Lista de obras - Bogdan I Florea - Dominio Público Uruguay

A Set of Activity-Based Probes to Visualize Human (Immuno)proteasome Activities

artículo científico publicado en 2015

A Specific Activity-Based Probe to Monitor Family GH59 Galactosylceramidase, the Enzyme Deficient in Krabbe Disease.

artículo científico publicado en 2016

A cleavable linker based on the levulinoyl ester for activity-based protein profiling

artículo científico publicado en 2010

A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo

artículo científico publicado en 2006

ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction

scientific article published on 01 October 2019

ADP-Ribosylation Goes Normal: Serine as the Major Site of the Modification

artículo científico publicado en 2017

Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment

artículo científico publicado en 2009

Activity-Based Profiling of 2-Oxoglutarate Oxygenases

scientific article published on 01 May 2011

Activity-Based Protein Profiling Identifies α-Ketoamides as Inhibitors for Phospholipase A2 Group XVI

artículo científico publicado en 2019

Activity-Based Protein Profiling: From Chemical Novelty to Biomedical Stalwart.

artículo científico publicado en 2017

Activity-based probes for functional interrogation of retaining β-glucuronidases

artículo científico publicado en 2017

Activity-based profiling reveals reactivity of the murine thymoproteasome-specific subunit beta5t

artículo científico publicado en 2010

Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474.

artículo científico publicado en 2017

Activity-based protein profiling: an enabling technology in chemical biology research

artículo científico

An inhibitor of proteasome β2 sites sensitizes myeloma cells to immunoproteasome inhibitors

scientific article published on 01 October 2018

Asymmetric Synthesis of Lysine Analogues with Reduced Basicity, and their Incorporation into Proteasome Inhibitors

Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division

artículo científico publicado en 2011

ChemInform Abstract: Hypersensitive Response to Over-Reactive Cysteines

Chemical Proteomic Analysis of Serine Hydrolase Activity in Niemann-Pick Type C Mouse Brain

artículo científico publicado en 2018

Chemical Proteomics Maps Brain Region Specific Activity of Endocannabinoid Hydrolases

artículo científico publicado en 2017

Coordination-Assisted Bioorthogonal Chemistry: Orthogonal Tetrazine Ligation with Vinylboronic Acid and a Strained Alkene

artículo científico publicado en 2018

Correction to "Detection of Active Mammalian GH31 α-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes"

artículo científico publicado en 2017

Detection of Active Mammalian GH31 α-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes

artículo científico publicado en 2016

Development and application of an in vitro apoptin kinase assay

artículo científico publicado en 2011

Development of a Retinal-Based Probe for the Profiling of Retinaldehyde Dehydrogenases in Cancer Cells

scientific article published on 12 December 2019

Development of an activity-based probe and in silico design reveal highly selective inhibitors for diacylglycerol lipase-α in brain

artículo científico publicado en 2013

Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition

artículo científico publicado en 2016

Dynamic and Functional Profiling of Xylan-Degrading Enzymes in Aspergillus Secretomes Using Activity-Based Probes

scientific article published on 24 May 2019

Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4

artículo científico publicado en 2006

Enantioselective synthesis of adamantylalanine and carboranylalanine and their incorporation into the proteasome inhibitor bortezomib

artículo científico publicado en 2016

Enhancement of bronchial octreotide absorption by chitosan and N-trimethyl chitosan shows linear in vitro/in vivo correlation

artículo científico publicado en 2005

Evidence of P-glycoprotein mediated apical to basolateral transport of flunisolide in human broncho-tracheal epithelial cells (Calu-3)

artículo científico publicado en 2001

Fluorescent Probes from Aromatic Polycyclic Nitrile Oxides: Isoxazoles versus Dihydro-1λ3,3,2λ4-Oxazaborinines

artículo científico publicado en 2019

Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons

artículo científico publicado en 2015

Hydrophobic Interactions Contribute to Conformational Stabilization of Endoglycoceramidase II by Mechanism-Based Probes.

artículo científico publicado en 2016

Identification and isolation of lantibiotics from culture: a bioorthogonal chemistry approach

article

Identification of an internalising peptide in differentiated Calu-3 cells by phage display technology; application to gene delivery to the airways.

artículo científico publicado en 2003

Identification of glucose kinase-dependent and -independent pathways for carbon control of primary metabolism, development and antibiotic production in Streptomyces coelicolor by quantitative proteomics

artículo científico publicado en 2012

Identification of glucose kinase-dependent and -independent pathways for carbon control of primary metabolism, development and antibiotic production in Streptomyces coelicolor by quantitative proteomics

artículo científico publicado en 2017

Identification of new quorum sensing autoinducer binding partners in Pseudomonas aeruginosa using photoaffinity probes

artículo científico publicado en 2017

Identification of α,β-Hydrolase Domain Containing Protein 6 as a Diacylglycerol Lipase in Neuro-2a Cells

scientific article published on 26 November 2019

In vitro and in vivo comparative and competitive activity-based protein profiling of GH29 α-l-fucosidases.

