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Lista de obras de Peter Leung

<i>TOX3</i> Promotes Ovarian Estrogen Synthesis: An RNA-Sequencing and Network Study

artículo científico publicado en 2020

A mechanism for the intraovarian inhibitory action of estrogen on androgen production

artículo científico publicado en 1979

A molecular mechanism underlying ovarian dysfunction of polycystic ovary syndrome: hyperandrogenism induces epigenetic alterations in the granulosa cells.

artículo científico publicado en 2012

ALK2/ALK3-BMPR2/ACVR2A Mediate BMP2-Induced Downregulation of Pentraxin 3 Expression in Human Granulosa-Lutein Cells.

artículo científico publicado en 2017

ALK4-SMAD2/3-SMAD4 signaling mediates the activin A-induced suppression of PTX3 in human granulosa-lutein cells

artículo científico publicado en 2019

AP-1 Transcription Factors c-FOS and c-JUN Mediate GnRH-Induced Cadherin-11 Expression and Trophoblast Cell Invasion

artículo científico publicado en 2015

Activated protein C as disease-modifying therapy in antenatal preeclampsia: An open-label, single arm safety and efficacy trial

artículo científico publicado en 2018

Activin A Increases Human Trophoblast Invasion by Inducing SNAIL-Mediated MMP2 Up-Regulation Through ALK4.

artículo científico publicado en 2015

Activin A increases human trophoblast invasion by upregulating integrin β1 through ALK4

artículo científico publicado en 2020

Activin A promotes ovarian cancer cell migration by suppressing E-cadherin expression

scientific article published on 20 June 2019

Activin A upregulates PTGS2 expression and increases PGE2 production in human granulosa-lutein cells.

artículo científico publicado en 2016

Activin A, B and AB decrease progesterone production by down-regulating StAR in human granulosa cells.

artículo científico publicado en 2015

Activin A, B, and AB increase human trophoblast cell invasion by up-regulating N-cadherin.

artículo científico publicado en 2014

Activin A-induced increase in LOX activity in human granulosa-lutein cells is mediated by CTGF.

artículo científico publicado en 2016

Activin B induces human endometrial cancer cell adhesion, migration and invasion by up-regulating integrin β3 via SMAD2/3 signaling

artículo científico publicado en 2015

Activin B promotes endometrial cancer cell migration by down-regulating E-cadherin via SMAD-independent MEK-ERK1/2-SNAIL signaling.

artículo científico publicado en 2016

Activin receptor signaling.

artículo científico publicado en 2004

Activin-A up-regulates type I activin receptor mRNA levels in human immortalized extravillous trophoblast cells

artículo científico publicado en 2003

Acute stimulation of human chorionic gonadotropin secretion by recombinant human activin-A in first trimester human trophoblast

scientific article published on 01 July 1993

Adenosine 5'-triphosphate activates nuclear translocation of mitogen-activated protein kinases leading to the induction of early growth response 1 and raf expression in human granulosa-luteal cells.

artículo científico publicado en 2004

Adenosine triphosphate activates mitogen-activated protein kinase in pre-neoplastic and neoplastic ovarian surface epithelial cells.

artículo científico publicado en 2003

Alternative splicing of the androgen receptor in polycystic ovary syndrome

artículo científico publicado en 2015

Amphiregulin induces human ovarian cancer cell invasion by down-regulating E-cadherin expression

artículo científico publicado en 2014

An activator protein 1-like motif mediates 17beta-estradiol repression of gonadotropin-releasing hormone receptor promoter via an estrogen receptor alpha-dependent mechanism in ovarian and breast cancer cells.

artículo científico publicado en 2003

An intraovarian inhibitory action of estrogen on androgen production in vivo

artículo científico publicado en 1978

Androgenic alteration in pathways of C19-steroid metabolism by cultured rat granulosa cells.

artículo científico

Arachidonic acid and cell signalling in the ovary and placenta.

artículo científico publicado en 1993

Arachidonic acid as a stimulatory mediator of luteinizing hormone-releasing hormone action in the rat ovary.

artículo científico publicado en 1989

Autocrine role of gonadotropin-releasing hormone and its receptor in ovarian cancer cell growth

scientific article published on 01 December 2000

BMP15 suppresses progesterone production by down-regulating StAR via ALK3 in human granulosa cells.

artículo científico publicado en 2013

BMP4 and BMP7 Suppress StAR and Progesterone Production via ALK3 and SMAD1/5/8-SMAD4 in Human Granulosa-Lutein Cells

artículo científico publicado en 2015

BMP6 down-regulates GDNF expression through SMAD1/5 and ERK1/2 signaling pathways in human granulosa-lutein cells.

artículo científico publicado en 2018

BMP6 increases TGF-β1 production by up-regulating furin expression in human granulosa-lutein cells

artículo científico publicado en 2019

Betacellulin induces Slug-mediated down-regulation of E-cadherin and cell migration in ovarian cancer cells.

artículo científico publicado en 2016

Biology and physiology of Calbindin-D9k in female reproductive tissues: involvement of steroids and endocrine disruptors

artículo científico publicado en 2005

Bone Morphogenetic Protein 2 Promotes Human Trophoblast Cell Invasion by Inducing Activin A Production

artículo científico publicado en 2018

Bone morphogenetic protein 2 increases lysyl oxidase activity via up-regulation of snail in human granulosa-lutein cells

artículo científico publicado en 2018

Bone morphogenetic protein 2 promotes human trophoblast cell invasion by upregulating N-cadherin via non-canonical SMAD2/3 signaling.

