Lista de obras - Vladimir J Kefalov - Dominio Público Uruguay

A Mixture of U.S. Food and Drug Administration-Approved Monoaminergic Drugs Protects the Retina From Light Damage in Diverse Models of Night Blindness

scientific article published on 01 April 2019

A new mouse model for stationary night blindness with mutant Slc24a1 explains the pathophysiology of the associated human disease.

artículo científico publicado en 2015

Age-related deterioration of rod vision in mice.

artículo científico publicado en 2010

An allosteric regulator of R7-RGS proteins influences light-evoked activity and glutamatergic waves in the inner retina

artículo científico publicado en 2013

An alternative pathway mediates the mouse and human cone visual cycle.

artículo científico publicado en 2009

Apo-Opsin Exists in Equilibrium Between a Predominant Inactive and a Rare Highly Active State

scientific article published on 20 November 2018

Autophagy supports color vision.

artículo científico publicado en 2015

Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization.

artículo científico publicado en 2012

Breaking the covalent bond--a pigment property that contributes to desensitization in cones.

artículo científico publicado en 2005

CRALBP supports the mammalian retinal visual cycle and cone vision

artículo científico publicado en 2015

Chromophore supply rate-limits mammalian photoreceptor dark adaptation.

artículo científico publicado en 2014

Circadian and light-driven regulation of rod dark adaptation

artículo científico publicado en 2015

Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones

scientific article published on 15 January 2019

Cone phosphodiesterase-6α' restores rod function and confers distinct physiological properties in the rod phosphodiesterase-6β-deficient rd10 mouse

artículo científico publicado en 2013

Cone-driven retinal responses are shaped by rod but not cone HCN1

Cyp27c1 Red-Shifts the Spectral Sensitivity of Photoreceptors by Converting Vitamin A1 into A2.

artículo científico publicado en 2015

DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice.

artículo científico publicado en 2014

Deletion of GRK1 causes retina degeneration through a transducin-independent mechanism.

artículo científico publicado en 2010

Dephosphorylation by protein phosphatase 2A regulates visual pigment regeneration and the dark adaptation of mammalian photoreceptors. ⬇️

artículo científico publicado en 2017

Development of an MRI biomarker sensitive to tetrameric visual arrestin 1 and its reduction via light-evoked translocation in vivo

artículo científico publicado en 2014

Differential impact of Kv8.2 loss on rod and cone signaling and degeneration

Effect of 11-cis 13-demethylretinal on phototransduction in bleach-adapted rod and cone photoreceptors.

artículo científico publicado en 2000

Effect of g protein-coupled receptor kinase 1 (Grk1) overexpression on rod photoreceptor cell viability

artículo científico publicado en 2009

Essential and synergistic roles of RP1 and RP1L1 in rod photoreceptor axoneme and retinitis pigmentosa

scientific journal article

Ex vivo ERG analysis of photoreceptors using an in vivo ERG system.

artículo científico publicado en 2014

Examining the Role of Cone-expressed RPE65 in Mouse Cone Function

artículo científico publicado en 2018

FASEB Science Research Conference on Biology and Chemistry of Vision

Function of mammalian M-cones depends on the level of CRALBP in Müller cells

artículo científico publicado en 2021

Functional interchangeability of rod and cone transducin alpha-subunits.

scholarly article

G-protein betagamma-complex is crucial for efficient signal amplification in vision

artículo científico publicado en 2011

GUCY2D Cone-Rod Dystrophy-6 is a 'Phototransduction Disease' Triggered by Abnormal Calcium Feedback on Retinal Membrane Guanylyl Cyclase 1.

artículo científico publicado en 2018

Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies

artículo científico publicado en 2015

Guanylate cyclase-activating protein 2 contributes to phototransduction and light adaptation in mouse cone photoreceptors

scientific article published on 16 March 2018

Human infrared vision is triggered by two-photon chromophore isomerization

artículo científico publicado en 2014

Interphotoreceptor retinoid-binding protein as the physiologically relevant carrier of 11-cis-retinol in the cone visual cycle

artículo científico publicado en 2011

Intra-retinal visual cycle required for rapid and complete cone dark adaptation.

