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Lista de obras de Edwin R Chilvers

99mTechnetium-labelled neutrophil scanning in pneumonia.

artículo científico publicado en 2009

A case of refractory hypoxaemia.

artículo científico publicado en 2008

A comparison of the effects of SCA40, NS 004 and NS 1619 on large conductance Ca(2+)-activated K+ channels in bovine tracheal smooth muscle cells in culture.

artículo científico publicado en 1995

A novel RASA1 mutation causing capillary malformation-arteriovenous malformation (CM-AVM) presenting during pregnancy

artículo científico publicado en 2013

Abdominal pain associated with cranial nerve palsy and peripheral neuropathy.

artículo científico publicado en 1997

Absence of circulating products of oxygen derived free radicals in acute severe asthma

artículo científico publicado en 1989

Acceleration of human neutrophil apoptosis by TRAIL.

artículo científico publicado en 2003

Acute Pancreatitis Mimicking Myocardial Infarction: Potential for Inadvertent Use of Thrombolytic Therapy

scientific article published on 01 October 1993

Acute Respiratory Distress Syndrome Neutrophils Have a Distinct Phenotype and Are Resistant to Phosphoinositide 3-Kinase Inhibition

artículo científico publicado en 2016

Acute lung injury results from failure of neutrophil de-priming: a new hypothesis

artículo científico publicado en 2012

Advances in neutrophil biology: clinical implications

artículo científico publicado en 2008

Agents That Elevate cAMP Inhibit Human Neutrophil Apoptosis

artículo científico publicado en 1995

Allergens as immunomodulatory proteins: the cat dander protein Fel d 1 enhances TLR activation by lipid ligands

artículo científico publicado en 2013

Alveolar Macrophages Isolated Directly From Human Cytomegalovirus (HCMV)-Seropositive Individuals Are Sites of HCMV Reactivation In Vivo

artículo científico publicado en 2014

Aminopeptidase N (CD13) regulates tumor necrosis factor-alpha-induced apoptosis in human neutrophils

artículo científico publicado en 2006

Author's response: co-trimoxazole treatment in idiopathic pulmonary fibrosis

artículo científico publicado en 2013

Azithromycin therapy for neutrophilic airways disease: myth or magic?

artículo científico publicado en 2009

Biomarkers of eosinophilic inflammation in asthma.

artículo científico publicado en 2014

Bone Morphogenetic Protein 9 Enhances Lipopolysaccharide-Induced Leukocyte Recruitment to the Vascular Endothelium

artículo científico publicado en 2016

Bone morphogenetic protein 9 (BMP9) and BMP10 enhance tumor necrosis factor-α-induced monocyte recruitment to the vascular endothelium mainly via activin receptor-like kinase 2.

artículo científico publicado en 2017

Brief communication: identification of the authentic ancient DNA sequence in a human bone contaminated with modern DNA.

artículo científico publicado en 2006

Bronchoalveolar lavage in an immunosuppressed rabbit model of invasive pulmonary aspergillosis

artículo científico publicado en 1989

C13orf31 (FAMIN) is a central regulator of immunometabolic function

artículo científico publicado en 2016

C5a anaphylatoxin and its role in critical illness-induced organ dysfunction

article

Cardiovascular adaptation to hypoxia and the role of peripheral resistance

artículo científico publicado en 2017

Changes in extracellular calcium within the physiological range influence receptor-mediated inositol phosphate responses in brain and tracheal smooth muscle slices

article

Characterisation and Ca2+-dependency of the soluble and particulate Ins(1,4,5)P35-phosphatase in bovine tracheal smooth muscle

artículo científico publicado en 1994

Characterisation of secondary metabolites associated with neutrophil apoptosis

artículo científico publicado en 1996

Characterisation of stereospecific binding sites for inositol 1,4,5-trisphosphate in airway smooth muscle

artículo científico publicado en 1990

Characterization of stereospecific binding sites for [3H]-inositol (1,4,5)-trisphosphate in airway smooth muscle

artículo científico publicado en 1989

Characterization of the survival effect of tumour necrosis factor-alpha in human neutrophils.

artículo científico publicado en 2004

Circulating granulocyte lifespan in compensated alcohol-related cirrhosis: a pilot study

artículo científico publicado en 2016

Clinical and physiological aspects of pulmonary arteriovenous malformations

artículo científico publicado el 1 de marzo de 1988

Clinical application of autologous technetium-99m-labelled eosinophils to detect focal eosinophilic inflammation in the lung

artículo científico publicado en 2015

Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake

artículo científico publicado en 2008

Cystic fibrosis neutrophils have normal intrinsic reactive oxygen species generation.

