Lista de obras - Sina A Gharib - Dominio Público Uruguay

A macrophage sterol-responsive network linked to atherogenesis

artículo científico publicado en 2010

A pathway-based analysis on the effects of obstructive sleep apnea in modulating visceral fat transcriptome.

artículo científico publicado en 2013

A systematic analysis of protein-altering exonic variants in chronic obstructive pulmonary disease

ADAM19 and HTR4 variants and pulmonary function: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

artículo científico publicado en 2014

Acute cellular rejection elicits distinct microRNA signatures in airway epithelium of lung transplant patients.

artículo científico publicado en 2015

Admixture mapping identifies novel loci for obstructive sleep apnea in hispanic/latino americans

scientific article published on 01 February 2019

Alveolar Macrophage Transcriptional Programs Are Associated with Outcomes in Acute Respiratory Distress Syndrome

artículo científico publicado en 2019

Association of 25-Hydroxyvitamin D status and genetic variation in the vitamin D metabolic pathway with FEV1 in the Framingham Heart Study

artículo científico publicado en 2015

Association of genetic loci with sleep apnea in European Americans and African-Americans: the Candidate Gene Association Resource (CARe).

artículo científico publicado en 2012

Association of sleep characteristics with atrial fibrillation: the Multi-Ethnic Study of Atherosclerosis

artículo científico publicado en 2015

Associations of variants In the hexokinase 1 and interleukin 18 receptor regions with oxyhemoglobin saturation during sleep

artículo científico publicado en 2019

Bridging the gap: merging clinical and inflammatory phenotypes with epithelial gene expression profiles in asthma

artículo científico publicado en 2014

COPD disease severity and innate immune response to pathogen-associated molecular patterns

artículo científico publicado en 2016

CYP2J2 expression in adult ventricular myocytes protects against external and drug induced ROS toxicity

artículo científico publicado en 2018

Cell type-specific immune dysregulation in severely ill COVID-19 patients

artículo científico publicado en 2020

Cell-specific image-guided transcriptomics identifies complex injuries caused by ischemic acute kidney injury in mice

scientific article published on 02 September 2019

Charting the transcriptional landscape of cells of renin lineage following podocyte depletion

artículo científico publicado en 2017

Cholesterol accumulation regulates expression of macrophage proteins implicated in proteolysis and complement activation

artículo científico publicado en 2012

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

artículo científico publicado en 2010

Common variants in DRD2 are associated with sleep duration: the CARe consortium

artículo científico publicado en 2015

Comparative evaluation of miRNA expression between in vitro and in vivo airway epithelium demonstrates widespread differences.

artículo científico publicado en 2013

Comparison of statistical data models for identifying differentially expressed genes using a generalized likelihood ratio test.

artículo científico publicado en 2008

Computational identification of key biological modules and transcription factors in acute lung injury.

artículo científico

Cytometry TOF identifies alveolar macrophage subtypes in acute respiratory distress syndrome.

artículo científico publicado en 2018

Distinct patterns of transcriptional and epigenetic alterations characterize acute and chronic kidney injury

scientific article published in Scientific Reports

Enzymatic and free radical formation of cis- and trans- epoxyeicosatrienoic acids in vitro and in vivo

artículo científico publicado en 2017

Epigenetic Signatures of Cigarette Smoking

artículo científico publicado en 2016

Epigenome-wide association analysis of daytime sleepiness in the Multi-Ethnic Study of Atherosclerosis reveals African-American-specific associations

scientific article published on 01 August 2019

Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.

artículo científico publicado en 2017

Experimental acute lung injury induces multi-organ epigenetic modifications in key angiogenic genes implicated in sepsis-associated endothelial dysfunction

artículo científico publicado en 2015

Exploration of the normal human bronchoalveolar lavage fluid proteome ⬇️

artículo científico publicado el 1 de abril de 2008

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

artículo científico publicado en 2019

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

artículo científico publicado en 2017

Genetic variability of smoking persistence in African Americans

artículo científico publicado en 2011

Genetic variants in RBFOX3 are associated with sleep latency

artículo científico publicado en 2016

Genome-wide association analysis identifies six new loci associated with forced vital capacity

artículo científico publicado en 2014

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

artículo científico publicado en 2011

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction

artículo científico publicado en 2012

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function

artículo científico publicado en 2012

Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants

artículo científico publicado en 2014

Heterogeneity of epigenetic changes at ischemia/reperfusion- and endotoxin-induced acute kidney injury genes.

artículo científico publicado en 2015

Impact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology.

artículo científico publicado en 2016

Individual matrix metalloproteinases control distinct transcriptional responses in airway epithelial cells infected with Pseudomonas aeruginosa.

