Lista de obras - Alessandro Moretta - Dominio Público Uruguay

Activating KIRs and NKG2C in Viral Infections: Toward NK Cell Memory?

artículo científico publicado en 2015

Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors

artículo científico publicado en 2011

Analysis of natural killer cells in TAP2-deficient patients: expression of functional triggering receptors and evidence for the existence of inhibitory receptor(s) that prevent lysis of normal autologous cells

artículo científico publicado en 2002

Analysis of natural killer cells isolated from human decidua: Evidence that 2B4 (CD244) functions as an inhibitory receptor and blocks NK-cell function.

artículo científico publicado en 2006

Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112)

artículo científico publicado en 2005

Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity

artículo científico publicado en 2008

B7-H6-mediated downregulation of NKp30 in NK cells contributes to ovarian carcinoma immune escape

artículo científico publicado en 2015

Both CD133+ and CD133- medulloblastoma cell lines express ligands for triggering NK receptors and are susceptible to NK-mediated cytotoxicity.

artículo científico publicado en 2007

Bridging innate NK cell functions with adaptive immunity.

artículo científico publicado en 2011

CD59 is physically and functionally associated with natural cytotoxicity receptors and activates human NK cell-mediated cytotoxicity

artículo científico publicado en 2003

Cellular ligands of activating NK receptors.

artículo científico publicado en 2005

Characterization of CD56-/CD16+ natural killer (NK) cells: a highly dysfunctional NK subset expanded in HIV-infected viremic individuals

artículo científico publicado en 2005

Characterization of the defective interaction between a subset of natural killer cells and dendritic cells in HIV-1 infection

artículo científico publicado en 2006

Cognate HLA absence in trans diminishes human NK cell education

scientific article published on 29 August 2016

Comparative analysis of human NK cell activation induced by NKG2D and natural cytotoxicity receptors

artículo científico publicado en 2004

Corrigendum: Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56bright NKG2A+++ Cells, and Yet Display Increased Degranulation and Higher Perforin Conten

artículo científico publicado en 2017

Crystallization and preliminary crystallographic characterization of the extracellular Ig-like domain of human natural killer cell activating receptor NKp44.

artículo científico publicado en 2002

DNAM-1 and PVR regulate monocyte migration through endothelial junctions

artículo científico publicado en 2004

Defective expression and function of natural killer cell-triggering receptors in patients with acute myeloid leukemia

artículo científico publicado en 2002

Dendritic cell editing by activated natural killer cells results in a more protective cancer-specific immune response

artículo científico publicado en 2012

Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation

artículo científico publicado en 2002

Early liaisons between cells of the innate immune system in inflamed peripheral tissues.

artículo científico publicado en 2005

Effector and regulatory events during natural killer-dendritic cell interactions

artículo científico publicado en 2006

Expression and crystallographic characterization of the extracellular domain of human natural killer cell triggering receptor NKp46.

artículo científico publicado en 2003

Expression and function of KIR and natural cytotoxicity receptors in NK-type lymphoproliferative diseases of granular lymphocytes.

artículo científico publicado en 2003

Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction

artículo científico publicado en 2006

Features of Memory-Like and PD-1(+) Human NK Cell Subsets

artículo científico publicado en 2016

Functional and molecular characterization of a KIR3DL2/p140 expressing tumor-specific cytotoxic T lymphocyte clone infiltrating a human lung carcinoma

artículo científico publicado en 2003

Functional characterization of natural killer cells in type I leukocyte adhesion deficiency

scientific article published on 01 February 2007

GPR56 as a novel marker identifying the CD56dull CD16+ NK cell subset both in blood stream and in inflamed peripheral tissues.

artículo científico publicado en 2009

Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells.