artículo científico publicado en 2009

Detection of human disease conditions by single-cell morpho-rheological phenotyping of blood.

artículo científico publicado en 2018

Detection of sustained mass increases in inositol 1,3,4,5-tetrakisphosphate in agonist-stimulated airway smooth muscle

scientific article published on 01 April 1991

Determination of mass changes in phosphatidylinositol 4,5-bisphosphate and evidence for agonist-stimulated metabolism of inositol 1,4,5-trisphosphate in airway smooth muscle

artículo científico publicado en 1991

Diagnosing COPD in non-smokers: splitting not lumping

scientific article published on 01 June 2010

Dissociation between respiratory burst activity and deoxyglucose uptake in human neutrophil granulocytes: implications for interpretation of (18)F-FDG PET images.

artículo científico publicado en 2002

Dissociation between β-adrenoceptor-mediated cyclic AMP accumulation and inhibition of histarnine-stimulated phosphoinositide metabolism in airways smooth muscle

scientific article published on 01 May 1997

Distinct responses to hypoxia in subpopulations of distal pulmonary artery cells contribute to pulmonary vascular remodeling in emphysema.

artículo científico publicado en 2012

Disturbed granulocyte macrophage-colony stimulating factor priming of phosphatidylinositol 3,4,5-trisphosphate accumulation and Rac activation in fMLP-stimulated neutrophils from patients with myelodysplasia

artículo científico publicado en 2004

Does P-glycoprotein have a role in the lung clearances of inhaled 99mTc-sestamibi and 99mTc-tetrofosmin?

artículo científico publicado en 2009

Eating their way out of trouble: selective uptake of apoptotic eosinophils by bronchial epithelial cells

artículo científico publicado en 2004

Effect of priming on activation and localization of phospholipase D-1 in human neutrophils

artículo científico publicado en 2004

Effects of S-salbutamol on Human Isolated Bronchus ⬇️

artículo científico publicado el 1 de febrero de 1998

Effects of the cyclin-dependent kinase inhibitor R-roscovitine on eosinophil survival and clearance.

artículo científico publicado en 2011

Effects of tocilizumab on neutrophil function and kinetics

artículo científico publicado en 2017

Efficacy and tolerability of anti-immunoglobulin E therapy with omalizumab in patients with poorly controlled (moderate-to-severe) allergic asthma.

artículo científico publicado en 2004

Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus

scientific article published on 09 March 2022

Eotaxin-1/CC chemokine ligand 11: a novel eosinophil survival factor secreted by human pulmonary artery endothelial cells

artículo científico publicado en 2007

Epidermal deletion of HIF-2α stimulates wound closure

artículo científico publicado en 2013

Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity

artículo científico publicado en 2017

Evasion of Neutrophil Extracellular Traps by Respiratory Pathogens

artículo científico publicado en 2016

Exposure of patients to ionising radiation during lung cancer diagnostic work-up

artículo científico publicado en 2017

Fat embolism syndrome with Purtscher's retinopathy

artículo científico publicado en 2013

Formation of inositol polyphosphates in airway smooth muscle after muscarinic receptor stimulation

artículo científico publicado en 1990

Functional redundancy of class I phosphoinositide 3-kinase (PI3K) isoforms in signaling growth factor-mediated human neutrophil survival

artículo científico publicado en 2012

Future treatment in patients with chronic obstructive pulmonary disease: to reverse or not to reverse steroid resistance-that is the question

artículo científico publicado en 2014

Gbetagammas and the Ras binding domain of p110gamma are both important regulators of PI(3)Kgamma signalling in neutrophils

artículo científico publicado en 2006

Genome-wide transcription profiling in neutrophils in acute respiratory distress syndrome

artículo científico publicado en 2015

Granulocyte/macrophage colony-stimulating factor causes a paradoxical increase in the BH3-only pro-apoptotic protein Bim in human neutrophils

artículo científico publicado en 2010

HIF isoforms in the skin differentially regulate systemic arterial pressure

artículo científico publicado en 2013

HIF2α-arginase axis is essential for the development of pulmonary hypertension.

artículo científico publicado en 2016

How receptors work: mechanisms of signal transduction.

artículo científico publicado en 1994

Human Cytomegalovirus Delays Neutrophil Apoptosis and Stimulates the Release of a Prosurvival Secretome

artículo científico publicado en 2017

Hypoxia causes IL-8 secretion, Charcot Leyden crystal formation, and suppression of corticosteroid-induced apoptosis in human eosinophils.