artículo científico publicado en 2007

Induced sputum proteome in healthy subjects and asthmatic patients

artículo científico publicado en 2011

Integrative miRNA-mRNA profiling of adipose tissue unravels transcriptional circuits induced by sleep fragmentation

artículo científico publicado en 2012

Integrative pathway genomics of lung function and airflow obstruction

artículo científico publicado en 2015

Interleukin-17A Is Associated With Alveolar Inflammation and Poor Outcomes in Acute Respiratory Distress Syndrome

artículo científico publicado en 2015

Intermittent hypoxia activates temporally coordinated transcriptional programs in visceral adipose tissue

artículo científico publicado en 2011

Intermittent hypoxia mobilizes bone marrow-derived very small embryonic-like stem cells and activates developmental transcriptional programs in mice

artículo científico publicado en 2010

Large Meta-Analysis in the CHARGE Consortium Provides Evidence For an Association of Serum Vitamin D With Pulmonary Function

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function ⬇️

artículo científico publicado en 2014

Lipidomics reveals dramatic lipid compositional changes in the maturing postnatal lung

artículo científico publicado en 2017

Lung Pericytes and Resident Fibroblasts: Busy Multitaskers.

artículo científico publicado en 2016

Mapping the lung proteome in cystic fibrosis.

artículo científico

Matrix Metalloproteinase-28 Is a Key Contributor to Emphysema Pathogenesis.

artículo científico publicado en 2017

Matrix metalloproteinase-7 coordinates airway epithelial injury response and differentiation of ciliated cells

artículo científico publicado en 2012

Matrix metalloproteinases in emphysema.

artículo científico publicado en 2018

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

artículo científico publicado en 2010

Meta-analysis across Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium provides evidence for an association of serum vitamin D with pulmonary function

artículo científico publicado en 2018

Meta-analysis of exome array data identifies six novel genetic loci for lung function

scientific article published on 12 January 2018

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Molecular mechanisms underlying variations in lung function: a systems genetics analysis

artículo científico publicado en 2015

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

article

Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

artículo científico publicado en 2019

Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.

artículo científico publicado en 2017

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

artículo científico publicado en 2017

Multiethnic Meta-analysis Identifies New Loci for Pulmonary Function

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

scientific article published in Nature Communications

Noninjurious mechanical ventilation activates a proinflammatory transcriptional program in the lung

scientific article published on 10 March 2009

Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study

artículo científico publicado en 2014

Obstructive sleep apnea and cpap therapy alter distinct transcriptional programs in subcutaneous fat tissue

artículo científico publicado en 2019

Of mice and men: comparative proteomics of bronchoalveolar fluid.

artículo científico publicado en 2009

Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10-Pulmonary Function Association

artículo científico publicado en 2019

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

artículo científico publicado en 2018

Parasite burden and CD36-mediated sequestration are determinants of acute lung injury in an experimental malaria model.

artículo científico publicado en 2008

Pentraxin-2 suppresses c-Jun/AP-1 signaling to inhibit progressive fibrotic disease.

artículo científico publicado en 2016

Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury.

artículo científico publicado en 2012

Peripheral and Alveolar Cell Transcriptional Programs are Distinct in Acute Respiratory Distress Syndrome.

artículo científico publicado en 2017

Peripheral blood leukocyte gene expression patterns and metabolic parameters in habitually snoring and non-snoring children with normal polysomnographic findings.

artículo científico publicado en 2011

Plasticity of airway epithelial cell transcriptome in response to flagellin

artículo científico publicado en 2015

Prediction of mechanical properties of human atherosclerotic tissue by high-frequency intravascular ultrasound imaging. An in vitro study ⬇️

artículo científico publicado el 1 de enero de 1992

Proteomic and computational analysis of bronchoalveolar proteins during the course of the acute respiratory distress syndrome

artículo científico publicado en 2008

Proteomic landscape of bronchoalveolar lavage fluid in human immunodeficiency virus infection

artículo científico publicado en 2013

Proteomic profiling of bronchoalveolar lavage fluid in critically ill patients with ventilator-associated pneumonia

artículo científico publicado en 2013

Reply to Walter and Reyfman: Transcriptomic Analysis of Alveolar Immune Cells in Acute Respiratory Distress Syndrome: To Lump or to Split?

scientific article published on 01 November 2019

Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis.

scientific article published on October 2013

SYSTEM-WIDE MAPPING OF ACTIVATED CIRCUITRY IN EXPERIMENTAL SYSTEMIC INFLAMMATORY RESPONSE SYNDROME.

artículo científico publicado en 2015

Sample processing and single cell RNA-sequencing of peripheral blood immune cells from COVID-19 patients

artículo científico publicado en 2021

Sarcoidosis activates diverse transcriptional programs in bronchoalveolar lavage cells.

