Lista de obras - Tony Bruns - Dominio Público Uruguay

A Multi-Omics Analysis of Mucosal-Associated-Invariant T Cells Reveals Key Drivers of Distinct Modes of Activation

artículo científico publicado en 2021

A Prospective Multicentre Study of the Epidemiology and Outcomes of Bloodstream Infection in Cirrhotic Patients

artículo científico publicado en 2017

A confocal view of the intestinal microcirculation in a patient with Crohn disease and portal vein thrombosis

artículo científico publicado en 2011

Abnormal glucose tolerance: a predictor of 30-day mortality in patients with decompensated liver cirrhosis ⬇️

artículo científico publicado el 9 de marzo de 2011

Acid Sphingomyelinase Inhibition Prevents Development of Sepsis Sequelae in the Murine Liver

artículo científico publicado en 2017

Acute Hepatitis E is an Underreported Cause of Severe Acute Liver Injury

artículo científico publicado en 2019

Acute-on-Chronic Liver Failure

artículo científico publicado en 2018

Acute-on-chronic liver failure - new Definition of a complex clinical picture

artículo científico publicado en 2016

Aspects of pulmonary drug delivery strategies for infections in cystic fibrosis--where do we stand?

artículo científico publicado en 2015

Attenuated antigen-specific T cell responses in cirrhosis are accompanied by elevated serum interleukin-10 levels and down-regulation of HLA-DR on monocytes

artículo científico publicado en 2013

Autoimmune hepatitis in an HIV-infected patient: an intriguing association

artículo científico publicado en 2012

Bidirectional transendothelial migration of monocytes across hepatic sinusoidal endothelium shapes monocyte differentiation and regulates the balance between immunity and tolerance in liver.

artículo científico publicado en 2015

Blood group B is associated with azathioprine-induced acute pancreatitis in patients with IBD

artículo científico publicado en 2016

CMV infection of human sinusoidal endothelium regulates hepatic T cell recruitment and activation.

artículo científico publicado en 2015

Calcineurin inhibitors or anti-TNF-α agents in severe ulcerative colitis: available options and limitations

artículo científico publicado en 2012

Candida albicans β-Glucan Differentiates Human Monocytes Into a Specific Subset of Macrophages

artículo científico publicado en 2018

Cholestatic hepatitis, acute acalculous cholecystitis, and hemolytic anemia: primary Epstein-Barr virus infection under azathioprine.

artículo científico publicado en 2009

Circulating Bile Acids in Liver Failure Activate TGR5 and Induce Monocyte Dysfunction

article published in 2021

Clinical relevance and cellular source of elevated soluble urokinase plasminogen activator receptor (suPAR) in acute liver failure.

artículo científico publicado en 2014

Drug monitoring in inflammatory bowel disease: helpful or dispensable?

artículo científico publicado en 2009

Dual-sugar tests of small intestinal permeability are poor predictors of bacterial infections and mortality in cirrhosis: A prospective study

artículo científico publicado en 2016

Effects of Age and Sex of Response to Ursodeoxycholic Acid and Transplant-free Survival in Patients With Primary Biliary Cholangitis

scientific article published on 04 January 2019

Effects of Antibiotics on Gut Microbiota.

artículo científico publicado en 2016

Emergence of spontaneous bacterial peritonitis due to enterococci - risk factors and outcome in a 12-year retrospective study.

artículo científico publicado en 2012

Empirical antibiotic therapy in intra-abdomial infections: cases and evidence-based therapeutic recommendations

artículo científico publicado en 2013

Etiologies and outcomes of acute liver failure in Germany.

artículo científico publicado en 2012

Extended Infusion of β-Lactams for Bloodstream Infection in Patients With Liver Cirrhosis: An Observational Multicenter Study

scientific article published in 2019

External ventricular drain infections: risk factors and outcome.

artículo científico publicado en 2014

Factors Associated With Progression and Outcomes of Early Stage Primary Biliary Cholangitis

scientific article published on 13 August 2019

Fungal Infections in Patients With Infected Pancreatic Necrosis and Pseudocysts: Risk Factors and Outcome.