artículo científico publicado en 2016

Hypoxia determines survival outcomes of bacterial infection through HIF-1alpha dependent re-programming of leukocyte metabolism

artículo científico publicado en 2017

Hypoxia prolongs neutrophil survival in vitro

artículo científico publicado en 1995

Hypoxia selectively inhibits respiratory burst activity and killing of Staphylococcus aureus in human neutrophils.

artículo científico publicado en 2010

Hypoxia upregulates neutrophil degranulation and potential for tissue injury

artículo científico publicado en 2016

Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity

artículo científico publicado en 2005

Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish.

artículo científico publicado en 2013

Hypoxia. Hypoxia, hypoxia inducible factor and myeloid cell function

scientific article published on 21 April 2009

Hypoxic regulation of neutrophil function and consequences for Staphylococcus aureus infection.

artículo científico publicado en 2016

Identification of LukPQ, a novel, equid-adapted leukocidin of Staphylococcus aureus

artículo científico publicado en 2017

Idiopathic pulmonary fibrosis in a Christmas Island nuclear test veteran ⬇️

artículo científico publicado el 23 de noviembre de 2010

Incidence and recognition of acute respiratory distress syndrome in a UK intensive care unit

artículo científico publicado en 2016

Induction of human neutrophil apoptosis by nitric oxide donors: evidence for a caspase-dependent, cyclic-GMP-independent, mechanism

artículo científico publicado en 2000

Inhibition of neuropeptide-stimulated tyrosine phosphorylation and tyrosine kinase activity stimulates apoptosis in small cell lung cancer cells.

artículo científico publicado en 1996

Inositol phosphates and airway smooth muscle.

artículo científico

Interleukin-10 does not directly affect the constitutive rate of human neutrophil or eosinophil apoptosis

scientific article published on 01 May 1997

Interleukin-5 inhibits glucocorticoid-mediated apoptosis in human eosinophils

artículo científico publicado en 2010

Interstitial pneumonitis and anti-tumor necrosis factor-alpha therapy

artículo científico publicado en 2007

Involvement of a ferroprotein sensor in hypoxia-mediated inhibition of neutrophil apoptosis

artículo científico publicado en 2002

Involvement of mitogen-activated protein kinase homologues in the regulation of lipopolysaccharide-mediated induction of cyclo-oxygenase-2 but not nitric oxide synthase in RAW 264.7 macrophages.

artículo científico publicado en 1999

Kinetics of pulmonary neutrophil recruitment and clearance in a natural and spontaneously resolving model of airway inflammation.

artículo científico publicado en 2005

Lack of effect of recombinant platelet-derived growth factor on human neutrophil function.

artículo científico

Lack of effect of zaprinast on methacholine-induced contraction and inositol 1,4,5-trisphosphate accumulation in bovine tracheal smooth muscle ⬇️

artículo científico publicado el 1 de mayo de 1991

Lesson of the month: novel method to quantify neutrophil uptake in early lung cancer using SPECT-CT

scientific article published on 04 September 2020

Live and let die: is neutrophil apoptosis defective in severe asthma?

artículo científico publicado en 2010

Mathematical modeling supports the presence of neutrophil depriming in vivo

artículo científico publicado en 2014

Measurement of Eosinophil Kinetics in Healthy Volunteers

artículo científico publicado en 2014

Measuring whole-body neutrophil redistribution using a dedicated whole-body counter and ultra-low doses of 111Indium

artículo científico publicado en 2010

Mechanical deformation induces depolarization of neutrophils

artículo científico publicado en 2017

Mechanics meets medicine

artículo científico publicado en 2013

Mechanism of accumulation of 99mTc-sulesomab in inflammation

scientific article published on 01 January 2003

Mechanotransduction in neutrophil activation and deactivation

artículo científico

Medical training in the UK: sleepwalking to disaster

artículo científico publicado en 2007

Miliary tuberculosis in edinburgh—A comparison between 1984–1992 and 1954–1967

artículo científico publicado en 1994

Modernising Medical Careers, Medical Training Application Service, and the Postgraduate Medical Education and Training Board: time for the emperors to don their clothes

artículo científico publicado en 2007

NBEAL2 is required for neutrophil and NK cell function and pathogen defense

artículo científico publicado en 2017

NF-κB Activation Is a Critical Regulator of Human Granulocyte Apoptosisin Vitro

artículo científico publicado en 1999

Neutrophil kinetics in health and disease.

artículo científico publicado en 2010

Neutrophil priming: pathophysiological consequences and underlying mechanisms.