artículo científico publicado en 2018

Bone morphogenetic protein 2 regulates cell-cell communication by down-regulating connexin43 expression in luteinized human granulosa cells

artículo científico publicado en 2016

Bone morphogenetic protein 6 affects cell-cell communication by altering the expression of Connexin43 in human granulosa-lutein cells

artículo científico publicado en 2019

CD40 ligand induces RIP1-dependent, necroptosis-like cell death in low-grade serous but not serous borderline ovarian tumor cells.

artículo científico publicado en 2015

COX2 and PGE2 mediate EGF-induced E-cadherin-independent human ovarian cancer cell invasion.

artículo científico publicado en 2014

Cadherin switching and activation of p120 catenin signaling are mediators of gonadotropin-releasing hormone to promote tumor cell migration and invasion in ovarian cancer.

artículo científico publicado en 2010

Calbindin-D9k gene expression during pregnancy and lactation in the rat

scientific article published on 01 October 1992

Calbindin-D9k gene expression during the perinatal period in the rat: correlation to estrogen receptor expression in uterus

artículo científico publicado en 1993

Calbindin-D9k mRNA is tightly regulated during the estrous cycle in the rat uterus

artículo científico publicado en 1992

Cell growth of ovarian cancer cells is stimulated by xenoestrogens through an estrogen-dependent pathway, but their stimulation of cell growth appears not to be involved in the activation of the mitogen-activated protein kinases ERK-1 and p38.

artículo científico publicado en 2008

Cell motility and spreading are suppressed by HOXA4 in ovarian cancer cells: possible involvement of beta1 integrin.

artículo científico publicado en 2009

Cellular localization of gonadotropin-releasing hormone (GnRH) I and GnRH II in first-trimester human placenta and decidua

artículo científico publicado en 2004

Changes with age in aromatization of testosterone in immature female rats

artículo científico publicado el 1 de diciembre de 1978

Cloning of the porcine Calbindin-D9k complementary deoxyribonucleic acid by anchored polymerase chain reaction technique.

artículo científico publicado en 1992

Coexpression of hepatocyte growth factor-Met: an early step in ovarian carcinogenesis?

artículo científico publicado en 2001

Complex regulation of Calbindin-D(9k) in the mouse placenta and extra-embryonic membrane during mid- and late pregnancy.

artículo científico publicado en 2004

Connective tissue growth factor mediates TGF-β1-induced low-grade serous ovarian tumor cell apoptosis

artículo científico publicado en 2017

Connective tissue growth factor mediates growth differentiation factor 8-induced increase of lysyl oxidase activity in human granulosa-lutein cells.

artículo científico publicado en 2016

Constitutive and conditional cadherin expression in cultured human ovarian surface epithelium: influence of family history of ovarian cancer

artículo científico publicado en 1999

Cytosolic free Ca2+ in human syncytiotrophoblast cells increased by gonadotropin-releasing hormone

artículo científico publicado en 1993

Cytosolic free calcium increased by prostaglandin F2 alpha (PGF2 alpha), gonadotropin-releasing hormone, and angiotensin II in rat granulosa cells and PGF2 alpha in human granulosa cells.

artículo científico publicado en 1992

Decreased PECAM1-mediated TGF-β1 expression in the mid-secretory endometrium in women with recurrent implantation failure.

artículo científico publicado en 2018

Detection of mRNA expression of gonadotropin-releasing hormone and its receptor in normal and neoplastic rat prostates

scientific article published on 01 December 2001

Differential activation of noncanonical SMAD2/SMAD3 signaling by bone morphogenetic proteins causes disproportionate induction of hyaluronan production in immortalized human granulosa cells

artículo científico publicado en 2016

Differential effects of 8-bromo-cyclic AMP on human chorionic gonadotropin (hCG), progesterone and estrogen production by term placental cells.

artículo científico publicado en 1988

Differential effects of cellular fibronectin and plasma fibronectin on ovarian cancer cell adhesion, migration, and invasion

artículo científico publicado el 1 de marzo de 2003

Differential effects of central adrenoceptor agonists on luteinizing hormone release

scientific article published on 01 March 1982

Differential effects of interleukin-1β and transforming growth factor-β1 on the expression of the inflammation-associated protein, ADAMTS-1, in human decidual stromal cells in vitro

artículo científico publicado en 2006

Differential expression of human gonadotropin-releasing hormone receptor gene in pituitary and ovarian cells.

artículo científico

Differential regulation of two forms of gonadotropin-releasing hormone messenger ribonucleic acid by gonadotropins in human immortalized ovarian surface epithelium and ovarian cancer cells.

artículo científico publicado en 2006

Differential role of gonadotropin-releasing hormone on human ovarian epithelial cancer cell invasion.

artículo científico publicado en 2007

Differential role of progesterone receptor isoforms in the transcriptional regulation of human gonadotropin-releasing hormone I (GnRH I) receptor, GnRH I, and GnRH II

artículo científico publicado en 2005

Differential role of protein kinase C in the action of luteinizing hormone-releasing hormone on hormone production in rat ovarian cells

artículo científico publicado en 1989

Divergent differentiation of rat adrenocortical cells is associated with an interruption of angiotensin II-mediated signal transduction

artículo científico publicado el 1 de noviembre de 1992

Dose-dependent effects of gonadotropin releasing hormone on matrix metalloproteinase (MMP)-2, and MMP-9 and tissue specific inhibitor of metalloproteinases-1 messenger ribonucleic acid levels in human decidual Stromal cells in vitro

scientific article published on 01 February 2003

Dysregulated BMP2 in the Placenta May Contribute to Early-Onset Preeclampsia by Regulating Human Trophoblast Expression of Extracellular Matrix and Adhesion Molecules

artículo científico publicado en 2021

E-cadherin inhibits tumor cell growth by suppressing PI3K/Akt signaling via β-catenin-Egr1-mediated PTEN expression.