artículo científico publicado en 2017

Further evidence for the relevance of TLR2 gene variants in spontaneous bacterial peritonitis

article

Genetic Variants in the Promoter Region of the Macrophage Migration Inhibitory Factor are Associated with the Severity of Hepatitis C Virus-Induced Liver Fibrosis

artículo científico publicado en 2019

Guidelines for the Quantification of HIV and HCV in Small Volume Whole Blood Samples ⬇️

artículo científico publicado el 1 de enero de 2012

Hepatocellular carcinoma surveillance in hepatitis B virus-infected individuals: Who and how?

artículo científico publicado en 2015

Homozygous carrier of the NOD2 1007fs frame-shift mutation presenting with refractory community-acquired spontaneous bacterial peritonitis and developing fatal pulmonary mucormycosis: A case report.

artículo científico publicado en 2011

Identification of bacterial DNA in neutrocytic and non-neutrocytic cirrhotic ascites by means of a multiplex polymerase chain reaction.

artículo científico publicado en 2009

Impaired Transmigration of Myeloid-Derived Suppressor Cells across Human Sinusoidal Endothelium Is Associated with Decreased Expression of CD13.

artículo científico publicado en 2017

Induction of innate immune memory via microRNA targeting of chromatin remodelling factors

artículo científico publicado en 2018

Intestinal CCL25 expression is increased in colitis and correlates with inflammatory activity

artículo científico publicado en 2016

Letter: predicting azathioprine-associated pancreatitis in IBD-phenotype or genotype?

artículo científico publicado en 2018

Letter: serum vitamin D levels in primary biliary cirrhosis.

artículo científico publicado en 2015

Letter: the therapeutic potential of targeting CCL25/CCR9 in colonic inflammatory bowel disease - reading between the lines

artículo científico publicado en 2016

Loss of CD28 expression by liver-infiltrating T cells contributes to pathogenesis of primary sclerosing cholangitis

artículo científico publicado en 2014

Low ascitic fluid protein does not indicate an increased risk for spontaneous bacterial peritonitis in current cohorts

scientific article published on 24 May 2015

Low circulating chemerin levels correlate with hepatic dysfunction and increased mortality in decompensated liver cirrhosis.

artículo científico publicado en 2018

Low serum transferrin correlates with acute-on-chronic organ failure and indicates short-term mortality in decompensated cirrhosis

artículo científico publicado en 2016

Major Hepatic Complications in Ursodeoxycholic Acid-Treated Patients With Primary Biliary Cholangitis: Risk Factors and Time Trends in Incidence and Outcome

artículo científico publicado en 2017

Medical and surgical therapy of inflammatory bowel disease in the elderly - prospects and complications.

artículo científico publicado en 2011

Microbial spectrum of intra-abdominal abscesses in perforating Crohn's disease: Results from a prospective German Registry.

artículo científico publicado en 2018

Mid-regional pro-adrenomedullin (MR-proADM): An even better prognostic biomarker than C-reactive protein to predict short-term survival in patients with decompensated cirrhosis at risk of infection? ⬇️

artículo científico publicado el 11 de agosto de 2012

Milder disease stage in patients with primary biliary cholangitis over a 44-year period: A changing natural history.

artículo científico publicado en 2017

Mortality after urinary tract infections in patients with advanced cirrhosis – Relevance of acute kidney injury and comorbidities ⬇️

artículo científico publicado el 1 de febrero de 2013

Motivation of patients with inflammatory bowel disease to participate in a clinical trial

artículo científico publicado en 2016

NOD2 Risk Variants and Pathological Bacterial Translocation in Decompensated Cirrhosis.

artículo científico publicado en 2016

NOD2 gene variants are a risk factor for culture‐positive spontaneous bacterial peritonitis and monomicrobial bacterascites in cirrhosis ⬇️

artículo científico publicado el 13 de junio de 2011

Nonlinear Multimodal Imaging Characteristics of Early Septic Liver Injury in a Mouse Model of Peritonitis

artículo científico publicado en 2019

Optimising risk stratification in primary biliary cirrhosis: AST/platelet ratio index predicts outcome independent of ursodeoxycholic acid response.

