Lista de obras - Juan A Asenjo - Dominio Público Uruguay

A mixed mechanistic-electrostatic model to explain pH dependence of glycosyl hydrolase enzyme activity.

artículo científico publicado en 2004

A population balance model of enzymatic lysis of microbial cells

artículo científico publicado en 1990

A structured mechanistic model of the kinetics of enzymatic lysis and disruption of yeast cells.

artículo científico publicado en 1988

A theory of protein-resin interaction in hydrophobic interaction chromatography.

artículo científico publicado en 2005

An integrated computational approach can classify VHL missense mutations according to risk of clear cell renal carcinoma.

artículo científico publicado en 2014

Analysis of metabolic networks of Streptomyces leeuwenhoekii C34 by means of a genome scale model: Prediction of modifications that enhance the production of specialized metabolites

artículo científico publicado en 2018

Aqueous two-phase systems for protein separation: A perspective ⬇️

artículo científico publicado el 21 de junio de 2011

Aqueous two-phase systems for protein separation: Phase separation and applications ⬇️

artículo científico publicado el 23 de marzo de 2012

Atacama Database: a platform of the microbiome of the Atacama Desert

scientific article published on 18 September 2019

Atacamycins A-C, 22-membered antitumor macrolactones produced by Streptomyces sp. C38. ⬇️

artículo científico publicado en 2011

Chaxamycins A-D, bioactive ansamycins from a hyper-arid desert Streptomyces sp.

artículo científico publicado en 2011

Chaxapeptin, a Lasso Peptide from Extremotolerant Streptomyces leeuwenhoekii Strain C58 from the Hyperarid Atacama Desert

artículo científico publicado en 2015

Cloning of complete genes for novel hydrolytic enzymes from Antarctic sea water bacteria by use of an improved genome walking technique

artículo científico publicado en 2007

Cloning, expression and decoding of the cold adaptation of a new widely represented thermolabile subtilisin-like protease.

artículo científico publicado en 2012

Cold adaptation, ca2+ dependency and autolytic stability are related features in a highly active cold-adapted trypsin resistant to autoproteolysis engineered for biotechnological applications

artículo científico publicado en 2013

Comparative transcriptional analysis of embryoid body versus two-dimensional differentiation of murine embryonic stem cells.

artículo científico

Continuous modeling of metabolic networks with gene regulation in yeast and in vivo determination of rate parameters.

artículo científico publicado en 2012

Current insights on protein behaviour in hydrophobic interaction chromatography.

artículo científico publicado en 2006

Design and implementation of a high yield production system for recombinant expression of peptides

artículo científico publicado en 2014

Diverse Metabolic Profiles of a Streptomyces Strain Isolated from a Hyper-arid Environment ⬇️

artículo científico publicado el 31 de agosto de 2011

Diversity of culturable actinomycetes in hyper-arid soils of the Atacama Desert, Chile.

artículo científico publicado en 2008

Dynamic flux balance analysis of biomass and lipid production by Antarctic thraustochytrid Oblongichytrium sp. RT2316-13

scientific article published on 18 June 2020

Effect of surface hydrophobicity distribution on retention of ribonucleases in hydrophobic interaction chromatography.

artículo científico publicado en 2004

Effect of the growth conditions on the synthesis of a recombinant beta-1,4-endoglucanase in continuous and fed-batch culture

artículo científico publicado en 2000

Elution relationships to model affinity chromatography using a general rate model.

artículo científico publicado en 2012

Enzymatic lysis of microbial cells.

artículo científico publicado en 2007

Extension of the selection of protein chromatography and the rate model to affinity chromatography

artículo científico publicado el 1 de noviembre de 2010

Extraction of lysozyme and ribonuclease-a using reverse micelles: Limits to protein solubilization.

artículo científico publicado en 1995

Factors affecting the esterification of lauric acid using an immobilized biocatalyst: Enzyme characterization and studies in a well-mixed reactor.

artículo científico publicado en 1995

Genome-scale reconstruction of Salinispora tropica CNB-440 metabolism to study strain-specific adaptation.

artículo científico publicado en 2015

Hydrophobic interaction chromatography for purification of monoPEGylated RNase A

artículo científico publicado en 2012

Identification and Heterologous Expression of the Chaxamycin Biosynthesis Gene Cluster from Streptomyces leeuwenhoekii ⬇️

artículo científico publicado en 2015

Identification of lipase encoding genes from Antarctic seawater bacteria using degenerate primers: expression of a cold-active lipase with high specific activity

artículo científico publicado en 2014

Identification of transcription factors perturbed by the synthesis of high levels of a foreign protein in yeast saccharomyces cerevisiae ⬇️

artículo científico publicado el 8 de junio de 2011

Improvement of the lytic properties of a beta-1,3-glucanase by directed evolution.