artículo científico publicado en 2011

EGF-Induced Connexin43 Negatively Regulates Cell Proliferation in Human Ovarian Cancer.

artículo científico publicado en 2015

EGF-induced EMT and invasiveness in serous borderline ovarian tumor cells: a possible step in the transition to low-grade serous carcinoma cells?

artículo científico publicado en 2012

EGF-like growth factors induce COX-2-derived PGE2 production through ERK1/2 in human granulosa cells.

artículo científico publicado en 2013

Effect of an aromatase inhibitor (4-acetoxy-4-androstene-3,17-dione) on the stimulatory action of luteinizing hormone on estradiol-17 beta synthesis by rat preovulatory follicles in vitro.

artículo científico publicado en 1981

Effect of prostaglandin F2 alpha on cytosolic free calcium ion concentrations in rat luteal cells

scientific article published on 01 August 1991

Effects of adenosine 3',5'-cyclic monophosphate, forskolin, and cholera toxin on hormone production in human term placental cells

scientific article published on 01 February 1987

Effects of alterations in maternal thyroid metabolism on embryonic thyroid development in the chick

artículo científico publicado el 1 de junio de 1976

Effects of cyclic adenosine monophosphate on human chorionic gonadotropin and estradiol output by cultured human placental cells.

artículo científico publicado en 1988

Effects of endogenous growth differentiation factor 9 on activin A-induced inhibin B production in human granulosa-lutein cells.

artículo científico publicado en 2009

Effects of growth differentiation factor 8 on steroidogenesis in human granulosa-lutein cells

artículo científico publicado en 2015

Effects of intraventricular norepinephrine on preoptic-anterior hypothalamic electrical activity in the freely-moving rat: modulation by ovarian steroid hormones.

artículo científico publicado en 1981

Effects of prostaglandins and luteinizing hormone-releasing hormone on phosphatidic acid-phosphatidylinositol labeling in rat granulosa cells

artículo científico publicado en 1985

Effects of recombinant activins on steroidogenesis in human granulosa-lutein cells.

artículo científico publicado en 2014

Egr-1 mediates epidermal growth factor-induced downregulation of E-cadherin expression via Slug in human ovarian cancer cells.

artículo científico publicado en 2012

Electrical stimulation of mesencephalic noradrenergic pathway: effects on luteinizing hormone levels in blood of ovariectomized and ovariectomized, steroid-primed rats

artículo científico publicado en 1981

Electrical stimulation of ventral versus dorsal mesencephalic tegmental areas in the conscious rat: effects on luteinizing hormone release.

artículo científico publicado en 1987

Endocrine signaling in ovarian surface epithelium and cancer.

artículo científico publicado en 2006

EpCAM is up-regulated by EGF via ERK1/2 signaling and suppresses human epithelial ovarian cancer cell migration.

artículo científico publicado en 2015

Estradiol regulates gonadotropin-releasing hormone (GnRH) and its receptor gene expression and antagonizes the growth inhibitory effects of GnRH in human ovarian surface epithelial and ovarian cancer cells.

artículo científico publicado en 2001

Estrogen Inhibits Porcine Thecal Androgen Production in vitro

artículo científico publicado el 1 de enero de 1979

Estrogen Treatment of Immature Rats Inhibits Ovarian Androgen Production in Vitro*

artículo científico publicado el 1 de mayo de 1979

Estrogen receptor alpha pathway is involved in leptin-induced ovarian cancer cell growth.

artículo científico publicado en 2010

Estrogen regulates Snail and Slug in the down-regulation of E-cadherin and induces metastatic potential of ovarian cancer cells through estrogen receptor alpha.

artículo científico publicado en 2008

Expression and antiproliferative effect of a second form of gonadotropin-releasing hormone in normal and neoplastic ovarian surface epithelial cells

scientific article published on 01 October 2001

Expression and function of HOXA genes in normal and neoplastic ovarian epithelial cells.

artículo científico publicado en 2008

Expression of ADAMTS-5/implantin in human decidual stromal cells: regulatory effects of cytokines.

artículo científico publicado en 2006

Expression of calbindin-D28k and its regulation by estrogen in the human endometrium during the menstrual cycle

artículo científico publicado el 2 de marzo de 2011

Expression of calbindin-D9k in the early pregnant rat uterus: effects of RU 486 and correlation to estrogen receptor mRNA

scientific article published on 01 June 1994

Expression of leptin receptors and potential effects of leptin on the cell growth and activation of mitogen-activated protein kinases in ovarian cancer cells.

artículo científico publicado en 2004

Expression of the messenger RNA for gonadotropin-releasing hormone and its receptor in human cancer cell lines.

artículo científico publicado en 1998

FOXL2-induced follistatin attenuates activin A-stimulated cell proliferation in human granulosa cell tumors.

artículo científico publicado en 2013

Fibroblast growth factor 2 induces E-cadherin down-regulation via PI3K/Akt/mTOR and MAPK/ERK signaling in ovarian cancer cells

artículo científico publicado en 2013

Follicle-stimulating hormone activates mitogen-activated protein kinase in preneoplastic and neoplastic ovarian surface epithelial cells

artículo científico publicado en 2002

Follicular localization of GDF 8 and its receptors in normal and PCOS ovaries

artículo científico publicado en 2018

Functional consequences of copy number variants in miscarriage.

