Lista de obras - Gethin Thomas - Dominio Público Uruguay

A brilliant breakthrough in OI type V.

artículo científico

A mouse model of early-onset renal failure due to a xanthine dehydrogenase nonsense mutation

artículo científico publicado en 2012

A mouse with an N-Ethyl-N-nitrosourea (ENU) Induced Trp589Arg Galnt3 mutation represents a model for hyperphosphataemic familial tumoural calcinosis

artículo científico publicado en 2012

Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial.

artículo científico publicado en 2014

Association of STAT3 and TNFRSF1A with ankylosing spondylitis in Han Chinese

article

Association ofERAP1, but notIL23R, with ankylosing spondylitis in a Han Chinese population

article

Brief report: high-throughput sequencing of IL23R reveals a low-frequency, nonsynonymous single-nucleotide polymorphism that is associated with ankylosing spondylitis in a Han Chinese population

artículo científico publicado en 2013

Bril: a novel bone-specific modulator of mineralization

scientific journal article

Caveolin-1 deficiency leads to increased susceptibility to cell death and fibrosis in white adipose tissue: characterization of a lipodystrophic model

scientific journal article

Characterization of osteocrin expression in human bone.

artículo científico publicado en 2005

Cisplatin treatment induces a transient increase in tumorigenic potential associated with high interleukin-6 expression in head and neck squamous cell carcinoma.

artículo científico publicado en 2010

Confluence-Induced Squamous Differentiation Is Not Accompanied by Changes in H3K27me3 Repressive Epigenetic Mark

artículo científico

Discovery of candidate serum proteomic and metabolomic biomarkers in ankylosing spondylitis

artículo científico publicado en 2011

Disease-associated polymorphisms in ERAP1 do not alter endoplasmic reticulum stress in patients with ankylosing spondylitis

article

ERAP2 functional knockout in humans does not alter surface heavy chains or HLA-B27, inflammatory cytokines or endoplasmic reticulum stress markers

artículo científico publicado en 2015

Early anti-inflammatory intervention ameliorates axial disease in the proteoglycan-induced spondylitis mouse model of ankylosing spondylitis.

artículo científico publicado en 2017

Epigenetic and gene expression analysis of ankylosing spondylitis-associated loci implicate immune cells and the gut in the disease pathogenesis

artículo científico

Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors

artículo científico publicado en 2012

Expression profiling in spondyloarthropathy synovial biopsies highlights changes in expression of inflammatory genes in conjunction with tissue remodelling genes

artículo científico publicado en 2013

Gene expression profiling reveals a downregulation in immune-associated genes in patients with AS.

artículo científico publicado en 2009

Genetic Variants in ERAP1 and ERAP2 Associated With Immune-Mediated Diseases Influence Protein Expression and the Isoform Profile.

artículo científico publicado en 2017

Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes

artículo científico publicado en 2008

Genetics and genomics of ankylosing spondylitis

scientific article published on January 2010

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

artículo científico publicado en 2010

Human and Murine Osteocalcin Gene Expression: Conserved Tissue Restricted Expression and Divergent Responses to 1,25-Dihydroxyvitamin D3in Vivo

article

Inflammation-driven bone formation in a mouse model of ankylosing spondylitis: sequential not parallel processes.

artículo científico publicado en 2016

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

artículo científico publicado en 2011

Interleukin-23 mediates the intestinal response to microbial β-1,3-glucan and the development of spondyloarthritis pathology in SKG mice

article

Macrophage secretory products induce an inflammatory phenotype in hepatocytes

artículo científico publicado en 2012

Mice with an N-Ethyl-N-Nitrosourea (ENU) Induced Tyr209Asn Mutation in Natriuretic Peptide Receptor 3 (NPR3) Provide a Model for Kyphosis Associated with Activation of the MAPK Signaling Pathway

artículo científico publicado en 2016

N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models

artículo científico publicado en 2015

Osteocrin is a specific ligand of the natriuretic Peptide clearance receptor that modulates bone growth

artículo científico publicado en 2007

Osteocrin, a novel bone-specific secreted protein that modulates the osteoblast phenotype

scientific journal article

Osteocrin--beyond just another bone protein?

artículo científico publicado en 2009

Potential of genome-wide association study data to contribute to better treatments: examples from ankylosing spondylitis

artículo científico publicado en 2011

Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing

artículo científico publicado en 2015

Resveratrol Does Not Benefit Patients With Nonalcoholic Fatty Liver Disease

artículo científico publicado en 2014

Sclerostin regulates release of bone mineral by osteocytes by induction of carbonic anhydrase 2.

artículo científico publicado en 2013

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

artículo científico publicado en 2014

Ski overexpression in skeletal muscle modulates genetic programs that control susceptibility to diet-induced obesity and insulin signaling

artículo científico publicado en 2012

Smg1 haploinsufficiency predisposes to tumor formation and inflammation

artículo científico publicado en 2012

Species-divergent regulation of human and mouse osteocalcin genes by calciotropic hormones

artículo científico publicado en 2000

The IFITM5 mutation c.-14C > T results in an elongated transcript expressed in human bone; and causes varying phenotypic severity of osteogenesis imperfecta type V

artículo científico publicado en 2014

Transgenic Adipose-specific Expression of the Nuclear Receptor RORα Drives a Striking Shift in Fat Distribution and Impairs Glycemic Control.

artículo científico publicado en 2016

Transgenic muscle-specific Nor-1 expression regulates multiple pathways that effect adiposity, metabolism, and endurance

artículo científico publicado en 2013

Treatment of a mouse model of ankylosing spondylitis with exogenous sclerostin has no effect on disease progression.

artículo científico publicado en 2015

Tumor-initiating activity and tumor morphology of HNSCC is modulated by interactions between clonal variants within the tumor

artículo científico publicado en 2010

Vitamin D Action and Regulation of Bone Remodeling: Suppression of Osteoclastogenesis by the Mature Osteoblast

article

Whole blood transcriptional profiling in ankylosing spondylitis identifies novel candidate genes that might contribute to the inflammatory and tissue-destructive disease aspects

artículo científico publicado en 2011

Whole-exome re-sequencing in a family quartet identifies POP1 mutations as the cause of a novel skeletal dysplasia

artículo científico publicado en 2011

β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice

article

Lista de obras de Gethin Thomas

A brilliant breakthrough in OI type V.

