Lista de obras - Naoki Umezawa - Dominio Público Uruguay

(alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions

artículo científico publicado en 2007

A fluorescence polarization assay for the identification of inhibitors of the p53-DM2 protein-protein interaction

scientific article published on 01 January 2002

A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model.

artículo científico publicado en 2018

A versatile strategy for the synthesis of crown ether-bearing heterocycles: discovery of calcium-selective fluoroionophore

artículo científico publicado en 2007

Activation of lysine-specific demethylase 1 inhibitor peptide by redox-controlled cleavage of a traceless linker.

artículo científico publicado en 2016

Active oxygen species generated from photoexcited fullerene (C60) as potential medicines: O2-* versus 1O2.

artículo científico publicado en 2003

Active site geometry of a novel aminopropyltransferase for biosynthesis of hyperthermophile-specific branched-chain polyamine

artículo científico publicado en 2017

Biogenic triamine and tetraamine activate core catalytic ability of Tetrahymena group I ribozyme in the absence of its large activator module

artículo científico publicado en 2018

Branched-Chain Polyamine Found in Hyperthermophiles Induces Unique Temperature-Dependent Structural Changes in Genome-Size DNA

artículo científico publicado en 2018

Chimeric (alpha/beta + alpha)-peptide ligands for the BH3-recognition cleft of Bcl-XL: critical role of the molecular scaffold in protein surface recognition

artículo científico publicado en 2005

Comparative study of polyethylene polyamines as activator molecules for a structurally unstable group I ribozyme.

artículo científico publicado en 2018

Design and synthesis of a 4-aminoquinoline-based molecular tweezer that recognizes protoporphyrin IX and iron(iii) protoporphyrin IX and its application as a supramolecular photosensitizer

artículo científico publicado en 2018

Design of New Extraction Surfactants for Membrane Proteins from Peptide Gemini Surfactants.

artículo científico publicado en 2016

Design, synthesis, and evaluation of new type of L-amino acids containing pyridine moiety as nitric oxide synthase inhibitor.

artículo científico publicado en 2006

Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1.

artículo científico publicado en 2017

Development of Cell-Penetration PG-Surfactants and Its Application in External Peptide Delivery to Cytosol

scientific article published on 29 January 2020

Effect of helical conformation and side chain structure on γ-secretase inhibition by β-peptide foldamers: insight into substrate recognition.

artículo científico publicado en 2013

Effect of the o-Acetamido Group on pH-Dependent Light Emission of a 3-Hydroxyphenyl-Substituted Dioxetane Luminophore

artículo científico publicado en 2019

Enhanced catalase-like activity of manganese salen complexes in water: effect of a three-dimensionally fixed auxiliary

scientific article published on 09 October 2006

Evaluation of 3-substituted arginine analogs as selective inhibitors of human nitric oxide synthase isozymes.

artículo científico publicado en 2005

Extreme rate acceleration by axial thiolate coordination on the isomerization of endoperoxide catalyzed by iron porphyrin

artículo científico publicado en 2008

Facile synthesis of peptide-porphyrin conjugates: Towards artificial catalase.

artículo científico publicado en 2010

Identification of a novel aminopropyltransferase involved in the synthesis of branched-chain polyamines in hyperthermophiles.

artículo científico publicado en 2014

Inhibition of gamma-secretase activity by helical beta-peptide foldamers.

artículo científico publicado en 2009

Interactions of the antimicrobial beta-peptide beta-17 with phospholipid vesicles differ from membrane interactions of magainins

scientific article published on 01 March 2003

Manganese salen complexes with acid-base catalytic auxiliary: functional mimetics of catalase

scientific article published on 12 March 2013

Methylene chain ruler for evaluating the regioselectivity of a substrate-recognising oxidation catalyst

artículo científico publicado en 2019

Naturally occurring branched-chain polyamines induce a crosslinked meshwork structure in a giant DNA.

artículo científico publicado en 2016

Nitrous oxide reduction-coupled alkene-alkene coupling catalysed by metalloporphyrins.

artículo científico publicado en 2013

Novel probes showing specific fluorescence enhancement on binding to a hexahistidine tag.

artículo científico publicado en 2008

On-bead fluorescence assay for serine/threonine kinases

artículo científico publicado en 2005

Participation of reactive oxygen species in phototoxicity induced by quinolone antibacterial agents

artículo científico publicado en 1997

Photocontrol of Peptide function: backbone cyclization strategy with photocleavable amino Acid.

artículo científico publicado en 2011

Rational design of fluorescein-based fluorescence probes. Mechanism-based design of a maximum fluorescence probe for singlet oxygen.

artículo científico publicado en 2001

Role of Thiolate Ligand in Spin State and Redox Switching in the Cytochrome P450 Catalytic Cycle.

artículo científico publicado en 2017

Selective Binding of TAR RNA by a Tat-Derived β-Peptide

artículo científico publicado en 2003

Selective recognition and detection of biomacromolecules utilizing chemical property of amino Acid or Peptide

artículo científico publicado en 2007

Stable Iron Porphyrin Intramolecularly Coordinated by Alcoholate Anion: Synthesis and Evaluation of Axial Ligand Effect of Alcoholate on Spectroscopy and Catalytic Activity

scientific article published on 21 March 2019

Structurally Diverse Polyamines: Solid-Phase Synthesis and Interaction with DNA

artículo científico publicado en 2015

Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1

artículo científico publicado en 2010

Synthesis of the carbon framework of scholarisine A by intramolecular oxidative coupling.

artículo científico publicado en 2013

Translocation of a beta-peptide across cell membranes

artículo científico publicado en 2002

Unique oxidation reaction of amides with pyridine-N-oxide catalyzed by ruthenium porphyrin: direct oxidative conversion of N-acyl-L-proline to N-acyl-L-glutamate.

artículo científico publicado en 2005

Lista de obras de Naoki Umezawa

(alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions

A fluorescence polarization assay for the identification of inhibitors of the p53-DM2 protein-protein interaction

A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model.