artículo científico publicado en 2015

Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites

artículo científico publicado en 2013

Incorporation of fluorinated phenylalanine generates highly specific inhibitor of proteasome's chymotrypsin-like sites

artículo científico publicado en 2010

Intertwined Precursor Supply during Biosynthesis of the Catecholate-Hydroxamate Siderophores Qinichelins in Streptomyces sp. MBT76.

artículo científico publicado en 2017

Mapping in vivo target interaction profiles of covalent inhibitors using chemical proteomics with label-free quantification

artículo científico publicado en 2018

Milder degenerative effects of Carfilzomib vs. Bortezomib in the Drosophila model: a link to clinical adverse events

artículo científico publicado en 2017

Mixing of peptides and electrophilic traps gives rise to potent, broad-spectrum proteasome inhibitors

artículo científico publicado en 2007

Natural product proteomining, a quantitative proteomics platform, allows rapid discovery of biosynthetic gene clusters for different classes of natural products

artículo científico publicado en 2014

Nature of pharmacophore influences active site specificity of proteasome inhibitors

artículo científico publicado en 2010

New irreversible α-L-iduronidase inhibitors and activity-based probes

artículo científico publicado en 2018

Non-lethal proteasome inhibition activates pro-tumorigenic pathways in multiple myeloma cells

artículo científico publicado en 2019

Novel activity-based probes for broad-spectrum profiling of retaining β-exoglucosidases in situ and in vivo.

artículo científico publicado en 2012

PABPN1-Dependent mRNA Processing Induces Muscle Wasting.

artículo científico publicado en 2016

Peptido Sulfonyl Fluorides as New Powerful Proteasome Inhibitors

artículo científico publicado en 2012

Phosphate Promotes the Recovery of Mycobacterium tuberculosis β-Lactamase from Clavulanic Acid Inhibition

artículo científico publicado en 2017

Photo-crosslinking of clinically relevant kinases using H89-derived photo-affinity probes

artículo científico publicado en 2016

Probing the proteasome cavity in three steps: bio-orthogonal photo-reactive suicide substrates

artículo científico publicado en 2010

Proteasomal activity-based probes mark protein homeostasis in muscles

artículo científico publicado en 2017

Proteasome Subunit Selective Activity-Based Probes Report on Proteasome Core Particle Composition in a Native Polyacrylamide Gel Electrophoresis Fluorescence-Resonance Energy Transfer Assay

artículo científico publicado en 2016

Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification.

artículo científico publicado en 2017

Proteasome inhibitor-adapted myeloma cells are largely independent from proteasome activity and show complex proteomic changes, in particular in redox and energy metabolism

artículo científico publicado en 2016

Receptor-mediated targeting of cathepsins in professional antigen presenting cells

artículo científico publicado en 2009

Relative quantification of proteasome activity by activity-based protein profiling and LC-MS/MS.

artículo científico publicado en 2013

STA-55, an Easily Accessible, Broad-Spectrum, Activity-Based Aldehyde Dehydrogenase Probe

scientific article published on 27 January 2020

Scope and Limitations of Boron Fluorescent Complexes from Stable Nitrile Oxides in ABPP Assays

scientific article published on 29 April 2019

Specific cell-permeable inhibitor of proteasome trypsin-like sites selectively sensitizes myeloma cells to bortezomib and carfilzomib

artículo científico publicado en 2011

Stabilization of Glucocerebrosidase by Active Site Occupancy.

artículo científico publicado en 2017

Stage-Dependent Axon Transport of Proteasomes Contributes to Axon Development

artículo científico publicado en 2015

Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits

scientific article published on 05 February 2019

Structure-Based Design of β5c Selective Inhibitors of Human Constitutive Proteasomes

artículo científico publicado en 2016

Sugar amino acid based peptide epoxyketones as potential proteasome inhibitors

artículo científico publicado en 2010

Synthetic Studies on the Preparation of Alanyl Epoxysulfones as Cathepsin Cysteine Protease Electrophilic Traps

artículo científico publicado en 2015

Syringolin A selectively labels the 20 S proteasome in murine EL4 and wild-type and bortezomib-adapted leukaemic cell lines

artículo científico publicado en 2009

Targeted pH-dependent fluorescent activity-based cathepsin probes

artículo científico publicado en 2011

The natural product hybrid of Syringolin A and Glidobactin A synergizes proteasome inhibition potency with subsite selectivity

artículo científico publicado en 2010

The proteasome modulates endocytosis specifically in glomerular cells to promote kidney filtration

artículo científico publicado en 2024

Toward understanding induction of oxidative stress and apoptosis by proteasome inhibitors

artículo científico

Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines.