artículo científico publicado en 2015

Further evidence in support of a short-loop feedback action of estrogen on ovarian androgen production

artículo científico publicado en 1980

G546A polymorphism of growth differentiation factor-9 contributes to the poor outcome of ovarian stimulation in women with diminished ovarian reserve.

artículo científico publicado en 2010

GDNF-Induced Downregulation of miR-145-5p Enhances Human Oocyte Maturation and Cumulus Cell Viability

artículo científico publicado en 2018

Gain of OGP, an estrogen-regulated oviduct-specific glycoprotein, is associated with the development of endometrial hyperplasia and endometrial cancer.

artículo científico publicado en 2004

GnRH regulates trophoblast invasion via RUNX2-mediated MMP2/9 expression.

artículo científico publicado en 2015

GnRH signaling in intrauterine tissues.

artículo científico publicado en 2009

Gonadal steroids regulate the expression of aggrecanases in human endometrial stromal cells in vitro.

artículo científico publicado en 2013

Gonadotrophin-releasing hormone antagonist induces apoptosis in human decidual stromal cells: effect on GADD45α and MAPK signaling.

artículo científico publicado en 2012

Gonadotropin-releasing hormone (GnRH) and cyclic AMP positively regulate inhibin subunit messenger RNA levels in human placental cells

scientific article published on 01 January 1994

Gonadotropin-releasing hormone (GnRH)-I and GnRH-II induce cell growth inhibition in human endometrial cancer cells: involvement of integrin beta3 and focal adhesion kinase.

artículo científico publicado en 2009

Gonadotropin-releasing hormone activates mitogen-activated protein kinase in human ovarian and placental cells.

artículo científico publicado en 2000

Gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor are expressed at tubal ectopic pregnancy implantation sites.

artículo científico publicado en 2016

Gonadotropin-releasing hormone and ovarian cancer: a functional and mechanistic overview.

artículo científico publicado en 2008

Gonadotropin-releasing hormone promotes ovarian cancer cell invasiveness through c-Jun NH2-terminal kinase-mediated activation of matrix metalloproteinase (MMP)-2 and MMP-9.

artículo científico publicado en 2006

Gonadotropin-releasing hormone regulates human trophoblastic cell invasion via TWIST-induced N-cadherin expression

artículo científico publicado en 2015

Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through the GnRH-I receptor and mitogen-activated protein kinase (MAPK)-dependent activation of matrix metalloproteinase (MMP)-2.

artículo científico publicado en 2013

Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the motility of human decidual endometrial stromal cells: possible effect on embryo implantation and pregnancy.

artículo científico publicado en 2015

Gonadotropin-releasing hormone type II induces apoptosis of human endometrial cancer cells by activating GADD45alpha.

artículo científico publicado en 2009

Gonadotropin-releasing hormone-I or -II interacts with IGF-I/Akt but not connexin 43 in human granulosa cell apoptosis.

artículo científico publicado en 2011

Gonadotropin-releasing hormone-I-mediated activation of progesterone receptor contributes to gonadotropin alpha-subunit expression in mouse gonadotrophs.

artículo científico publicado en 2010

Gonadotropin-releasing hormone-II increases membrane type I metalloproteinase production via beta-catenin signaling in ovarian cancer cells.

artículo científico publicado en 2011

Gonadotropin-releasing hormone-mediated phosphorylation of estrogen receptor-alpha contributes to fosB expression in mouse gonadotrophs.

artículo científico publicado en 2009

Gonadotropin-releasing hormones I and II induce apoptosis in human granulosa cells.

artículo científico publicado en 2008

Gonadotropin-stimulated epidermal growth factor receptor expression in human ovarian surface epithelial cells: involvement of cyclic AMP-dependent exchange protein activated by cAMP pathway.

artículo científico publicado en 2008

Gonadotropins activate proteolysis and increase invasion through protein kinase A and phosphatidylinositol 3-kinase pathways in human epithelial ovarian cancer cells.

artículo científico publicado en 2006

Growth Differentiation Factor-8 Decreases StAR Expression Through ALK5-Mediated Smad3 and ERK1/2 Signaling Pathways in Luteinized Human Granulosa Cells

artículo científico publicado en 2015

Growth differentiation factor 8 down-regulates pentraxin 3 in human granulosa cells

artículo científico publicado en 2015

Growth differentiation factor 8 induces SKOV3 ovarian cancer cell migration and E-cadherin down-regulation.

artículo científico publicado en 2016

Growth differentiation factor 8 suppresses cell proliferation by up-regulating CTGF expression in human granulosa cells.

artículo científico publicado en 2015

Growth differentiation factor 9 enhances activin a-induced inhibin B production in human granulosa cells.

artículo científico publicado en 2009

Growth differentiation factor 9 reverses activin A suppression of steroidogenic acute regulatory protein expression and progesterone production in human granulosa-lutein cells

artículo científico publicado en 2010

Growth hormone-releasing hormone antagonist induces apoptosis of human endometrial cancer cells through PKCδ-mediated activation of p53/p21.

artículo científico publicado en 2010

HER2 mediates epidermal growth factor-induced down-regulation of E-cadherin in human ovarian cancer cells.

artículo científico publicado en 2013

HOXA7 in epithelial ovarian cancer: interrelationships between differentiation and clinical features.

artículo científico publicado en 2007

HOXB4 Immunoreactivity in Endometrial Tissues From Women With or Without Endometriosis

artículo científico publicado en 2017

Hepatocyte growth factor promotes in vitro scattering and morphogenesis of human cervical carcinoma cells.

artículo científico publicado en 2000

Homeobox A7 stimulates breast cancer cell proliferation by up-regulating estrogen receptor-alpha

artículo científico publicado en 2013

Homologous and heterologous regulation of gonadotropin-releasing hormone receptor gene expression in preovulatory rat granulosa cells

article

Human ovary and placenta express messenger RNA for multiple activin receptors.

