Lista de obras - Kevin Morgan - Dominio Público Uruguay

A Fluorescence Resonance Energy Transfer Assay For Monitoring α- Synclein Aggregation in a Caenorhabditis Elegans Model For Parkinson's Disease

artículo científico publicado en 2015

A Passive Sodium Transport Inhibitory Factor (Inhibitin) Released from Leukaemic Promyelocytes in Culture

article

A SNP in the ACT gene associated with astrocytosis and rapid cognitive decline in AD.

artículo científico publicado en 2007

A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression

artículo científico publicado en 2016

A multi-center study of ACE and the risk of late-onset Alzheimer's disease

artículo científico publicado en 2011

A new promoter polymorphism in the alpha-1-antichymotrypsin gene is a disease modifier of Alzheimer's disease

artículo científico publicado en 2005

A polymorphism of the alpha1-antitrypsin gene represents a risk factor for liver disease

article

A rare loss-of-function variant of ADAM17 is associated with late-onset familial Alzheimer disease

artículo científico publicado en 2018

ABCA7 p.G215S as potential protective factor for Alzheimer's disease

artículo científico publicado en 2016

Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes

artículo científico publicado en 2013

Allele-specific overexpression in astrocytes of an Alzheimer's disease associated alpha-1-antichymotrypsin promoter polymorphism

artículo científico publicado en 2004

Alzheimer's disease polygenic risk score as a predictor of conversion from mild-cognitive impairment

artículo científico publicado en 2019

Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance to Alzheimer's disease

artículo científico publicado en 2003

An alpha1-antitrypsin enhancer polymorphism is a genetic modifier of pulmonary outcome in cystic fibrosis.

artículo científico publicado en 2001

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.

artículo científico publicado en 2016

Analysis of Genome-Wide Association Study (GWAS) data looking for replicating signals in Alzheimer's disease (AD).

artículo científico publicado en 2009

Analysis of shared heritability in common disorders of the brain

artículo científico publicado en 2018

ApoE variant p.V236E is associated with markedly reduced risk of Alzheimer's disease

artículo científico publicado en 2014

Association of MMP-2 polymorphisms with severe and very severe COPD: a case control study of MMPs-1, 9 and 12 in a European population

artículo científico publicado en 2010

Association of improved pulmonary phenotype in Irish cystic fibrosis patients with a 3' enhancer polymorphism in alpha-1-antitrypsin.

artículo científico publicado en 2006

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Blood type gene locus has no influence on ACE association with Alzheimer's disease

artículo científico publicado en 2015

Calcium retention and increased vascular reactivity caused by a hypothalamic sodium transport inhibitor ⬇️

artículo científico publicado el 1 de agosto de 1988

Characterization of Na+ transport in normal human fibroblasts and neoplastic H.Ep.2 cells and the role of inhibitin

scientific article published on 01 December 1988

Cognitive phenotypes in Alzheimer's disease and genetic variants in ACE and IDE.

artículo científico publicado en 2011

Commentary on Functional analysis of APOE Locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE

article

Common polygenic variation enhances risk prediction for Alzheimer's disease

artículo científico publicado en 2015

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

artículo científico publicado en 2011

Complement receptor 1 gene (CR1) intragenic duplication and risk of Alzheimer's disease.

artículo científico publicado en 2018

Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease

artículo científico publicado en 2010

Correction: Alzheimer's disease polygenic risk score as a predictor of conversion from mild-cognitive impairment.

artículo científico publicado en 2019

Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease

scholarly article published March 2006

Cryptic haplotypes ofSERPINA1confer susceptibility to chronic obstructive pulmonary disease

article

Cystic fibrosis, disease severity, and a macrophage migration inhibitory factor polymorphism

artículo científico publicado en 2005

Differential regulation of secretory leukocyte protease inhibitor and elafin by progesterone

artículo científico publicado en 2003

Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease.