artículo científico publicado en 2009

Investigating the Ca-dependent and Ca-independent mechanisms for mammalian cone light adaptation

scientific article published in Scientific Reports

LRIT1 Modulates Adaptive Changes in Synaptic Communication of Cone Photoreceptors

artículo científico publicado en 2018

Lamin B1 and lamin B2 are long-lived proteins with distinct functions in retinal development.

artículo científico publicado en 2016

Light deprivation reduces the severity of experimental diabetic retinopathy

scientific article published on 21 January 2020

Membrane anchoring subunits specify selective regulation of RGS9·Gbeta5 GAP complex in photoreceptor neurons

artículo científico publicado en 2010

Mislocalization of cone nuclei impairs cone function in mice

artículo científico publicado en 2020

Mitochondrial Calcium Uniporter (MCU) deficiency reveals an alternate path for Ca2+ uptake in photoreceptor mitochondria

artículo científico publicado en 2020

Molecular properties of rhodopsin and rod function

artículo científico publicado en 2006

Multiple Isoforms of Nesprin1 Are Integral Components of Ciliary Rootlets.

artículo científico publicado en 2017

Occupancy of the chromophore binding site of opsin activates visual transduction in rod photoreceptors

artículo científico publicado en 1999

P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis

artículo científico publicado en 2013

Phosducin-like protein 1 is essential for G-protein assembly and signaling in retinal rod photoreceptors

artículo científico publicado en 2013

Phosphorylation at Serine 21 in G protein-coupled receptor kinase 1 (GRK1) is required for normal kinetics of dark adaption in rod but not cone photoreceptors

scientific article published on 30 December 2019

Photoreceptors in a mouse model of Leigh syndrome are capable of normal light-evoked signaling

artículo científico publicado en 2019

Phototransduction in Rods and Cones

Physiological studies of the interaction between opsin and chromophore in rod and cone visual pigments.

artículo científico publicado en 2010

Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations

artículo científico publicado en 2015

Quantal noise from human red cone pigment.

artículo científico publicado en 2008

R9AP overexpression alters phototransduction kinetics in iCre75 mice.

artículo científico publicado en 2014

Redox-Responsive Hyaluronic Acid-Based Nanogels for the Topical Delivery of the Visual Chromophore to Retinal Photoreceptors

artículo científico publicado en 2021

Regulation of calcium homeostasis in the outer segments of rod and cone photoreceptors

artículo científico publicado en 2018

Regulation of mammalian cone phototransduction by recoverin and rhodopsin kinase.

artículo científico publicado en 2015

Reprogramming of adult rod photoreceptors prevents retinal degeneration

artículo científico publicado en 2013

Retinal cone photoreceptors require phosducin-like protein 1 for G protein complex assembly and signaling

artículo científico publicado en 2015

Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function.

artículo científico publicado en 2018

Retinol dehydrogenase 8 and ATP-binding cassette transporter 4 modulate dark adaptation of M-cones in mammalian retina.

artículo científico publicado en 2015

Rhodopsin kinase and arrestin binding control the decay of photoactivated rhodopsin and dark adaptation of mouse rods.

artículo científico publicado en 2016

Role of guanylyl cyclase modulation in mouse cone phototransduction.

artículo científico publicado en 2011

Role of visual pigment properties in rod and cone phototransduction

artículo científico publicado en 2003

Sensitivity and kinetics of signal transmission at the first visual synapse differentially impact visually-guided behavior

artículo científico publicado en 2015

Sensitivity of Mammalian Cone Photoreceptors to Infrared Light

artículo científico publicado en 2019

Signaling by Rod and Cone Photoreceptors: Opsin Properties, G-protein Assembly, and Mechanisms of Activation

Signaling properties of a short-wave cone visual pigment and its role in phototransduction

artículo científico publicado en 2007

Signaling states of rhodopsin in rod disk membranes lacking transducin βγ-complex

artículo científico publicado en 2012

Simultaneous ex vivo functional testing of two retinas by in vivo electroretinogram system.

artículo científico publicado en 2015

Single-cell suction recordings from mouse cone photoreceptors

artículo científico publicado en 2010

Store-operated channels regulate intracellular calcium in mammalian rods

artículo científico publicado en 2012

Systemic Retinaldehyde Treatment Corrects Retinal Oxidative Stress, Rod Dysfunction, and Impaired Visual Performance in Diabetic Mice

artículo científico publicado en 2015

The B3 Subunit of the Cone Cyclic Nucleotide-gated Channel Regulates the Light Responses of Cones and Contributes to the Channel Structural Flexibility

artículo científico publicado en 2016

The Na(+)/Ca(2+), K(+) exchanger 2 modulates mammalian cone phototransduction.