artículo científico publicado en 1999

Human peripheral blood mononuclear cells express gonadotropin-releasing hormone (GnRH), GnRH receptor, and interleukin-2 receptor gamma-chain messenger ribonucleic acids that are regulated by GnRH in vitro

scientific article published on 01 February 1999

Hydrogen peroxide mediates EGF-induced down-regulation of E-cadherin expression via p38 MAPK and snail in human ovarian cancer cells.

artículo científico publicado en 2010

Hypoxia-inducible factor 1 alpha mediates epidermal growth factor-induced down-regulation of E-cadherin expression and cell invasion in human ovarian cancer cells.

artículo científico publicado en 2012

ID3 mediates the TGF-β1-induced suppression of matrix metalloproteinase-1 in human granulosa cells

artículo científico publicado en 2019

Identification of an upstream promoter in the human gonadotropin-releasing hormone receptor gene

scientific article published on 01 April 2000

Identification of estrogen response element in the aquaporin-2 gene that mediates estrogen-induced cell migration and invasion in human endometrial carcinoma.

artículo científico publicado en 2011

Identification of novel isoforms of activin receptor-like kinase 7 (ALK7) generated by alternative splicing and expression of ALK7 and its ligand, Nodal, in human placenta

artículo científico publicado en 2003

Identification of potential metabolic biomarkers of polycystic ovary syndrome in follicular fluid by SWATH mass spectrometry

artículo científico publicado en 2019

Immunolocalization of gonadotropin-releasing hormone (GnRH)-I, GnRH-II, and type I GnRH receptor during follicular development in the human ovary.

artículo científico publicado en 2006

Impact of Axis of GHRH and GHRH Receptor on Cell Viability and Apoptosis of the Placental Choriocarcinoma Cell Line.

artículo científico publicado en 2016

Increased AIF-1-mediated TNF-α expression during implantation phase in IVF cycles with GnRH antagonist protocol

artículo científico publicado en 2018

Induction of polyphosphoinositide breakdown in rat corpus luteum by prostaglandin F2 alpha

scientific article published on 01 July 1986

Influence of the prodrugs 5-fluorocytosine and CPT-11 on ovarian cancer cells using genetically engineered stem cells: tumor-tropic potential and inhibition of ovarian cancer cell growth.

artículo científico publicado en 2010

Inhibition by estradiol-17β of porcine thecal androgen production in vitro

artículo científico publicado el 1 de mayo de 1979

Inhibition of aromatase activity by 8-bromo-cyclic adenosine monophosphate in cultured first-trimester human trophoblast.

artículo científico publicado en 1990

Inhibition of follicle-stimulating hormone- and adenosine-3',5'-cyclic monophosphate-induced progesterone production by calcium and protein kinase C in the rat ovary

scientific article published on 01 February 1988

Inhibition of p53 induces invasion of serous borderline ovarian tumor cells by accentuating PI3K/Akt-mediated suppression of E-cadherin

artículo científico publicado el 25 de octubre de 2010

Inhibition of progestin accumulation by activin-A in human granulosa cells

artículo científico publicado el 1 de julio de 1992

Inositol lipids and LHRH action in the rat ovary

artículo científico publicado en 1989

Integrin β1 mediates epithelial growth factor-induced invasion in human ovarian cancer cells.

artículo científico publicado en 2012

Interaction of prostaglandin F2alpha and gonadotropin-releasing hormone on progesterone and estradiol production in human granulosa-luteal cells

artículo científico publicado en 1997

Interactions of estrogen and androgen with gonadotropins on ovarian progesterone production.

artículo científico publicado en 1979

Interactions of steroids and gonadotropins in the control of steroidogenesis in the ovarian follicle.

artículo científico publicado en 1980

Interplay of pituitary adenylate cyclase-activating polypeptide with a silencer element to regulate the upstream promoter of the human gonadotropin-releasing hormone receptor gene.

artículo científico publicado en 2001

Intracellular calcium and the signaling mechanism of luteinizing hormone-releasing hormone in rat granulosa cells

artículo científico publicado en 1992

Intracellular signaling in the gonads

artículo científico publicado el 1 de agosto de 1992

Intragonadal signalling mechanisms in the control of steroid hormone production

artículo científico publicado el 1 de marzo de 1992

Involvement of cyclin B1 in progesterone-mediated cell growth inhibition, G2/M cell cycle arrest, and apoptosis in human endometrial cell.

artículo científico publicado en 2009

Kisspeptin and GPR54 immunoreactivity in a cohort of 518 patients defines favourable prognosis and clear cell subtype in ovarian carcinoma

artículo científico publicado en 2007

Kisspeptin regulation of human decidual stromal cells motility via FAK-Src intracellular tyrosine kinases

scientific article published on 01 July 2019

LHRH- and (hydroxyproline9) LHRH-stimulated hCG secretion from perifused first-trimester placental cells

scientific article published on 01 January 1993

Lapatinib Inhibits Amphiregulin-induced BeWo Choriocarcinoma Cell Proliferation by Reducing ERK1/2 and AKT Signaling Pathways

scientific article published on 01 May 2019

Leptin receptor is induced in endometriosis and leptin stimulates the growth of endometriotic epithelial cells through the JAK2/STAT3 and ERK pathways

artículo científico publicado en 2012

Lithium Chloride Increases COX-2 Expression and PGE2 Production in a Human Granulosa-Lutein SVOG Cell Line Via a GSK-3β/β-Catenin Signaling Pathway

artículo científico publicado en 2017

Lithium chloride inhibits StAR and progesterone production through GSK-3β and ERK1/2 signaling pathways in human granulosa-lutein cells.