artículo científico publicado en 2016

Sequencing Analysis at 8p23 Identifies Multiple Rare Variants in DLC1 Associated with Sleep-Related Oxyhemoglobin Saturation Level

scientific article published on 24 October 2019

Sex differences in transcriptomic profiles in aged kidney cells of renin lineage.

artículo científico publicado en 2018

Shotgun MS proteomic analysis of bronchoalveolar lavage fluid in normal subjects

artículo científico publicado en 2014

Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL

artículo científico publicado en 2007

Sleep duration does not mediate or modify association of common genetic variants with type 2 diabetes

artículo científico publicado en 2013

Stromelysin-2 (MMP10) Moderates Inflammation by Controlling Macrophage Activation.

artículo científico publicado en 2016

Symptom profiles and inflammatory markers in moderate to severe COPD.

artículo científico publicado en 2016

Syndecan-1 controls lung tumorigenesis by regulating microRNAs packaged in exosomes

artículo científico publicado en 2018

Syndecan-1 promotes lung fibrosis by regulating epithelial reprogramming through extracellular vesicles

scientific article published on 08 August 2019

Synthesis and characterization of a new fluorescent probe for measuring potassium.

artículo científico publicado en 1990

Systematic identification of trans eQTLs as putative drivers of known disease associations

artículo científico publicado en 2013

TLR-2/TLR-4 TREM-1 signaling pathway is dispensable in inflammatory myeloid cells during sterile kidney injury.

artículo científico publicado en 2013

The Effects of Genotype × Phenotype Interactions on Transcriptional Response to Silver Nanoparticle Toxicity in Organotypic Cultures of Murine Tracheal Epithelial Cells

artículo científico publicado en 2020

The transcriptional landscape of age in human peripheral blood

artículo científico publicado en 2015

Tissue inhibitor of metalloproteinases-3 moderates the proinflammatory status of macrophages.

artículo científico publicado en 2013

Transcriptional Signatures of Sleep Duration Discordance in Monozygotic Twins

artículo científico

Transcriptional Survey of Alveolar Macrophages in a Murine Model of Chronic Granulomatous Inflammation Reveals Common Themes with Human Sarcoidosis.

artículo científico publicado en 2017

Transcriptional and functional diversity of human macrophage repolarization

artículo científico publicado en 2018

Transcriptional landscape of bone marrow-derived very small embryonic-like stem cells during hypoxia

artículo científico publicado en 2011

Transcriptional landscape of glomerular parietal epithelial cells

artículo científico publicado en 2014

Transcriptional signatures in donor lungs from donation after cardiac death vs after brain death: a functional pathway analysis.

artículo científico publicado en 2010

Transcriptomic analysis identifies phosphatases as novel targets for adenotonsillar hypertrophy of pediatric obstructive sleep apnea

artículo científico publicado en 2010

Treatment of obstructive sleep apnea alters cancer-associated transcriptional signatures in circulating leukocytes.

scientific article published on April 2014

Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants

scientific article published on 14 October 2020

Widespread activation of immunity and pro-inflammatory programs in peripheral blood leukocytes of HIV-infected patients with impaired lung gas exchange

artículo científico publicado en 2016

miR-323a-3p regulates lung fibrosis by targeting multiple profibrotic pathways.

artículo científico publicado en 2016

Lista de obras de Sina A Gharib

A macrophage sterol-responsive network linked to atherogenesis

A pathway-based analysis on the effects of obstructive sleep apnea in modulating visceral fat transcriptome.

A systematic analysis of protein-altering exonic variants in chronic obstructive pulmonary disease

ADAM19 and HTR4 variants and pulmonary function: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study

Acute cellular rejection elicits distinct microRNA signatures in airway epithelium of lung transplant patients.

Admixture mapping identifies novel loci for obstructive sleep apnea in hispanic/latino americans

Alveolar Macrophage Transcriptional Programs Are Associated with Outcomes in Acute Respiratory Distress Syndrome

Association of 25-Hydroxyvitamin D status and genetic variation in the vitamin D metabolic pathway with FEV1 in the Framingham Heart Study

Association of genetic loci with sleep apnea in European Americans and African-Americans: the Candidate Gene Association Resource (CARe).