artículo científico publicado en 2004

Human NK Cell Subsets Redistribution in Pathological Conditions: A Role for CCR7 Receptor

artículo científico publicado en 2016

Human NK cell infusions prolong survival of metastatic human neuroblastoma-bearing NOD/scid mice

artículo científico publicado en 2007

Human NK cell response to pathogens

artículo científico

Human NK cells and NK receptors

artículo científico publicado en 2013

Human natural killer cell function and their interactions with dendritic cells

artículo científico publicado en 2003

Human natural killer cells prevent infectious mononucleosis features by targeting lytic Epstein-Barr virus infection

scientific article published on 19 December 2013

Human natural killer cells: their origin, receptors and function

artículo científico publicado en 2002

Human natural killer receptors and their ligands

artículo científico publicado en 2002

IL-12 or IL-4 prime human NK cells to mediate functionally divergent interactions with dendritic cells or tumors

artículo científico publicado en 2005

IL-21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig-like receptors

artículo científico publicado en 2003

Identification of 4Ig-B7-H3 as a neuroblastoma-associated molecule that exerts a protective role from an NK cell-mediated lysis

artículo científico publicado en 2004

Identification of HLA-E-specific alloreactive T lymphocytes: a cell subset that undergoes preferential expansion in mixed lymphocyte culture and displays a broad cytolytic activity against allogeneic cells

artículo científico publicado en 2002

Identification of NKG2A and NKp80 as specific natural killer cell markers in rhesus and pigtailed monkeys

artículo científico publicado en 2005

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule

artículo científico publicado en 2003

Identification of a subset of human natural killer cells expressing high levels of programmed death 1: A phenotypic and functional characterization

artículo científico publicado en 2016

Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46

artículo científico publicado en 2007

Imatinib and Nilotinib Off-Target Effects on Human NK Cells, Monocytes, and M2 Macrophages.

artículo científico publicado en 2017

In the thick of the fray: NK cells in inflamed tissues.

artículo científico publicado en 2007

Inhibitory 2B4 contributes to NK cell education and immunological derangements in XLP1 patients.

artículo científico publicado en 2017

Innate immunity defects in Hermansky-Pudlak type 2 syndrome

artículo científico publicado en 2006

Innate or adaptive immunity? The example of natural killer cells

artículo científico publicado en 2011

It's only innate immunity but I like it.

artículo científico publicado en 2007

Killer Ig–like receptor-mediated control of natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation ⬇️

artículo científico publicado el 20 de enero de 2011

Lysis of endogenously infected CD4+ T cell blasts by rIL-2 activated autologous natural killer cells from HIV-infected viremic individuals

artículo científico publicado en 2008

M-CSF induces the expression of a membrane-bound form of IL-18 in a subset of human monocytes differentiating in vitro toward macrophages

artículo científico publicado en 2012

Markers and function of human NK cells in normal and pathological conditions

artículo científico publicado en 2017

Melanoma cells become resistant to NK-cell-mediated killing when exposed to NK-cell numbers compatible with NK-cell infiltration in the tumor.

artículo científico publicado en 2012

Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity

artículo científico publicado en 2009

Molecular Pathogenesis of EBV Susceptibility in XLP as Revealed by Analysis of Female Carriers with Heterozygous Expression of SAP ⬇️

artículo científico publicado el 1 de noviembre de 2011

NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?

artículo científico publicado en 2016

NK cells and multiple myeloma-associated endothelial cells: molecular interactions and influence of IL-27

artículo científico publicado en 2017

NK cells and their receptors during viral infections

artículo científico publicado en 2011

NK cells recognize and kill human glioblastoma cells with stem cell-like properties

artículo científico publicado en 2009

NK-DC interaction: on the usefulness of auto-aggression

artículo científico publicado en 2005

NK-dependent DC maturation is mediated by TNFalpha and IFNgamma released upon engagement of the NKp30 triggering receptor

artículo científico publicado en 2005

NK/DC crosstalk in anti-viral response.

artículo científico

Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56bright NKG2A+++ Cells, and Yet Display Increased Degranulation and Higher Perforin Content

artículo científico publicado en 2017

Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: critical role of DNAX accessory molecule-1-poliovirus receptor interaction.