artículo científico publicado en 2012

Effects of Alzheimer's peptide and α1-antichymotrypsin on astrocyte gene expression

article

Enzyme-Labelled Oligonucleotides for the Detection of 1-Antitrypsin Deficiency: Optimization of Enzyme Activity for Single Point Mutation Detection

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scholarly article published in Nature Genetics

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

article

Erythrocyte Sodium-Potassium-ATPase and Sodium Transport in Obesity

article by M. A. Mir et al published 19 November 1981 in The New England Journal of Medicine

Erythrocyte sodium pump activity in human obesity

artículo científico publicado en 1984

Evaluating pathogenic dementia variants in posterior cortical atrophy

artículo científico publicado en 2015

Evaluation of polymorphisms in the presenilin-1 gene and the butyrylcholinesterase gene as risk factors in sporadic Alzheimer's disease

article

Exome sequencing identifies 2 novel presenilin 1 mutations (p.L166V and p.S230R) in British early-onset Alzheimer's disease

artículo científico publicado en 2014

Gene expression levels as endophenotypes in genome-wide association studies of Alzheimer disease

artículo científico publicado en 2010

Gene regulation of the serine proteinase inhibitors alpha1-antitrypsin and alpha1-antichymotrypsin

artículo científico publicado en 2002

Gene regulation of the serine proteinase inhibitors α 1 -antitrypsin and α 1 -antichymotrypsin

artículo científico publicado en 2002

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

artículo científico publicado en 2014

Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies.

artículo científico publicado en 2014

Genetic differences in lithium-sodium exchange and regulation of the sodium-hydrogen exchanger in essential hypertension

article

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

artículo científico publicado en 2010

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

artículo científico publicado en 2019

Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS).

artículo científico publicado en 2012

Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD.

artículo científico publicado en 2008

Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

artículo científico publicado en 2021

Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases

artículo científico publicado en 2015

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

artículo científico publicado en 2009

Genotyping of the Alzheimer’s Disease Genome-Wide Association Study Index Single Nucleotide Polymorphisms in the Brains for Dementia Research Cohort

scholarly article by Keeley J. Brookes et al published 19 June 2018 in Journal of Alzheimer's Disease

Greater frequency of K-ras Val-12 mutation in colorectal cancer as detected with sensitive methods

artículo científico publicado en 1996

HLA class I, II & III genes in confirmed late-onset Alzheimer's disease

article

Haplotypes of the alpha-1 antitrypsin gene in healthy controls and Z deficiency patients.

artículo científico publicado en 2004

Identification of SPARC-like 1 protein as part of a biomarker panel for Alzheimer's disease in cerebrospinal fluid

artículo científico publicado en 2012

Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer's Disease

artículo científico publicado en 2016

Interaction of inhibitin with the human erythrocyte Na+(Li+)i/Nao+ exchanger

artículo científico publicado en 1989

Interaction of insulin and PPAR-α genes in Alzheimer's disease: the Epistasis Project.

artículo científico publicado en 2011

Interactions of external and internal H+ and Na+ with Na+/Na+ and Na+/H+ exchange of rabbit red cells: evidence for a common pathway

artículo científico publicado en 1990

Investigating statistical epistasis in complex disorders.

artículo científico publicado en 2011

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

artículo científico publicado en 2017

Investigating the role of rare coding variability in Mendelian dementia genes (APP, PSEN1, PSEN2, GRN, MAPT, and PRNP) in late-onset Alzheimer's disease

artículo científico publicado en 2014

Investigation of 15 of the top candidate genes for late-onset Alzheimer's disease

artículo científico publicado en 2011

Kinetic abnormalities of the red blood cell sodium-proton exchange in hypertensive patients

artículo científico publicado en 1991

Leukaemic promyelocytes and normal bone marrow cells release a passive sodium transport modifier (inhibitin)

scientific article published on 01 March 1985

Linking protective GAB2 variants, increased cortical GAB2 expression and decreased Alzheimer's disease pathology

artículo científico publicado en 2013

Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3.