artículo científico publicado en 2016

The Na+/Ca2+, K+ exchanger NCKX4 is required for efficient cone-mediated vision

artículo científico publicado en 2017

The cone-specific visual cycle

artículo científico publicado en 2010

The mammalian cone visual cycle promotes rapid M/L-cone pigment regeneration independently of the interphotoreceptor retinoid-binding protein

artículo científico publicado en 2011

The retina visual cycle is driven by cis retinol oxidation in the outer segments of cones.

artículo científico publicado en 2017

The role of retinol dehydrogenase 10 in the cone visual cycle

artículo científico publicado en 2017

Thyroid hormone receptors mediate two distinct mechanisms of long-wavelength vision

artículo científico publicado en 2020

Transretinal ERG Recordings from Mouse Retina: Rod and Cone Photoresponses ⬇️

artículo científico publicado el 14 de marzo de 2012

Two-photon microperimetry: sensitivity of human photoreceptors to infrared light

artículo científico publicado en 2019

Use of retinal analogues for the study of visual pigment function

artículo científico publicado en 2002

Variation in Rhodopsin Kinase Expression Alters the Dim Flash Response Shut Off and the Light Adaptation in Rod Photoreceptors

artículo científico publicado en 2011

cis Retinol oxidation regulates photoreceptor access to the retina visual cycle and cone pigment regeneration.

artículo científico publicado en 2016

Lista de obras de Vladimir J Kefalov

A Mixture of U.S. Food and Drug Administration-Approved Monoaminergic Drugs Protects the Retina From Light Damage in Diverse Models of Night Blindness

A new mouse model for stationary night blindness with mutant Slc24a1 explains the pathophysiology of the associated human disease.

Age-related deterioration of rod vision in mice.

An allosteric regulator of R7-RGS proteins influences light-evoked activity and glutamatergic waves in the inner retina

An alternative pathway mediates the mouse and human cone visual cycle.

Apo-Opsin Exists in Equilibrium Between a Predominant Inactive and a Rare Highly Active State

Autophagy supports color vision.

Autosomal recessive retinitis pigmentosa E150K opsin mice exhibit photoreceptor disorganization.

Breaking the covalent bond--a pigment property that contributes to desensitization in cones.

CRALBP supports the mammalian retinal visual cycle and cone vision

Chromophore supply rate-limits mammalian photoreceptor dark adaptation.

Circadian and light-driven regulation of rod dark adaptation

Conditional deletion of Des1 in the mouse retina does not impair the visual cycle in cones

Cone phosphodiesterase-6α' restores rod function and confers distinct physiological properties in the rod phosphodiesterase-6β-deficient rd10 mouse

Cone-driven retinal responses are shaped by rod but not cone HCN1

Cyp27c1 Red-Shifts the Spectral Sensitivity of Photoreceptors by Converting Vitamin A1 into A2.

DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice.

Deletion of GRK1 causes retina degeneration through a transducin-independent mechanism.

Dephosphorylation by protein phosphatase 2A regulates visual pigment regeneration and the dark adaptation of mammalian photoreceptors. ⬇️

Development of an MRI biomarker sensitive to tetrameric visual arrestin 1 and its reduction via light-evoked translocation in vivo

Differential impact of Kv8.2 loss on rod and cone signaling and degeneration

Effect of 11-cis 13-demethylretinal on phototransduction in bleach-adapted rod and cone photoreceptors.

Effect of g protein-coupled receptor kinase 1 (Grk1) overexpression on rod photoreceptor cell viability

Essential and synergistic roles of RP1 and RP1L1 in rod photoreceptor axoneme and retinitis pigmentosa

Ex vivo ERG analysis of photoreceptors using an in vivo ERG system.

Examining the Role of Cone-expressed RPE65 in Mouse Cone Function

FASEB Science Research Conference on Biology and Chemistry of Vision

Function of mammalian M-cones depends on the level of CRALBP in Müller cells

Functional interchangeability of rod and cone transducin alpha-subunits.