A versatile strategy for the synthesis of crown ether-bearing heterocycles: discovery of calcium-selective fluoroionophore

Activation of lysine-specific demethylase 1 inhibitor peptide by redox-controlled cleavage of a traceless linker.

Active oxygen species generated from photoexcited fullerene (C60) as potential medicines: O2-* versus 1O2.

Active site geometry of a novel aminopropyltransferase for biosynthesis of hyperthermophile-specific branched-chain polyamine

Biogenic triamine and tetraamine activate core catalytic ability of Tetrahymena group I ribozyme in the absence of its large activator module

Branched-Chain Polyamine Found in Hyperthermophiles Induces Unique Temperature-Dependent Structural Changes in Genome-Size DNA

Chimeric (alpha/beta + alpha)-peptide ligands for the BH3-recognition cleft of Bcl-XL: critical role of the molecular scaffold in protein surface recognition

Comparative study of polyethylene polyamines as activator molecules for a structurally unstable group I ribozyme.

Design and synthesis of a 4-aminoquinoline-based molecular tweezer that recognizes protoporphyrin IX and iron(iii) protoporphyrin IX and its application as a supramolecular photosensitizer

Design of New Extraction Surfactants for Membrane Proteins from Peptide Gemini Surfactants.

Design, synthesis, and evaluation of new type of L-amino acids containing pyridine moiety as nitric oxide synthase inhibitor.

Development and crystallographic evaluation of histone H3 peptide with N-terminal serine substitution as a potent inhibitor of lysine-specific demethylase 1.

Development of Cell-Penetration PG-Surfactants and Its Application in External Peptide Delivery to Cytosol

Effect of helical conformation and side chain structure on γ-secretase inhibition by β-peptide foldamers: insight into substrate recognition.

Effect of the o-Acetamido Group on pH-Dependent Light Emission of a 3-Hydroxyphenyl-Substituted Dioxetane Luminophore

Enhanced catalase-like activity of manganese salen complexes in water: effect of a three-dimensionally fixed auxiliary

Evaluation of 3-substituted arginine analogs as selective inhibitors of human nitric oxide synthase isozymes.

Extreme rate acceleration by axial thiolate coordination on the isomerization of endoperoxide catalyzed by iron porphyrin

Facile synthesis of peptide-porphyrin conjugates: Towards artificial catalase.

Identification of a novel aminopropyltransferase involved in the synthesis of branched-chain polyamines in hyperthermophiles.

Inhibition of gamma-secretase activity by helical beta-peptide foldamers.

Interactions of the antimicrobial beta-peptide beta-17 with phospholipid vesicles differ from membrane interactions of magainins

Manganese salen complexes with acid-base catalytic auxiliary: functional mimetics of catalase

Methylene chain ruler for evaluating the regioselectivity of a substrate-recognising oxidation catalyst

Naturally occurring branched-chain polyamines induce a crosslinked meshwork structure in a giant DNA.

Nitrous oxide reduction-coupled alkene-alkene coupling catalysed by metalloporphyrins.

Novel probes showing specific fluorescence enhancement on binding to a hexahistidine tag.

On-bead fluorescence assay for serine/threonine kinases

Participation of reactive oxygen species in phototoxicity induced by quinolone antibacterial agents

Photocontrol of Peptide function: backbone cyclization strategy with photocleavable amino Acid.

Rational design of fluorescein-based fluorescence probes. Mechanism-based design of a maximum fluorescence probe for singlet oxygen.

Role of Thiolate Ligand in Spin State and Redox Switching in the Cytochrome P450 Catalytic Cycle.

Selective Binding of TAR RNA by a Tat-Derived β-Peptide

Selective recognition and detection of biomacromolecules utilizing chemical property of amino Acid or Peptide

Stable Iron Porphyrin Intramolecularly Coordinated by Alcoholate Anion: Synthesis and Evaluation of Axial Ligand Effect of Alcoholate on Spectroscopy and Catalytic Activity

Structurally Diverse Polyamines: Solid-Phase Synthesis and Interaction with DNA

Structurally designed trans-2-phenylcyclopropylamine derivatives potently inhibit histone demethylase LSD1/KDM1

Synthesis of the carbon framework of scholarisine A by intramolecular oxidative coupling.

Translocation of a beta-peptide across cell membranes

Unique oxidation reaction of amides with pyridine-N-oxide catalyzed by ruthenium porphyrin: direct oxidative conversion of N-acyl-L-proline to N-acyl-L-glutamate.