artículo científico publicado en 2006

Is it possible to predict the average surface hydrophobicity of a protein using only its amino acid composition?

artículo científico publicado en 2005

Is there a rational method to purify proteins? From expert systems to proteomics.

artículo científico publicado en 2004

Isolation, purification and preliminary characterization of cryophilic proteases of marine origin.

artículo científico publicado en 2001

Kinetic model of BiP- and PDI-mediated protein folding and assembly

artículo científico publicado en 2002

Kinetics of phase separation for polyethylene glycol-phosphate two-phase systems

artículo científico publicado en 1995

Mathematical correlations for predicting protein retention times in hydrophobic interaction chromatography.

artículo científico publicado en 2002

Mathematical modeling of elution curves for a protein mixture in ion exchange chromatography applied to high protein concentration.

artículo científico publicado en 2009

Metabolic analysis of the synthesis of high levels of intracellular human SOD in Saccharomyces cerevisiae rhSOD 2060 411 SGA122.

artículo científico publicado en 2003

Metabolic flux analysis of embryonic stem cells using three distinct differentiation protocols and comparison to gene expression patterns.

artículo científico publicado en 2010

Microbiology of hyper-arid environments: recent insights from the Atacama Desert, Chile.

artículo científico publicado en 2013

Modeling heterocyst pattern formation in cyanobacteria.

artículo científico publicado en 2009

Molecular characterisation of a thermoactive beta-1,3-glucanase from Oerskovia xanthineolytica.

artículo científico publicado en 1996

Molecular cloning of a lytic beta-1,3-glucanase gene from Oerskovia xanthineolytica LLG109. A beta-1,3-glucanase able to selectively permeabilize the yeast cell wall.

artículo científico publicado en 1996

Mutagenesis Objective Search and Selection Tool (MOSST): an algorithm to predict structure-function related mutations in proteins.

artículo científico publicado en 2011

Non-homogeneous biofilm modeling applied to bioleaching processes

artículo científico publicado en 2010

On the kinetics of phase separation in aqueous two-phase systems ⬇️

artículo científico publicado el 26 de junio de 1998

Optimal design of protein production plants with time and size factor process models.

artículo científico publicado en 2000

Optimal operation conditions for protein separation in hydrophobic interaction chromatography

artículo científico publicado en 2006

Optimal process synthesis for the production of multiple recombinant proteins.

artículo científico publicado en 2004

Optimization of a biotechnological multiproduct batch plant design for the manufacture of four different products: A real case scenario.

artículo científico publicado en 2017

Optimization of batch processes involving simultaneous enzymatic and microbial reactions

scientific article published on 01 May 1991

Optimization of enzymatic lysis of yeast.

artículo científico publicado en 1988

Phase separation rates of aqueous two-phase systems: correlation with system properties

scientific article published on 01 July 2002

Predicting the behaviour of proteins in hydrophobic interaction chromatography. 2. Using a statistical description of their surface amino acid distribution.

artículo científico publicado en 2005

Prediction of protein retention in hydrophobic interaction chromatography.

artículo científico publicado en 2005

Prediction of retention times of proteins in hydrophobic interaction chromatography using only their amino acid composition.

artículo científico publicado en 2005

Prediction of the partitioning behaviour of proteins in aqueous two-phase systems using only their amino acid composition.

artículo científico publicado en 2007

Production of cell-penetrating peptides in Escherichia coli using an intein-mediated system.

artículo científico publicado en 2015

Protein partitioning equilibrium between the aqueous poly(ethylene glycol) and salt phases and the solid protein phase in poly(ethylene glycol)-salt two-phase systems.

artículo científico publicado en 1996

Protein purification using chromatography: selection of type, modelling and optimization of operating conditions.

artículo científico publicado en 2009

Rational design of purification processes for recombinant proteins

scientific article published on 01 December 1992

Reducing the allowable kinetic space by constructing ensemble of dynamic models with the same steady-state flux.

artículo científico publicado en 2010

Selection of chromatographic protein purification operations based on physicochemical properties

artículo científico publicado en 1994

Stoichiometric model and flux balance analysis for a mixed culture of Leptospirillum ferriphilum and Ferroplasma acidiphilum.