artículo científico publicado en 2017

Loss of Sprouty2 in human high-grade serous ovarian carcinomas promotes EGF-induced E-cadherin down-regulation and cell invasion

artículo científico publicado en 2014

Low Thyroid Hormone in Early Pregnancy Is Associated With an Increased Risk of Gestational Diabetes Mellitus.

artículo científico publicado en 2016

Luteinizing hormone-releasing hormone (LHRH)-induced arachidonic acid release in rat granulosa cells. Role of calcium and protein kinase C

artículo científico publicado en 1987

Luteinizing hormone-releasing hormone stimulates arachidonic acid release in rat granulosa cells

artículo científico publicado en 1985

Mapping of the gonadotropin-releasing hormone (GnRH) receptor gene to human chromosome 4q21.2 by fluorescence in situ hybridization.

artículo científico publicado en 1995

Mechanism of action of TRH: involvement of the phosphatidylinositol (PI) response in the action of TRH in rat anterior pituitary cells.

artículo científico publicado en 1982

Mechanism of action of luteinizing hormone-releasing hormone in rat ovarian cells.

artículo científico publicado en 1989

Mechanism of gonadotropin-releasing hormone (GnRH)-I and -II-induced cell growth inhibition in ovarian cancer cells: role of the GnRH-I receptor and protein kinase C pathway

artículo científico publicado en 2006

Mechanisms involved in ATP-evoked Ca2+ oscillations in isolated human granulosa-luteal cells.

artículo científico publicado en 1997

Mechanisms underlying p53 regulation of PIK3CA transcription in ovarian surface epithelium and in ovarian cancer.

artículo científico publicado en 2008

Metaplastic changes in cultured human ovarian surface epithelium

artículo científico publicado en 1998

MiR-106a increases granulosa cell viability and is down-regulated in women with diminished ovarian reserve.

artículo científico publicado en 2018

Mitogen-activated protein kinases in normal and (pre)neoplastic ovarian surface epithelium

artículo científico publicado en 2003

Molecular biology of gonadotropin-releasing hormone (GnRH)-I, GnRH-II, and their receptors in humans

artículo científico publicado en 2005

Molecular cloning of the full-length cDNA encoding the human calbindin-D9k

artículo científico publicado el 28 de julio de 1992

Molecular mechanism(s) of endocrine-disrupting chemicals and their potent oestrogenicity in diverse cells and tissues that express oestrogen receptors

artículo científico publicado en 2013

Multi-factorial role of GnRH-I and GnRH-II in the human ovary

artículo científico publicado en 2003

Multiple roles of the candidate oncogene ZNF217 in ovarian epithelial neoplastic progression.

artículo científico publicado en 2007

Neurotrophins and glial cell line-derived neurotrophic factor in the ovary: physiological and pathophysiological implications

artículo científico publicado en 2019

Neutrophil apoptosis in preeclampsia, do steroids confound the relationship?

artículo científico publicado en 2004

Nitric oxide and cGMP induce COX-2 expression and PGE2 production in human granulosa cells through CREB signaling pathway.

artículo científico publicado en 2014

Norepinephrine inhibition of pulsatile LH release: receptor specificity.

artículo científico publicado en 1986

Novel dihydroartemisinin dimer containing nitrogen atoms inhibits growth of endometrial cancer cells and may correlate with increasing intracellular peroxynitrite

scientific article published on 29 October 2019

Oocyte-derived BMP15 but not GDF9 down-regulates connexin43 expression and decreases gap junction intercellular communication activity in immortalized human granulosa cells

artículo científico publicado en 2014

Oocyte-somatic cell interactions in the human ovary-novel role of bone morphogenetic proteins and growth differentiation factors

artículo científico publicado en 2016

Overexpression of follicle-stimulating hormone receptor activates oncogenic pathways in preneoplastic ovarian surface epithelial cells.

artículo científico publicado en 2004

Overexpression of wild-type but not C134W mutant FOXL2 enhances GnRH-induced cell apoptosis by increasing GnRH receptor expression in human granulosa cell tumors.

artículo científico publicado en 2013

Oviductal glycoprotein (OVGP1, MUC9): a differentiation-based mucin present in serum of women with ovarian cancer

artículo científico publicado en 2010

Oviductal glycoprotein, a new differentiation-based indicator present in early ovarian epithelial neoplasia and cortical inclusion cysts.

artículo científico publicado en 2004

P-cadherin cooperates with insulin-like growth factor-1 receptor to promote metastatic signaling of gonadotropin-releasing hormone in ovarian cancer via p120 catenin

artículo científico publicado en 2011

P2-purinoreceptor evoked changes in intracellular calcium oscillations in single isolated human granulosa-lutein cells

artículo científico publicado en 1996

Palmitic acid causes insulin resistance in granulosa cells via activation of JNK

scientific article published on 01 May 2019

Perturbation of intracellular calcium ion concentration in single rat granulosa cells by angiotensin II.

artículo científico publicado en 1989

Phoenixin-14 concentrations are increased in association with luteinizing hormone and nesfatin-1 concentrations in women with polycystic ovary syndrome.

artículo científico publicado en 2017

Porcine calbindin-D9k gene: expression in endometrium, myometrium, and placenta in the absence of a functional estrogen response element in intron A.

artículo científico publicado en 1995

Potential role of gonadotrophin-releasing hormone (GnRH)-I and GnRH-II in the ovary and ovarian cancer.