artículo científico publicado en 2014

Primed circulating monocytes are a source of IL-1β in patients with cirrhosis and ascites

artículo científico publicado en 2020

Pulmonary co-infection with nocardia species and nontuberculous mycobacteria mimicking miliary tuberculosis in a patient with Crohn's disease under combined immunosuppressive therapy

artículo científico publicado en 2018

Recruitment mechanisms of primary and malignant B cells to the human liver

artículo científico publicado en 2012

Recurrent fever and bacteraemia after endoscopic variceal haemostasis with cyanoacrylate: a case report.

artículo científico publicado en 2011

Reply to: “AST/platelet ratio index associates with progression to hepatic failure and correlates with histological fibrosis stage in Japanese patients with primary biliary cirrhosis”

scientific article published on 23 August 2014

Reticulocyte count and hemoglobin concentration predict survival in candidates for liver transplantation.

artículo científico publicado en 2014

Risk Factors for Multi-Drug Resistant Pathogens and Failure of Empiric First-Line Therapy in Acute Cholangitis

artículo científico publicado en 2017

Risk factors and outcome of bacterial infections in cirrhosis

artículo científico publicado en 2014

Risk factors for QT interval prolongation owing to acute gastrointestinal haemorrhage in patients with cirrhosis.

artículo científico publicado en 2012

SARS-CoV-2 as an extrahepatic precipitator of acute-on-chronic liver failure

artículo científico publicado en 2020

Serum metabolic signatures in patients with overt hepatic encephalopathy.

artículo científico publicado en 2017

Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases

artículo científico publicado en 2021

Short-Term Isocaloric Intake of a Fructose- but not Glucose-Rich Diet Affects Bacterial Endotoxin Concentrations and Markers of Metabolic Health in Normal Weight Healthy Subjects

artículo científico publicado en 2019

Spontaneous and secondary bacterial peritonitis in cirrhotic patients with ascites

artículo científico publicado en 2011

Subacute liver failure induced by adalimumab

artículo científico publicado en 2011

The ATG16L1 gene variant rs2241880 (p.T300A) is associated with susceptibility to HCC in patients with cirrhosis

scientific article published on 11 September 2019

The INCA trial (Impact of NOD2 genotype-guided antibiotic prevention on survival in patients with liver Cirrhosis and Ascites): study protocol for a randomized controlled trial.

artículo científico publicado en 2015

The augmented neutrophil respiratory burst in response to Escherichia coli is reduced in liver cirrhosis during infection

artículo científico publicado en 2011

The detection of the cytomegalovirus DNA in the colonic mucosa of patients with ulcerative colitis is associated with increased long-term risk of proctocolectomy: results from an outpatient IBD clinic

artículo científico publicado en 2018

Thumb sucking or nail biting in childhood and adolescence is associated with an increased risk of Crohn's disease: results from a large case-control study

artículo científico publicado en 2020

Transcriptional Suppression of the NLRP3 Inflammasome and Cytokine Release in Primary Macrophages by Low-Dose Anthracyclines

scientific article published on 28 December 2019

Vascular adhesion protein-1 is elevated in primary sclerosing cholangitis, is predictive of clinical outcome and facilitates recruitment of gut-tropic lymphocytes to liver in a substrate-dependent manner.

artículo científico publicado en 2017

Vedolizumab provides clinical benefit over 1 year in patients with active inflammatory bowel disease - a prospective multicenter observational study.

artículo científico publicado en 2016

[54-year-old male with hepatic cirrhosis and therapy-associated torsade de pointes tachycardia]

artículo científico publicado en 2011

[Cut a long story too short: Challenges in clinical research]

scientific article published on 28 February 2012

Lista de obras de Tony Bruns

A Multi-Omics Analysis of Mucosal-Associated-Invariant T Cells Reveals Key Drivers of Distinct Modes of Activation

A Prospective Multicentre Study of the Epidemiology and Outcomes of Bloodstream Infection in Cirrhotic Patients

A confocal view of the intestinal microcirculation in a patient with Crohn disease and portal vein thrombosis

Abnormal glucose tolerance: a predictor of 30-day mortality in patients with decompensated liver cirrhosis ⬇️

Acid Sphingomyelinase Inhibition Prevents Development of Sepsis Sequelae in the Murine Liver

Acute Hepatitis E is an Underreported Cause of Severe Acute Liver Injury

Acute-on-Chronic Liver Failure

Acute-on-chronic liver failure - new Definition of a complex clinical picture

Aspects of pulmonary drug delivery strategies for infections in cystic fibrosis--where do we stand?