A mouse model of early-onset renal failure due to a xanthine dehydrogenase nonsense mutation

A mouse with an N-Ethyl-N-nitrosourea (ENU) Induced Trp589Arg Galnt3 mutation represents a model for hyperphosphataemic familial tumoural calcinosis

Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial.

Association of STAT3 and TNFRSF1A with ankylosing spondylitis in Han Chinese

Association ofERAP1, but notIL23R, with ankylosing spondylitis in a Han Chinese population

Brief report: high-throughput sequencing of IL23R reveals a low-frequency, nonsynonymous single-nucleotide polymorphism that is associated with ankylosing spondylitis in a Han Chinese population

Bril: a novel bone-specific modulator of mineralization

Caveolin-1 deficiency leads to increased susceptibility to cell death and fibrosis in white adipose tissue: characterization of a lipodystrophic model

Characterization of osteocrin expression in human bone.

Cisplatin treatment induces a transient increase in tumorigenic potential associated with high interleukin-6 expression in head and neck squamous cell carcinoma.

Confluence-Induced Squamous Differentiation Is Not Accompanied by Changes in H3K27me3 Repressive Epigenetic Mark

Discovery of candidate serum proteomic and metabolomic biomarkers in ankylosing spondylitis

Disease-associated polymorphisms in ERAP1 do not alter endoplasmic reticulum stress in patients with ankylosing spondylitis

ERAP2 functional knockout in humans does not alter surface heavy chains or HLA-B27, inflammatory cytokines or endoplasmic reticulum stress markers

Early anti-inflammatory intervention ameliorates axial disease in the proteoglycan-induced spondylitis mouse model of ankylosing spondylitis.

Epigenetic and gene expression analysis of ankylosing spondylitis-associated loci implicate immune cells and the gut in the disease pathogenesis

Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors

Expression profiling in spondyloarthropathy synovial biopsies highlights changes in expression of inflammatory genes in conjunction with tissue remodelling genes

Gene expression profiling reveals a downregulation in immune-associated genes in patients with AS.

Genetic Variants in ERAP1 and ERAP2 Associated With Immune-Mediated Diseases Influence Protein Expression and the Isoform Profile.

Genetic analyses in a sample of individuals with high or low BMD shows association with multiple Wnt pathway genes

Genetics and genomics of ankylosing spondylitis

Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci

Human and Murine Osteocalcin Gene Expression: Conserved Tissue Restricted Expression and Divergent Responses to 1,25-Dihydroxyvitamin D3in Vivo

Inflammation-driven bone formation in a mouse model of ankylosing spondylitis: sequential not parallel processes.

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

Interleukin-23 mediates the intestinal response to microbial β-1,3-glucan and the development of spondyloarthritis pathology in SKG mice

Macrophage secretory products induce an inflammatory phenotype in hepatocytes

Mice with an N-Ethyl-N-Nitrosourea (ENU) Induced Tyr209Asn Mutation in Natriuretic Peptide Receptor 3 (NPR3) Provide a Model for Kyphosis Associated with Activation of the MAPK Signaling Pathway

N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models

Osteocrin is a specific ligand of the natriuretic Peptide clearance receptor that modulates bone growth

Osteocrin, a novel bone-specific secreted protein that modulates the osteoblast phenotype

Osteocrin--beyond just another bone protein?

Potential of genome-wide association study data to contribute to better treatments: examples from ankylosing spondylitis

Quantitative gene profiling of long noncoding RNAs with targeted RNA sequencing

Resveratrol Does Not Benefit Patients With Nonalcoholic Fatty Liver Disease

Sclerostin regulates release of bone mineral by osteocytes by induction of carbonic anhydrase 2.

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration

Ski overexpression in skeletal muscle modulates genetic programs that control susceptibility to diet-induced obesity and insulin signaling

Smg1 haploinsufficiency predisposes to tumor formation and inflammation

Species-divergent regulation of human and mouse osteocalcin genes by calciotropic hormones

The IFITM5 mutation c.-14C > T results in an elongated transcript expressed in human bone; and causes varying phenotypic severity of osteogenesis imperfecta type V

Transgenic Adipose-specific Expression of the Nuclear Receptor RORα Drives a Striking Shift in Fat Distribution and Impairs Glycemic Control.

Transgenic muscle-specific Nor-1 expression regulates multiple pathways that effect adiposity, metabolism, and endurance

Treatment of a mouse model of ankylosing spondylitis with exogenous sclerostin has no effect on disease progression.

Tumor-initiating activity and tumor morphology of HNSCC is modulated by interactions between clonal variants within the tumor

Vitamin D Action and Regulation of Bone Remodeling: Suppression of Osteoclastogenesis by the Mature Osteoblast

Whole blood transcriptional profiling in ankylosing spondylitis identifies novel candidate genes that might contribute to the inflammatory and tissue-destructive disease aspects

Whole-exome re-sequencing in a family quartet identifies POP1 mutations as the cause of a novel skeletal dysplasia

β-glucan triggers spondylarthritis and Crohn's disease-like ileitis in SKG mice