artículo científico publicado en 2018

Missense variant in TREML2 protects against Alzheimer's disease

scientific article published on 21 December 2013

Multiple insulin degrading enzyme variants alter in vitro reporter gene expression

artículo científico publicado en 2011

Mutation analysis of sporadic early-onset Alzheimer's disease using the NeuroX array

artículo científico publicado en 2016

Mutation in an alpha1-antitrypsin enhancer results in an interleukin-6 deficient acute-phase response due to loss of cooperativity between transcription factors

artículo científico publicado en 1997

Na+/H+ exchange is increased in sickle cell anemia and young normal red cells

artículo científico publicado en 1990

Next generation sequencing of CLU, PICALM and CR1: pitfalls and potential solutions.

artículo científico publicado en 2012

No evidence that extended tracts of homozygosity are associated with Alzheimer's disease.

artículo científico publicado en 2011

Oncostatin M induced alpha1-antitrypsin (AAT) gene expression in Hep G2 cells is mediated by a 3' enhancer

artículo científico publicado en 2002

PSEN1 polymorphisms alter the rate of cognitive decline in sporadic Alzheimer's disease patients

scholarly article by Olivia Belbin et al published December 2009 in Neurobiology of Aging

Plasmonic-array-based biosensors for the diagnosis of neurodegenerative diseases

Polygenic risk score in postmortem diagnosed sporadic early-onset Alzheimer's disease

artículo científico publicado en 2017

Preincubation superior to strict competition with mismatched oligonucleotides for detecting alpha 1-antitrypsin deficiency

article

Prokineticin 1 modulates IL-8 expression via the calcineurin/NFAT signaling pathway

artículo científico publicado en 2009

Prokineticin 1 signaling and gene regulation in early human pregnancy

artículo científico publicado en 2008

Psychological stress, cognitive decline and the development of dementia in amnestic mild cognitive impairment

artículo científico publicado en 2020

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

artículo científico publicado en 2017

Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer's disease

artículo científico publicado en 2014

Rationalising the role of Keratin 9 as a biomarker for Alzheimer's disease

artículo científico publicado en 2016

Regulation of the α1-Antitrypsin Gene and a Disease-associated Mutation in a Related Enhancer Sequence

article

Regulatory region single nucleotide polymorphisms of the apolipoprotein E gene and the rate of cognitive decline in Alzheimer's disease.

artículo científico publicado en 2007

Replication by the Epistasis Project of the interaction between the genes for IL-6 and IL-10 in the risk of Alzheimer's disease

artículo científico publicado en 2009

Replication of BIN1 association with Alzheimer's disease and evaluation of genetic interactions

artículo científico publicado en 2011

Replication of CLU, CR1, and PICALM associations with alzheimer disease.

artículo científico publicado en 2010

Replication of EPHA1 and CD33 associations with late-onset Alzheimer's disease: a multi-centre case-control study

artículo científico publicado en 2011

Reverse engineering of Alzheimer's disease based on biomarker pathways analysis

artículo científico publicado en 2014

Review: The genetics of Alzheimer's disease; putting flesh on the bones

artículo científico

SERPINA3 (aka alpha-1-antichymotrypsin).

artículo científico publicado en 2007

Screening exons 16 and 17 of the amyloid precursor protein gene in sporadic early-onset Alzheimer's disease

artículo científico publicado en 2015

Serpins: structure, function and molecular evolution.

artículo científico publicado en 2003

Serum stimulation of sodium transport in human fibroblasts containing low and high levels of intracellular sodium

artículo científico publicado en 1986

Simple and efficient cDNA capture utilising a short gene-specific probe attached to magnetic beads

article

Sodium-Potassium-ATPase and Obesity

artículo científico publicado en 1984

TREM2 Variants in Alzheimer's Disease

artículo científico publicado en 2013

The SERPINE2 gene and chronic obstructive pulmonary disease.