artículo científico publicado en 2004

Natural killer cell-triggering receptors in patients with acute leukaemia.

artículo científico publicado en 2003

Natural killer cells and neuroblastoma: tumor recognition, escape mechanisms, and possible novel immunotherapeutic approaches

artículo científico publicado en 2014

Natural killer cells in HIV-1 infection: dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates

artículo científico publicado en 2003

Neuroblastoma-derived TGF-β1 modulates the chemokine receptor repertoire of human resting NK cells.

artículo científico publicado en 2013

Oxysterol mixture and, in particular, 27-hydroxycholesterol drive M2 polarization of human macrophages

artículo científico publicado en 2015

PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance

artículo científico publicado en 2015

PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis

artículo científico publicado en 2005

Pathogen-induced private conversations between natural killer and dendritic cells.

artículo científico publicado en 2005

Phenotypic studies of natural killer cell subsets in human transporter associated with antigen processing deficiency

artículo científico publicado en 2007

Primitive neuroectodermal tumor in an ovarian cystic teratoma: natural killer and neuroblastoma cell analysis

artículo científico publicado en 2014

Recognition of peptide-MHC class I complexes by activating killer immunoglobulin-like receptors

artículo científico publicado en 2005

Role of alloreactive KIR2DS1(+) NK cells in haploidentical hematopoietic stem cell transplantation

artículo científico

Role of the 2B4 Receptor in CD8+ T-Cell-Dependent Immune Control of Epstein-Barr Virus Infection in Mice With Reconstituted Human Immune System Components

artículo científico publicado en 2015

Selective cross-talk among natural cytotoxicity receptors in human natural killer cells

artículo científico publicado en 2003

Shaping of adaptive immunity by innate interactions

artículo científico publicado en 2004

Structure of the human NK cell triggering receptor NKp46 ectodomain

artículo científico publicado en 2003

Structure of the saccharide-binding domain of the human natural killer cell inhibitory receptor p75/AIRM1

artículo científico publicado en 2004

Surface NK receptors and their ligands on tumor cells

artículo científico publicado en 2006

Susceptibility of human melanoma cells to autologous natural killer (NK) cell killing: HLA-related effector mechanisms and role of unlicensed NK cells

artículo científico publicado en 2009

TGF-β1 Downregulates the Expression of CX3CR1 by Inducing miR-27a-5p in Primary Human NK Cells.

artículo científico

TLR activation of tumor-associated macrophages from ovarian cancer patients triggers cytolytic activity of NK cells

artículo científico publicado en 2014

TLR-Stimulated Neutrophils Instruct NK Cells To Trigger Dendritic Cell Maturation and Promote Adaptive T Cell Responses.

artículo científico publicado en 2015

TLR/NCR/KIR: Which One to Use and When?

artículo científico

The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans

artículo científico publicado en 2009

The Innate Immune Cross Talk between NK Cells and Eosinophils Is Regulated by the Interaction of Natural Cytotoxicity Receptors with Eosinophil Surface Ligands

artículo científico publicado en 2017

The NK/DC complot

artículo científico publicado en 2009

The abundant NK cells in human secondary lymphoid tissues require activation to express killer cell Ig-like receptors and become cytolytic

artículo científico publicado en 2004

The decreased expression of Siglec-7 represents an early marker of dysfunctional natural killer-cell subsets associated with high levels of HIV-1 viremia

artículo científico publicado en 2009

The immune inhibitory receptor LAIR-1 is highly expressed by plasmacytoid dendritic cells and acts complementary with NKp44 to control IFNα production

artículo científico publicado en 2010

The inhibitory receptor IRp60 (CD300a) is expressed and functional on human mast cells

artículo científico publicado en 2005

The inhibitory receptor IRp60 (CD300a) suppresses the effects of IL-5, GM-CSF, and eotaxin on human peripheral blood eosinophils

artículo científico publicado en 2006

The interaction of human natural killer cells with either unpolarized or polarized macrophages results in different functional outcomes