artículo científico publicado en 2014

Streptomyces atacamensis sp. nov., isolated from an extreme hyper-arid soil of the Atacama Desert, Chile.

artículo científico publicado en 2011

Streptomyces bullii sp. nov., isolated from a hyper-arid Atacama Desert soil.

artículo científico publicado en 2012

Streptomyces deserti sp. nov., isolated from hyper-arid Atacama Desert soil.

artículo científico publicado en 2011

Studies on the purification of peroxidase from horseradish roots using reverse micelles

scientific article published on 01 April 1996

The Monod equation and mass transfer.

artículo científico publicado en 1995

The Streptomyces leeuwenhoekii genome: de novo sequencing and assembly in single contigs of the chromosome, circular plasmid pSLE1 and linear plasmid pSLE2

artículo científico publicado en 2015

The application of aqueous two-phase systems to the purification of pharmaceutical proteins from transgenic sheep milk.

artículo científico publicado en 1997

The rational selection of purification processes for proteins: an expert system for downstream processing design.

artículo científico publicado en 1994

The surface exposed amino acid residues of monomeric proteins determine the partitioning in aqueous two-phase systems

artículo científico publicado en 2002

Viral vectors for the treatment of alcoholism: use of metabolic flux analysis for cell cultivation and vector production.

artículo científico publicado en 2009

Lista de obras de Juan A Asenjo

A mixed mechanistic-electrostatic model to explain pH dependence of glycosyl hydrolase enzyme activity.

A population balance model of enzymatic lysis of microbial cells

A structured mechanistic model of the kinetics of enzymatic lysis and disruption of yeast cells.

A theory of protein-resin interaction in hydrophobic interaction chromatography.

An integrated computational approach can classify VHL missense mutations according to risk of clear cell renal carcinoma.

Analysis of metabolic networks of Streptomyces leeuwenhoekii C34 by means of a genome scale model: Prediction of modifications that enhance the production of specialized metabolites

Aqueous two-phase systems for protein separation: A perspective ⬇️

Aqueous two-phase systems for protein separation: Phase separation and applications ⬇️

Atacama Database: a platform of the microbiome of the Atacama Desert

Atacamycins A-C, 22-membered antitumor macrolactones produced by Streptomyces sp. C38. ⬇️

Chaxamycins A-D, bioactive ansamycins from a hyper-arid desert Streptomyces sp.

Chaxapeptin, a Lasso Peptide from Extremotolerant Streptomyces leeuwenhoekii Strain C58 from the Hyperarid Atacama Desert

Cloning of complete genes for novel hydrolytic enzymes from Antarctic sea water bacteria by use of an improved genome walking technique

Cloning, expression and decoding of the cold adaptation of a new widely represented thermolabile subtilisin-like protease.

Cold adaptation, ca2+ dependency and autolytic stability are related features in a highly active cold-adapted trypsin resistant to autoproteolysis engineered for biotechnological applications

Comparative transcriptional analysis of embryoid body versus two-dimensional differentiation of murine embryonic stem cells.

Continuous modeling of metabolic networks with gene regulation in yeast and in vivo determination of rate parameters.

Current insights on protein behaviour in hydrophobic interaction chromatography.

Design and implementation of a high yield production system for recombinant expression of peptides

Diverse Metabolic Profiles of a Streptomyces Strain Isolated from a Hyper-arid Environment ⬇️

Diversity of culturable actinomycetes in hyper-arid soils of the Atacama Desert, Chile.

Dynamic flux balance analysis of biomass and lipid production by Antarctic thraustochytrid Oblongichytrium sp. RT2316-13

Effect of surface hydrophobicity distribution on retention of ribonucleases in hydrophobic interaction chromatography.

Effect of the growth conditions on the synthesis of a recombinant beta-1,4-endoglucanase in continuous and fed-batch culture

Elution relationships to model affinity chromatography using a general rate model.

Enzymatic lysis of microbial cells.

Extension of the selection of protein chromatography and the rate model to affinity chromatography

Extraction of lysozyme and ribonuclease-a using reverse micelles: Limits to protein solubilization.

Factors affecting the esterification of lauric acid using an immobilized biocatalyst: Enzyme characterization and studies in a well-mixed reactor.

Genome-scale reconstruction of Salinispora tropica CNB-440 metabolism to study strain-specific adaptation.

