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Lista de obras de Juan Carlos Roa

AKT/mTOR substrate P70S6K is frequently phosphorylated in gallbladder cancer tissue and cell lines

artículo científico publicado en 2013

Angiotensin-(1-9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway

scientific article published on 09 March 2020

Beneficial effects of mineralocorticoid receptor blockade in experimental non-alcoholic steatohepatitis.

artículo científico publicado en 2015

CMS: a web-based system for visualization and analysis of genome-wide methylation data of human cancers

artículo científico publicado en 2013

Calcium calmodulin dependent kinase kinase 2 - a novel therapeutic target for gastric adenocarcinoma

artículo científico publicado en 2015

Canonical ErbB-2 isoform and ErbB-2 variant c located in the nucleus drive triple negative breast cancer growth

artículo científico publicado en 2020

Cellular FLICE-like Inhibitory Protein Long Form (c-FLIPL) Overexpression is Related to Cervical Cancer Progression ⬇️

artículo científico publicado el 1 de mayo de 2013

Circulating Levels of Inflammatory Proteins and Survival in Patients with Gallbladder Cancer

artículo científico publicado en 2018

Circulating MicroRNAs as Biomarkers in Biliary Tract Cancers

artículo científico publicado en 2016

Clinical and public health research using methylated DNA immunoprecipitation (MeDIP): a comparison of commercially available kits to examine differential DNA methylation across the genome

artículo científico publicado en 2012

Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer.

artículo científico publicado en 2012

Complete pathological response to Imatinib mesylate in an extraintestinal gastrointestinal stromal tumor

artículo científico publicado en 2014

Concordance between Gleason scores of trans rectal biopsies and the surgical piece of radical prostatectomy

artículo científico publicado el 11 de julio de 2011

Connective tissue growth factor immunohistochemical expression is associated with gallbladder cancer progression.

artículo científico publicado en 2013

Criteria for Pathologic Sampling of Gallbladder Specimens

scientific article published on 01 August 2013

Current and New Biomarkers for Early Detection, Prognostic Stratification, and Management of Gallbladder Cancer Patients

scientific article published on 07 December 2020

DNA promoter methylation as a diagnostic and therapeutic biomarker in gallbladder cancer ⬇️

artículo científico publicado el 13 de julio de 2012

Description of Echinococcus granulosus genotypes in human hydatidosis in a region of southern Chile

artículo científico publicado en 2008

Differential expression profile of CXCR3 splicing variants is associated with thyroid neoplasia. Potential role in papillary thyroid carcinoma oncogenesis?

artículo científico publicado en 2017

Duodenal villous atrophy associated with Mycophenolate mofetil: report of one case

artículo científico publicado el 12 de julio de 2010

Early gallbladder carcinoma has a favorable outcome but Rokitansky-Aschoff sinus involvement is an adverse prognostic factor.

artículo científico publicado en 2013

Emerging Role of miRNAs in the Drug Resistance of Gastric Cancer

artículo científico publicado en 2016

Eosinophilic Cholecystitis and Eosinophils in Gallbladder Injuries: A Clinicopathological Analysis of 1050 Cholecystectomies

artículo científico publicado en 2023

Evaluation of ZAR1 and SFRP4 methylation status as potentials biomarkers for diagnosis in cervical cancer: exploratory study phase I.

artículo científico publicado en 2014

Evaluation of the chemopreventive potentials of ezetimibe and aspirin in a novel mouse model of gallbladder preneoplasia

scientific article published on 17 September 2020

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

artículo científico publicado en 2013

Frequency of Chlamydia trachomatis infection in a group of women from Region of Araucanía, Chile

scientific article published on December 2013

Frequency of Human papillomavirus in women attending cervical cancer screening program in Chile

artículo científico

Functional and genomic characterization of three novel cell lines derived from a metastatic gallbladder cancer tumor

artículo científico publicado en 2020

Galectin-8 induces partial epithelial-mesenchymal transition with invasive tumorigenic capabilities involving a FAK/EGFR/proteasome pathway in MDCK cells.

artículo científico publicado en 2018

Gallbladder cancer: a morphological and molecular update.

artículo científico publicado en 2009

Gallbladder cancer: expert consensus statement.