artículo científico publicado en 2003

Presence of activin signal transduction in normal ovarian cells and epithelial ovarian carcinoma.

artículo científico publicado en 2000

Prevalence of Prediabetes Risk in Offspring Born to Mothers with Hyperandrogenism

artículo científico publicado en 2017

Progressive changes in Met-dependent signaling in a human ovarian surface epithelial model of malignant transformation.

artículo científico publicado en 2004

Rapid effect of GNRH1 on follicle-stimulating hormone beta gene expression in LbetaT2 mouse pituitary cells requires the progesterone receptor.

artículo científico publicado en 2009

Recombinant BMP4 and BMP7 downregulate pentraxin 3 in human granulosa cells

artículo científico publicado en 2014

Recombinant BMP4 and BMP7 increase activin A production by up-regulating inhibin βA subunit and furin expression in human granulosa-lutein cells.

artículo científico publicado en 2015

Regulated expression of ADAMTS-12 in human trophoblastic cells: a role for ADAMTS-12 in epithelial cell invasion?

artículo científico publicado en 2011

Regulation of A Disintegrin And Metalloproteinase with ThromboSpondin repeats-1 expression in human endometrial stromal cells by gonadal steroids involves progestins, androgens, and estrogens.

artículo científico publicado en 2006

Regulation of prostaglandin F2alpha-receptor mRNA in human granulosa-luteal cells by human chorionic gonadotrophin and prostaglandin F2alpha

artículo científico publicado en 1998

Role of endocrine and growth factors on the ovarian surface epithelium.

artículo científico publicado en 2007

Role of gonadotropin-releasing hormone as an autocrine growth factor in human ovarian surface epithelium

artículo científico publicado en 2000

Role of mitogen-activated protein kinase in prostaglandin f(2alpha) action in human granulosa-luteal cells.

artículo científico publicado en 2001

Role of protein kinase C in luteinizing hormone-releasing hormone (LHRH)-stimulated progesterone production in rat granulosa cells.

artículo científico publicado en 1987

SMAD-dependent signaling mediates morphogenetic protein 6-induced stimulation of connective tissue growth factor in luteinized human granulosa cells†

scientific article published on 01 August 2019

SMAD1/5 mediates bone morphogenetic protein 2-induced up-regulation of BAMBI expression in human granulosa-lutein cells

artículo científico publicado en 2017

SNAIL mediates TGF-β1-induced down-regulation of pentraxin 3 expression in human granulosa cells.

artículo científico publicado en 2018

SV40 early genes induce neoplastic properties in serous borderline ovarian tumor cells.

artículo científico publicado en 2008

Serous borderline ovarian tumors in long-term culture: phenotypic and genotypic distinction from invasive ovarian carcinomas.

artículo científico publicado en 2008

Sphingosine-1-phosphate induces COX-2 expression and PGE2 production in human granulosa cells through a S1P1/3-mediated YAP signaling.

artículo científico publicado en 2016

Sphingosine-1-phosphate promotes ovarian cancer cell proliferation by disrupting Hippo signaling

artículo científico publicado en 2017

Sprouty2 inhibits amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells.

artículo científico publicado en 2016

Sprouty4 mediates amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells.

artículo científico publicado en 2016

Stepwise activation of the gonadotropic signal transduction pathway, and the ability of prostaglandin F2alpha to inhibit this activated pathway

scientific article published on 01 June 1998

Steroid receptor coactivator-3 is required for progesterone receptor trans-activation of target genes in response to gonadotropin-releasing hormone treatment of pituitary cells.

artículo científico publicado en 2006

Stimulation by prostaglandin F2 alpha of phosphatidic acid-phosphatidylinositol turnover in rat luteal cells

artículo científico publicado en 1983

Stimulation of mitogen-activated protein kinase by gonadotropin-releasing hormone in human granulosa-luteal cells.

artículo científico publicado en 2001

Stimulation of phosphatidic acid and phosphatidylinositol labeling in luteal cells by luteinizing hormone releasing hormone

artículo científico publicado en 1983

Stimulation of progesterone secretion by recombinant follistatin-288 in human granulosa cells.

artículo científico publicado en 1993

Stimulatory Action of Androgen Administration in Vivo on Ovarian Responsiveness to Gonadotropins*

artículo científico publicado el 1 de abril de 1979

Stimulatory Action of Follicle-Stimulating Hormone and Androgens on the Responsiveness of Rat Granulosa Cells to Gonadotropins in Vitro**

artículo científico publicado el 1 de abril de 1979

Suppression of luteinizing hormone secretion by atrial and brain natriuretic peptides in ovariectomized rats.

artículo científico publicado en 1991

Sustained endoplasmic reticulum stress as a cofactor of oxidative stress in decidual cells from patients with early pregnancy loss

artículo científico publicado en 2010

TGF-beta induces serous borderline ovarian tumor cell invasion by activating EMT but triggers apoptosis in low-grade serous ovarian carcinoma cells.

artículo científico publicado en 2012

TGF-β1 Increases GDNF Production by Upregulating the Expression of GDNF and Furin in Human Granulosa-Lutein Cells

scientific article published on 10 January 2020

TGF-β1 Inhibits Human Trophoblast Cell Invasion by Upregulating Connective Tissue Growth Factor Expression.

artículo científico publicado en 2017

TGF-β1 Up-Regulates Connective Tissue Growth Factor Expression in Human Granulosa Cells through Smad and ERK1/2 Signaling Pathways.

artículo científico publicado en 2015

TGF-β1 downregulates StAR expression and decreases progesterone production through Smad3 and ERK1/2 signaling pathways in human granulosa cells

artículo científico publicado en 2014

TGF-β1 induces COX-2 expression and PGE2 production in human granulosa cells through Smad signaling pathways.