artículo científico publicado en 2010

The role of chemerin in the colocalization of NK and dendritic cell subsets into inflamed tissues

scientific article published on 03 January 2007

The three-dimensional structure of the human NK cell receptor NKp44, a triggering partner in natural cytotoxicity

artículo científico publicado en 2003

Transforming growth factor beta 1 inhibits expression of NKp30 and NKG2D receptors: consequences for the NK-mediated killing of dendritic cells

artículo científico publicado en 2003

Update on natural killer cells: cross-talk with dendritic cells and role in the cure of acute myeloid leukemias

artículo científico publicado en 2003

Uptake of CCR7 and acquisition of migratory properties by human KIR+ NK cells interacting with monocyte-derived DC or EBV cell lines: regulation by KIR/HLA-class I interaction

artículo científico publicado en 2009

Uptake of CCR7 by KIR2DS4⁺ NK cells is induced upon recognition of certain HLA-C alleles

artículo científico publicado en 2015

X-linked lymphoproliferative disease: the dark side of 2b4 function

scientific article (publication date: 2001)

Lista de obras de Alessandro Moretta

Activating KIRs and NKG2C in Viral Infections: Toward NK Cell Memory?

Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors

Analysis of natural killer cells in TAP2-deficient patients: expression of functional triggering receptors and evidence for the existence of inhibitory receptor(s) that prevent lysis of normal autologous cells

Analysis of natural killer cells isolated from human decidua: Evidence that 2B4 (CD244) functions as an inhibitory receptor and blocks NK-cell function.

Analysis of the receptor-ligand interactions in the natural killer-mediated lysis of freshly isolated myeloid or lymphoblastic leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112)

Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity

B7-H6-mediated downregulation of NKp30 in NK cells contributes to ovarian carcinoma immune escape

Both CD133+ and CD133- medulloblastoma cell lines express ligands for triggering NK receptors and are susceptible to NK-mediated cytotoxicity.

Bridging innate NK cell functions with adaptive immunity.

CD59 is physically and functionally associated with natural cytotoxicity receptors and activates human NK cell-mediated cytotoxicity

Cellular ligands of activating NK receptors.

Characterization of CD56-/CD16+ natural killer (NK) cells: a highly dysfunctional NK subset expanded in HIV-infected viremic individuals

Characterization of the defective interaction between a subset of natural killer cells and dendritic cells in HIV-1 infection

Cognate HLA absence in trans diminishes human NK cell education

Comparative analysis of human NK cell activation induced by NKG2D and natural cytotoxicity receptors

Corrigendum: Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56bright NKG2A+++ Cells, and Yet Display Increased Degranulation and Higher Perforin Conten

Crystallization and preliminary crystallographic characterization of the extracellular Ig-like domain of human natural killer cell activating receptor NKp44.

DNAM-1 and PVR regulate monocyte migration through endothelial junctions

Defective expression and function of natural killer cell-triggering receptors in patients with acute myeloid leukemia

Dendritic cell editing by activated natural killer cells results in a more protective cancer-specific immune response

Early expression of triggering receptors and regulatory role of 2B4 in human natural killer cell precursors undergoing in vitro differentiation

Early liaisons between cells of the innate immune system in inflamed peripheral tissues.

Effector and regulatory events during natural killer-dendritic cell interactions

Expression and crystallographic characterization of the extracellular domain of human natural killer cell triggering receptor NKp46.

Expression and function of KIR and natural cytotoxicity receptors in NK-type lymphoproliferative diseases of granular lymphocytes.

Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction

Features of Memory-Like and PD-1(+) Human NK Cell Subsets

Functional and molecular characterization of a KIR3DL2/p140 expressing tumor-specific cytotoxic T lymphocyte clone infiltrating a human lung carcinoma

Functional characterization of natural killer cells in type I leukocyte adhesion deficiency

GPR56 as a novel marker identifying the CD56dull CD16+ NK cell subset both in blood stream and in inflamed peripheral tissues.

Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells.

Human NK Cell Subsets Redistribution in Pathological Conditions: A Role for CCR7 Receptor

Human NK cell infusions prolong survival of metastatic human neuroblastoma-bearing NOD/scid mice

Human NK cell response to pathogens

Human NK cells and NK receptors

Human natural killer cell function and their interactions with dendritic cells

Human natural killer cells prevent infectious mononucleosis features by targeting lytic Epstein-Barr virus infection

Human natural killer cells: their origin, receptors and function

Human natural killer receptors and their ligands

IL-12 or IL-4 prime human NK cells to mediate functionally divergent interactions with dendritic cells or tumors

IL-21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig-like receptors

Identification of 4Ig-B7-H3 as a neuroblastoma-associated molecule that exerts a protective role from an NK cell-mediated lysis

Identification of HLA-E-specific alloreactive T lymphocytes: a cell subset that undergoes preferential expansion in mixed lymphocyte culture and displays a broad cytolytic activity against allogeneic cells

Identification of NKG2A and NKp80 as specific natural killer cell markers in rhesus and pigtailed monkeys

Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule

Identification of a subset of human natural killer cells expressing high levels of programmed death 1: A phenotypic and functional characterization

Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46

Imatinib and Nilotinib Off-Target Effects on Human NK Cells, Monocytes, and M2 Macrophages.

In the thick of the fray: NK cells in inflamed tissues.

Inhibitory 2B4 contributes to NK cell education and immunological derangements in XLP1 patients.

Innate immunity defects in Hermansky-Pudlak type 2 syndrome

Innate or adaptive immunity? The example of natural killer cells

It's only innate immunity but I like it.

Killer Ig–like receptor-mediated control of natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation ⬇️

Lysis of endogenously infected CD4+ T cell blasts by rIL-2 activated autologous natural killer cells from HIV-infected viremic individuals

M-CSF induces the expression of a membrane-bound form of IL-18 in a subset of human monocytes differentiating in vitro toward macrophages

Markers and function of human NK cells in normal and pathological conditions

Melanoma cells become resistant to NK-cell-mediated killing when exposed to NK-cell numbers compatible with NK-cell infiltration in the tumor.

Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity

Molecular Pathogenesis of EBV Susceptibility in XLP as Revealed by Analysis of Female Carriers with Heterozygous Expression of SAP ⬇️

NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?

NK cells and multiple myeloma-associated endothelial cells: molecular interactions and influence of IL-27

NK cells and their receptors during viral infections

NK cells recognize and kill human glioblastoma cells with stem cell-like properties

NK-DC interaction: on the usefulness of auto-aggression

NK-dependent DC maturation is mediated by TNFalpha and IFNgamma released upon engagement of the NKp30 triggering receptor

NK/DC crosstalk in anti-viral response.

Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56bright NKG2A+++ Cells, and Yet Display Increased Degranulation and Higher Perforin Content

Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: critical role of DNAX accessory molecule-1-poliovirus receptor interaction.

Natural killer cell-triggering receptors in patients with acute leukaemia.

Natural killer cells and neuroblastoma: tumor recognition, escape mechanisms, and possible novel immunotherapeutic approaches

Natural killer cells in HIV-1 infection: dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates

Neuroblastoma-derived TGF-β1 modulates the chemokine receptor repertoire of human resting NK cells.

Oxysterol mixture and, in particular, 27-hydroxycholesterol drive M2 polarization of human macrophages

PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance

PVR (CD155) and Nectin-2 (CD112) as ligands of the human DNAM-1 (CD226) activating receptor: involvement in tumor cell lysis

Pathogen-induced private conversations between natural killer and dendritic cells.

Phenotypic studies of natural killer cell subsets in human transporter associated with antigen processing deficiency

Primitive neuroectodermal tumor in an ovarian cystic teratoma: natural killer and neuroblastoma cell analysis