Attenuated antigen-specific T cell responses in cirrhosis are accompanied by elevated serum interleukin-10 levels and down-regulation of HLA-DR on monocytes

Autoimmune hepatitis in an HIV-infected patient: an intriguing association

Bidirectional transendothelial migration of monocytes across hepatic sinusoidal endothelium shapes monocyte differentiation and regulates the balance between immunity and tolerance in liver.

Blood group B is associated with azathioprine-induced acute pancreatitis in patients with IBD

CMV infection of human sinusoidal endothelium regulates hepatic T cell recruitment and activation.

Calcineurin inhibitors or anti-TNF-α agents in severe ulcerative colitis: available options and limitations

Candida albicans β-Glucan Differentiates Human Monocytes Into a Specific Subset of Macrophages

Cholestatic hepatitis, acute acalculous cholecystitis, and hemolytic anemia: primary Epstein-Barr virus infection under azathioprine.

Circulating Bile Acids in Liver Failure Activate TGR5 and Induce Monocyte Dysfunction

Clinical relevance and cellular source of elevated soluble urokinase plasminogen activator receptor (suPAR) in acute liver failure.

Drug monitoring in inflammatory bowel disease: helpful or dispensable?

Dual-sugar tests of small intestinal permeability are poor predictors of bacterial infections and mortality in cirrhosis: A prospective study

Effects of Age and Sex of Response to Ursodeoxycholic Acid and Transplant-free Survival in Patients With Primary Biliary Cholangitis

Effects of Antibiotics on Gut Microbiota.

Emergence of spontaneous bacterial peritonitis due to enterococci - risk factors and outcome in a 12-year retrospective study.

Empirical antibiotic therapy in intra-abdomial infections: cases and evidence-based therapeutic recommendations

Etiologies and outcomes of acute liver failure in Germany.

Extended Infusion of β-Lactams for Bloodstream Infection in Patients With Liver Cirrhosis: An Observational Multicenter Study

External ventricular drain infections: risk factors and outcome.

Factors Associated With Progression and Outcomes of Early Stage Primary Biliary Cholangitis

Fungal Infections in Patients With Infected Pancreatic Necrosis and Pseudocysts: Risk Factors and Outcome.

Further evidence for the relevance of TLR2 gene variants in spontaneous bacterial peritonitis

Genetic Variants in the Promoter Region of the Macrophage Migration Inhibitory Factor are Associated with the Severity of Hepatitis C Virus-Induced Liver Fibrosis

Guidelines for the Quantification of HIV and HCV in Small Volume Whole Blood Samples ⬇️

Hepatocellular carcinoma surveillance in hepatitis B virus-infected individuals: Who and how?

Homozygous carrier of the NOD2 1007fs frame-shift mutation presenting with refractory community-acquired spontaneous bacterial peritonitis and developing fatal pulmonary mucormycosis: A case report.

Identification of bacterial DNA in neutrocytic and non-neutrocytic cirrhotic ascites by means of a multiplex polymerase chain reaction.

Impaired Transmigration of Myeloid-Derived Suppressor Cells across Human Sinusoidal Endothelium Is Associated with Decreased Expression of CD13.

Induction of innate immune memory via microRNA targeting of chromatin remodelling factors

Intestinal CCL25 expression is increased in colitis and correlates with inflammatory activity

Letter: predicting azathioprine-associated pancreatitis in IBD-phenotype or genotype?

Letter: serum vitamin D levels in primary biliary cirrhosis.

Letter: the therapeutic potential of targeting CCL25/CCR9 in colonic inflammatory bowel disease - reading between the lines

Loss of CD28 expression by liver-infiltrating T cells contributes to pathogenesis of primary sclerosing cholangitis

Low ascitic fluid protein does not indicate an increased risk for spontaneous bacterial peritonitis in current cohorts

Low circulating chemerin levels correlate with hepatic dysfunction and increased mortality in decompensated liver cirrhosis.