artículo científico publicado en 2014

TGF-β1 inhibits human trophoblast cell invasion by upregulating cyclooxygenase-2

scientific article published on 30 June 2018

TGF-β1 promotes hyaluronan synthesis by upregulating hyaluronan synthase 2 expression in human granulosa-lutein cells

artículo científico publicado en 2019

TGF-β1 promotes vitamin D-induced prostaglandin E2 synthesis by upregulating vitamin D receptor expression in human granulosa-lutein cells

scientific article published on 21 January 2020

TGF-β1 stimulates migration of type II endometrial cancer cells by down-regulating PTEN via activation of SMAD and ERK1/2 signaling pathways.

artículo científico publicado en 2016

TGF-β1 up-regulates cadherin-11 expression through Snail: A potential mechanism for human trophoblast cell differentiation.

artículo científico publicado en 2017

TGF-β1 up-regulates connexin43 expression: a potential mechanism for human trophoblast cell differentiation.

artículo científico publicado en 2015

TGFβ1 induces endometrial cancer cell adhesion and migration by up-regulating integrin αvβ3 via SMAD-independent MEK-ERK1/2 signaling

artículo científico publicado en 2017

Targeting gonadotropin-releasing hormone receptor inhibits the early step of ovarian cancer metastasis by modulating tumor-mesothelial adhesion.

artículo científico publicado en 2012

Testosterone restores ovarian aromatase activity in rats treated with a 17,20-lyase inhibitor

artículo científico publicado el 1 de abril de 1979

The HMGA2-IMP2 Pathway Promotes Granulosa Cell Proliferation in Polycystic Ovary Syndrome

scientific article published on 01 April 2019

The PI3K/Akt/mTOR signaling pathway mediates insulin-like growth factor 1-induced E-cadherin down-regulation and cell proliferation in ovarian cancer cells.

artículo científico publicado en 2012

The baboon expresses the calbindin-D9k gene in intestine but not in uterus and placenta: implication for conservation of the gene in primates

artículo científico publicado en 1995

The human gonadotropin-releasing hormone receptor gene: complete structure including multiple promoters, transcription initiation sites, and polyadenylation signals.

artículo científico publicado en 1995

The specificity of the FOXL2 c.402C>G somatic mutation: a survey of solid tumors

artículo científico publicado en 2009

The thyroidal response to chronic goitrogenic stimulation and the persistence of effects of early goitrogenic stimulation

artículo científico publicado en 1976

Toll-like receptors 2 and 4 and the cryopyrin inflammasome in normal pregnancy and pre-eclampsia

artículo científico publicado en 2010

Transcriptional down-regulation of human gonadotropin-releasing hormone (GnRH) receptor gene by GnRH: role of protein kinase C and activating protein 1.

artículo científico publicado en 2000

Transcriptional regulation of the mouse calbindin-D9k gene by the ovarian sex hormone.

artículo científico publicado en 2003

Transcripts of testicular gonadotropin-releasing hormone, steroidogenic enzymes, and intratesticular testosterone levels in infertile men.

artículo científico publicado en 2007

Transfer of maternally injected endocrine disruptors through breast milk during lactation induces neonatal Calbindin-D9k in the rat model.

artículo científico publicado en 2004

Transforming growth factor-α induces human ovarian cancer cell invasion by down-regulating E-cadherin in a Snail-independent manner

artículo científico publicado en 2015

Transforming growth factor-β stimulates human ovarian cancer cell migration by up-regulating connexin43 expression via Smad2/3 signaling

artículo científico publicado en 2015

Transforming growth factor-β1 increases lysyl oxidase expression by downregulating MIR29A in human granulosa lutein cells.

artículo científico publicado en 2016

Transforming growth factor-β1 inhibits trophoblast cell invasion by inducing Snail-mediated down-regulation of vascular endothelial-cadherin protein.

scientific article published on 08 October 2013

Transforming growth factor-β1 up-regulates connexin43 expression in human granulosa cells

artículo científico publicado en 2015

Twist modulates human trophoblastic cell invasion via regulation of N-cadherin.

artículo científico publicado en 2011

Twist regulates cadherin-mediated differentiation and fusion of human trophoblastic cells.

artículo científico publicado en 2011

Type I collagen down-regulates E-cadherin expression by increasing PI3KCA in cancer cells

artículo científico publicado el 4 de marzo de 2011

Type II gonadotropin-releasing hormone stimulates p38 mitogen-activated protein kinase and apoptosis in ovarian cancer cells.

artículo científico publicado en 2004

Uterotrophic effects of testosterone and 5alpha-dihydrotestosterone in intact and ovariectomized immature female rats.

artículo científico

Vascular Endothelial Growth Factor-A (VEGF-A) Mediates Activin A-Induced Human Trophoblast Endothelial-Like Tube Formation.

artículo científico publicado en 2015

Vasopressin rapidly stimulates phosphatidic acid-phosphatidylinositol turnover in rat anterior pituitary cells.

artículo científico publicado en 1985

Whole exome sequencing in recurrent early pregnancy loss

artículo científico publicado en 2016

Wild-type p53 attenuates cancer cell motility by inducing growth differentiation factor-15 expression.

artículo científico publicado en 2011

beta-Adrenergic suppression of progesterone-induced luteinizing hormone surge in ovariectomized, estrogen-primed rats

artículo científico publicado en 1982

hCG-induced Sprouty2 mediates amphiregulin-stimulated COX-2/PGE2 up-regulation in human granulosa cells: a potential mechanism for the OHSS.

artículo científico publicado en 2016