Association of sleep characteristics with atrial fibrillation: the Multi-Ethnic Study of Atherosclerosis

Associations of variants In the hexokinase 1 and interleukin 18 receptor regions with oxyhemoglobin saturation during sleep

Bridging the gap: merging clinical and inflammatory phenotypes with epithelial gene expression profiles in asthma

COPD disease severity and innate immune response to pathogen-associated molecular patterns

CYP2J2 expression in adult ventricular myocytes protects against external and drug induced ROS toxicity

Cell type-specific immune dysregulation in severely ill COVID-19 patients

Cell-specific image-guided transcriptomics identifies complex injuries caused by ischemic acute kidney injury in mice

Charting the transcriptional landscape of cells of renin lineage following podocyte depletion

Cholesterol accumulation regulates expression of macrophage proteins implicated in proteolysis and complement activation

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

Common variants in DRD2 are associated with sleep duration: the CARe consortium

Comparative evaluation of miRNA expression between in vitro and in vivo airway epithelium demonstrates widespread differences.

Comparison of statistical data models for identifying differentially expressed genes using a generalized likelihood ratio test.

Computational identification of key biological modules and transcription factors in acute lung injury.

Cytometry TOF identifies alveolar macrophage subtypes in acute respiratory distress syndrome.

Distinct patterns of transcriptional and epigenetic alterations characterize acute and chronic kidney injury

Enzymatic and free radical formation of cis- and trans- epoxyeicosatrienoic acids in vitro and in vivo

Epigenetic Signatures of Cigarette Smoking

Epigenome-wide association analysis of daytime sleepiness in the Multi-Ethnic Study of Atherosclerosis reveals African-American-specific associations

Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.

Experimental acute lung injury induces multi-organ epigenetic modifications in key angiogenic genes implicated in sepsis-associated endothelial dysfunction

Exploration of the normal human bronchoalveolar lavage fluid proteome ⬇️

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

Genetic variability of smoking persistence in African Americans

Genetic variants in RBFOX3 are associated with sleep latency

Genome-wide association analysis identifies six new loci associated with forced vital capacity

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

Genome-wide association meta-analysis of PR interval identifies 47 novel loci associated with atrial and atrioventricular electrical activity

Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function

Habitual sleep duration is associated with BMI and macronutrient intake and may be modified by CLOCK genetic variants

Heterogeneity of epigenetic changes at ischemia/reperfusion- and endotoxin-induced acute kidney injury genes.

Impact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology.

Individual matrix metalloproteinases control distinct transcriptional responses in airway epithelial cells infected with Pseudomonas aeruginosa.

Induced sputum proteome in healthy subjects and asthmatic patients

Integrative miRNA-mRNA profiling of adipose tissue unravels transcriptional circuits induced by sleep fragmentation

Integrative pathway genomics of lung function and airflow obstruction

Interleukin-17A Is Associated With Alveolar Inflammation and Poor Outcomes in Acute Respiratory Distress Syndrome

Intermittent hypoxia activates temporally coordinated transcriptional programs in visceral adipose tissue

Intermittent hypoxia mobilizes bone marrow-derived very small embryonic-like stem cells and activates developmental transcriptional programs in mice

Large Meta-Analysis in the CHARGE Consortium Provides Evidence For an Association of Serum Vitamin D With Pulmonary Function

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function ⬇️

Lipidomics reveals dramatic lipid compositional changes in the maturing postnatal lung

Lung Pericytes and Resident Fibroblasts: Busy Multitaskers.

Mapping the lung proteome in cystic fibrosis.

Matrix Metalloproteinase-28 Is a Key Contributor to Emphysema Pathogenesis.

Matrix metalloproteinase-7 coordinates airway epithelial injury response and differentiation of ciliated cells

Matrix metalloproteinases in emphysema.

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

Meta-analysis across Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium provides evidence for an association of serum vitamin D with pulmonary function

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Molecular mechanisms underlying variations in lung function: a systems genetics analysis

Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids

Multi-ancestry sleep-by-SNP interaction analysis in 126,926 individuals reveals lipid loci stratified by sleep duration

Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men.

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Multiethnic Meta-analysis Identifies New Loci for Pulmonary Function

Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

Noninjurious mechanical ventilation activates a proinflammatory transcriptional program in the lung

Novel loci associated with usual sleep duration: the CHARGE Consortium Genome-Wide Association Study

Obstructive sleep apnea and cpap therapy alter distinct transcriptional programs in subcutaneous fat tissue

Of mice and men: comparative proteomics of bronchoalveolar fluid.

Omega-3 Fatty Acids and Genome-Wide Interaction Analyses Reveal DPP10-Pulmonary Function Association

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

Parasite burden and CD36-mediated sequestration are determinants of acute lung injury in an experimental malaria model.

Pentraxin-2 suppresses c-Jun/AP-1 signaling to inhibit progressive fibrotic disease.

Pericyte TIMP3 and ADAMTS1 modulate vascular stability after kidney injury.

Peripheral and Alveolar Cell Transcriptional Programs are Distinct in Acute Respiratory Distress Syndrome.