artículo científico publicado en 1998

Neutrophil-mediated IL-6 receptor trans-signaling and the risk of chronic obstructive pulmonary disease and asthma

artículo científico publicado en 2017

Neutrophils from patients with heterozygous germline mutations in the von Hippel Lindau protein (pVHL) display delayed apoptosis and enhanced bacterial phagocytosis

artículo científico publicado en 2006

Non-infectious pulmonary complications of newer biological agents for rheumatic diseases--a systematic literature review

artículo científico publicado en 2011

Non-infectious pulmonary toxicity of rituximab: a systematic review

artículo científico publicado en 2011

Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury.

artículo científico publicado en 2018

Pharmacological manipulation of granulocyte apoptosis: potential therapeutic targets.

artículo científico publicado en 1999

Phosphatidylinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation.

artículo científico publicado en 1999

Phosphatidylinositol 3-phosphate is generated in phagosomal membranes.

artículo científico publicado en 2001

Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage

artículo científico publicado en 2013

Phosphoinositide metabolism in airway smooth muscle.

artículo científico publicado en 1994

Physiologic granulocyte destruction in vivo by apoptosis.

artículo científico publicado en 2004

Platelet-Derived Growth Factor-BB and Thrombin Activate Phosphoinositide 3-Kinase and Protein Kinase B: Role in Mediating Airway Smooth Muscle Proliferation

artículo científico publicado en 1998

Pleural disease--diagnosis and management.

artículo científico publicado en 1999

Polymers of alpha(1)-antitrypsin are chemotactic for human neutrophils: a new paradigm for the pathogenesis of emphysema

artículo científico publicado en 2002

Postprandial Glycaemic Effects of a Long-Acting Somatostatin Analogue (Octreotide) in Non-Insulin Dependent Diabetes Mellitus

artículo científico publicado en 1988

Priming and de-priming of neutrophil responses in vitro and in vivo

article

Priming differentially regulates neutrophil adhesion molecule expression/function

artículo científico publicado en 1996

Priming induces functional coupling of N -formyl-methionyl-leucyl-phenylalanine receptors in equine neutrophils

article

Priming of human neutrophil superoxide generation by tumour necrosis factor-alpha is signalled by enhanced phosphatidylinositol 3,4,5-trisphosphate but not inositol 1,4,5-trisphosphate accumulation.

artículo científico publicado en 1998

Prolonged survival of neutrophils from patients with F508 CFTR mutations

scientific article published on 01 July 2008

Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses

artículo científico

Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice

artículo científico publicado en 2011

Proteolytic action of duodenase is required to induce DNA synthesis in pulmonary artery fibroblasts

artículo científico publicado en 2002

Pulmonary Thromboemboli Modifying the Natural History of Pulmonary Arteriovenous Malformations

artículo científico publicado en 2011

Pulmonary complications of infliximab therapy in patients with rheumatoid arthritis

artículo científico publicado en 2006

Pulmonary elimination rate of inhaled 99mTc-sestamibi radioaerosol is delayed in healthy cigarette smokers

artículo científico publicado en 2008

Pulmonary retention of primed neutrophils: a novel protective host response, which is impaired in the acute respiratory distress syndrome

artículo científico publicado en 2014

Quantification of Lung PET Images: Challenges and Opportunities

artículo científico publicado en 2017

Quantification of disease activity in patients undergoing leucocyte scintigraphy for suspected inflammatory bowel disease

artículo científico publicado en 2004

Quantification of neutrophil migration into the lungs of patients with chronic obstructive pulmonary disease.

artículo científico publicado en 2011

Quantification of right to left shunt at rest and during exercise in patients with pulmonary arteriovenous malformations ⬇️

artículo científico publicado el 1 de octubre de 1992

Quantification of right to left shunt through pulmonary arteriovenous malformations using 99Tcm albumin microspheres

scientific article published on 01 November 1988

Rapid desensitization of GnRH-stimulated intracellular signalling events in alpha T3-1 and HEK-293 cells expressing the GnRH receptor ⬇️

artículo científico publicado el 1 de noviembre de 1995

Real-time deformability cytometry reveals sequential contraction and expansion during neutrophil priming

article

Regulation of granulocyte apoptosis and implications for anti-inflammatory therapy ⬇️

artículo científico publicado el 1 de julio de 1998

Regulation of macrophage phagocytosis of apoptotic cells by cAMP

artículo científico publicado en 1998

Regulation of neutrophil apoptosis by tumor necrosis factor-alpha: requirement for TNFR55 and TNFR75 for induction of apoptosis in vitro

artículo científico publicado en 1997

Regulation of phosphatidylinositol 3-kinase activity and phosphatidylinositol 3,4,5-trisphosphate accumulation by neutrophil priming agents

artículo científico publicado en 2002

RhoG regulates the neutrophil NADPH oxidase

artículo científico publicado en 2006

Role of PI3-kinase-dependent Bad phosphorylation and altered transcription in cytokine-mediated neutrophil survival

artículo científico publicado en 2002

Role of leukotrienes in the regulation of human granulocyte behaviour: dissociation between agonist-induced activation and retardation of apoptosis

artículo científico publicado en 2003

Role of neutrophil apoptosis in the resolution of pulmonary inflammation.