artículo científico publicado en 2017

Transfection efficiency and toxicity of polyethylenimine in differentiated Calu-3 and nondifferentiated COS-1 cell cultures ⬇️

artículo científico publicado en 2002

Transport and local metabolism of budesonide and fluticasone propionate in a human bronchial epithelial cell line (Calu-3).

artículo científico publicado en 2002

Tripeptidyl Peptidase II Mediates Levels of Nuclear Phosphorylated ERK1 and ERK2.

artículo científico

Trypanosoma brucei: Inhibition of cathepsin L is sufficient to kill bloodstream forms

artículo científico publicado en 2019

Trypanosoma brucei: β2-selective proteasome inhibitors do not block the proteasomal trypsin-like activity but are trypanocidal

artículo científico publicado en 2019

Two-Step Bioorthogonal Activity-Based Protein Profiling of Individual Human Proteasome Catalytic Sites

scientific article published on 08 November 2019

Two-step bioorthogonal activity-based proteasome profiling using copper-free click reagents: a comparative study

artículo científico publicado en 2011

Use of Proteasome Inhibitors

scientific article published on 01 April 2015

Visualizing Proteasome Activity and Intracellular Localization Using Fluorescent Proteins and Activity-Based Probes

scientific article published on 20 August 2019

α-galactosidase A1.1 can functionally complement human α-galactosidase A deficiency associated with Fabry disease

artículo científico publicado en 2018

Lista de obras de Bogdan I Florea

A Set of Activity-Based Probes to Visualize Human (Immuno)proteasome Activities

A Specific Activity-Based Probe to Monitor Family GH59 Galactosylceramidase, the Enzyme Deficient in Krabbe Disease.

A cleavable linker based on the levulinoyl ester for activity-based protein profiling

A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo

ABHD2 Inhibitor Identified by Activity-Based Protein Profiling Reduces Acrosome Reaction

ADP-Ribosylation Goes Normal: Serine as the Major Site of the Modification

Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment

Activity-Based Profiling of 2-Oxoglutarate Oxygenases

Activity-Based Protein Profiling Identifies α-Ketoamides as Inhibitors for Phospholipase A2 Group XVI

Activity-Based Protein Profiling: From Chemical Novelty to Biomedical Stalwart.

Activity-based probes for functional interrogation of retaining β-glucuronidases

Activity-based profiling reveals reactivity of the murine thymoproteasome-specific subunit beta5t

Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474.

Activity-based protein profiling: an enabling technology in chemical biology research

An inhibitor of proteasome β2 sites sensitizes myeloma cells to immunoproteasome inhibitors

Asymmetric Synthesis of Lysine Analogues with Reduced Basicity, and their Incorporation into Proteasome Inhibitors

Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division

ChemInform Abstract: Hypersensitive Response to Over-Reactive Cysteines

Chemical Proteomic Analysis of Serine Hydrolase Activity in Niemann-Pick Type C Mouse Brain

Chemical Proteomics Maps Brain Region Specific Activity of Endocannabinoid Hydrolases

Coordination-Assisted Bioorthogonal Chemistry: Orthogonal Tetrazine Ligation with Vinylboronic Acid and a Strained Alkene

Correction to "Detection of Active Mammalian GH31 α-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes"

Detection of Active Mammalian GH31 α-Glucosidases in Health and Disease Using In-Class, Broad-Spectrum Activity-Based Probes

Development and application of an in vitro apoptin kinase assay

Development of a Retinal-Based Probe for the Profiling of Retinaldehyde Dehydrogenases in Cancer Cells

Development of an activity-based probe and in silico design reveal highly selective inhibitors for diacylglycerol lipase-α in brain

Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition

Dynamic and Functional Profiling of Xylan-Degrading Enzymes in Aspergillus Secretomes Using Activity-Based Probes

Dynamic assembly of end-joining complexes requires interaction between Ku70/80 and XRCC4

Enantioselective synthesis of adamantylalanine and carboranylalanine and their incorporation into the proteasome inhibitor bortezomib

Enhancement of bronchial octreotide absorption by chitosan and N-trimethyl chitosan shows linear in vitro/in vivo correlation

Evidence of P-glycoprotein mediated apical to basolateral transport of flunisolide in human broncho-tracheal epithelial cells (Calu-3)

Fluorescent Probes from Aromatic Polycyclic Nitrile Oxides: Isoxazoles versus Dihydro-1λ3,3,2λ4-Oxazaborinines

Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons

Hydrophobic Interactions Contribute to Conformational Stabilization of Endoglycoceramidase II by Mechanism-Based Probes.