Hydrophobic interaction chromatography for purification of monoPEGylated RNase A

Identification and Heterologous Expression of the Chaxamycin Biosynthesis Gene Cluster from Streptomyces leeuwenhoekii ⬇️

Identification of lipase encoding genes from Antarctic seawater bacteria using degenerate primers: expression of a cold-active lipase with high specific activity

Identification of transcription factors perturbed by the synthesis of high levels of a foreign protein in yeast saccharomyces cerevisiae ⬇️

Improvement of the lytic properties of a beta-1,3-glucanase by directed evolution.

Is it possible to predict the average surface hydrophobicity of a protein using only its amino acid composition?

Is there a rational method to purify proteins? From expert systems to proteomics.

Isolation, purification and preliminary characterization of cryophilic proteases of marine origin.

Kinetic model of BiP- and PDI-mediated protein folding and assembly

Kinetics of phase separation for polyethylene glycol-phosphate two-phase systems

Mathematical correlations for predicting protein retention times in hydrophobic interaction chromatography.

Mathematical modeling of elution curves for a protein mixture in ion exchange chromatography applied to high protein concentration.

Metabolic analysis of the synthesis of high levels of intracellular human SOD in Saccharomyces cerevisiae rhSOD 2060 411 SGA122.

Metabolic flux analysis of embryonic stem cells using three distinct differentiation protocols and comparison to gene expression patterns.

Microbiology of hyper-arid environments: recent insights from the Atacama Desert, Chile.

Modeling heterocyst pattern formation in cyanobacteria.

Molecular characterisation of a thermoactive beta-1,3-glucanase from Oerskovia xanthineolytica.

Molecular cloning of a lytic beta-1,3-glucanase gene from Oerskovia xanthineolytica LLG109. A beta-1,3-glucanase able to selectively permeabilize the yeast cell wall.

Mutagenesis Objective Search and Selection Tool (MOSST): an algorithm to predict structure-function related mutations in proteins.

Non-homogeneous biofilm modeling applied to bioleaching processes

On the kinetics of phase separation in aqueous two-phase systems ⬇️

Optimal design of protein production plants with time and size factor process models.

Optimal operation conditions for protein separation in hydrophobic interaction chromatography

Optimal process synthesis for the production of multiple recombinant proteins.

Optimization of a biotechnological multiproduct batch plant design for the manufacture of four different products: A real case scenario.

Optimization of batch processes involving simultaneous enzymatic and microbial reactions

Optimization of enzymatic lysis of yeast.

Phase separation rates of aqueous two-phase systems: correlation with system properties

Predicting the behaviour of proteins in hydrophobic interaction chromatography. 2. Using a statistical description of their surface amino acid distribution.

Prediction of protein retention in hydrophobic interaction chromatography.

Prediction of retention times of proteins in hydrophobic interaction chromatography using only their amino acid composition.

Prediction of the partitioning behaviour of proteins in aqueous two-phase systems using only their amino acid composition.

Production of cell-penetrating peptides in Escherichia coli using an intein-mediated system.

Protein partitioning equilibrium between the aqueous poly(ethylene glycol) and salt phases and the solid protein phase in poly(ethylene glycol)-salt two-phase systems.

Protein purification using chromatography: selection of type, modelling and optimization of operating conditions.

Rational design of purification processes for recombinant proteins

Reducing the allowable kinetic space by constructing ensemble of dynamic models with the same steady-state flux.

Selection of chromatographic protein purification operations based on physicochemical properties

Stoichiometric model and flux balance analysis for a mixed culture of Leptospirillum ferriphilum and Ferroplasma acidiphilum.

Streptomyces atacamensis sp. nov., isolated from an extreme hyper-arid soil of the Atacama Desert, Chile.

Streptomyces bullii sp. nov., isolated from a hyper-arid Atacama Desert soil.

Streptomyces deserti sp. nov., isolated from hyper-arid Atacama Desert soil.

Studies on the purification of peroxidase from horseradish roots using reverse micelles

The Monod equation and mass transfer.

The Streptomyces leeuwenhoekii genome: de novo sequencing and assembly in single contigs of the chromosome, circular plasmid pSLE1 and linear plasmid pSLE2

The application of aqueous two-phase systems to the purification of pharmaceutical proteins from transgenic sheep milk.

The rational selection of purification processes for proteins: an expert system for downstream processing design.

The surface exposed amino acid residues of monomeric proteins determine the partitioning in aqueous two-phase systems

Viral vectors for the treatment of alcoholism: use of metabolic flux analysis for cell cultivation and vector production.