artículo científico publicado en 1999

Sarcoid-like granulomatous disease following etanercept treatment for RA

artículo científico publicado en 2007

Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils

artículo científico publicado en 2005

Severe Colitis Associated with Pirfenidone Use in Idiopathic Pulmonary Fibrosis

artículo científico publicado en 2016

Sphingosine kinase: a point of convergence in the action of diverse neutrophil priming agents

artículo científico publicado en 2002

Spontaneous rupture of an intercostal artery aneurysm during air flight.

artículo científico publicado en 2008

TARM1 Is a Novel Leukocyte Receptor Complex-Encoded ITAM Receptor That Costimulates Proinflammatory Cytokine Secretion by Macrophages and Neutrophils

artículo científico publicado en 2015

The Aminopeptidase CD13 Induces Homotypic Aggregation in Neutrophils and Impairs Collagen Invasion

artículo científico publicado en 2016

The Efficacy and Mechanism Evaluation of Treating Idiopathic Pulmonary fibrosis with the Addition of Co-trimoxazole (EME-TIPAC): study protocol for a randomised controlled trial.

artículo científico publicado en 2018

The HIF/VHL pathway: from oxygen sensing to innate immunity

artículo científico publicado en 2007

The blood supply of the islets of Langerhans in the Mongolian gerbil.

artículo científico publicado en 1983

The function and fate of neutrophils at the inflamed site: prospects for therapeutic intervention

artículo científico publicado en 2000

The presence of a constitutively active phosphoinositide 3-kinase in small cell lung cancer cells mediates anchorage-independent proliferation via a protein kinase B and p70s6k-dependent pathway.

artículo científico publicado en 1998

The role of HIF-1alpha in myeloid cell inflammation

artículo científico publicado en 2005

The serpinopathies studying serpin polymerization in vivo

artículo científico publicado en 2011

The survival effect of TNF-alpha in human neutrophils is mediated via NF-kappa B-dependent IL-8 release

artículo científico publicado en 2004

Thrombin induces DNA synthesis and phosphoinositide hydrolysis in airway smooth muscle by activation of distinct receptors

artículo científico publicado en 2005

Time to extend ‘the timetable of tuberculosis’?

artículo científico publicado en 1994

Transforming Growth Factor-β increases the inhibitory effects of GM-CSF and dexamethasone on neutrophil apoptosis

artículo científico publicado en 1997

Treating idiopathic pulmonary fibrosis with the addition of co-trimoxazole: a randomised controlled trial

artículo científico publicado en 2012

Treating idiopathic pulmonary fibrosis with the addition of co-trimoxazole: an economic evaluation alongside a randomised controlled trial

artículo científico publicado en 2014

Use of 111-Indium-labeled autologous eosinophils to establish the in vivo kinetics of human eosinophils in healthy subjects

artículo científico publicado en 2012

Use of 18FDG-pet to discriminate between infection and rejection in lung transplant recipients

artículo científico publicado en 2004

Use of technetium-99m-labeled eosinophils to detect active eosinophilic inflammation in humans.

artículo científico publicado en 2013

Viscoelastic properties of differentiating blood cells are fate- and function-dependent

artículo científico publicado en 2012

What can we learn from highly purified neutrophils?

artículo científico publicado en 2004

Wortmannin enhances tumour necrosis factorα-stimulated neutrophil apoptosis

artículo científico publicado en 1996

Zero G in a patient with advanced amyotrophic lateral sclerosis

scientific article published in The Lancet

[3H]inositol polyphosphate metabolism in muscarinic cholinoceptor-stimulated airways smooth muscle: accumulation of [3H]inositol 4,5 bisphosphate via a lithium-sensitive inositol polyphosphate 1-phosphatase

artículo científico publicado en 1997

z-VAD-fmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species

artículo científico publicado en 2004

β-adrenoceptor induced inhibition of muscarinic receptor-stimulated phosphoinositide metabolism is agonist specific in bovine tracheal smooth muscle

artículo científico publicado en 1991

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