artículo científico publicado en 2015

Genetic alterations in preneoplastic and neoplastic injuries of the gallbladder

artículo científico publicado el 12 de julio de 2010

Genetic methylation in carcinogenesis and its application in clinical oncology

artículo científico publicado en 2006

Genome-wide DNA methylation analysis reveals estrogen-mediated epigenetic repression of metallothionein-1 gene cluster in breast cancer

artículo científico publicado en 2015

Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population

artículo científico publicado en 2013

Genotyping of human papillomavirus in cervical intraepithelial neoplasia in a high-risk population

artículo científico publicado en 2011

Global phosphotyrosine survey in triple-negative breast cancer reveals activation of multiple tyrosine kinase signaling pathways

artículo científico publicado en 2015

HPV genotyping from invasive cervical cancer in Chile

artículo científico publicado en 2009

Helicobacter pylori: cagA analysis and vacA genotyping in Chile. Detection of a s2/m1 strain

artículo científico publicado el 1 de octubre de 2001

Heregulin Co-opts PR Transcriptional Action Via Stat3 Role As a Coregulator to Drive Cancer Growth

artículo científico publicado en 2015

Herpud1 negatively regulates pathological cardiac hypertrophy by inducing IP3 receptor degradation

artículo científico publicado en 2017

Hyalinizing cholecystitis and associated carcinomas: clinicopathologic analysis of a distinctive variant of cholecystitis with porcelain-like features and accompanying diagnostically challenging carcinomas

artículo científico publicado en 2011

Identification of prosaposin and transgelin as potential biomarkers for gallbladder cancer using quantitative proteomics.

artículo científico publicado en 2014

Immunohistochemical expression of phospho-mTOR is associated with poor prognosis in patients with gallbladder adenocarcinoma.

artículo científico publicado en 2013

Immunohistochemical expression of vascular endothelial growth factor A in advanced gallbladder carcinoma

artículo científico publicado en 2014

Inhibition of connective tissue growth factor (CTGF/CCN2) in gallbladder cancer cells leads to decreased growth in vitro.

artículo científico publicado en 2013

Intracholecystic papillary-tubular neoplasms (ICPN) of the gallbladder (neoplastic polyps, adenomas, and papillary neoplasms that are ≥1.0 cm): clinicopathologic and immunohistochemical analysis of 123 cases

artículo científico publicado en 2012

Invasive micropapillary carcinoma of the breast overexpresses MUC4 and is associated with poor outcome to adjuvant trastuzumab in HER2-positive breast cancer.

artículo científico publicado en 2017

Loss of Expression of Reprimo, a p53-induced Cell Cycle Arrest Gene, Correlates with Invasive Stage of Tumor Progression and p73 Expression in Gastric Cancer

artículo científico publicado en 2015

Low expression of equilibrative nucleoside transporter 1 is associated with poor prognosis in chemotherapy-naïve pT2 gallbladder adenocarcinoma patients.

artículo científico publicado en 2015

Macrophage migration inhibitory factor - a therapeutic target in gallbladder cancer.

artículo científico publicado en 2015

MiR-16 mediates trastuzumab and lapatinib response in ErbB-2-positive breast and gastric cancer via its novel targets CCNJ and FUBP1.

artículo científico publicado en 2016

MicroRNA-335-5p is a potential suppressor of metastasis and invasion in gastric cancer.

artículo científico publicado en 2017

Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy

artículo científico publicado en 2015

Mucin 5B, carbonic anhydrase 9 and claudin 18 are potential theranostic markers of gallbladder carcinoma

artículo científico publicado en 2019

Mucinous carcinomas of the gallbladder: clinicopathologic analysis of 15 cases identified in 606 carcinomas

artículo científico publicado en 2012

Neoadjuvant chemoradiation therapy for borderline pancreatic adenocarcinoma: report of two cases.

artículo científico publicado en 2013

Overexpression of Kinesin Associated Protein 3 (KIFAP3) in Breast Cancer

artículo científico publicado en 2012

Overexpression of ribosome binding protein 1 (RRBP1) in breast cancer.

artículo científico publicado en 2012

Pathologic Evaluation and Reporting of Intraductal Papillary Mucinous Neoplasms of the Pancreas and Other Tumoral Intraepithelial Neoplasms of Pancreatobiliary Tract: Recommendations of Verona Consensus Meeting

artículo científico publicado en 2015

Pathologic staging of pancreatic, ampullary, biliary, and gallbladder cancers: pitfalls and practical limitations of the current AJCC/UICC TNM staging system and opportunities for improvement.

