog of human clinical traits impacted by genetic ancestry.

Uncovering the etiology of autism spectrum disorders: genomics, bioinformatics, environment, data collection and exploration, and future possibilities