Identification and isolation of lantibiotics from culture: a bioorthogonal chemistry approach

Identification of an internalising peptide in differentiated Calu-3 cells by phage display technology; application to gene delivery to the airways.

Identification of glucose kinase-dependent and -independent pathways for carbon control of primary metabolism, development and antibiotic production in Streptomyces coelicolor by quantitative proteomics

Identification of glucose kinase-dependent and -independent pathways for carbon control of primary metabolism, development and antibiotic production in Streptomyces coelicolor by quantitative proteomics

Identification of new quorum sensing autoinducer binding partners in Pseudomonas aeruginosa using photoaffinity probes

Identification of α,β-Hydrolase Domain Containing Protein 6 as a Diacylglycerol Lipase in Neuro-2a Cells

In vitro and in vivo comparative and competitive activity-based protein profiling of GH29 α-l-fucosidases.

Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites

Incorporation of fluorinated phenylalanine generates highly specific inhibitor of proteasome's chymotrypsin-like sites

Intertwined Precursor Supply during Biosynthesis of the Catecholate-Hydroxamate Siderophores Qinichelins in Streptomyces sp. MBT76.

Mapping in vivo target interaction profiles of covalent inhibitors using chemical proteomics with label-free quantification

Milder degenerative effects of Carfilzomib vs. Bortezomib in the Drosophila model: a link to clinical adverse events

Mixing of peptides and electrophilic traps gives rise to potent, broad-spectrum proteasome inhibitors

Natural product proteomining, a quantitative proteomics platform, allows rapid discovery of biosynthetic gene clusters for different classes of natural products

Nature of pharmacophore influences active site specificity of proteasome inhibitors

New irreversible α-L-iduronidase inhibitors and activity-based probes

Non-lethal proteasome inhibition activates pro-tumorigenic pathways in multiple myeloma cells

Novel activity-based probes for broad-spectrum profiling of retaining β-exoglucosidases in situ and in vivo.

PABPN1-Dependent mRNA Processing Induces Muscle Wasting.

Peptido Sulfonyl Fluorides as New Powerful Proteasome Inhibitors

Phosphate Promotes the Recovery of Mycobacterium tuberculosis β-Lactamase from Clavulanic Acid Inhibition

Photo-crosslinking of clinically relevant kinases using H89-derived photo-affinity probes

Probing the proteasome cavity in three steps: bio-orthogonal photo-reactive suicide substrates

Proteasomal activity-based probes mark protein homeostasis in muscles

Proteasome Subunit Selective Activity-Based Probes Report on Proteasome Core Particle Composition in a Native Polyacrylamide Gel Electrophoresis Fluorescence-Resonance Energy Transfer Assay

Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification.

Proteasome inhibitor-adapted myeloma cells are largely independent from proteasome activity and show complex proteomic changes, in particular in redox and energy metabolism

Receptor-mediated targeting of cathepsins in professional antigen presenting cells

Relative quantification of proteasome activity by activity-based protein profiling and LC-MS/MS.

STA-55, an Easily Accessible, Broad-Spectrum, Activity-Based Aldehyde Dehydrogenase Probe

Scope and Limitations of Boron Fluorescent Complexes from Stable Nitrile Oxides in ABPP Assays

Specific cell-permeable inhibitor of proteasome trypsin-like sites selectively sensitizes myeloma cells to bortezomib and carfilzomib

Stabilization of Glucocerebrosidase by Active Site Occupancy.

Stage-Dependent Axon Transport of Proteasomes Contributes to Axon Development

Structure-Based Design of Inhibitors Selective for Human Proteasome β2c or β2i Subunits

Structure-Based Design of β5c Selective Inhibitors of Human Constitutive Proteasomes

Sugar amino acid based peptide epoxyketones as potential proteasome inhibitors

Synthetic Studies on the Preparation of Alanyl Epoxysulfones as Cathepsin Cysteine Protease Electrophilic Traps

Syringolin A selectively labels the 20 S proteasome in murine EL4 and wild-type and bortezomib-adapted leukaemic cell lines

Targeted pH-dependent fluorescent activity-based cathepsin probes

The natural product hybrid of Syringolin A and Glidobactin A synergizes proteasome inhibition potency with subsite selectivity

The proteasome modulates endocytosis specifically in glomerular cells to promote kidney filtration

Toward understanding induction of oxidative stress and apoptosis by proteasome inhibitors

Towards broad spectrum activity-based glycosidase probes: synthesis and evaluation of deoxygenated cyclophellitol aziridines.