artículo científico

Poorly cohesive cell (diffuse-infiltrative/signet ring cell) carcinomas of the gallbladder: clinicopathological analysis of 24 cases identified in 628 gallbladder carcinomas

artículo científico publicado en 2016

Primary hyperthyroidism after excision of a Struma ovarii

artículo científico publicado el 1 de julio de 2003

Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer growth and predicts response to endocrine therapy

artículo científico publicado en 2013

Prognostic factors for gastric cancer without lymph node involvement

artículo científico publicado el 25 de agosto de 2011

Promoter methylation profile in preneoplastic and neoplastic gallbladder lesions.

artículo científico publicado en 2009

Quantitative phosphoproteomic analysis of IL-33-mediated signaling

artículo científico

RNA sequencing-based analysis of gallbladder cancer reveals the importance of the liver X receptor and lipid metabolism in gallbladder cancer

artículo científico publicado en 2016

Rapamycin and WYE-354 suppress human gallbladder cancer xenografts in mice

artículo científico publicado en 2015

Reprimo as a modulator of cell migration and invasion in the MDA-MB-231 breast cancer cell line.

artículo científico publicado en 2016

Reprimo, a Potential p53-Dependent Tumor Suppressor Gene, Is Frequently Hypermethylated in Estrogen Receptor α-Positive Breast Cancer

artículo científico

SILAC-based quantitative proteomic analysis of gastric cancer secretome.

artículo científico publicado en 2013

Salmonella enterica serovar Typhi and gallbladder cancer: a case-control study and meta-analysis

scientific article published on 11 October 2016

Serial analysis of gene expression identifies connective tissue growth factor expression as a prognostic biomarker in gallbladder cancer

artículo científico publicado en 2008

Small molecule inhibitor screening identifified HSP90 inhibitor 17-AAG as potential therapeutic agent for gallbladder cancer.

artículo científico publicado en 2017

Squamous cell and adenosquamous carcinomas of the gallbladder: clinicopathological analysis of 34 cases identified in 606 carcinomas

artículo científico publicado en 2011

Stat3 regulates ErbB-2 expression and co-opts ErbB-2 nuclear function to induce miR-21 expression, PDCD4 downregulation and breast cancer metastasis.

artículo científico publicado en 2015

Study protocol for the Maule Cohort (MAUCO) of chronic diseases, Chile 2014-2024

artículo científico publicado en 2016

Synchronous ileocecal and duodenal tuberculosis: case report and review of the literature

scientific article published on 10 May 2014

TNFα-Induced Mucin 4 Expression Elicits Trastuzumab Resistance in HER2-Positive Breast Cancer

artículo científico publicado en 2016

Targeting ErbB-2 nuclear localization and function inhibits breast cancer growth and overcomes trastuzumab resistance.

artículo científico publicado en 2014

Targeting specific molecular pathways holds promise for advanced gallbladder cancer therapy.

artículo científico publicado en 2015

The Axl receptor tyrosine kinase is an adverse prognostic factor and a therapeutic target in esophageal adenocarcinoma

artículo científico publicado en 2010

The ERK/MAPK pathway is overexpressed and activated in gallbladder cancer.

artículo científico publicado en 2017

The Gene Expression Status of the PI3K/AKT/mTOR Pathway in Gastric Cancer Tissues and Cell Lines.

artículo científico publicado en 2016

The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance

artículo científico publicado en 2014

The inflammatory inception of gallbladder cancer

artículo científico publicado en 2016

Treatment of the residual cavity during hepatic hydatidosis surgery: a cohort study of capitonnage vs. omentoplasty

artículo científico publicado en 2013

Tumor lysate-based vaccines: on the road to immunotherapy for gallbladder cancer

artículo científico publicado en 2018

Virulence of infecting Helicobacter pylori strains and intensity of mononuclear cell infiltration are associated with levels of DNA hypermethylation in gastric mucosae

artículo científico publicado en 2013

Widespread Hypomethylation Occurs Early and Synergizes with Gene Amplification during Esophageal Carcinogenesis ⬇️

artículo científico publicado el 31 de marzo de 2011

[Recommendations for the management of pancreatic cancer type adenocarcinoma: A consensus statement reached during the 2015 Latin American Symposium on Gastroenterological Oncology]

artículo científico publicado en 2016

miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway

artículo científico publicado en 2015

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