artículo científico publicado en 2006

The alpha-1-antitrypsin gene promoter in human A549 lung derived cells, and a novel transcription initiation site

artículo científico publicado en 2008

The dopamine β-hydroxylase -1021C/T polymorphism is associated with the risk of Alzheimer's disease in the Epistasis Project

artículo científico publicado en 2010

The hydroxy-methyl-glutaryl CoA reductase promoter polymorphism is associated with Alzheimer's risk and cognitive deterioration

artículo científico publicado en 2007

The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study

artículo científico publicado en 2011

The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease

artículo científico publicado en 2012

The sex-specific associations of the aromatase gene with Alzheimer's disease and its interaction with IL10 in the Epistasis Project

artículo científico publicado en 2013

The three new pathways leading to Alzheimer's disease

scholarly article by Kevin Morgan published June 2011 in Neuropathology and Applied Neurobiology

Transcription termination and DNase I hypersensitive sites in the 3′ flanking sequence of the alpha-1-antitrypsin gene

article

Transferrin and HFE genes interact in Alzheimer's disease risk: the Epistasis Project

artículo científico publicado en 2010

Using In silico LD clumping and meta-analysis of genome-wide datasets as a complementary tool to investigate and validate new candidate biomarkers in Alzheimer's disease.

artículo científico publicado en 2010

Variation in the tumour necrosis factor gene is not associated with susceptibility to COPD

article

Vasoreactive effects of hypothalamic sodium transport inhibitor.

artículo científico publicado en 1988

Whole-exome sequencing of the BDR cohort: evidence to support the role of the PILRA gene in Alzheimer's disease.

artículo científico publicado en 2017

Lista de obras de Kevin Morgan

A Fluorescence Resonance Energy Transfer Assay For Monitoring α- Synclein Aggregation in a Caenorhabditis Elegans Model For Parkinson's Disease

A Passive Sodium Transport Inhibitory Factor (Inhibitin) Released from Leukaemic Promyelocytes in Culture

A SNP in the ACT gene associated with astrocytosis and rapid cognitive decline in AD.

A candidate regulatory variant at the TREM gene cluster associates with decreased Alzheimer's disease risk and increased TREML1 and TREM2 brain gene expression

A multi-center study of ACE and the risk of late-onset Alzheimer's disease

A new promoter polymorphism in the alpha-1-antichymotrypsin gene is a disease modifier of Alzheimer's disease

A polymorphism of the alpha1-antitrypsin gene represents a risk factor for liver disease

A rare loss-of-function variant of ADAM17 is associated with late-onset familial Alzheimer disease

ABCA7 p.G215S as potential protective factor for Alzheimer's disease

Allele-specific RNA interference rescues the long-QT syndrome phenotype in human-induced pluripotency stem cell cardiomyocytes

Allele-specific overexpression in astrocytes of an Alzheimer's disease associated alpha-1-antichymotrypsin promoter polymorphism

Alzheimer's disease polygenic risk score as a predictor of conversion from mild-cognitive impairment

Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance to Alzheimer's disease

An alpha1-antitrypsin enhancer polymorphism is a genetic modifier of pulmonary outcome in cystic fibrosis.

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.

Analysis of Genome-Wide Association Study (GWAS) data looking for replicating signals in Alzheimer's disease (AD).

Analysis of shared heritability in common disorders of the brain

ApoE variant p.V236E is associated with markedly reduced risk of Alzheimer's disease

Association of MMP-2 polymorphisms with severe and very severe COPD: a case control study of MMPs-1, 9 and 12 in a European population

Association of improved pulmonary phenotype in Irish cystic fibrosis patients with a 3' enhancer polymorphism in alpha-1-antitrypsin.

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Blood type gene locus has no influence on ACE association with Alzheimer's disease

Calcium retention and increased vascular reactivity caused by a hypothalamic sodium transport inhibitor ⬇️

Characterization of Na+ transport in normal human fibroblasts and neoplastic H.Ep.2 cells and the role of inhibitin

Cognitive phenotypes in Alzheimer's disease and genetic variants in ACE and IDE.