G-protein betagamma-complex is crucial for efficient signal amplification in vision

GUCY2D Cone-Rod Dystrophy-6 is a 'Phototransduction Disease' Triggered by Abnormal Calcium Feedback on Retinal Membrane Guanylyl Cyclase 1.

Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies

Guanylate cyclase-activating protein 2 contributes to phototransduction and light adaptation in mouse cone photoreceptors

Human infrared vision is triggered by two-photon chromophore isomerization

Interphotoreceptor retinoid-binding protein as the physiologically relevant carrier of 11-cis-retinol in the cone visual cycle

Intra-retinal visual cycle required for rapid and complete cone dark adaptation.

Investigating the Ca-dependent and Ca-independent mechanisms for mammalian cone light adaptation

LRIT1 Modulates Adaptive Changes in Synaptic Communication of Cone Photoreceptors

Lamin B1 and lamin B2 are long-lived proteins with distinct functions in retinal development.

Light deprivation reduces the severity of experimental diabetic retinopathy

Membrane anchoring subunits specify selective regulation of RGS9·Gbeta5 GAP complex in photoreceptor neurons

Mislocalization of cone nuclei impairs cone function in mice

Mitochondrial Calcium Uniporter (MCU) deficiency reveals an alternate path for Ca2+ uptake in photoreceptor mitochondria

Molecular properties of rhodopsin and rod function

Multiple Isoforms of Nesprin1 Are Integral Components of Ciliary Rootlets.

Occupancy of the chromophore binding site of opsin activates visual transduction in rod photoreceptors

P23H opsin knock-in mice reveal a novel step in retinal rod disc morphogenesis

Phosducin-like protein 1 is essential for G-protein assembly and signaling in retinal rod photoreceptors

Phosphorylation at Serine 21 in G protein-coupled receptor kinase 1 (GRK1) is required for normal kinetics of dark adaption in rod but not cone photoreceptors

Photoreceptors in a mouse model of Leigh syndrome are capable of normal light-evoked signaling

Phototransduction in Rods and Cones

Physiological studies of the interaction between opsin and chromophore in rod and cone visual pigments.

Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations

Quantal noise from human red cone pigment.

R9AP overexpression alters phototransduction kinetics in iCre75 mice.

Redox-Responsive Hyaluronic Acid-Based Nanogels for the Topical Delivery of the Visual Chromophore to Retinal Photoreceptors

Regulation of calcium homeostasis in the outer segments of rod and cone photoreceptors

Regulation of mammalian cone phototransduction by recoverin and rhodopsin kinase.

Reprogramming of adult rod photoreceptors prevents retinal degeneration

Retinal cone photoreceptors require phosducin-like protein 1 for G protein complex assembly and signaling

Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function.

Retinol dehydrogenase 8 and ATP-binding cassette transporter 4 modulate dark adaptation of M-cones in mammalian retina.

Rhodopsin kinase and arrestin binding control the decay of photoactivated rhodopsin and dark adaptation of mouse rods.

Role of guanylyl cyclase modulation in mouse cone phototransduction.

Role of visual pigment properties in rod and cone phototransduction

Sensitivity and kinetics of signal transmission at the first visual synapse differentially impact visually-guided behavior

Sensitivity of Mammalian Cone Photoreceptors to Infrared Light

Signaling by Rod and Cone Photoreceptors: Opsin Properties, G-protein Assembly, and Mechanisms of Activation

Signaling properties of a short-wave cone visual pigment and its role in phototransduction

Signaling states of rhodopsin in rod disk membranes lacking transducin βγ-complex

Simultaneous ex vivo functional testing of two retinas by in vivo electroretinogram system.

Single-cell suction recordings from mouse cone photoreceptors

Store-operated channels regulate intracellular calcium in mammalian rods

Systemic Retinaldehyde Treatment Corrects Retinal Oxidative Stress, Rod Dysfunction, and Impaired Visual Performance in Diabetic Mice

The B3 Subunit of the Cone Cyclic Nucleotide-gated Channel Regulates the Light Responses of Cones and Contributes to the Channel Structural Flexibility

The Na(+)/Ca(2+), K(+) exchanger 2 modulates mammalian cone phototransduction.

The Na+/Ca2+, K+ exchanger NCKX4 is required for efficient cone-mediated vision

The cone-specific visual cycle

The mammalian cone visual cycle promotes rapid M/L-cone pigment regeneration independently of the interphotoreceptor retinoid-binding protein