Low serum transferrin correlates with acute-on-chronic organ failure and indicates short-term mortality in decompensated cirrhosis

Major Hepatic Complications in Ursodeoxycholic Acid-Treated Patients With Primary Biliary Cholangitis: Risk Factors and Time Trends in Incidence and Outcome

Medical and surgical therapy of inflammatory bowel disease in the elderly - prospects and complications.

Microbial spectrum of intra-abdominal abscesses in perforating Crohn's disease: Results from a prospective German Registry.

Mid-regional pro-adrenomedullin (MR-proADM): An even better prognostic biomarker than C-reactive protein to predict short-term survival in patients with decompensated cirrhosis at risk of infection? ⬇️

Milder disease stage in patients with primary biliary cholangitis over a 44-year period: A changing natural history.

Mortality after urinary tract infections in patients with advanced cirrhosis – Relevance of acute kidney injury and comorbidities ⬇️

Motivation of patients with inflammatory bowel disease to participate in a clinical trial

NOD2 Risk Variants and Pathological Bacterial Translocation in Decompensated Cirrhosis.

NOD2 gene variants are a risk factor for culture‐positive spontaneous bacterial peritonitis and monomicrobial bacterascites in cirrhosis ⬇️

Nonlinear Multimodal Imaging Characteristics of Early Septic Liver Injury in a Mouse Model of Peritonitis

Optimising risk stratification in primary biliary cirrhosis: AST/platelet ratio index predicts outcome independent of ursodeoxycholic acid response.

Primed circulating monocytes are a source of IL-1β in patients with cirrhosis and ascites

Pulmonary co-infection with nocardia species and nontuberculous mycobacteria mimicking miliary tuberculosis in a patient with Crohn's disease under combined immunosuppressive therapy

Recruitment mechanisms of primary and malignant B cells to the human liver

Recurrent fever and bacteraemia after endoscopic variceal haemostasis with cyanoacrylate: a case report.

Reply to: “AST/platelet ratio index associates with progression to hepatic failure and correlates with histological fibrosis stage in Japanese patients with primary biliary cirrhosis”

Reticulocyte count and hemoglobin concentration predict survival in candidates for liver transplantation.

Risk Factors for Multi-Drug Resistant Pathogens and Failure of Empiric First-Line Therapy in Acute Cholangitis

Risk factors and outcome of bacterial infections in cirrhosis

Risk factors for QT interval prolongation owing to acute gastrointestinal haemorrhage in patients with cirrhosis.

SARS-CoV-2 as an extrahepatic precipitator of acute-on-chronic liver failure

Serum metabolic signatures in patients with overt hepatic encephalopathy.

Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases

Short-Term Isocaloric Intake of a Fructose- but not Glucose-Rich Diet Affects Bacterial Endotoxin Concentrations and Markers of Metabolic Health in Normal Weight Healthy Subjects

Spontaneous and secondary bacterial peritonitis in cirrhotic patients with ascites

Subacute liver failure induced by adalimumab

The ATG16L1 gene variant rs2241880 (p.T300A) is associated with susceptibility to HCC in patients with cirrhosis

The INCA trial (Impact of NOD2 genotype-guided antibiotic prevention on survival in patients with liver Cirrhosis and Ascites): study protocol for a randomized controlled trial.

The augmented neutrophil respiratory burst in response to Escherichia coli is reduced in liver cirrhosis during infection

The detection of the cytomegalovirus DNA in the colonic mucosa of patients with ulcerative colitis is associated with increased long-term risk of proctocolectomy: results from an outpatient IBD clinic

Thumb sucking or nail biting in childhood and adolescence is associated with an increased risk of Crohn's disease: results from a large case-control study

Transcriptional Suppression of the NLRP3 Inflammasome and Cytokine Release in Primary Macrophages by Low-Dose Anthracyclines

Vascular adhesion protein-1 is elevated in primary sclerosing cholangitis, is predictive of clinical outcome and facilitates recruitment of gut-tropic lymphocytes to liver in a substrate-dependent manner.