Commentary on Functional analysis of APOE Locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE

Common polygenic variation enhances risk prediction for Alzheimer's disease

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

Complement receptor 1 gene (CR1) intragenic duplication and risk of Alzheimer's disease.

Concordant association of insulin degrading enzyme gene (IDE) variants with IDE mRNA, Abeta, and Alzheimer's disease

Correction: Alzheimer's disease polygenic risk score as a predictor of conversion from mild-cognitive impairment.

Cryptic haplotypes of SERPINA1 confer susceptibility to chronic obstructive pulmonary disease

Cryptic haplotypes ofSERPINA1confer susceptibility to chronic obstructive pulmonary disease

Cystic fibrosis, disease severity, and a macrophage migration inhibitory factor polymorphism

Differential regulation of secretory leukocyte protease inhibitor and elafin by progesterone

Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease.

Effects of Alzheimer's peptide and α1-antichymotrypsin on astrocyte gene expression

Enzyme-Labelled Oligonucleotides for the Detection of 1-Antitrypsin Deficiency: Optimization of Enzyme Activity for Single Point Mutation Detection

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Erythrocyte Sodium-Potassium-ATPase and Sodium Transport in Obesity

Erythrocyte sodium pump activity in human obesity

Evaluating pathogenic dementia variants in posterior cortical atrophy

Evaluation of polymorphisms in the presenilin-1 gene and the butyrylcholinesterase gene as risk factors in sporadic Alzheimer's disease

Exome sequencing identifies 2 novel presenilin 1 mutations (p.L166V and p.S230R) in British early-onset Alzheimer's disease

Gene expression levels as endophenotypes in genome-wide association studies of Alzheimer disease

Gene regulation of the serine proteinase inhibitors alpha1-antitrypsin and alpha1-antichymotrypsin

Gene regulation of the serine proteinase inhibitors α 1 -antitrypsin and α 1 -antichymotrypsin

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease

Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies.

Genetic differences in lithium-sodium exchange and regulation of the sodium-hydrogen exchanger in essential hypertension

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS).

Genetic variants of microsomal epoxide hydrolase and glutamate-cysteine ligase in COPD.

Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture

Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Genotyping of the Alzheimer’s Disease Genome-Wide Association Study Index Single Nucleotide Polymorphisms in the Brains for Dementia Research Cohort

Greater frequency of K-ras Val-12 mutation in colorectal cancer as detected with sensitive methods

HLA class I, II & III genes in confirmed late-onset Alzheimer's disease

Haplotypes of the alpha-1 antitrypsin gene in healthy controls and Z deficiency patients.

Identification of SPARC-like 1 protein as part of a biomarker panel for Alzheimer's disease in cerebrospinal fluid

Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer's Disease

Interaction of inhibitin with the human erythrocyte Na+(Li+)i/Nao+ exchanger

Interaction of insulin and PPAR-α genes in Alzheimer's disease: the Epistasis Project.

Interactions of external and internal H+ and Na+ with Na+/Na+ and Na+/H+ exchange of rabbit red cells: evidence for a common pathway

Investigating statistical epistasis in complex disorders.

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

Investigating the role of rare coding variability in Mendelian dementia genes (APP, PSEN1, PSEN2, GRN, MAPT, and PRNP) in late-onset Alzheimer's disease

Investigation of 15 of the top candidate genes for late-onset Alzheimer's disease

Kinetic abnormalities of the red blood cell sodium-proton exchange in hypertensive patients

Leukaemic promyelocytes and normal bone marrow cells release a passive sodium transport modifier (inhibitin)

Linking protective GAB2 variants, increased cortical GAB2 expression and decreased Alzheimer's disease pathology

Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3.

Missense variant in TREML2 protects against Alzheimer's disease

Multiple insulin degrading enzyme variants alter in vitro reporter gene expression

Mutation analysis of sporadic early-onset Alzheimer's disease using the NeuroX array

Mutation in an alpha1-antitrypsin enhancer results in an interleukin-6 deficient acute-phase response due to loss of cooperativity between transcription factors